| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paola Devoto, Giovanna Flore, Pierluigi Saba, M Paola Castelli, A Paola Piras, William Luesu, M Cristina Viaggi, M Grazia Ennas, Gian Luigi Gess. 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex. Journal of neuroscience research. vol 86. issue 7. 2008-07-08. PMID:18189323. |
the unilateral injury of dopaminergic neurons, by 6-hydroxydopamine injection in the ventral tegmental area, dramatically reduced the immunoreactivity for dopamine transporter in the cerebral hemisphere ipsilateral to the lesion. |
2008-07-08 |
2023-08-12 |
rat |
| Steve Shoptaw, Keith G Heinzerling, Erin Rotheram-Fuller, Uyen H Kao, Pin-Chieh Wang, Michelle A Bholat, Walter Lin. Bupropion hydrochloride versus placebo, in combination with cognitive behavioral therapy, for the treatment of cocaine abuse/dependence. Journal of addictive diseases. vol 27. issue 1. 2008-07-08. PMID:18551884. |
bupropion hydrochloride is a dopamine and norepinephrine reuptake inhibitor which may be an effective treatment for cocaine dependence due to its ability to reverse deficits in dopaminergic functioning that occur in chronic cocaine users. |
2008-07-08 |
2023-08-12 |
Not clear |
| Szu-Chia Lai, Rou-Shayn Che. [Restless legs syndrome]. Acta neurologica Taiwanica. vol 17. issue 1. 2008-07-08. PMID:18564830. |
dopaminergic stimulation with levodopa or dopamine agonists is the first choice in idiopathic restless legs syndrome, but the long-term adverse effect of augmentation should be carefully monitored. |
2008-07-08 |
2023-08-12 |
Not clear |
| Philip A Robinso. Protein stability and aggregation in Parkinson's disease. The Biochemical journal. vol 413. issue 1. 2008-07-03. PMID:18537793. |
the reason that dopaminergic neurons are particularly sensitive may be due to the additional cellular stress caused by the breakdown of the inherently chemically unstable neurotransmitter, dopamine. |
2008-07-03 |
2023-08-12 |
Not clear |
| Mona Seif-El-Nasr, Amina S Atia, Rania M Abdelsala. Effect of MAO-B inhibition against ischemia-induced oxidative stress in the rat brain. Comparison with a rational antioxidant. Arzneimittel-Forschung. vol 58. issue 4. 2008-07-02. PMID:18540477. |
these results indicate that deprenyl protected the rat brains against the ischemia-induced oxidative damage, an effect which might be explained through multiple mechanisms, possibly due to reduction of dopamine catabolism with a subsequent increased activity on dopaminergic d2 receptors and suppressing the action of ros as well. |
2008-07-02 |
2023-08-12 |
rat |
| R Anckarsäter, H Zetterberg, J-E Månsson, K Blennow, H Anckarsäte. Non-neurological surgery results in a neurochemical stress response. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18250956. |
the csf concentrations of the dopamine metabolite homovanillinic acid (hva) and the serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa), which are related to the activity of the dopaminergic and serotonergic systems of the brain, increased sharply during surgery and reached 188% and 166% of their initial concentrations on the morning after the intervention (p < 0.0001). |
2008-07-01 |
2023-08-12 |
human |
| Tetsuya Maeda, Ken Nagata, Yasuji Yoshid. Exogenous l-DOPA induce no dopamine immuno-reactivity in striatal astroglias and microglias of adult rats with extensive nigro-striatal dopaminergic denervation. Neuroscience letters. vol 433. issue 3. 2008-06-30. PMID:18255227. |
exogenous l-dopa induce no dopamine immuno-reactivity in striatal astroglias and microglias of adult rats with extensive nigro-striatal dopaminergic denervation. |
2008-06-30 |
2023-08-12 |
rat |
| Tetsuya Maeda, Ken Nagata, Yasuji Yoshid. Exogenous l-DOPA induce no dopamine immuno-reactivity in striatal astroglias and microglias of adult rats with extensive nigro-striatal dopaminergic denervation. Neuroscience letters. vol 433. issue 3. 2008-06-30. PMID:18255227. |
the aim of this study was to determine whether striatal glial cells of adult rats with extensive nigro-striatal dopaminergic denervation are induced to contain dopamine by injection of exogenous l-dopa. |
2008-06-30 |
2023-08-12 |
rat |
| Dallas R Donohoe, Kathrine Weeks, Eric J Aamodt, Donard S Dwye. Antipsychotic drugs alter neuronal development including ALM neuroblast migration and PLM axonal outgrowth in Caenorhabditis elegans. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 26. issue 3-4. 2008-06-30. PMID:18282677. |
although the antipsychotic drugs are potent antagonists of dopamine and serotonin receptors, the neurodevelopmental deficits were not rescued by co-incubation with serotonin or the dopaminergic agonist, quinpirole. |
2008-06-30 |
2023-08-12 |
rat |
| Tong Liu, Laurence Dartevelle, Chunyan Yuan, Hongping Wei, Ying Wang, Jean-François Ferveur, Aike Gu. Increased dopamine level enhances male-male courtship in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 21. 2008-06-26. PMID:18495888. |
we used genetic and pharmacological approaches to manipulate the dopamine level in dopaminergic cells in drosophila and investigated the consequence of this manipulation on male-male courtship behavior. |
2008-06-26 |
2023-08-12 |
drosophila_melanogaster |
| Julie C Healey, Danny G Winder, Thomas L Kas. Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions. Alcohol (Fayetteville, N.Y.). vol 42. issue 3. 2008-06-23. PMID:18358675. |
using a chronic inhalation model of ethanol exposure in mice, we have begun to investigate the effects of alcohol intake on dopaminergic signaling by examining protein levels of tyrosine hydroxylase and the dopamine transporter, as well as monoamine metabolites in three different target fields of three different dopaminergic nuclei. |
2008-06-23 |
2023-08-12 |
mouse |
| Julie C Healey, Danny G Winder, Thomas L Kas. Chronic ethanol exposure leads to divergent control of dopaminergic synapses in distinct target regions. Alcohol (Fayetteville, N.Y.). vol 42. issue 3. 2008-06-23. PMID:18358675. |
we have focused on the dorsal lateral bed nucleus of the stria terminalis because of the reported involvement of dorsal lateral bed nucleus of the stria terminalis dopamine in ethanol intake, and the nucleus accumbens and dorsal striatum because of their dense dopaminergic innervation. |
2008-06-23 |
2023-08-12 |
mouse |
| J Stuginski-Barbosa, G G R Rodrigues, M E Bigal, J G Special. Burning mouth syndrome responsive to pramipexol. The journal of headache and pain. vol 9. issue 1. 2008-06-20. PMID:18219443. |
herein we report one case of primary disabling bms, previously refractory to multiple regimens, with complete and persistent improvement with pramipexol, a nonergot dopamine agonist which has high selectivity for dopaminergic d2 receptors. |
2008-06-20 |
2023-08-12 |
Not clear |
| M A Cenci, H S Lindgre. Advances in understanding L-DOPA-induced dyskinesia. Current opinion in neurobiology. vol 17. issue 6. 2008-06-20. PMID:18308560. |
the crucial role of dopamine (da) in movement control is illustrated by the spectrum of motor disorders caused by either a deficiency or a hyperactivity of dopaminergic transmission in the basal ganglia. |
2008-06-20 |
2023-08-12 |
Not clear |
| Stewart A Facto. Current status of symptomatic medical therapy in Parkinson's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 5. issue 2. 2008-06-20. PMID:18394561. |
for 40 years, these therapies have been primarily dopaminergic, and currently include the dopamine (da) precursor levodopa (ld), da agonists, catechol-o-methyltransferase (comt) inhibitors, and monoamine oxidase (mao) inhibitors. |
2008-06-20 |
2023-08-12 |
Not clear |
| Sebastian A Andujar, Biagina Migliore de Angel, Jaime E Charris, Anita Israel, Heberto Suárez-Roca, Simon E López, Maria R Garrido, Elvia Victoria Cabrera, Gonzalo Visbal, Cecire Rosales, Fernando D Suvire, Ricardo D Enriz, Jorge E Angel-Guí. Synthesis, dopaminergic profile, and molecular dynamics calculations of N-aralkyl substituted 2-aminoindans. Bioorganic & medicinal chemistry. vol 16. issue 6. 2008-06-13. PMID:18166467. |
the aim of the present study was to synthesize n-[2-(4,5-dihydroxyphenyl)-methyl-ethyl]-4,5-dihydroxy-2-aminoindan hydrobromide (3), planned to be a dopamine ligand, and to evaluate its dopaminergic action profile. |
2008-06-13 |
2023-08-12 |
rat |
| Rajendra D Badgaiyan, Alan J Fischman, Nathaniel M Alper. Explicit motor memory activates the striatal dopamine system. Neuroreport. vol 19. issue 4. 2008-06-13. PMID:18287937. |
as we have earlier observed dopamine release in all of these areas, except the right putamen, in an implicit motor memory task, it seems that the striatal dopaminergic network for implicit and explicit motor memories are essentially similar. |
2008-06-13 |
2023-08-12 |
human |
| Danyang Liu, Durk Dijkstra, Jan B de Vries, Håkan V Wikströ. A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol. Bioorganic & medicinal chemistry. vol 16. issue 6. 2008-06-13. PMID:18313303. |
previously, we have demonstrated that enone prodrugs of dopaminergic catecholamines represent a new type of dopamine (da) agonist. |
2008-06-13 |
2023-08-12 |
Not clear |
| Bin Liu, Jun Xia Xie, Lai Ling Tsang, Dewi Kenneth Rowlands, Lok Sze Ho, Yu Lin Gou, Yiu Wa Chung, Hsiao Chang Cha. Bak Foong protects dopaminergic neurons against MPTP-induced neurotoxicity by its anti-apoptotic activity. Cell biology international. vol 32. issue 1. 2008-06-12. PMID:17920944. |
in the present study, we have investigated the possible neuroprotective action of bfp upon the nigrostriatal dopaminergic system by examining its effect on the expression patterns of tyrosine hydroxylase (th) and dopamine transporter (dat) in the 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine (mptp)-induced parkinson's disease (pd) mouse model. |
2008-06-12 |
2023-08-12 |
mouse |
| Xiomara A Perez, Neeraja Parameswaran, Luping Z Huang, Kathryn T O'Leary, Maryka Qui. Pre-synaptic dopaminergic compensation after moderate nigrostriatal damage in non-human primates. Journal of neurochemistry. vol 105. issue 5. 2008-06-12. PMID:18248617. |
despite a dramatic loss of nigrostriatal dopaminergic neurons in parkinson's disease, clinical symptoms only arise with 70-80% reduction of striatal dopamine. |
2008-06-12 |
2023-08-12 |
monkey |