| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sylvia M Boesch, Eveline Donnemiller, Jörg Müller, Klaus Seppi, Helga Weirich-Schwaiger, Werner Poewe, Gregor K Wennin. Abnormalities of dopaminergic neurotransmission in SCA2: a combined 123I-betaCIT and 123I-IBZM SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 11. 2005-02-14. PMID:15390003. |
we conclude that dopaminergic neurotransmission is impaired in the ataxic presentation of sca2, with a prominent loss of striatal dopamine transporter function. |
2005-02-14 |
2023-08-12 |
human |
| Mei Gu, M M Iravani, M Irvani, J Mark Cooper, Diane King, Peter Jenner, Anthony H V Schapir. Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms. Journal of neurochemistry. vol 91. issue 5. 2005-02-10. PMID:15569251. |
we have investigated the ability of pramipexole, a dopamine agonist used in the symptomatic treatment of parkinson's disease (pd), to protect against cell death induced by 1-methyl-4-phenylpyridinium (mpp+) and rotenone in dopaminergic and non-dopaminergic cells. |
2005-02-10 |
2023-08-12 |
Not clear |
| Karen S Rommelfanger, David Weinshenker, Gary W Mille. Reduced MPTP toxicity in noradrenaline transporter knockout mice. Journal of neurochemistry. vol 91. issue 5. 2005-02-10. PMID:15569255. |
neurotoxin ablation of the lc noradrenergic neurons has been shown to exacerbate the dopaminergic toxicity of mptp, suggesting that the noradrenergic system protects dopamine neurons. |
2005-02-10 |
2023-08-12 |
mouse |
| Karen S Rommelfanger, David Weinshenker, Gary W Mille. Reduced MPTP toxicity in noradrenaline transporter knockout mice. Journal of neurochemistry. vol 91. issue 5. 2005-02-10. PMID:15569255. |
net ko and wild-type littermates were administered mptp and striatal dopamine terminal integrity was assessed by hplc of monoamines, immmunoblotting for dopaminergic markers and tyrosine hydroxylase (th) immunohistochemistry. |
2005-02-10 |
2023-08-12 |
mouse |
| Marsha S A Smith, Marian L Evat. Movement disorders in pregnancy. Neurologic clinics. vol 22. issue 4. 2005-02-08. PMID:15474767. |
regarding the use of dopaminergic agents, the dopamine agonist, pergolide, can be maintained during pregnancy for the treatment of pd, segawa disease, and rls. |
2005-02-08 |
2023-08-12 |
Not clear |
| Masato Asanuma, Ikuko Miyazaki, Francisco J Diaz-Corrales, Norio Ogaw. Quinone formation as dopaminergic neuron-specific oxidative stress in the pathogenesis of sporadic Parkinson's disease and neurotoxin-induced parkinsonism. Acta medica Okayama. vol 58. issue 5. 2005-02-08. PMID:15666991. |
recently, the neurotoxicity of dopamine quinone formation by auto-oxidation of dopamine has been shown to cause specific cell death of dopaminergic neurons in the pathogenesis of sporadic pd and dopaminergic neurotoxin-induced parkinsonism. |
2005-02-08 |
2023-08-12 |
Not clear |
| Masato Asanuma, Ikuko Miyazaki, Francisco J Diaz-Corrales, Norio Ogaw. Quinone formation as dopaminergic neuron-specific oxidative stress in the pathogenesis of sporadic Parkinson's disease and neurotoxin-induced parkinsonism. Acta medica Okayama. vol 58. issue 5. 2005-02-08. PMID:15666991. |
in this article, we mainly review recent studies on the neurotoxicity of quinone formation as a dopaminergic neuron-specific oxidative stress and its role in the etiology of pd, in addition to several neuroprotective approaches against dopamine quinone-induced toxicity. |
2005-02-08 |
2023-08-12 |
Not clear |
| Bankole A Johnso. Progress in the development of topiramate for treating alcohol dependence: from a hypothesis to a proof-of-concept study. Alcoholism, clinical and experimental research. vol 28. issue 8. 2005-02-04. PMID:15318111. |
because corticomesolimbic dopamine neurons interact with a variety of neurotransmitters that modulate its effects in the nucleus accumbens, it might be possible to more reliably control these dopaminergic effects with a medication that acted contemporaneously on more than one neuromodulator of dopamine function. |
2005-02-04 |
2023-08-12 |
Not clear |
| Trent J Volz, James O Schen. L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism. Synapse (New York, N.Y.). vol 54. issue 3. 2005-01-31. PMID:15452864. |
literature reports suggest that nitric oxide (no) participates in the regulation of dopaminergic neurotransmission, possibly through interaction with cysteine residues of the dopamine transporter (dat). |
2005-01-31 |
2023-08-12 |
rat |
| H P Ludi. [Are there innovations in the treatment of Parkinson's disease?]. Praxis. vol 93. issue 45. 2005-01-31. PMID:15571301. |
in the group of medication acting on the dopaminergic system the transdermal application of a dopamine agonist (rotigotine) and a new mao b inhibitor (rasigiline) are receiving most attention. |
2005-01-31 |
2023-08-12 |
Not clear |
| A Storch, A C Ludolph, J Schwar. Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 10-11. 2005-01-26. PMID:15480838. |
dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration. |
2005-01-26 |
2023-08-12 |
Not clear |
| Xingchao Geng, Liangwen Song, Xiaoping Pu, Pengfei T. Neuroprotective effects of phenylethanoid glycosides from Cistanches salsa against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice. Biological & pharmaceutical bulletin. vol 27. issue 6. 2005-01-25. PMID:15187420. |
the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) has been employed to create a parkinson's disease-like model in both rodents and primates based primarily on its ability to create a striatal dopamine deficit due to the loss of dopaminergic neurons in the substantia nigra compacta. |
2005-01-25 |
2023-08-12 |
mouse |
| Xingchao Geng, Liangwen Song, Xiaoping Pu, Pengfei T. Neuroprotective effects of phenylethanoid glycosides from Cistanches salsa against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice. Biological & pharmaceutical bulletin. vol 27. issue 6. 2005-01-25. PMID:15187420. |
the present in vivo data clearly demonstrate that phgs can protect dopaminergic neurons against dopamine neurotoxicity induced by mptp, as suggested by an earlier in vitro study. |
2005-01-25 |
2023-08-12 |
mouse |
| Lixin Zhang, Anita Fletcher-Turner, Mark A Marchionni, Subbu Apparsundaram, Kerstin H Lundgren, David M Yurek, Kim B Seroog. Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. Journal of neurochemistry. vol 91. issue 6. 2005-01-21. PMID:15584912. |
because midbrain dopamine (da) cells express the nrg receptor, erbb4, the present study examined the potential neurotrophic and/or neuroprotective effects of ggf2 on cultured primary dopaminergic neurons. |
2005-01-21 |
2023-08-12 |
rat |
| Marina E Embor. Evaluation of animal models of Parkinson's disease for neuroprotective strategies. Journal of neuroscience methods. vol 139. issue 2. 2005-01-19. PMID:15488225. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic nigral neurons and striatal dopamine. |
2005-01-19 |
2023-08-12 |
Not clear |
| Manik Pullagurla, Tatiana Bondareva, Richard Young, Richard A Glenno. Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245. Pharmacology, biochemistry, and behavior. vol 78. issue 2. 2005-01-18. PMID:15219766. |
5-ht(6) serotonin receptors are distributed within some dopamine terminal regions in the brain leading to suggestions that they might influence dopaminergic function. |
2005-01-18 |
2023-08-12 |
rat |
| Christophe Lo Bianco, Bernard L Schneider, Matthias Bauer, Ali Sajadi, Alexis Brice, Takeshi Iwatsubo, Patrick Aebische. Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 50. 2005-01-14. PMID:15576511. |
the loss of parkin's e3-ligase activity leads to dopaminergic neuronal degeneration in early-onset autosomal recessive juvenile parkinsonism, suggesting a key role of parkin for dopamine neuron survival. |
2005-01-14 |
2023-08-12 |
human |
| Adrienn Filla, L Hiripi, K Eleke. Serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of Lymnaea stagnalis L. Acta biologica Hungarica. vol 55. issue 1-4. 2005-01-13. PMID:15270248. |
serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of lymnaea stagnalis l. the role of the dopaminergic and serotonergic system was studied during the embryonic development of the pond snail lymnaea stagnalis, with special attention to the effect of dopamine and serotonin as well as their agonists and antagonists on the rotation of the veliger larvae, and to the effect of precursors and inhibitors of the synthetizing enzymes on the duration of the embryonic life. |
2005-01-13 |
2023-08-12 |
Not clear |
| Adrienn Filla, L Hiripi, K Eleke. Serotonergic and dopaminergic influence of the duration of embryogenesis and intracapsular locomotion of Lymnaea stagnalis L. Acta biologica Hungarica. vol 55. issue 1-4. 2005-01-13. PMID:15270248. |
dopaminergic agonists accelerated the rotation by 62% to 233%, and their effect was ranged as follows: dopamine > apomorphine > m-tyramine approximately equal to p-tyramine. |
2005-01-13 |
2023-08-12 |
Not clear |
| Emily M Jutkiewicz, Jack Bergma. Effects of dopamine D1 ligands on eye blinking in monkeys: efficacy, antagonism, and D1/D2 interactions. The Journal of pharmacology and experimental therapeutics. vol 311. issue 3. 2005-01-13. PMID:15292458. |
overall, eye blink rate appears to be a robust behavioral measure that can be used to measure changes in dopaminergic d1 signaling and as a functional assay of agonist efficacy at dopamine d1 receptors. |
2005-01-13 |
2023-08-12 |
monkey |