| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bart P de Kwaasteniet, Chedwa Pinto, Henricus G Ruhé, Eric H G Ruhé, Guido A van Wingen, Jan Booij, Damiaan Deny. Striatal dopamine D2/3 receptor availability in treatment resistant depression. PloS one. vol 9. issue 11. 2015-12-22. PMID:25411966. |
however, the role of dopaminergic signaling through measurement of striatal dopamine d(2/3) receptor (d2/3r) binding has not been investigated in trd subjects. |
2015-12-22 |
2023-08-13 |
human |
| S Scheggi, T Pelliccia, A Ferrari, M G De Montis, C Gambaran. Impramine, fluoxetine and clozapine differently affected reactivity to positive and negative stimuli in a model of motivational anhedonia in rats. Neuroscience. vol 291. 2015-12-21. PMID:25686523. |
the dopaminergic response to sucrose consumption was studied in non food-deprived rats in terms of dopamine d1 receptor signaling in the nucleus accumbens shell (nacs). |
2015-12-21 |
2023-08-13 |
rat |
| Guohua Yu, Huiyan Liu, Wei Zhou, Xuewei Zhu, Chao Yu, Na Wang, Yi Zhang, Ji Ma, Yulan Zhao, Yuanyuan Xu, Lujian Liao, Hongfang Ji, Chonggang Yuan, Jiyan M. In vivo protein targets for increased quinoprotein adduct formation in aged substantia nigra. Experimental neurology. vol 271. 2015-12-17. PMID:25956828. |
the selective vulnerability of dopaminergic neurons in the substantia nigra pars compacta in parkinson's disease, a late age onset neurodegenerative disorder, indicates the involvement of dopamine metabolism in the pathogenesis. |
2015-12-17 |
2023-08-13 |
rat |
| Yuichi Sakashita, Kenji Abe, Nobuyuki Katagiri, Toshie Kambe, Toshiaki Saitoh, Iku Utsunomiya, Yoshie Horiguchi, Kyoji Taguch. Effect of psilocin on extracellular dopamine and serotonin levels in the mesoaccumbens and mesocortical pathway in awake rats. Biological & pharmaceutical bulletin. vol 38. issue 1. 2015-12-15. PMID:25342005. |
in the present study, we examined the effects of systemically administered psilocin on extracellular dopamine and 5-ht concentrations in the ventral tegmental area (vta), nucleus accumbens, and medial prefrontal cortex of the dopaminergic pathway in awake rats using in vivo microdialysis. |
2015-12-15 |
2023-08-13 |
rat |
| Jia-Ling Wen, Li Xue, Run-Hua Wang, Zi-Xiang Chen, Yan-Wei Shi, Hu Zha. Involvement of the dopaminergic system in the consolidation of fear conditioning in hippocampal CA3 subregion. Behavioural brain research. vol 278. 2015-12-15. PMID:25446753. |
our data suggest that dopamine depletion in hippocampal subdivision ca3 may not be necessary for the acquisition of conditioned fear, but the expression of conditioned fear is likely dependent on the integrity of mesohippocampal dopaminergic connections. |
2015-12-15 |
2023-08-13 |
Not clear |
| Agnieszka Wąsik, Irena Romańska, Jerzy Michaluk, Lucyna Antkiewicz-Michalu. Chronic salsolinol administration prevents the behavioral and neurochemical effects of L-DOPA in rats. Neurotoxicity research. vol 27. issue 4. 2015-12-15. PMID:25711629. |
an ex vivo neurochemical experiment indicated that chronic but not acute salsolinol administration partially inhibited the l-dopa-induced increases in the concentration of dopamine and all of its metabolites in dopaminergic structures. |
2015-12-15 |
2023-08-13 |
rat |
| Xiang-Yun Li, Guang-Hai Mei, Qiang Dong, Yu Zhang, Zhuang-Li Guo, Jing-Jing Su, Yu-Ping Tang, Xue-Hong Jin, Hou-Guang Zhou, Yan-Yan Huan. Enhanced Neuroprotective Effects of Coadministration of Tetrandrine with Glutathione in Preclinical Model of Parkinson's Disease. Parkinson's disease. vol 2015. 2015-12-15. PMID:26664824. |
levels in the redox system, dopamine (da) metabolism, dopaminergic neuronal survival, and apoptosis of the substantia nigra (sn) and striatum, as well as the rotational behavior of animals were examined after a 50-day administration of gsh + tet (or gsh) and/or l-3,4-dihydroxyphenylalanine (l-dopa) to pd rats. |
2015-12-15 |
2023-08-13 |
rat |
| Juhee Lim, Hyo-In Kim, Yeojin Bang, Wongi Seol, Hueng-Sik Choi, Hyun Jin Cho. Hypoxia-inducible factor-1α upregulates tyrosine hydroxylase and dopamine transporter by nuclear receptor ERRγ in SH-SY5Y cells. Neuroreport. vol 26. issue 6. 2015-12-14. PMID:25807177. |
in the present study, we show for the first time that the orphan nuclear receptor estrogen-related receptor γ (errγ) is upregulated by hif-1α and plays essential roles in hif-1α-induced upregulation of dopaminergic marker molecules such as tyrosine hydroxylase and dopamine transporter. |
2015-12-14 |
2023-08-13 |
Not clear |
| I V Pavlova, M P Rysakova, M I Sergeev. [Influence of D1, D2 Receptor Blockade in Basolateral Amygdala on Behavior of Rats with High or Low Levels of Anxiety and Fear]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 65. issue 4. 2015-12-09. PMID:26601506. |
there was discovered different sensitivity of animals with different levels of anxiety and fear to the infusion of dopamine receptors antagonists in the amygdala that suggested the inequality of dopaminergic transmission in the amygdala of animals with individual differences. |
2015-12-09 |
2023-08-13 |
human |
| Jia Qi, Shiliang Zhang, Hui-Ling Wang, Huikun Wang, Jose de Jesus Aceves Buendia, Alexander F Hoffman, Carl R Lupica, Rebecca P Seal, Marisela Morale. A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons. Nature communications. vol 5. 2015-12-08. PMID:25388237. |
optogenetic vta activation of this projection elicits ampa-mediated synaptic excitatory currents in vta mesoaccumbens dopaminergic neurons and causes dopamine release in nucleus accumbens. |
2015-12-08 |
2023-08-13 |
Not clear |
| Tanveer Ahmad Mir, Mahmood H Akhtar, N G Gurudatt, Jeong-In Kim, Cheol Soo Choi, Yoon-Bo Shi. An amperometric nanobiosensor for the selective detection of K⁺-induced dopamine released from living cells. Biosensors & bioelectronics. vol 68. 2015-12-08. PMID:25617752. |
a highly sensitive amperometric sensor has been studied for selective monitoring of k(+)-induced dopamine released from dopaminergic cells (pc12) which is based on an edta immobilized-poly(1,5-diaminonaphthalne) (poly-dan) layer comprising graphene oxide (go) and gold nanoparticles (go/aunps). |
2015-12-08 |
2023-08-13 |
Not clear |
| Blanca Estela Jaramillo-Loranca, Linda Garcés-Ramírez, Alicia Angélica Munguía Rosales, Carolina Luna Ramírez, Genaro Vargas Hernández, Oscar Morales-Dionisio, Kateri González-Elizalde, Gonzalo Flores, Sergio Zamudio, Fidel De La Cruz-Lópe. The sigma agonist 1,3-di-o-tolyl-guanidine reduces the morphological and behavioral changes induced by neonatal ventral hippocampus lesion in rats. Synapse (New York, N.Y.). vol 69. issue 4. 2015-12-04. PMID:25682743. |
the sigma receptor agonist 1,3-di-o-tolyl-guanidine (dtg) was found to increase dopamine release in the striatum, nucleus accumbens, and prefrontal cortex, in a dose-dependent manner, after central as well as peripheral administration, suggesting a modulatory role of these receptors on the dopaminergic system. |
2015-12-04 |
2023-08-13 |
rat |
| Laetitia C Schwab, Shady N Garas, Shaady N Garas, Janelle Drouin-Ouellet, Sarah L Mason, Simon R Stott, Roger A Barke. Dopamine and Huntington's disease. Expert review of neurotherapeutics. vol 15. issue 4. 2015-12-04. PMID:25773746. |
pre-clinical and clinical studies have demonstrated an important role for the dopamine (da) system in hd with dopaminergic dysfunction at the level of both da release and da receptors. |
2015-12-04 |
2023-08-13 |
Not clear |
| Li Wang, Shujiang Shang, Xinjiang Kang, Sasa Teng, Feipeng Zhu, Bin Liu, Qihui Wu, Mingli Li, Wei Liu, Huadong Xu, Li Zhou, Ruiying Jiao, Haiqiang Dou, Panli Zuo, Xiaoyu Zhang, Lianghong Zheng, Shirong Wang, Changhe Wang, Zhuan Zho. Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine. Nature communications. vol 5. 2015-12-03. PMID:24968237. |
striatal dopamine (da) release can be independently triggered not only by action potentials (aps) in dopaminergic axons but also aps in cholinergic interneurons (chis). |
2015-12-03 |
2023-08-13 |
Not clear |
| Peter T Bell, Moran Gilat, Claire O'Callaghan, David A Copland, Michael J Frank, Simon J G Lewis, James M Shin. Dopaminergic basis for impairments in functional connectivity across subdivisions of the striatum in Parkinson's disease. Human brain mapping. vol 36. issue 4. 2015-12-03. PMID:25425542. |
the pathological hallmark of parkinson's disease is the degeneration of dopaminergic nigrostriatal neurons, leading to depletion of striatal dopamine. |
2015-12-03 |
2023-08-13 |
Not clear |
| Che-Sheng Chu, Nian-Sheng Tzeng, Hsin-An Chang, Chuan-Chia Chang, Tien-Yu Che. Killing two birds with one stone: the potential role of aripiprazole for patients with comorbid major depressive disorder and nicotine dependence via altering brain activity in the anterior cingulate cortex. Medical hypotheses. vol 83. issue 3. 2015-11-30. PMID:25109873. |
aripiprazole might act as a dopamine agonist similar to the way that bupropion does because of its partial dopamine d2 agonist and 30% intrinsic dopaminergic activity. |
2015-11-30 |
2023-08-13 |
Not clear |
| Hong Guo, Fang Shi, Meijiao Li, Qingqing Liu, Bin Yu, Limin H. Neuroprotective effects of Eucommia ulmoides Oliv. and its bioactive constituent work via ameliorating the ubiquitin-proteasome system. BMC complementary and alternative medicine. vol 15. 2015-11-30. PMID:25994206. |
parkinson's disease (pd) is a chronic neurodegenerative disorder characterized by a loss of dopaminergic neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor dysfunction. |
2015-11-30 |
2023-08-13 |
Not clear |
| I G Silki. [A Role of the Basal Ganglia in Processing of Complex Sounds and Auditory Attention]. Uspekhi fiziologicheskikh nauk. vol 46. issue 3. 2015-11-30. PMID:26506644. |
it follows from this mechanism that involuntary attention to sound tone can enhance an early component of the responses of neurons in the primary auditory cortical area (50 msec) in the absence of dopamine due to a disinhibition of thalamic neurons via the direct pathway through the basal ganglia, whereas voluntary attention to complex sounds can enhance only those components of responses of neurones in secondary auditory cortical areas which latencies exceeds latencies of dopaminergic cells (i.e. |
2015-11-30 |
2023-08-13 |
Not clear |
| Pei Jiang, Li-Hong Zhang, Hua-Lin Cai, Huan-De Li, Yi-Ping Liu, Mi-Mi Tang, Rui-Li Dang, Wen-Ye Zhu, Ying Xue, Xin H. Neurochemical effects of chronic administration of calcitriol in rats. Nutrients. vol 6. issue 12. 2015-11-25. PMID:25533012. |
however, the concentrations of the metabolites of dopamine and serotonin were increased and the drug use also resulted in a significant rise of monoamine oxidase a (maoa) expression, which might be responsible to maintain the homeostasis of dopaminergic and serotonergic neurotransmission. |
2015-11-25 |
2023-08-13 |
rat |
| M Ogata, K Noda, H Akita, H Ishibash. Characterization of nociceptive response to chemical, mechanical, and thermal stimuli in adolescent rats with neonatal dopamine depletion. Neuroscience. vol 289. 2015-11-25. PMID:25592423. |
these results suggest that the dopaminergic neural system plays a crucial role in the development of a neural network for tonic pain, including the spinal neural circuit for nociceptive transmission, and that the mechanism underlying hyperalgesia to tonic pain is not always consistent with that of spontaneous motor hyperactivity induced by neonatal dopamine depletion. |
2015-11-25 |
2023-08-13 |
rat |