| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D E Dluze. Neuroprotective effects of estrogen upon the nigrostriatal dopaminergic system. Journal of neurocytology. vol 29. issue 5-6. 2001-07-26. PMID:11424955. |
this discussion is followed by a more detailed description of estrogen's actions upon the dopamine transporter, which is hypothesized to serve as one of the major mechanism involved with nigrostriatal dopaminergic neuroprotection. |
2001-07-26 |
2023-08-12 |
mouse |
| M S Szczypka, K Kwok, M D Brot, B T Marck, A M Matsumoto, B A Donahue, R D Palmite. Dopamine production in the caudate putamen restores feeding in dopamine-deficient mice. Neuron. vol 30. issue 3. 2001-07-26. PMID:11430814. |
dopamine-deficient (dd) mice cannot synthesize dopamine (da) in dopaminergic neurons due to selective inactivation of the tyrosine hydroxylase gene in those neurons. |
2001-07-26 |
2023-08-12 |
mouse |
| J K Anderse. Do alterations in glutathione and iron levels contribute to pathology associated with Parkinson's disease? Novartis Foundation symposium. vol 235. 2001-07-19. PMID:11280021. |
dopaminergic nigrostriatal neurons, the predominant cells lost in parkinson's, are believed to be highly prone to oxidative damage due to the propensity for dopamine to auto-oxidize and thereby produce elevated levels of hydrogen peroxide and catecholamine quinones. |
2001-07-19 |
2023-08-12 |
mouse |
| N Sharan, V D Nair, R K Mishr. Modulation of a 40-kDa catecholamine regulated protein by dopamine receptor antagonists. European journal of pharmacology. vol 413. issue 1. 2001-07-12. PMID:11173065. |
these results further suggest that crp40 play an important role in dopaminergic neuronal function and the dopamine d1 receptor-mediated signaling pathway may be involved in the regulation of crp40. |
2001-07-12 |
2023-08-12 |
rat |
| S J Kish, K S Kalasinsky, P Derkach, G A Schmunk, M Guttman, L Ang, V Adams, Y Furukawa, J W Haycoc. Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 5. 2001-07-12. PMID:11282256. |
these changes could reflect either a compensatory downregulation of dopamine biosynthesis in response to prolonged dopaminergic stimulation caused by heroin, or reduced axoplasmic transport of tyrosine hydroxylase. |
2001-07-12 |
2023-08-12 |
human |
| C M Thiel, R K Schwartin. Dopaminergic lateralisation in the forebrain: relations to behavioural asymmetries and anxiety in male Wistar rats. Neuropsychobiology. vol 43. issue 3. 2001-07-12. PMID:11287799. |
dopaminergic lateralisation was assessed by means of a post-mortem analysis of tissue dopamine (da) and dihydroxyphenyl acetic acid (dopac) content. |
2001-07-12 |
2023-08-12 |
rat |
| C M Thiel, R K Schwartin. Dopaminergic lateralisation in the forebrain: relations to behavioural asymmetries and anxiety in male Wistar rats. Neuropsychobiology. vol 43. issue 3. 2001-07-12. PMID:11287799. |
the study indicates that asymmetries in ventral striatal dopamine might contribute to side preferences in thigmotactic scanning while frontal dopaminergic lateralisation might influence emotional processing. |
2001-07-12 |
2023-08-12 |
rat |
| Y Maruyama, H Teraoka, H Iwata, A Kazusaka, S Fujit. Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells. Neurochemistry international. vol 38. issue 7. 2001-07-12. PMID:11290381. |
inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in pc12 rat pheochromocytoma cells. |
2001-07-12 |
2023-08-12 |
rat |
| G E Jaskiw, B K Lipska, F Karoum, D R Weinberge. Exposure of a 'witness rat' to one treated with beta-carboline FG 7142 does not increase dopamine turnover in the medial prefrontal cortex of the 'witness rat'. Neuroscience letters. vol 302. issue 2-3. 2001-07-12. PMID:11290409. |
a method for selectively activating the dopaminergic field of the prefrontal cortex would be highly useful for studies of mesocortical dopamine systems. |
2001-07-12 |
2023-08-12 |
rat |
| T Suhara, F Yasuno, Y Sudo, M Yamamoto, M Inoue, Y Okubo, K Suzuk. Dopamine D2 receptors in the insular cortex and the personality trait of novelty seeking. NeuroImage. vol 13. issue 5. 2001-07-12. PMID:11304084. |
we examined the relation between extrastriatal dopamine d2 receptor binding in living human brain and the personality trait of novelty seeking that has been proposed to be related to dopaminergic function in the brain. |
2001-07-12 |
2023-08-12 |
human |
| J Yuan, B T Callahan, U D McCann, G A Ricaurt. Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity. Journal of neurochemistry. vol 77. issue 5. 2001-07-12. PMID:11389185. |
evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity. |
2001-07-12 |
2023-08-12 |
mouse |
| J Yuan, B T Callahan, U D McCann, G A Ricaurt. Evidence against an essential role of endogenous brain dopamine in methamphetamine-induced dopaminergic neurotoxicity. Journal of neurochemistry. vol 77. issue 5. 2001-07-12. PMID:11389185. |
the present studies examined the role of endogenous dopamine (da) in methamphetamine (meth)-induced dopaminergic neurotoxicity while controlling for temperature-related neuroprotective effects of the test compounds, reserpine and alpha-methyl-p-tyrosine (ampt). |
2001-07-12 |
2023-08-12 |
mouse |
| A Ishisaki, H Hayashi, S Suzuki, K Ozawa, E Mizukoshi, K Miyakawa, M Suzuki, T Imamur. Glutathione S-transferase Pi is a dopamine-inducible suppressor of dopamine-induced apoptosis in PC12 cells. Journal of neurochemistry. vol 77. issue 5. 2001-07-12. PMID:11389187. |
the finding that the neurotransmitter dopamine induces apoptosis in neurons implies the existence of a cellular mechanism by which dopaminergic neurons protect themselves from dopamine-induced apoptosis. |
2001-07-12 |
2023-08-12 |
Not clear |
| W J Smeets, J M Lopez, A Gonzále. Immunohistochemical localization of DARPP-32 in the brain of the lizard, Gekko gecko: co-occurrence with tyrosine hydroxylase. The Journal of comparative neurology. vol 435. issue 2. 2001-07-12. PMID:11391641. |
to assess the relationship between dopaminergic neuronal structures and dopaminoceptive structures in a reptile, single and double immunohistochemical procedures with antibodies directed against darpp-32 (dopamine- and camp-regulated phosphoprotein with an apparent molecular mass of 32,000 daltons),a phosphoprotein related to the dopamine d(1)-receptor, and tyrosine hydroxylase (th) were applied to the brain of the lizard, gekko gecko. |
2001-07-12 |
2023-08-12 |
Not clear |
| M Guttman, D Stewart, D Hussey, A Wilson, S Houle, S Kis. Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD. Neurology. vol 56. issue 11. 2001-07-12. PMID:11402115. |
animal data indicate that chronic exposure to dopaminergic drugs can alter levels of the dopamine transporter (dat), which is critically involved in regulation of synaptic dopamine levels. |
2001-07-12 |
2023-08-12 |
Not clear |
| J Holzschuh, S Ryu, F Aberger, W Drieve. Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mechanisms of development. vol 101. issue 1-2. 2001-07-05. PMID:11231083. |
dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. |
2001-07-05 |
2023-08-12 |
zebrafish |
| J Holzschuh, S Ryu, F Aberger, W Drieve. Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mechanisms of development. vol 101. issue 1-2. 2001-07-05. PMID:11231083. |
to characterize the formation of the dopaminergic system in the developing zebrafish cns, we cloned cdnas encoding tyrosine hydroxylase (th), an enzyme in dopamine synthesis, and the dopamine transporter (dat), a membrane transport protein which terminates dopamine action by re-uptake. |
2001-07-05 |
2023-08-12 |
zebrafish |
| Z Ni, R Bouali-Benazzouz, D Gao, A L Benabid, A Benazzou. Intrasubthalamic injection of 6-hydroxydopamine induces changes in the firing rate and pattern of subthalamic nucleus neurons in the rat. Synapse (New York, N.Y.). vol 40. issue 2. 2001-07-05. PMID:11252026. |
immunohistochemical results showed that intrasubthalamic injection of 6-ohda induced a marked degeneration of dopaminergic cells in the lateral part of the ipsilateral snc, whereas 6-ohda injection into the snc induced a total in situ lesion of dopamine cells. |
2001-07-05 |
2023-08-12 |
rat |
| J N Jaworski, R A Gonzales, P K Randal. Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. European journal of pharmacology. vol 418. issue 3. 2001-07-05. PMID:11343690. |
this study examined the effect of the dopamine d2/d3 receptor antagonist sulpiride (50 mg/kg s.c.) on the dopaminergic response to amphetamine (0.5, 2.0, or 8.0 mg/kg i.p.) |
2001-07-05 |
2023-08-12 |
rat |
| N Törnqvist, L Björklund, I Strömber. Evidence for target-specific nerve fiber outgrowth from subpopulations of grafted dopaminergic neurons: a retrograde tracing study using in oculo and intracranial grafting. Experimental neurology. vol 169. issue 2. 2001-07-05. PMID:11358446. |
in conclusion, significantly more dopamine neurons projected to immature than to mature striatal tissue and thus, a subpopulation of grafted dopaminergic neurons was not projecting into adult striatum. |
2001-07-05 |
2023-08-12 |
Not clear |