| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianmin Zeng, Jingli Cai, Jia Chen, Yongquan Luo, Zhi-Bing You, Erin Fotter, Yun Wang, Brandon Harvey, Takumi Miura, Cristina Backman, Guann-Juh Chen, Mahendra S Rao, William J Free. Dopaminergic differentiation of human embryonic stem cells. Stem cells (Dayton, Ohio). vol 22. issue 6. 2005-04-01. PMID:15536184. |
differentiated cells expressed other markers of dopaminergic neurons, including the dopamine transporter, aromatic amino acid decarboxylase, and the transcription factors associated with neuronal and dopaminergic differentiation, sox1, nurr1, ptx3, and lmx1b. |
2005-04-01 |
2023-08-12 |
human |
| B Ribeiro Do Couto, M A Aguilar, C Manzanedo, M Rodríguez-Arias, J Miñarr. NMDA glutamate but not dopamine antagonists blocks drug-induced reinstatement of morphine place preference. Brain research bulletin. vol 64. issue 6. 2005-04-01. PMID:15639545. |
following extinction of a place preference induced by morphine (40 mg/kg), a non-contingent injection of the dopaminergic antagonists sch 23390 (0.125, 0.5 mg/kg), raclopride (0.3, 1.2 mg/kg), haloperidol (0.1, 0.2 mg/kg) and the dopamine (da) release inhibitor cgs 10746b (1, 10 mg/kg) or glutamatergic nmda antagonists memantine (10, 20, 40 mg/kg) and mk-801 (0.1, 0.2, 0.3 mg/kg) alone or with 10 mg/kg morphine was given. |
2005-04-01 |
2023-08-12 |
mouse |
| Robert Hering, Karsten M Strauss, Xiao Tao, Andreas Bauer, Dirk Woitalla, Eva-Maria Mietz, Slobodanka Petrovic, Peter Bauer, Wilhelm Schaible, Thomas Müller, Ludger Schöls, Christine Klein, Daniela Berg, Philipp T Meyer, Jörg B Schulz, Bernd Wollnik, Liang Tong, Rejko Krüger, Olaf Ries. Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). Human mutation. vol 24. issue 4. 2005-03-31. PMID:15365989. |
in the patient, a substantial reduction of dopamine uptake transporter (dat) binding was found in the striatum using [(18)f]fp-cit and pet, indicating a serious loss of presynaptic dopaminergic afferents. |
2005-03-31 |
2023-08-12 |
Not clear |
| Iu V Vakhitova, R S Iamidanov, S B Seredini. [Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain]. Eksperimental'naia i klinicheskaia farmakologiia. vol 67. issue 4. 2005-03-31. PMID:15500036. |
in the initial stage (first hours) of the drug action, the dopaminergic effects are related to an increase in the dopamine release. |
2005-03-31 |
2023-08-12 |
rat |
| Shih-Jen Tsa. Dopamine receptor downregulation: an alternative strategy for schizophrenia treatment. Medical hypotheses. vol 63. issue 6. 2005-03-31. PMID:15504573. |
the cause of schizophrenia is still unknown and the simplest formulation of the "dopamine hypothesis" posits that schizophrenia results from dopaminergic hyperactivity. |
2005-03-31 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Dopamine receptor downregulation: an alternative strategy for schizophrenia treatment. Medical hypotheses. vol 63. issue 6. 2005-03-31. PMID:15504573. |
under the hypothesis of dopaminergic hyperactivity in schizophrenia, antipsychotics blocking the dopamine d2 receptor (drd2) and other approaches to reduce dopamine (da) transmission have been used to treat schizophrenia. |
2005-03-31 |
2023-08-12 |
Not clear |
| Marie A Pezze, Joram Feldo. Mesolimbic dopaminergic pathways in fear conditioning. Progress in neurobiology. vol 74. issue 5. 2005-03-29. PMID:15582224. |
the aim of this review is to clarify the complex actions of dopamine in fear conditioning with respect to the wide-spread distribution of dopaminergic innervation over structures constituting the fear related circuitry. |
2005-03-29 |
2023-08-12 |
Not clear |
| Thomas Munsch, Yuchio Yanagawa, Kunihiko Obata, Hans-Christian Pap. Dopaminergic control of local interneuron activity in the thalamus. The European journal of neuroscience. vol 21. issue 1. 2005-03-29. PMID:15654868. |
the dorsal lateral geniculate nucleus (dlgn), the major thalamic station of the visual pathway, contains a fairly large number of dopaminergic terminals, and dopamine was found to reduce spontaneous and visually evoked activity in the dlgn in vivo. |
2005-03-29 |
2023-08-12 |
mouse |
| Maryka Quik, Silvia Vailati, Tanuja Bordia, Jennifer M Kulak, Hong Fan, J Michael McIntosh, Francesco Clementi, Cecilia Gott. Subunit composition of nicotinic receptors in monkey striatum: effect of treatments with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA. Molecular pharmacology. vol 67. issue 1. 2005-03-28. PMID:15470079. |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment decreased alpha6 and beta3 subunit immunoreactivity by approximately 80% in parallel with the dopamine transporter, suggesting that they are predominantly expressed on nigrostriatal dopaminergic projections. |
2005-03-28 |
2023-08-12 |
monkey |
| Alda M Ambrósio, James L Kennedy, Fabio Macciardi, Cathy Barr, Maria J Soares, Catarina R Oliveira, Carlos N Pat. No evidence of association or linkage disequilibrium between polymorphisms in the 5' upstream and coding regions of the dopamine D4 receptor gene and schizophrenia in a Portuguese population. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 125B. issue 1. 2005-03-21. PMID:14755438. |
alterations in dopaminergic system have been implicated in the pathophysiology of this disease for many years, and this study was performed to assess the possible involvement of the dopamine d4 receptor (drd4) gene polymorphisms either in the 5' upstream or in the coding regions, in the etiology of schizophrenia. |
2005-03-21 |
2023-08-12 |
Not clear |
| Chandra M Coleman, Wendi S Neckameye. Substrate regulation of serotonin and dopamine synthesis in Drosophila. Invertebrate neuroscience : IN. vol 5. issue 2. 2005-03-15. PMID:15480914. |
deficiencies in dtph could affect the production of dopamine and serotonin, and thus dopaminergic and serotonergic signaling pathways. |
2005-03-15 |
2023-08-12 |
drosophila_melanogaster |
| Brian K Barlow, Eric K Richfield, Deborah A Cory-Slechta, Mona Thiruchelva. A fetal risk factor for Parkinson's disease. Developmental neuroscience. vol 26. issue 1. 2005-03-15. PMID:15509894. |
this study hypothesized that prenatal exposure to pesticides would disrupt the development of the nigrostriatal dopamine (da) system and enhance its vulnerability to dopaminergic neurotoxicant exposures later in life. |
2005-03-15 |
2023-08-12 |
mouse |
| Gonzalo Bustos, Jorge Abarca, Jorge Campusano, Victor Bustos, Viviana Noriega, Esteban Aliag. Functional interactions between somatodendritic dopamine release, glutamate receptors and brain-derived neurotrophic factor expression in mesencephalic structures of the brain. Brain research. Brain research reviews. vol 47. issue 1-3. 2005-03-15. PMID:15572168. |
dopaminergic nigrostriatal neurons may be considered as bipolar functional entities since they are endowed with the ability to synthesize, store and release the transmitter dopamine (da) at the somatodendritic level in the substantia nigra (sn). |
2005-03-15 |
2023-08-12 |
Not clear |
| Houbo Jiang, Qian Jiang, Jian Fen. Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter. The Journal of biological chemistry. vol 279. issue 52. 2005-03-14. PMID:15492001. |
here we show that parkin significantly increased dopamine uptake in the human dopaminergic neuroblastoma cell line sh-sy5y. |
2005-03-14 |
2023-08-12 |
human |
| Houbo Jiang, Qian Jiang, Jian Fen. Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter. The Journal of biological chemistry. vol 279. issue 52. 2005-03-14. PMID:15492001. |
this function of parkin would enhance the precision of dopaminergic transmission, increase the efficiency of dopamine utilization, and reduce dopamine toxicity on neighboring cells. |
2005-03-14 |
2023-08-12 |
human |
| Samuel Saporta, Alison E Willing, Rania Shamekh, Paula Bickford, Daniel Paredes, Don F Camero. Rapid differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor. Brain research bulletin. vol 64. issue 4. 2005-03-14. PMID:15561470. |
snac tissue constructs also released dopamine (da) when stimulated with kcl, suggesting that th-positive nt2n neurons in the snac adopted a functional dopaminergic phenotype. |
2005-03-14 |
2023-08-12 |
human |
| Djebli NourEddine, Slimani Miloud, Aoues Abdelkade. Effect of lead exposure on dopaminergic transmission in the rat brain. Toxicology. vol 207. issue 3. 2005-03-11. PMID:15664264. |
the collected data showed a clear inhibition of the uptake of 3h-da with an ic50 of 3.5 x 10(-5)m. this inhibition of the uptake of dopamine suggests that the behavioral effects of lead may be involved in dopaminergic neurotransmission. |
2005-03-11 |
2023-08-12 |
rat |
| Yasushi Kitaoka, Toshio Kuma. Modulation of retinal dopaminergic cells by nitric oxide. A protective effect on NMDA-induced retinal injury. In vivo (Athens, Greece). vol 18. issue 3. 2005-03-07. PMID:15341186. |
retinal dopaminergic cells can be detected by the immunohistochemical staining of tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis. |
2005-03-07 |
2023-08-12 |
Not clear |
| Omer Akyol, S Salih Zoroglu, Ferah Armutcu, Semsettin Sahin, Ahmet Gure. Nitric oxide as a physiopathological factor in neuropsychiatric disorders. In vivo (Athens, Greece). vol 18. issue 3. 2005-03-07. PMID:15341194. |
for example, the dopamine hypothesis states that schizophrenia is the result of dopaminergic hyperactivity. |
2005-03-07 |
2023-08-12 |
human |
| Shu-Peng Li, Moon Seok Park, Jong Hun Kim, Myeong Ok Ki. Chronic nicotine and smoke treatment modulate dopaminergic activities in ventral tegmental area and nucleus accumbens and the gamma-aminobutyric acid type B receptor expression of the rat prefrontal cortex. Journal of neuroscience research. vol 78. issue 6. 2005-03-07. PMID:15521060. |
to explore further the relationship between the mesencephalic dopaminergic neurons and pfc gabaergic neurons, we investigated the effects of nicotine and passive exposure to cigarette smoke on the regulation of tyrosine hydroxylase (th) in vta and substantia nigra (snc) and dopamine (da) d1 receptor levels in nucleus accumbens (nac) and caudate-putamen (cpu). |
2005-03-07 |
2023-08-12 |
rat |