| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoko Hirata, Hiromi Suzuno, Tadamiki Tsuruta, Kentaro Oh-hashi, Kazutoshi Kiuch. The role of dopamine transporter in selective toxicity of manganese and rotenone. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18206288. |
the dopamine transporter has been shown to be the most relevant target site for the specificity of 1-methyl-4-phenylpyridinium ion (mpp+), a neurotoxin for dopaminergic neurons. |
2008-04-09 |
2023-08-12 |
Not clear |
| Yoko Hirata, Hiromi Suzuno, Tadamiki Tsuruta, Kentaro Oh-hashi, Kazutoshi Kiuch. The role of dopamine transporter in selective toxicity of manganese and rotenone. Toxicology. vol 244. issue 2-3. 2008-04-09. PMID:18206288. |
the aim of this study was to determine the cellular mechanisms of manganese or rotenone uptake in dopaminergic cells via the dopamine transporter. |
2008-04-09 |
2023-08-12 |
Not clear |
| Oscar Arias-Carrión, Ernst Pŏppe. Dopamine, learning, and reward-seeking behavior. Acta neurobiologiae experimentalis. vol 67. issue 4. 2008-04-09. PMID:18320725. |
dopaminergic neurons of the midbrain are the main source of dopamine (da) in the brain. |
2008-04-09 |
2023-08-12 |
Not clear |
| Stephan Lammel, Andrea Hetzel, Olga Häckel, Ian Jones, Birgit Liss, Jochen Roepe. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron. vol 57. issue 5. 2008-04-08. PMID:18341995. |
among this dual dopamine midbrain system defined in this study by converging anatomical, electrophysiological, and molecular properties, mesoprefrontal dopaminergic neurons are unique, as only they do not possess functional somatodendritic girk2-coupled dopamine d2 autoreceptors. |
2008-04-08 |
2023-08-12 |
Not clear |
| Tetsuya Suhara, Michie Miyosh. [Distribution and function of dopamine D1, D2 receptor]. Rinsho shinkeigaku = Clinical neurology. vol 47. issue 11. 2008-04-04. PMID:18210808. |
since dopamine is an important molecule for pathophysiology of parkinson's disease and schizophrenia, we reviewed in vivo imaging studies focusing on dopaminergic transmission. |
2008-04-04 |
2023-08-12 |
human |
| Nobukatsu Sawamot. [Functional mapping of dopaminergic transmission]. Rinsho shinkeigaku = Clinical neurology. vol 47. issue 11. 2008-04-04. PMID:18210810. |
d2 receptor antagonist 11c-raclopride (rac) with positron emission tomography (pet) now provides an in vivo approach for investigating dopaminergic transmission by monitoring changes in synaptic dopamine levels during task performance, our rac pet study suggests that the capacity to release dopamine during a working memory task is impaired in the striatum but relatively preserved in the medial prefrontal cortex in patients with pd. |
2008-04-04 |
2023-08-12 |
Not clear |
| Jing-Jer Ke, Hsiun-Ing Chen, Chauying J Jen, Yu-Min Kuo, Chianfang G Cherng, Yen-Ping N Tsai, Ming-Che Ho, Chia-Wen Tsai, Lung Y. Mutual enhancement of central neurotoxicity induced by ketamine followed by methamphetamine. Toxicology and applied pharmacology. vol 227. issue 2. 2008-03-31. PMID:18076959. |
however, pretreatment with repeated doses of ketamine aggravated methamphetamine-induced dopaminergic terminal loss as evidenced by a drastic decrease in the levels of dopamine, 3,4-dihydroxyphenylacetic acid, and dopamine transporter density as well as poor gait balance performance. |
2008-03-31 |
2023-08-12 |
mouse |
| H Zhu, S Clemens, M Sawchuk, S Hochma. Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: a real-time polymerase chain reaction and non-autoradiographic in situ hybridization study. Neuroscience. vol 149. issue 4. 2008-03-28. PMID:17936519. |
dopaminergic modulatory actions are implicated in sensory, motor and autonomic functions in the spinal cord but the expression properties of the different dopamine receptors in the spinal cord remain incomplete. |
2008-03-28 |
2023-08-12 |
mouse |
| H Zhu, S Clemens, M Sawchuk, S Hochma. Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: a real-time polymerase chain reaction and non-autoradiographic in situ hybridization study. Neuroscience. vol 149. issue 4. 2008-03-28. PMID:17936519. |
we conclude that the expression and extensive postsynaptic distribution of all known dopamine receptors in spinal cord correspond well with the broad descending dopaminergic projection territory supporting a widespread dopaminergic control over spinal neuronal systems. |
2008-03-28 |
2023-08-12 |
mouse |
| D Rodaros, D A Caruana, S Amir, J Stewar. Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area. Neuroscience. vol 150. issue 1. 2008-03-28. PMID:17961928. |
crf is released in the ventral tegmental area (vta), the cell body region of the mesocorticolimbic dopaminergic neurons, in response to acute stress and plays a role in stress-activation of appetitive behavior [wang b, shaham y, zitzman d, azari s, wise ra, you zb (2005) cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
an abnormal accumulation of cytosolic dopamine resulting in reactive oxygen species and dopamine-quinone products may play an important role in the rather selective degeneration of substantia nigra pars compacta (snc) dopaminergic neurons in parkinson's disease. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
the neuronal-specific vesicular monoamine transporter (vmat2), responsible for uptake of dopamine into vesicles, has been shown to play a central role both in intracellular dopamine homeostasis and sequestration of dopaminergic neurotoxins. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
here, we demonstrate that transfection of vmat2 in the dopaminergic cell line, pc12, increases intracellular dopamine content, augments potassium-induced dopamine release and attenuates cell death induced by the cytosolic dopamine enhancer, methamphetamine, suggesting an enhancement in vesicular dopamine storage. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
in rat ventral mesencephalic cultures highly enriched for dopaminergic neurons, lentiviral delivery of recombinant vmat2 using a neuronal-specific promoter also resulted in elevated intracellular dopamine content and neurotransmitter release after depolarization. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
furthermore, using this vmat2 knockdown model, we are the first to report a direct link between enhanced cytoplasmic dopamine levels, measured following mild permeabilization of the plasma membrane using digitonin, and neurite degeneration in primary dopaminergic neurons. |
2008-03-28 |
2023-08-12 |
rat |
| Sandra Vergo, Jens Leander Johansen, Marcel Leist, Julie Lothariu. Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels. Brain research. vol 1185. 2008-03-28. PMID:18028884. |
in conclusion, our data support the hypothesis that an increase in vesicular sequestration of dopamine by modulation of vmat2 activity could restore neuronal function and enhance dopaminergic cell survival in conditions of dysregulated dopamine homeostasis such as parkinson's disease. |
2008-03-28 |
2023-08-12 |
rat |
| Teresa Cabaleiro, Ana Caride, Alejandro Romero, Anunciación Lafuent. Effects of in utero and lactational exposure to endosulfan in prefrontal cortex of male rats. Toxicology letters. vol 176. issue 1. 2008-03-27. PMID:18060705. |
endosulfan did not modify norepinephrine and dopamine content, but serotonin concentration was increased at pnd 30 and pnd 60 and serotoninergic and dopaminergic metabolism was also modified. |
2008-03-27 |
2023-08-12 |
rat |
| Oliver Pogarell, Walter Koch, Gabriele Pöpperl, Klaus Tatsch, Franziska Jakob, Christoph Mulert, Nicola Grossheinrich, Rainer Rupprecht, Hans-Jürgen Möller, Ulrich Hegerl, Frank Padber. Acute prefrontal rTMS increases striatal dopamine to a similar degree as D-amphetamine. Psychiatry research. vol 156. issue 3. 2008-03-25. PMID:17993266. |
here we investigated dopaminergic neurotransmission using single photon emission computed tomography (spect) and [(123)i]ibzm to indirectly assess the change in endogenous striatal dopamine concentration upon rtms as compared with d-amphetamine challenge. |
2008-03-25 |
2023-08-12 |
Not clear |
| Oliver Pogarell, Walter Koch, Gabriele Pöpperl, Klaus Tatsch, Franziska Jakob, Christoph Mulert, Nicola Grossheinrich, Rainer Rupprecht, Hans-Jürgen Möller, Ulrich Hegerl, Frank Padber. Acute prefrontal rTMS increases striatal dopamine to a similar degree as D-amphetamine. Psychiatry research. vol 156. issue 3. 2008-03-25. PMID:17993266. |
acute rtms challenge showed similar striatal dopaminergic effects to those associated with the administration of d-amphetamine, a substance known to increase synaptic dopamine. |
2008-03-25 |
2023-08-12 |
Not clear |