| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sybren F de Kloet, Huibert D Mansvelder, Taco J De Vrie. Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors. Biochemical pharmacology. vol 97. issue 4. 2016-02-09. PMID:26208783. |
profound modulatory cholinergic input from the pedunculopontine and laterodorsal tegmentum to dopaminergic midbrain nuclei as well as local cholinergic interneuron projections to dopamine neuron axons in the striatum may play a major role in the effects of nicotine. |
2016-02-09 |
2023-08-13 |
Not clear |
| Shilpa Aggarwal, Seetal Dodd, Michael Ber. Restless leg syndrome associated with atypical antipsychotics: current status, pathophysiology, and clinical implications. Current drug safety. vol 10. issue 2. 2016-02-08. PMID:24861990. |
dopamine agonists and l-dopa reduce the symptoms of rls, and some agents that block the dopaminergic system aggravate rls. |
2016-02-08 |
2023-08-13 |
Not clear |
| Alexander A Nevue, Cameron J Elde, David J Perkel, Christine V Portfor. Dopaminergic Input to the Inferior Colliculus in Mice. Frontiers in neuroanatomy. vol 9. 2016-02-02. PMID:26834578. |
the principal auditory midbrain nucleus, the inferior colliculus (ic), is a likely location for dopaminergic modulation of auditory processing because it contains dopamine receptors and nerve terminals immunoreactive for tyrosine hydroxylase (th), the rate-limiting enzyme in dopamine synthesis. |
2016-02-02 |
2023-08-13 |
mouse |
| Alexander A Nevue, Cameron J Elde, David J Perkel, Christine V Portfor. Dopaminergic Input to the Inferior Colliculus in Mice. Frontiers in neuroanatomy. vol 9. 2016-02-02. PMID:26834578. |
we also immunostained for dopamine beta-hydroxylase (dbh), an enzyme critical for the conversion of dopamine to norepinephrine, to differentiate between dopaminergic and noradrenergic inputs. |
2016-02-02 |
2023-08-13 |
mouse |
| Neda Masoudi, Pablo Ibanez-Cruceyra, Sarah-Lena Offenburger, Alexander Holmes, Anton Gartne. Tetraspanin (TSP-17) protects dopaminergic neurons against 6-OHDA-induced neurodegeneration in C. elegans. PLoS genetics. vol 10. issue 12. 2016-01-29. PMID:25474638. |
in c. elegans, this drug is taken up by the presynaptic dopamine reuptake transporter (dat-1) and causes selective death of the eight dopaminergic neurons of the adult hermaphrodite. |
2016-01-29 |
2023-08-13 |
caenorhabditis_elegans |
| Omar Mamad, Claire Delaville, Wail Benjelloun, Abdelhamid Benazzou. Dopaminergic control of the globus pallidus through activation of D2 receptors and its impact on the electrical activity of subthalamic nucleus and substantia nigra reticulata neurons. PloS one. vol 10. issue 3. 2016-01-28. PMID:25742005. |
the globus pallidus (gp) receives dopaminergic afferents from the pars compacta of substantia nigra and several studies suggested that dopamine exerts its action in the gp through presynaptic d2 receptors (d2rs). |
2016-01-28 |
2023-08-13 |
rat |
| Agnes Norbury, Masud Husai. Sensation-seeking: Dopaminergic modulation and risk for psychopathology. Behavioural brain research. vol 288. 2016-01-27. PMID:25907745. |
both high tonic dopamine levels and hyper-reactive midbrain dopaminergic responses to signals of forthcoming reward are evident in higher sensations-seekers. |
2016-01-27 |
2023-08-13 |
human |
| Patrick Ejlerskov, Jeanette Göransdotter Hultberg, JunYang Wang, Robert Carlsson, Malene Ambjørn, Martin Kuss, Yawei Liu, Giovanna Porcu, Kateryna Kolkova, Carsten Friis Rundsten, Karsten Ruscher, Bente Pakkenberg, Tobias Goldmann, Desiree Loreth, Marco Prinz, David C Rubinsztein, Shohreh Issazadeh-Navika. Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia. Cell. vol 163. issue 2. 2016-01-26. PMID:26451483. |
mice lacking ifnb function exhibited motor and cognitive learning impairments with accompanying α-synuclein-containing lewy bodies in the brain, as well as a reduction in dopaminergic neurons and defective dopamine signaling in the nigrostriatal region. |
2016-01-26 |
2023-08-13 |
mouse |
| Xiao-Feng Yin, Hua-Min Xu, Yun-Xia Jiang, Yun-Lai Zhi, Yu-Xiu Liu, Heng-Wei Xiang, Kai Liu, Xiao-Dong Ding, Peng Su. Lentivirus-mediated Persephin over-expression in Parkinson's disease rats. Neural regeneration research. vol 10. issue 11. 2016-01-25. PMID:26807117. |
results found that the number of dopaminergic neurons in the substantia nigra increased, tyrosine hydroxylase expression was upregulated and concentrations of dopamine and its metabolites in corpus striatum were increased after pretreatment with persephin gene. |
2016-01-25 |
2023-08-13 |
rat |
| Reena Haobam, Debasmita Tripathy, Navneet A Kaidery, Kochupurackal P Mohanakuma. Embryonic stem cells derived neuron transplantation recovery in models of parkinsonism in relation to severity of the disorder in rats. Rejuvenation research. vol 18. issue 2. 2016-01-22. PMID:25546608. |
the severity of the disease was determined using the number of amphetamine- or apomorphine-induced rotations, striatal dopamine levels as estimated by high-performance liquid chromatography (hplc)-electrochemistry, and the number of surviving tyrosine hydroxylase immunoreactive dopaminergic neurons in the substantia nigra pars compacta. |
2016-01-22 |
2023-08-13 |
rat |
| Reena Haobam, Debasmita Tripathy, Navneet A Kaidery, Kochupurackal P Mohanakuma. Embryonic stem cells derived neuron transplantation recovery in models of parkinsonism in relation to severity of the disorder in rats. Rejuvenation research. vol 18. issue 2. 2016-01-22. PMID:25546608. |
rotational asymmetry in both models correlated significantly well with the loss in the number of nigral dopaminergic neurons and striatal dopamine depletion. |
2016-01-22 |
2023-08-13 |
rat |
| K H Stansfield, K N Ruby, B D Soares, J L McGlothan, X Liu, T R Guilart. Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. Translational psychiatry. vol 5. 2016-01-20. PMID:25756805. |
loss of pvgi inhibitory control to pyramidal cells alters the excitatory drive to midbrain dopamine neurons increasing subcortical dopaminergic activity. |
2016-01-20 |
2023-08-13 |
rat |
| K H Stansfield, K N Ruby, B D Soares, J L McGlothan, X Liu, T R Guilart. Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. Translational psychiatry. vol 5. 2016-01-20. PMID:25756805. |
we also show that pb(2+) animals exhibit a heightened locomotor response to cocaine and express significantly higher levels of dopamine metabolites and d2-dopamine receptors relative to controls indicative of subcortical dopaminergic hyperactivity. |
2016-01-20 |
2023-08-13 |
rat |
| Yijing Li, Yanfang Zuo, Peng Yu, Xingjie Ping, Cailian Cu. Role of basolateral amygdala dopamine D2 receptors in impulsive choice in acute cocaine-treated rats. Behavioural brain research. vol 287. 2016-01-19. PMID:25823760. |
although central dopamine transmission has been demonstrated to be involved in impulsivity and drug addiction, little is known regarding dopaminergic neurotransmission in addictive drug-induced alteration of impulse control. |
2016-01-19 |
2023-08-13 |
rat |
| Emily A Ferenczi, Kelly A Zalocusky, Conor Liston, Logan Grosenick, Melissa R Warden, Debha Amatya, Kiefer Katovich, Hershel Mehta, Brian Patenaude, Charu Ramakrishnan, Paul Kalanithi, Amit Etkin, Brian Knutson, Gary H Glover, Karl Deisserot. Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. Science (New York, N.Y.). vol 351. issue 6268. 2016-01-19. PMID:26722001. |
by using optogenetic functional magnetic resonance imaging to locally manipulate but globally visualize neural activity in rats, we found that dopamine neuron stimulation drives striatal activity, whereas locally increased mpfc excitability reduces this striatal response and inhibits the behavioral drive for dopaminergic stimulation. |
2016-01-19 |
2023-08-13 |
rat |
| Ichiro Kusumi, Shuken Boku, Yoshito Takahash. Psychopharmacology of atypical antipsychotic drugs: From the receptor binding profile to neuroprotection and neurogenesis. Psychiatry and clinical neurosciences. vol 69. issue 5. 2016-01-18. PMID:25296946. |
the dopaminergic modulations, including a low affinity for dopamine d2 receptors and a partial d2 receptor agonistic action, and glutamatergic regulations may also be involved in the pharmacological backgrounds of 'atypicality'. |
2016-01-18 |
2023-08-13 |
Not clear |
| Heleen A Slagter, Katerina Georgopoulou, Michael J Fran. Spontaneous eye blink rate predicts learning from negative, but not positive, outcomes. Neuropsychologia. vol 71. 2016-01-15. PMID:25823998. |
these observations support the notion that sebr reflects tonic dopamine levels, and suggest that sebr may specifically relate to dopamine d2 receptor function, given the importance of the dopaminergic d2 pathway in avoidance learning. |
2016-01-15 |
2023-08-13 |
Not clear |
| Trayambak Pathak, Tarjani Agrawal, Shlesha Richhariya, Sufia Sadaf, Gaiti Hasa. Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 40. 2016-01-13. PMID:26446229. |
the loss of orai-mediated soce alters transcriptional regulation of dopaminergic neurons, leading to downregulation of the enzyme tyrosine hydroxylase, which is essential for dopamine synthesis, and the dopamine transporter, which is required for dopamine uptake after synaptic release. |
2016-01-13 |
2023-08-13 |
drosophila_melanogaster |
| Trayambak Pathak, Tarjani Agrawal, Shlesha Richhariya, Sufia Sadaf, Gaiti Hasa. Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 40. 2016-01-13. PMID:26446229. |
these studies suggest that modulation of soce could serve as a novel mechanism for restoring dopamine levels in dopaminergic neurons. |
2016-01-13 |
2023-08-13 |
drosophila_melanogaster |
| Eleni Fanarioti, Maria Mavrikaki, George Panagis, Ada Mitsacos, George G Nomikos, Panagiotis Giompre. Behavioral and neurochemical changes in mesostriatal dopaminergic regions of the rat after chronic administration of the cannabinoid receptor agonist WIN55,212-2. The international journal of neuropsychopharmacology. vol 18. issue 6. 2016-01-12. PMID:25522428. |
the present study examined the effects of repeated administration of the nonselective cannabinoid receptor 1 agonist win55,212-2 on locomotor activity and on binding and mrna levels of dopamine receptors and transporters and gabaa receptors in mesostriatal dopaminergic regions of the rat. |
2016-01-12 |
2023-08-13 |
rat |