| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C R Lee, E D Abercrombie, J M Teppe. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501605. |
we used this technique to explore the relation between the firing pattern of dopaminergic neurons and extracellular dopamine levels in the neostriatum in vivo. |
2005-01-13 |
2023-08-12 |
Not clear |
| C R Lee, E D Abercrombie, J M Teppe. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501605. |
specifically, we tested whether an increase in burst firing in dopaminergic neurons produced by increased pallidal activity led to increased extracellular dopamine levels in the neostriatum. |
2005-01-13 |
2023-08-12 |
Not clear |
| C R Lee, E D Abercrombie, J M Teppe. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501605. |
single unit extracellular recording combined with simultaneous microdialysis was used to measure the firing rates and patterns of dopaminergic neurons and extracellular striatal dopamine levels, respectively, during bicuculline-induced excitation of the globus pallidus. |
2005-01-13 |
2023-08-12 |
Not clear |
| C R Lee, E D Abercrombie, J M Teppe. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501605. |
pallidal excitation resulted in a marked increase in burst firing in dopaminergic neurons along with only a slight increase in firing rate, but produced a significant elevation (approximately 45%) in neostriatal dopamine levels. |
2005-01-13 |
2023-08-12 |
Not clear |
| C R Lee, E D Abercrombie, J M Teppe. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501605. |
these data suggest that afferent-induced burst firing in dopaminergic neurons leads to an increase in extracellular dopamine levels in the neostriatum when compared with less bursty patterns with similar overall firing rates. |
2005-01-13 |
2023-08-12 |
Not clear |
| Ingmar H A Franken, Vincent M Hendriks, Cornelis J Stam, Wim Van den Brin. A role for dopamine in the processing of drug cues in heroin dependent patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 6. 2005-01-13. PMID:15589390. |
the present study tests the hypothesis that enhanced attention for heroin cues is mediated by the dopaminergic system using haloperidol as dopamine antagonist. |
2005-01-13 |
2023-08-12 |
Not clear |
| Rumiko Kurosaki, Yasuko Muramatsu, Hiroyuki Kato, Tsutomu Arak. Biochemical, behavioral and immunohistochemical alterations in MPTP-treated mouse model of Parkinson's disease. Pharmacology, biochemistry, and behavior. vol 78. issue 1. 2005-01-07. PMID:15159144. |
the immunohistochemical study has shown that the acute treatment with mptp caused severe loss of tyrosine hydroxylase (th)- and dopamine transporter (dat)-immunoreactive dopaminergic neurons and marked increase in glial fibrillary acidic protein (gfap)-immunoreactive astrocytes in the striatum and the substantia nigra. |
2005-01-07 |
2023-08-12 |
mouse |
| Zsolt Juranyi, Nora Sziray, Bernadett Marko, Gyorgy Levay, Laszlo G Harsin. AMPA receptor blockade potentiates the stimulatory effect of L-DOPA on dopamine release in dopamine-deficient corticostriatal slice preparation. Critical reviews in neurobiology. vol 16. issue 1-2. 2005-01-05. PMID:15581408. |
electrical stimulation of the cortical part increased the release of [3h]dopamine from the striatal part of the slices, and this release was found to be higher after lesion of the nigrostriatal dopaminergic pathway with 6-hydroxydopamine. |
2005-01-05 |
2023-08-12 |
rat |
| Vandana Zaman, Matthew E Nelson, Greg A Gerhardt, Baerbel Rohre. Neurodegenerative alterations in the nigrostriatal system of trkB hypomorphic mice. Experimental neurology. vol 190. issue 2. 2004-12-29. PMID:15530873. |
to further evaluate the role of trkb in the nigrostriatal pathway, we studied neurotrophin levels, dopamine metabolism, and morphology of dopaminergic neurons of the substantia nigra (sn-da) in young adult hypomorphic trkb mice (trkbfbz/fbz), which express only approximately 25% of wild type levels of trkb. |
2004-12-29 |
2023-08-12 |
mouse |
| K Magyar, M Pálfi, T Tábi, H Kalász, B Szende, E Szök. Pharmacological aspects of (-)-deprenyl. Current medicinal chemistry. vol 11. issue 15. 2004-12-23. PMID:15279565. |
beside its dopamine potentiating effect, it renders protection against a number of dopaminergic, cholinergic and noradrenergic neurotoxins with a complex mechanism of action. |
2004-12-23 |
2023-08-12 |
Not clear |
| R Ventura, T Pascucci, M V Catania, S A Musumeci, S Puglisi-Allegr. Object recognition impairment in Fmr1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex. Behavioural pharmacology. vol 15. issue 5-6. 2004-12-22. PMID:15343070. |
in agreement with behavioural data, amphetamine produced a greater increase in dopamine release in the prefrontal cortex of fmr1 knockout compared with the wild-type mice, while a weak striatal dopaminergic response was observed in fmr1 knockout mice. |
2004-12-22 |
2023-08-12 |
mouse |
| E Bálint, T Kitka, G Zachar, A Adám, H C Hemmings, A Csilla. Abundance and location of DARPP-32 in striato-tegmental circuits of domestic chicks. Journal of chemical neuroanatomy. vol 28. issue 1-2. 2004-12-22. PMID:15363488. |
to label the dopaminergic structures, anti-tyrosine hydroxylase was used and darpp-32 (dopamine and camp regulated phosphoprotein) was a marker of dopaminoceptive elements. |
2004-12-22 |
2023-08-12 |
chicken |
| David M Pache, Sabela Fernández-Pérez, Robert D E Sewel. Buspirone differentially modifies short-term memory function in a combined delayed matching/non-matching to position task. European journal of pharmacology. vol 477. issue 3. 2004-12-21. PMID:14522358. |
thus, the findings suggest that partial 5-ht(1a) receptor activation compromises cognitive function to a greater extent than full 5-ht(1a) receptor activation, although a dopaminergic component cannot be excluded since buspirone possesses some dopamine d2 receptor antagonist activity. |
2004-12-21 |
2023-08-12 |
rat |
| F L van Muiswinkel, R A I de Vos, J G J M Bol, G Andringa, E N H Jansen Steur, D Ross, D Siegel, B Drukarc. Expression of NAD(P)H:quinone oxidoreductase in the normal and Parkinsonian substantia nigra. Neurobiology of aging. vol 25. issue 9. 2004-12-21. PMID:15312971. |
dopamine (da) autooxidation, and consequent formation of neurotoxic da-derived quinones and reactive oxygen species, has been implicated in dopaminergic cell death and, hence, in the pathogenesis of parkinson's disease (pd). |
2004-12-21 |
2023-08-12 |
Not clear |
| Hsiao-Sui Lo, Hsueh-Cheng Chiang, Anya M Y Lin, Han-Yun Chiang, Yeh-Chiu Chu, Lung-Sen Ka. Synergistic effects of dopamine and Zn2+ on the induction of PC12 cell death and dopamine depletion in the striatum: possible implication in the pathogenesis of Parkinson's disease. Neurobiology of disease. vol 17. issue 1. 2004-12-21. PMID:15350965. |
thus, both dopamine oxidation and zn(2+) are possibly linked to the degeneration of dopaminergic neurons. |
2004-12-21 |
2023-08-12 |
Not clear |
| Davor Stanic, Wanida Tripanichkul, John Drago, David I Finkelstein, Malcolm K Horn. Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364022. |
lesioning of dopaminergic substantia nigra pars compacta (snpc) neurons leads to depletion of dopamine (da) and dopaminergic axons in the dorsal striatum, followed by subsequent compensatory sprouting of dopaminergic fibers and striatal reinnervation. |
2004-12-21 |
2023-08-12 |
rat |
| Davor Stanic, Wanida Tripanichkul, John Drago, David I Finkelstein, Malcolm K Horn. Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364022. |
following partial snpc lesions, density of dopamine transporter (dat) immunoreactive (-ir) terminals in the dorsal striatum returned to normal within 16 weeks of injury, suggesting that dopaminergic reinnervation of the striatum was complete. |
2004-12-21 |
2023-08-12 |
rat |
| Tomás González-Hernández, Pedro Barroso-Chinea, Manuel Rodrígue. Response of the GABAergic and dopaminergic mesostriatal projections to the lesion of the contralateral dopaminergic mesostriatal pathway in the rat. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 9. 2004-12-21. PMID:15372592. |
although dopamine is the main neurotransmitter in the mesostriatal system, recent studies indicate the existence of two nigrostriatal gabaergic projections: one arising from neurons immunoreactive for gaba, glutamic acid decarboxylase (gad67), and parvalbumin (pv) lying in the substantia nigra pars reticulata (nigrostriatal gaba cells) and the other arising from a subpopulation of dopaminergic neurons lying in the substantia nigra pars compacta and ventral tegmental area, which under normal conditions, contains mrna for gad65 (one of the two isoforms of glutamic acid decarboxylase), but which is not immunoreactive for gaba and gad65 (nigrostriatal dopaminergic [da]/gaba cells). |
2004-12-21 |
2023-08-12 |
rat |
| Samina S Riaz, Spyridon Theofilopoulos, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The differentiation potential of human foetal neuronal progenitor cells in vitro. Brain research. Developmental brain research. vol 153. issue 1. 2004-12-21. PMID:15464216. |
positive immunoreactivity to tyrosine hydroxylase (th) and raised levels of dopamine (da) and its metabolite, 3,4-dihydroxyphenylacetic acid (dopac), secreted into culture medium, were used to indicate the presence of the dopaminergic neuronal phenotype, i.e., active th. |
2004-12-21 |
2023-08-12 |
human |
| Samina S Riaz, Spyridon Theofilopoulos, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The differentiation potential of human foetal neuronal progenitor cells in vitro. Brain research. Developmental brain research. vol 153. issue 1. 2004-12-21. PMID:15464216. |
the brain-derived neurotrophic factor (bdnf) (50 ng/ml), glial-derived neurotrophic factor (gdnf) (10 ng/ml) and interleukin-1 beta (il-1 beta) (10 ng/ml) also had positive effects in promoting neural progenitor cell differentiation towards the dopaminergic phenotype in the presence of dopamine (10 microm) and forskolin (fsk) (10 microm). |
2004-12-21 |
2023-08-12 |
human |