| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Exley, S J Crag. Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18037926. |
we will review the powerful filtering by nachrs of striatal dopamine release and discuss its dependence on activity in dopaminergic and cholinergic neurons. |
2008-04-28 |
2023-08-12 |
Not clear |
| Jayanth S Chandran, Xian Lin, Agustin Zapata, Ahmet Höke, Mika Shimoji, Shonagh O'Leary Moore, Matthew P Galloway, Fiona M Laird, Philip C Wong, Donald L Price, Kathleen R Bailey, Jacqueline N Crawley, Toni Shippenberg, Huaibin Ca. Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18187333. |
the basal level of extracellular dopamine, evoked dopamine release and dopamine receptor d2 sensitivity appeared normal in the striatum of dj-1(-/-) mice, which was consistent with similar results between dj-1(-/-) and controls in behavioral paradigms specific for the dopaminergic system. |
2008-04-28 |
2023-08-12 |
mouse |
| B Galan-Rodriguez, A del-Marco, J A Flores, S Ramiro-Fuentes, R Gonzalez-Aparicio, I Tunez, I Tasset, E Fernandez-Espej. Grafts of extra-adrenal chromaffin cells as aggregates show better survival rate and regenerative effects on parkinsonian rats than dispersed cell grafts. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18206378. |
sprouting of spared dopaminergic fibers within the striatum, reduction of dopamine axon degeneration, and/or enhanced phenotypic expression of th would explain striatal regeneration. |
2008-04-28 |
2023-08-12 |
rat |
| Victor S Van Laar, April A Dukes, Michael Cascio, Teresa G Hasting. Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18226537. |
we have previously shown that dopamine oxidation leads to selective dopaminergic terminal degeneration in vivo and alters mitochondrial function in vitro. |
2008-04-28 |
2023-08-12 |
rat |
| Dieter Scheller, Christine Stichel-Gunkel, Hermann Lübbert, Gregory Porras, Paula Ravenscroft, Michael Hill, Erwan Bezar. Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease. Neuroscience letters. vol 432. issue 1. 2008-04-24. PMID:18162314. |
the study was designed to assess the neuroprotective potential of the d(3)/d(2)/d(1) dopamine receptor agonist rotigotine in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned (mptp) mouse model of parkinson's disease by measuring mesencephalic degenerating neurons using fluorojade staining and the remaining dopaminergic nerve endings in the striatum using dopamine transporter binding. |
2008-04-24 |
2023-08-12 |
mouse |
| Philippe Huot, Martin Lévesque, Marc Morissette, Frédéric Calon, Mehdi Dridi, Thérèse Di Paolo, André Paren. L-Dopa treatment abolishes the numerical increase in striatal dopaminergic neurons in parkinsonian monkeys. Journal of chemical neuroanatomy. vol 35. issue 1. 2008-04-22. PMID:17706922. |
the striatum harbors a population of dopaminergic interneurons that increases in number in animal models of parkinson's disease (pd), presumably to compensate for dopamine (da) depletion. |
2008-04-22 |
2023-08-12 |
monkey |
| Edward C Stack, Joellyn L Ferro, Jinho Kim, Steven J Del Signore, Sarah Goodrich, Samantha Matson, Bonnie B Hunt, Kerry Cormier, Karen Smith, Wayne R Matson, Hoon Ryu, Robert J Ferrant. Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease. Biochimica et biophysica acta. vol 1782. issue 3. 2008-04-22. PMID:18206128. |
the neuroprotective effects of cystamine treatment significantly ameliorated nigral neuronal loss, preserved striatal dopaminergic projections, and improved striatal dopamine and metabolite levels, as compared to mptp alone. |
2008-04-22 |
2023-08-12 |
human |
| Oliver D Howes, Andrew J Montgomery, Marie-Claude Asselin, Robin M Murray, Paul M Grasby, Philip K McGuir. Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis. The British journal of psychiatry. Supplement. vol 51. 2008-04-21. PMID:18055930. |
these studies support the predictions of the dopamine hypothesis, but it remains to be determined whether dopaminergic abnormalities pre-date or are secondary to the development of psychosis. |
2008-04-21 |
2023-08-12 |
Not clear |
| Jean-Paul Selten, Elizabeth Cantor-Graa. Hypothesis: social defeat is a risk factor for schizophrenia? The British journal of psychiatry. Supplement. vol 51. 2008-04-21. PMID:18055945. |
experiments with rodents have shown that social defeat leads to dopaminergic hyperactivity and to behavioural sensitisation, whereby the animal displays an enhanced behavioural and dopamine response to dopamine agonists. |
2008-04-21 |
2023-08-12 |
Not clear |
| BomBi Lee, Chae Ha Yang, Dae-Hyun Hahm, Hye-Jung Lee, Seung-Moo Han, Kyung-Soo Kim, Insop Shi. Inhibitory effects of ginseng total saponins on behavioral sensitization and dopamine release induced by cocaine. Biological & pharmaceutical bulletin. vol 31. issue 3. 2008-04-21. PMID:18310906. |
it has been shown that repeated injections of cocaine produce an increase in locomotor activity, the expression of the immediate-early gene, c-fos, and the release of dopamine (da) in the nucleus accumbens (nac), which is one of the main dopaminergic terminal areas. |
2008-04-21 |
2023-08-12 |
rat |
| A Carmona, G Devès, R Orteg. Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques. Analytical and bioanalytical chemistry. vol 390. issue 6. 2008-04-18. PMID:18246461. |
we found that the iron content increases in dopaminergic cells exposed to an excess iron, with marked accumulation within distal ends, suggesting interaction between iron and dopamine within neurotransmitter vesicles. |
2008-04-18 |
2023-08-12 |
Not clear |
| Jon Stoess. Potential therapeutic targets for Parkinson's disease. Expert opinion on therapeutic targets. vol 12. issue 4. 2008-04-17. PMID:18348679. |
these include features of disease that are probably not related to dopamine deficiency and are unresponsive to dopamine-replacement therapy, as well as complications of long-term dopaminergic therapy itself. |
2008-04-17 |
2023-08-12 |
human |
| C M Leite, R E Szawka, J A Anselmo-Franc. Alpha-oestrogen and progestin receptor expression in the hypothalamus and preoptic area dopaminergic neurones during oestrous in cycling rats. Journal of neuroendocrinology. vol 20. issue 1. 2008-04-16. PMID:18081559. |
because prolactin release is tonically inhibited by hypothalamic dopamine and modulated by dopamine transmission in the preoptic area (poa), the present study aimed to evaluate whether oestrogen receptor (er)-alpha and progestin receptor (pr) expression in the dopaminergic neurones of arcuate (arc), periventricular, anteroventral periventricular (avpe) and ventromedial preoptic (vmpo) nuclei changes during the day of oestrous. |
2008-04-16 |
2023-08-12 |
rat |
| Ali Salahpour, Amy J Ramsey, Ivan O Medvedev, Brian Kile, Tatyana D Sotnikova, Ericka Holmstrand, Valentina Ghisi, Peter J Nicholls, Ling Wong, Karen Murphy, Susan R Sesack, R Mark Wightman, Raul R Gainetdinov, Marc G Caro. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 11. 2008-04-15. PMID:18347339. |
the dopamine transporter (dat) plays a key role in the regulation of dopaminergic signaling wherein it controls both the spatial and temporal actions of dopamine. |
2008-04-15 |
2023-08-12 |
mouse |
| R Laguna Goya, P Tyers, R A Barke. The search for a curative cell therapy in Parkinson's disease. Journal of the neurological sciences. vol 265. issue 1-2. 2008-04-11. PMID:17936303. |
parkinson's disease (pd) is a neurodegenerative disorder, characterised by the progressive loss of dopaminergic neurons in the substantia nigra, and typically treated by dopamine replacement. |
2008-04-11 |
2023-08-12 |
human |
| Masato Asanuma, Ikuko Miyazaki, Francisco J Diaz-Corrales, Ko Miyoshi, Norio Ogawa, Miho Murat. Preventing effects of a novel anti-parkinsonian agent zonisamide on dopamine quinone formation. Neuroscience research. vol 60. issue 1. 2008-04-11. PMID:18022268. |
the neurotoxicity of dopamine (da) quinones as dopaminergic neuron-specific oxidative stress is considered to play a role in the pathogenesis and/or progression of parkinson's disease (pd), since da quinones conjugate with several key pd pathogenic molecules (e.g., tyrosine hydroxylase, alpha-synuclein and parkin) to form protein-bound quinone (quinoprotein) and consequently inhibit their functions. |
2008-04-11 |
2023-08-12 |
Not clear |
| M A de Souza Silva, B Topic, J P Huston, C Matter. Intranasal dopamine application increases dopaminergic activity in the neostriatum and nucleus accumbens and enhances motor activity in the open field. Synapse (New York, N.Y.). vol 62. issue 3. 2008-04-11. PMID:18081176. |
intranasal dopamine application increases dopaminergic activity in the neostriatum and nucleus accumbens and enhances motor activity in the open field. |
2008-04-11 |
2023-08-12 |
rat |
| Shaik Shavali, Donald A Sen. Synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma SH-SY5Y cells. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:18079140. |
synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma sh-sy5y cells. |
2008-04-10 |
2023-08-12 |
human |
| Shaik Shavali, Donald A Sen. Synergistic neurotoxic effects of arsenic and dopamine in human dopaminergic neuroblastoma SH-SY5Y cells. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:18079140. |
the initial goal of the present study was to determine if a mixture of arsenite (as(+3)) and dopamine (da) could cause enhanced degeneration of dopaminergic neuronal cells. |
2008-04-10 |
2023-08-12 |
human |
| Yoko Hirata, Hiromi Suzuno, Tadamiki Tsuruta, Kentaro Oh-hashi, Kazutoshi Kiuch. The role of dopamine transporter in selective toxicity of manganese and rotenone. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18206288. |
the dopamine transporter has been shown to be the most relevant target site for the specificity of 1-methyl-4-phenylpyridinium ion (mpp+), a neurotoxin for dopaminergic neurons. |
2008-04-09 |
2023-08-12 |
Not clear |