| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuko Takahashi-Niki, Ayako Inafune, Naruyuki Michitani, Yoshitaka Hatakeyama, Kotaro Suzuki, Mai Sasaki, Yoshihisa Kitamura, Takeshi Niki, Sanae M M Iguchi-Ariga, Hiroyoshi Arig. DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease. Journal of pharmacological sciences. vol 127. issue 3. 2016-04-05. PMID:25837927. |
five days after administration, the effects of compound-23 on mptp-induced locomotion deficits, on dopaminergic cell death and on brain dopamine levels were analyzed by rotor rod tests, by staining cells with an anti-th antibody and by an hplc, respectively. |
2016-04-05 |
2023-08-13 |
mouse |
| Fabienne S Sprenger, Klaus Seppi, Atbin Djamshidian, Eva Reiter, Michael Nocker, Katherina Mair, Georg Göbel, Werner Poew. Nonmotor symptoms in subjects without evidence of dopaminergic deficits. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 7. 2016-04-04. PMID:25772612. |
a subgroup of patients initially diagnosed with parkinson's disease (pd) turn out to have normal dopamine transporter single-photon emission computed tomography imaging and have been labeled as subjects without evidence of dopaminergic deficit (swedds). |
2016-04-04 |
2023-08-13 |
human |
| Gde Sasmita J Pande, Nguyen Thao Suong, Peter Bossier, Tom Defoird. The catecholamine stress hormones norepinephrine and dopamine increase the virulence of pathogenic Vibrio anguillarum and Vibrio campbellii. FEMS microbiology ecology. vol 90. issue 3. 2016-03-31. PMID:25264299. |
indeed, the dopaminergic receptor antagonist chlorpromazine neutralized the effect of dopamine, and the α-adrenergic receptor antagonists phentolamine and phenoxybenzamine neutralized the effect of norepinephrine, whereas the β-adrenergic receptor antagonist propranolol had limited to no effect. |
2016-03-31 |
2023-08-13 |
Not clear |
| J Schomaker, M Meete. Short- and long-lasting consequences of novelty, deviance and surprise on brain and cognition. Neuroscience and biobehavioral reviews. vol 55. 2016-03-31. PMID:25976634. |
third, spatial novelty may trigger the dopaminergic mesolimbic system, promoting dopamine release in the hippocampus, having longer-lasting effects, up to tens of minutes, on motivation, reward processing, and learning and memory. |
2016-03-31 |
2023-08-13 |
Not clear |
| O Lindval. Clinical translation of stem cell transplantation in Parkinson's disease. Journal of internal medicine. vol 279. issue 1. 2016-03-31. PMID:26332959. |
clinical trials of intrastriatal transplantation of human foetal mesencephalic tissue have shown that the grafted dopaminergic neurons re-innervate the striatum, restore striatal dopamine release and, in some cases, induce major, long-lasting improvement of motor function. |
2016-03-31 |
2023-08-13 |
human |
| Karlo J Lizarraga, Alessandra Gorgulho, Wei Chen, Antonio A De Salle. Molecular imaging of movement disorders. World journal of radiology. vol 8. issue 3. 2016-03-31. PMID:27029029. |
specific circuits such as the dopaminergic nigrostriatal projection can be studied with ligands that bind to the pre-synaptic dopamine transporter or post-synaptic dopamine receptors (d1 and d2). |
2016-03-31 |
2023-08-13 |
Not clear |
| T Krzymowski, S Stefanczyk-Krzymowsk. New facts and the concept of physiological regulation of the dopaminergic system function and its disorders. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 66. issue 3. 2016-03-30. PMID:26084215. |
we present the main results of the study and justification of our opinion on the role of dopamine (da) retrograde transfer in the cavernous sinus in the regulation of the dopaminergic (dargic) system activity. |
2016-03-30 |
2023-08-13 |
Not clear |
| Shahidee Zainal Abidin, Eng Liang Tan, Soon-Choy Chan, Ameerah Jaafar, Alex Xuen Lee, Mohd Hamdi Noor Abd Hamid, Nor Azian Abdul Murad, Nur Fadlina Pakarul Razy, Shahrul Azmin, Azlina Ahmad Annuar, Shen Yang Lim, Pike-See Cheah, King-Hwa Ling, Norlinah Mohamed Ibrahi. DRD and GRIN2B polymorphisms and their association with the development of impulse control behaviour among Malaysian Parkinson's disease patients. BMC neurology. vol 15. 2016-03-29. PMID:25896831. |
impulse control disorder (icd) and behaviours (icb) represent a group of behavioural disorders that have become increasingly recognised in parkinson's disease (pd) patients who previously used dopaminergic medications, particularly dopamine agonists and levodopa. |
2016-03-29 |
2023-08-13 |
Not clear |
| Maell Cullen, KongFatt Wong-Li. Integrated dopaminergic neuronal model with reduced intracellular processes and inhibitory autoreceptors. IET systems biology. vol 9. issue 6. 2016-03-25. PMID:26577159. |
dopamine (da) is an important neurotransmitter for multiple brain functions, and dysfunctions of the dopaminergic system are implicated in neurological and neuropsychiatric disorders. |
2016-03-25 |
2023-08-13 |
Not clear |
| Rachele Salvi, Tobias Steigleder, Johannes C M Schlachetzki, Elisabeth Waldmann, Stefan Schwab, Beate Winner, Jürgen Winkler, Zacharias Koh. Distinct Effects of Chronic Dopaminergic Stimulation on Hippocampal Neurogenesis and Striatal Doublecortin Expression in Adult Mice. Frontiers in neuroscience. vol 10. 2016-03-25. PMID:27013940. |
stimulating dopaminergic neurotransmission has the potential to enhance adult neurogenesis in the svz and the dg most likely via d2/d3 dopamine (da) receptors. |
2016-03-25 |
2023-08-13 |
mouse |
| Jolene Zheng, Mingming Wang, Wenqian Wei, Jeffrey N Keller, Binita Adhikari, Jason F King, Michael L King, Nan Peng, Roger A Lain. Dietary Plant Lectins Appear to Be Transported from the Gut to Gain Access to and Alter Dopaminergic Neurons of Caenorhabditis elegans, a Potential Etiology of Parkinson's Disease. Frontiers in nutrition. vol 3. 2016-03-25. PMID:27014695. |
post-feeding rhodamine- or tritc-tagged dietary lectins, the lectins were tracked from gut to dopaminergic neurons (daergic-n) in transgenic caenorhabditis elegans (c. elegans) [egis1(pdat-1:gfp)] where the mutant has the green fluorescent protein (gfp) gene fused to a dopamine transport protein gene labeling daergic-n. |
2016-03-25 |
2023-08-13 |
rat |
| Ismet Sarikay. PET imaging in neurology: Alzheimer's and Parkinson's diseases. Nuclear medicine communications. vol 36. issue 8. 2016-03-24. PMID:25920047. |
pet tracers targeting presynaptic dopaminergic function (f-dopa, radiolabeled pet tracers assessing the availability of dopamine transporters and vesicular monoamine transporters) and postsynaptic dopamine receptors are used to assess motor dysfunction in pd. |
2016-03-24 |
2023-08-13 |
Not clear |
| Jack Bergman, Curtis G Rheingol. Dopamine D₄ Receptor Antagonists for the Treatment of Cocaine Use Disorders. CNS & neurological disorders drug targets. vol 14. issue 6. 2016-03-23. PMID:26022267. |
in view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-selective dopamine d1-4 receptor antagonists. |
2016-03-23 |
2023-08-13 |
human |
| Roger A Barker, Janelle Drouin-Ouellet, Malin Parma. Cell-based therapies for Parkinson disease—past insights and future potential. Nature reviews. Neurology. vol 11. issue 9. 2016-03-21. PMID:26240036. |
given the success of pharmacological dopamine replacement, pursuit of cell-based dopamine replacement strategies seemed to be the next logical step, and studies were initiated over 30 years ago to explore the possibility of dopaminergic cell transplantation. |
2016-03-21 |
2023-08-13 |
Not clear |
| Sean L Hammond, Stephen Safe, Ronald B Tjalken. A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Neuroscience letters. vol 607. 2016-03-21. PMID:26383113. |
degeneration of dopaminergic neurons in parkinson's disease (pd) is associated with decreased expression of the orphan nuclear receptor nurr1 (nr4a2), which is critical for both homeostasis and development of dopamine (da) neurons. |
2016-03-21 |
2023-08-13 |
mouse |
| Hua-Guang Zheng, Rong Zhang, Xin Li, Fang-Fei Li, Ya-Chen Wang, Xue-Mei Wang, Ling-Long Lu, Tao Fen. Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography. Chinese medical journal. vol 128. issue 13. 2016-03-15. PMID:26112718. |
in this study, we aimed to assess the function of presynaptic dopaminergic neurons in patients with mrt by dopamine transporter positron emission tomography (dat-pet) and to evaluate the utility of clinical features or electrophysiological studies in differential diagnosis. |
2016-03-15 |
2023-08-13 |
Not clear |
| Sonal Agrawal, Ashish Singh, Pratibha Tripathi, Manisha Mishra, Pradhyumna Kumar Singh, Mahendra Pratap Sing. Cypermethrin-induced nigrostriatal dopaminergic neurodegeneration alters the mitochondrial function: a proteomics study. Molecular neurobiology. vol 51. issue 2. 2016-03-14. PMID:24760363. |
syndopa and minocycline rescued from cypermethrin induced augmentation in microglial activation and reductions in mitochondrial membrane potential and complex i activity, striatal dopamine content, and degeneration of nigral dopaminergic neurons. |
2016-03-14 |
2023-08-13 |
rat |
| Franco Borsini, Fabio Bordi, Andreina Poggi, Vincenzo Di Matte. Effects of ST1936, a selective serotonin-6 agonist, on electrical activity of putative mesencephalic dopaminergic neurons in the rat brain. Journal of psychopharmacology (Oxford, England). vol 29. issue 7. 2016-03-11. PMID:25735994. |
in the snc, acute systemic administration of st1936 had no effects on basal firing activity of these dopamine neurons; however, in the vta, st1936 induced either dose-related increases (45% of cells) or decreases in basal activity of these dopaminergic neurons. |
2016-03-11 |
2023-08-13 |
rat |
| Jongho Kim, Andrew G Horti, William B Mathews, Vladimir Pogorelov, Heather Valentine, James R Brasic, Daniel P Holt, Hayden T Ravert, Robert F Dannals, Luewi Zhou, Bruno Jedynak, Atsushi Kamiya, Mikhail V Pletnikov, Dean F Won. Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice. Molecular imaging and biology. vol 17. issue 3. 2016-03-08. PMID:25296765. |
we hypothesized that the mutant disc1 alters the homeostasis of multi-receptor interactions between dopaminergic [dopamine 2/3 (d(2/3)r)], glutamatergic [metabotropic glutamate 5 (mglur5)], cannabinoid 1 (cb(1)r), and nicotinic acetylcholine (α4β2-nachr) receptors in the brains of mice with inducible forebrain neuronal expression of dominant-negative mutant disc1. |
2016-03-08 |
2023-08-13 |
mouse |
| Rhona Clarke, Louise Adermar. Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol. Neural plasticity. vol 2015. 2016-03-08. PMID:26246915. |
dopamine is a key neurotransmitter in reward and reward-guided learning, and the physiological activity of gabaergic and cholinergic interneurons is regulated by dopaminergic transmission in a complex manner. |
2016-03-08 |
2023-08-13 |
Not clear |