| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Madhavi Tripathi, Geetanjali Arora, Chandan J Das, Tripti Grover, Ranjan Gupta, Chandrasekhar Ba. Incidental detection of intracranial tuberculomas on (99m)Tc-TRODAT-1 SPECT/CT. Clinical nuclear medicine. vol 40. issue 6. 2015-11-25. PMID:25608162. |
tc-trodat-1 has high affinity and specificity for dopamine transporters and is useful for the evaluation of presynaptic dopaminergic function, especially in parkinsonism. |
2015-11-25 |
2023-08-13 |
Not clear |
| Liang-Jen Wang, Sheng-Yu Lee, Shiou-Lan Chen, Yun-Hsuan Chang, Po See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Kao Chin Chen, I Hui Lee, Tzu-Yun Wang, Yen Kuang Yang, Ru-Band L. A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder. Scientific reports. vol 5. 2015-11-25. PMID:25744938. |
because dopaminergic disturbance is thought to be involved in the development of bipolar disorder (bpd), it seems essential to investigate dopamine-related genes like the catechol-o-methyltransferase (comt) gene, which are involved in dopamine metabolism, and the methylenetetrahydrofolate reductase (mthfr) gene, which may affect comt methylation and comt function. |
2015-11-25 |
2023-08-13 |
human |
| Vivek Verm. Classic Studies on the Interaction of Cocaine and the Dopamine Transporter. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 13. issue 3. 2015-11-24. PMID:26598579. |
thus, if more light is shed on the dopamine transporter-cocaine interaction, treatments for addiction and even other diseases of the dopaminergic system may not be too far ahead. |
2015-11-24 |
2023-08-13 |
Not clear |
| Guo Fen Ma, Noora Raivio, Josefa Sabrià, Jordi Orti. Agonist and antagonist effects of aripiprazole on D₂-like receptors controlling rat brain dopamine synthesis depend on the dopaminergic tone. The international journal of neuropsychopharmacology. vol 18. issue 4. 2015-11-20. PMID:25522390. |
agonist and antagonist effects of aripiprazole on d₂-like receptors controlling rat brain dopamine synthesis depend on the dopaminergic tone. |
2015-11-20 |
2023-08-13 |
rat |
| Thomas Mülle. Catechol-O-methyltransferase inhibitors in Parkinson's disease. Drugs. vol 75. issue 2. 2015-11-13. PMID:25559423. |
following transport across the blood-brain barrier and its metabolic conversion to dopamine, these peripheral 'ups and downs' of levodopa are reflected in fluctuating dopamine levels in the synaptic cleft between presynaptic and postsynaptic dopaminergic neurons of the nigrostriatal system. |
2015-11-13 |
2023-08-13 |
Not clear |
| T A Ignatowski, R Aalinkeel, J L Reynolds, B B Nair, D E Sykes, C P K Gleason, W C Law, M J Mammen, P N Prasad, S A Schwartz, Supriya D Mahaja. Nanotherapeutic approach for opiate addiction using DARPP-32 gene silencing in an animal model of opiate addiction. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 10. issue 1. 2015-11-12. PMID:25604667. |
opiates act on the dopaminergic system of the brain and perturb 32 kda dopamine and adenosine 3', 5'-monophosphate-regulated phosphoprotein (darpp-32) function. |
2015-11-12 |
2023-08-13 |
rat |
| L Zhao, L X He, S N Huang, L J Gong, L Li, Y Y Lv, Z M Qia. Protection of dopamine neurons by vibration training and up-regulation of brain-derived neurotrophic factor in a MPTP mouse model of Parkinson's disease. Physiological research. vol 63. issue 5. 2015-11-09. PMID:24908088. |
here, we investigated the effects of longer duration (4 weeks) of low amplitude vibration (lav) training on the numbers of dopaminergic neurons in the substantia nigra by immunostaining and the levels of dopamine (da) and brain-derived neurotrophic factor (bdnf) in the striatum by hplc and elisa in the chronic mptp lesion mouse. |
2015-11-09 |
2023-08-13 |
mouse |
| Paolo Solla, Antonino Cannas, Roberta Arca, Davide Fonti, Gianni Orofino, Francesco Marros. Focal (123)I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism. Case reports in neurological medicine. vol 2015. 2015-11-09. PMID:26550502. |
in cases of suspected vascular parkinsonism (vp), dopamine transporter spect has been highly recommended to exclude nigrostriatal dopaminergic degeneration. |
2015-11-09 |
2023-08-13 |
Not clear |
| Rafael Gonzalo-Gobernado, Lucia Calatrava-Ferreras, Juan Perucho, Diana Reimers, MarIa J Casarejos, Antonio S Herranz, Adriano Jimenez-Escrig, Juan J Diaz-Gil, Eulalia Baza. Liver growth factor as a tissue regenerating factor in neurodegenerative diseases. Recent patents on CNS drug discovery. vol 9. issue 3. 2015-11-06. PMID:25537484. |
furthermore, lgf treatment raises striatal dopamine levels and protects dopaminergic neurons in hemiparkinsonian animals. |
2015-11-06 |
2023-08-13 |
rat |
| Elisabeth Piccart, Nicholas A Courtney, Sarah Y Branch, Christopher P Ford, Michael J Beckstea. Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 31. 2015-11-05. PMID:26245975. |
neurotensin induces presynaptic depression of d2 dopamine autoreceptor-mediated neurotransmission in midbrain dopaminergic neurons. |
2015-11-05 |
2023-08-13 |
mouse |
| Elisabeth Piccart, Nicholas A Courtney, Sarah Y Branch, Christopher P Ford, Michael J Beckstea. Neurotensin Induces Presynaptic Depression of D2 Dopamine Autoreceptor-Mediated Neurotransmission in Midbrain Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 31. 2015-11-05. PMID:26245975. |
application of the modulatory peptide neurotensin (nt) to midbrain dopaminergic neurons transiently increases activity by decreasing d2 dopamine autoreceptor function, yet little is known about the mechanisms that underlie long-lasting effects. |
2015-11-05 |
2023-08-13 |
mouse |
| Xi-Jun He, Kazuyuki Uchida, Chiaki Megumi, Nobuaki Tsuge, Hiroyuki Nakayam. Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice. Journal of toxicologic pathology. vol 28. issue 4. 2015-11-05. PMID:26538809. |
treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) significantly induced the loss of dopaminergic cells in the substantia nigra and deletion of dopamine in the striatum, which was attenuated by long-term (7 weeks) dietary supplementation with curcumin at a concentration of 0.5% or 2.0% (w/w). |
2015-11-05 |
2023-08-13 |
mouse |
| Matej Markota, Jessica Sin, Harry Pantazopoulos, Rebecca Jonilionis, Sabina Berrett. Reduced dopamine transporter expression in the amygdala of subjects diagnosed with schizophrenia. Schizophrenia bulletin. vol 40. issue 5. 2015-11-03. PMID:24936023. |
this dat decrease may disrupt dopamine uptake, leading to increased dopaminergic synaptic transmission and spillage into the extracellular space with activation of extrasynaptic dopamine receptors. |
2015-11-03 |
2023-08-13 |
human |
| Wei Lu, Senthilkumar S Karuppagounder, Danielle A Springer, Michele D Allen, Lixin Zheng, Brittany Chao, Yan Zhang, Valina L Dawson, Ted M Dawson, Michael Lenard. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nature communications. vol 5. 2015-10-30. PMID:25222142. |
loss of pgam5 disables pink1-mediated mitophagy in vitro and leads to dopaminergic neurodegeneration and mild dopamine loss in vivo. |
2015-10-30 |
2023-08-13 |
mouse |
| Anthony Bosson, Sylvie Boisseau, Alain Buisson, Marc Savasta, Mireille Albrieu. Disruption of dopaminergic transmission remodels tripartite synapse morphology and astrocytic calcium activity within substantia nigra pars reticulata. Glia. vol 63. issue 4. 2015-10-29. PMID:25511180. |
the pharmacological blockade of dopaminergic transmission (with sulpiride and sch-23390) increased astrocyte calcium excitability, synchrony and gap junction coupling within the snr, suggesting a functional adaptation of astrocytes to dopamine transmission disruption in this output nucleus. |
2015-10-29 |
2023-08-13 |
rat |
| H-M Jin, S Shrestha Muna, T R Bagalkot, Y Cui, B K Yadav, Y-C Chun. The effects of social defeat on behavior and dopaminergic markers in mice. Neuroscience. vol 288. 2015-10-29. PMID:25575945. |
the present study investigated the effects of chronic social defeat stress on several behavioral parameters, and the expression of dopaminergic markers, i.e., dopamine d1 receptors (d1rs), dopamine d2 receptors (d2rs), and dopamine and cyclic adenosine 3',5'-monophosphate-regulated phosphoprotein-32 (darpp-32), in the prefrontal cortex (pfc), amygdala (amy), and hippocampus (hip) of mouse brains. |
2015-10-29 |
2023-08-13 |
mouse |
| Anna Brancato, Fulvio Plescia, Rosa Anna Maria Marino, Giuseppe Maniaci, Michele Navarra, Carla Cannizzar. Involvement of dopamine D2 receptors in addictive-like behaviour for acetaldehyde. PloS one. vol 9. issue 6. 2015-10-26. PMID:24926837. |
taken together, our data suggest that acetaldehyde exerts its own motivational properties, involving the dopaminergic transmission: indeed, activation of pre-synaptic d2-receptors by quinpirole, during extinction and relapse, negatively affects operant behaviour for acetaldehyde, likely decreasing acetaldehyde-induced dopamine release. |
2015-10-26 |
2023-08-13 |
Not clear |
| Shin-ichi Uchida, Kazuhiro Soshiroda, Eri Okita, Mika Kawai-Uchida, Akihisa Mori, Peter Jenner, Tomoyuki Kand. The adenosine A2A receptor antagonist, istradefylline enhances the anti-parkinsonian activity of low doses of dopamine agonists in MPTP-treated common marmosets. European journal of pharmacology. vol 747. 2015-10-26. PMID:25499739. |
in early pd, this may avoid dose escalation or allow a reduction in dopamine agonist dosage without a loss of efficacy and prevent dopaminergic side-effects from becoming treatment limiting. |
2015-10-26 |
2023-08-13 |
marmoset |
| Daniel Weintraub, Anthony S David, Andrew H Evans, Jon E Grant, Mark Stac. Clinical spectrum of impulse control disorders in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 2. 2015-10-22. PMID:25370355. |
icds have been most closely related to the use of dopamine agonists (das), perhaps more so at higher doses; in contrast, dds is primarily associated with shorter-acting, higher-potency dopaminergic medications, such as apomorphine and levodopa. |
2015-10-22 |
2023-08-13 |
Not clear |
| Z J Hall, S D Healy, S L Meddl. A role for nonapeptides and dopamine in nest-building behaviour. Journal of neuroendocrinology. vol 27. issue 2. 2015-10-21. PMID:25514990. |
because the nonapeptides, mesotocin and vasotocin and the neurotransmitter, dopamine, play important roles in avian social behaviour, we tested the hypothesis that mesotocinergic-vasotocinergic and dopaminergic neuronal populations in the social behaviour network and dopaminergic reward system, respectively, are active during nest building. |
2015-10-21 |
2023-08-13 |
Not clear |