| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ph Quintin, P Thoma. [Efficacy of atypical antipsychotics in depressive syndromes]. L'Encephale. vol 30. issue 6. 2005-07-08. PMID:15738862. |
amisulpride is an unique atypical antipsychotic that selectively blocks dopamine receptors presynaptically in the frontal cortex, possibly enhancing dopaminergic transmission. |
2005-07-08 |
2023-08-12 |
Not clear |
| Beata Karolewicz, Violetta Klimek, He Zhu, Katalin Szebeni, Emily Nail, Craig A Stockmeier, Laurel Johnson, Gregory A Ordwa. Effects of depression, cigarette smoking, and age on monoamine oxidase B in amygdaloid nuclei. Brain research. vol 1043. issue 1-2. 2005-07-08. PMID:15862518. |
monoamine oxidase-b (mao-b) is a key enzyme in the catabolism of biogenic amines, including dopamine, and alterations in this enzyme may underlie dopaminergic abnormalities associated with depression. |
2005-07-08 |
2023-08-12 |
human |
| b' Leonid Yavich, Heikki Tanila, Saila Veps\\xc3\\xa4l\\xc3\\xa4inen, Pekka J\\xc3\\xa4k\\xc3\\xa4l\\xc3\\xa. Role of alpha-synuclein in presynaptic dopamine recruitment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 49. 2005-07-07. PMID:15590933.' |
repeated electrical stimulations of ascending dopaminergic pathways decreased the capacity of the readily releasable pool (rrp) and temporarily increased its refilling rate, significantly slowing the rate of dopamine decline in mice with normally expressed alpha-synuclein. |
2005-07-07 |
2023-08-12 |
mouse |
| Bo Zhang, Yueping Hou, James L Voog. Effects of opioid antagonism on prolactin secretion and c-Fos/TH expression during lactation in rats. Endocrine. vol 25. issue 2. 2005-07-07. PMID:15711026. |
many studies have established that dopamine (da) secreted by tuberoinfundibular dopaminergic (tida) neurons in the hypothalamus is the major inhibitory factor controlling prolactin (prl) secretion from the anterior pituitary. |
2005-07-07 |
2023-08-12 |
rat |
| S Sekaran, J Cunningham, M J Neal, N A Hartell, M B A Djamgo. Nitric oxide release is induced by dopamine during illumination of the carp retina: serial neurochemical control of light adaptation. The European journal of neuroscience. vol 21. issue 8. 2005-07-05. PMID:15869516. |
application of exogenous dopamine to retinas in the dark significantly enhanced the basal production of nitric oxide and importantly, inhibition of endogenous dopaminergic activity completely suppressed the light-evoked nitric oxide release. |
2005-07-05 |
2023-08-12 |
Not clear |
| Lance A Smith, Michael J Jackson, Ghassan Al-Barghouthy, Sarah Rose, Mikko Kuoppamaki, Warren Olanow, Peter Jenne. Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 3. 2005-06-30. PMID:15490461. |
long-acting dopamine agonist drugs induce a lower incidence of dyskinesia in mptp-treated primates and patients with parkinson's disease compared to pulsatile treatment with levodopa, supporting the concept of continuous dopaminergic stimulation as a means of dyskinesia avoidance. |
2005-06-30 |
2023-08-12 |
Not clear |
| Abed A Al-Jahmany, Gerhard Schultheiss, Martin Diene. Effects of dopamine on ion transport across the rat distal colon. Pflugers Archiv : European journal of physiology. vol 448. issue 6. 2005-06-28. PMID:15235915. |
the alpha-adrenoceptor blocker phentolamine and the inhibitors of dopamine-2-like (d(2)-like) receptors l-741,626 and l-745,870 inhibited the dopamine response, suggesting a contribution of adrenergic and dopaminergic receptors. |
2005-06-28 |
2023-08-12 |
rat |
| Ji-Young Choi, Eun-Hee Jang, Chang-Shin Park, Ju-Hee Kan. Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity. Free radical biology & medicine. vol 38. issue 6. 2005-06-28. PMID:15721991. |
these results suggest that dio may increase the vulnerability of dopaminergic neurons to mptp via increased levels of reactive oxygen and nitrogen species, and the role of nnos phosphorylation in the mptp toxicities and dopamine homeostasis should be further evaluated. |
2005-06-28 |
2023-08-12 |
mouse |
| Sanjeet Pakrasi, John T O'Brie. Emission tomography in dementia. Nuclear medicine communications. vol 26. issue 3. 2005-06-28. PMID:15722899. |
in dementia with lewy bodies medial parietal and occipital perfusion deficits are seen together with pre-synaptic and post-synaptic dopaminergic changes, most particularly a reduction in the striatal pre-synaptic dopamine transporter which can be visualized using appropriate ligands (e.g., (123)i-fp-cit). |
2005-06-28 |
2023-08-12 |
Not clear |
| Neal R Swerdlow, Ronald Kuczenski, Jana C Goins, Sarah K Crain, Lillian T Ma, Michele J Bongiovanni, Jody M Shoemake. Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists. Pharmacology, biochemistry, and behavior. vol 80. issue 2. 2005-06-24. PMID:15680173. |
the disruption of prepulse inhibition (ppi) in rats by dopamine (da) agonists is used to study the neural basis of strain differences in dopaminergic function. |
2005-06-24 |
2023-08-12 |
rat |
| David Eilam, Henry Szechtma. Psychostimulant-induced behavior as an animal model of obsessive-compulsive disorder: an ethological approach to the form of compulsive rituals. CNS spectrums. vol 10. issue 3. 2005-06-24. PMID:15744221. |
considering that the induction of compulsive behavior in the rat model involves chronic hyperstimulation of dopamine receptors, this raises the possibility that dopaminergic mechanisms may play a role in ocd, at least in some subtypes of this disorder. |
2005-06-24 |
2023-08-12 |
rat |
| José R Pineda, Josep M Canals, Miquel Bosch, Albert Adell, Guadalupe Mengod, Francesc Artigas, Patrik Ernfors, Jordi Alberc. Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease. Journal of neurochemistry. vol 93. issue 5. 2005-06-24. PMID:15934928. |
in addition, reduction of bdnf expression exacerbates the dopaminergic neuronal dysfunction seen in mutant huntingtin mice, such as the decrease in retrograde labelling of dopaminergic neurons and striatal dopamine content. |
2005-06-24 |
2023-08-12 |
mouse |
| Rael D Strou. Dehydroepiandrosterone (DHEA) augmentation in the management of schizophrenia symptomatology. Essential psychopharmacology. vol 6. issue 3. 2005-06-23. PMID:15869021. |
in the author's study, administering dhea to patients with schizophrenia who had moderate to severe negative symptoms and who were maintained on antipsychotic medications induced significant improvement, more so in women and corresponding to increased plasma levels of dhea and dhea-s. possible mechanisms of action include enhanced dopamine release, enhanced responsiveness at the n-methyl d-aspartate (nmda) receptor, facilitation of sigma receptor activity, selective potentiation of dopaminergic neurotransmission, and a general anxiolytic action. |
2005-06-23 |
2023-08-12 |
Not clear |
| Raka Jain, Stephen G Holtzma. Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists. Brain research bulletin. vol 65. issue 5. 2005-06-17. PMID:15833596. |
the purpose of this study was to determine if caffeine induces cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic drugs that act through distinct mechanisms (e.g., release, uptake inhibition, direct activation of dopamine d(1)- or d(2)-family receptors). |
2005-06-17 |
2023-08-12 |
rat |
| Raka Jain, Stephen G Holtzma. Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists. Brain research bulletin. vol 65. issue 5. 2005-06-17. PMID:15833596. |
thus, caffeine produces differential cross tolerance to the amphetamine-like discriminative effects of dopaminergic drugs, a phenomenon in which the dopamine d(1) receptor appears to have an important role. |
2005-06-17 |
2023-08-12 |
rat |
| Jannine G Truong, Glen R Hanson, Annette E Fleckenstei. Apomorphine increases vesicular monoamine transporter-2 function: implications for neurodegeneration. European journal of pharmacology. vol 492. issue 2-3. 2005-06-14. PMID:15178358. |
apomorphine is a nonselective dopamine d1/d2 receptor agonist used in europe to treat symptoms resulting from the dopaminergic degeneration associated with parkinson's disease. |
2005-06-14 |
2023-08-12 |
rat |
| Ryszard Przewlock. Opioid abuse and brain gene expression. European journal of pharmacology. vol 500. issue 1-3. 2005-06-14. PMID:15464044. |
neuronal basis of positive reinforcement, which is essential to the action of opioids, relies on activation of dopaminergic neurons resulting in an increased dopamine release in the mesolimbic brain structures. |
2005-06-14 |
2023-08-12 |
Not clear |
| Anissa Abi-Dargham, Marc Laruell. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. European psychiatry : the journal of the Association of European Psychiatrists. vol 20. issue 1. 2005-06-14. PMID:15642439. |
multiple lines of evidence including recent imaging studies suggest that schizophrenia is associated with an imbalance of the dopaminergic system, entailing hyperstimulation of striatal dopamine (da) d2 receptors and understimulation of cortical da d1 receptors. |
2005-06-14 |
2023-08-12 |
Not clear |
| Alfred Heller, Lisa Won, Nancy Bubula, Suzanne Hessefort, Josh W Kurutz, Giridher A Reddy, Martin Gros. Long-chain fatty acids increase cellular dopamine in an immortalized cell line (MN9D) derived from mouse mesencephalon. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694270. |
the lysate of an immortalized monoclonal cell line derived from the striatum (x61) contains a dopaminergic stimulatory activity that is capable of increasing the dopamine content of an immortalized mouse mesencephalic cell line (mn9d) which expresses a dopaminergic phenotype. |
2005-06-14 |
2023-08-12 |
mouse |
| Alfred Heller, Lisa Won, Nancy Bubula, Suzanne Hessefort, Josh W Kurutz, Giridher A Reddy, Martin Gros. Long-chain fatty acids increase cellular dopamine in an immortalized cell line (MN9D) derived from mouse mesencephalon. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694270. |
mn9d dopamine increases linearly over a 48 h period suggesting the induction of an increased dopaminergic phenotype in these dividing cells. |
2005-06-14 |
2023-08-12 |
mouse |