| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Opeyemi J Olatunji, Yan Feng, Oyenike O Olatunji, Jian Tang, Zhen Ouyang, Zhaoliang S. Cordycepin protects PC12 cells against 6-hydroxydopamine induced neurotoxicity via its antioxidant properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 81. 2017-01-23. PMID:27261571. |
parkinson's disease (pd) is a progressive neurodegenerative disorder that is characterized by degeneration and loss of dopaminergic neurons of the substantia nigra. |
2017-01-23 |
2023-08-13 |
Not clear |
| Katarzyna Kuter, Manuela Kratochwil, Sven-Hendric Marx, Sonja Hartwig, Stephan Lehr, Michiru D Sugawa, Norbert A Denche. Native DIGE proteomic analysis of mitochondria from substantia nigra and striatum during neuronal degeneration and its compensation in an animal model of early Parkinson's disease. Archives of physiology and biochemistry. vol 122. issue 5. 2017-01-17. PMID:27467289. |
selective toxin 6-ohda was applied to kill dopaminergic neurons in substantia nigra and disturb neuronal transmission in striatum. |
2017-01-17 |
2023-08-13 |
Not clear |
| Zhan Liu, Hui-Qiao Chen, Yan Huang, Yi-Hua Qiu, Yu-Ping Pen. Transforming growth factor-β1 acts via TβR-I on microglia to protect against MPP(+)-induced dopaminergic neuronal loss. Brain, behavior, and immunity. vol 51. 2017-01-10. PMID:26254549. |
neuroinflammation is associated with pathogenesis of parkinson's disease (pd), a neurodegenerative disorder characterized by a progressive loss of dopaminergic (daergic) neurons within the substantia nigra. |
2017-01-10 |
2023-08-13 |
Not clear |
| Sheng-Huang Lin, Shih-Wei Chen, Yu-Chun Lo, Hsin-Yi Lai, Chich-Haung Yang, Shin-Yuan Chen, Yuan-Jen Chang, Chin-Hsing Chen, Wen-Tzeng Huang, Fu-Shan Jaw, You-Yin Chen, Siny Tsang, Lun-De Lia. Quantitative measurement of Parkinsonian gait from walking in monocular image sequences using a centroid tracking algorithm. Medical & biological engineering & computing. vol 54. issue 2-3. 2017-01-09. PMID:26109520. |
parkinson's disease (pd) is a neurodegenerative disease of the central nervous system that results from the degeneration of dopaminergic neurons in the substantia nigra. |
2017-01-09 |
2023-08-13 |
human |
| Armando De Virgilio, Antonio Greco, Giovanni Fabbrini, Maurizio Inghilleri, Maria Ida Rizzo, Andrea Gallo, Michela Conte, Chiara Rosato, Mario Ciniglio Appiani, Marco de Vincentii. Parkinson's disease: Autoimmunity and neuroinflammation. Autoimmunity reviews. vol 15. issue 10. 2017-01-03. PMID:27497913. |
parkinson's disease is a neurodegenerative disease that causes the death of dopaminergic neurons in the substantia nigra. |
2017-01-03 |
2023-08-13 |
Not clear |
| Armando De Virgilio, Antonio Greco, Giovanni Fabbrini, Maurizio Inghilleri, Maria Ida Rizzo, Andrea Gallo, Michela Conte, Chiara Rosato, Mario Ciniglio Appiani, Marco de Vincentii. Parkinson's disease: Autoimmunity and neuroinflammation. Autoimmunity reviews. vol 15. issue 10. 2017-01-03. PMID:27497913. |
microscopically, the specific degeneration of dopaminergic neurons in the substantia nigra and the presence of lewy bodies, which are brain deposits containing a substantial amount of α-synuclein, have been recognized. |
2017-01-03 |
2023-08-13 |
Not clear |
| Candace H Carriere, Na Hyea Kang, Lennard P Nile. Chronic low-dose melatonin treatment maintains nigrostriatal integrity in an intrastriatal rotenone model of Parkinson's disease. Brain research. vol 1633. 2016-12-26. PMID:26740407. |
parkinson's disease is a major neurodegenerative disorder which primarily involves the loss of dopaminergic neurons in the substantia nigra and related projections in the striatum. |
2016-12-26 |
2023-08-13 |
rat |
| Xiao-Ling Qin, Qing-Shan Zhang, Li Sun, Meng-Wei Hao, Zhao-Ting H. Lower Serum Bilirubin and Uric Acid Concentrations in Patients with Parkinson's Disease in China. Cell biochemistry and biophysics. vol 72. issue 1. 2016-12-19. PMID:25449297. |
it is possible that individuals with decreased serum bilirubin and ua concentrations lack the endogenous defense system to prevent peroxynitrite and other free radicals from damaging and destroying dopaminergic cells in the substantia nigra. |
2016-12-19 |
2023-08-13 |
Not clear |
| Juan C Jurado-Coronel, Marco Ávila-Rodriguez, Valentina Echeverria, Oscar Alejandro Hidalgo, Janneth Gonzalez, Gjumrakch Aliev, George E Barret. Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. CNS & neurological disorders drug targets. vol 15. issue 3. 2016-12-19. PMID:26831259. |
parkinson's disease (pd) is the second more common neurodegenerative disorders, after alzheimer's disease and is characterized by degeneration of dopaminergic neurons in the pars compact of the substantia nigra of the basal ganglia. |
2016-12-19 |
2023-08-13 |
Not clear |
| Gessynger Morais-Silva, Mariane Ferreira-Santos, Marcelo T Mari. Conessine, an H3 receptor antagonist, alters behavioral and neurochemical effects of ethanol in mice. Behavioural brain research. vol 305. 2016-12-16. PMID:26924015. |
the blockade of h3 receptors and ethanol seem to interact in the modulation of dopaminergic neurotransmission of nigrostriatal pathway, decreasing dopamine metabolites in substantia nigra. |
2016-12-16 |
2023-08-13 |
mouse |
| Heung Deok Kim, Kyoung Hoon Jeong, Un Ju Jung, Sang Ryong Ki. Myricitrin Ameliorates 6-Hydroxydopamine-Induced Dopaminergic Neuronal Loss in the Substantia Nigra of Mouse Brain. Journal of medicinal food. vol 19. issue 4. 2016-12-16. PMID:26991235. |
myricitrin ameliorates 6-hydroxydopamine-induced dopaminergic neuronal loss in the substantia nigra of mouse brain. |
2016-12-16 |
2023-08-13 |
mouse |
| Yun-Il Lee, Hojin Kang, Young Wan Ha, Ki-Young Chang, Sung-Chun Cho, Sang Ok Song, Hyein Kim, Areum Jo, Rin Khang, Jeong-Yun Choi, Yunjong Lee, Sang Chul Park, Joo-Ho Shi. Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss. Neurobiology of aging. vol 41. 2016-12-15. PMID:27103513. |
during normal aging, the number of dopaminergic (da) neurons in the substantia nigra progressively diminishes, although massive da neuronal loss is a hallmark sign of parkinson's disease. |
2016-12-15 |
2023-08-13 |
mouse |
| Fabrine Sales Massafera Tristão, Márcio Lazzarini, Sabine Martin, Majid Amar, Walter Stühmer, Frank Kirchhoff, Lucas Araújo Caldi Gomes, Laurance Lanfumey, Rui D Prediger, Julia E Sepulveda, Elaine A Del-Bel, Rita Raisman-Vozar. CX3CR1 Disruption Differentially Influences Dopaminergic Neuron Degeneration in Parkinsonian Mice Depending on the Neurotoxin and Route of Administration. Neurotoxicity research. vol 29. issue 3. 2016-12-13. PMID:26403659. |
in contrast to that, we could not see differences in the number of dopaminergic neurons in the substantia nigra of cx3cr1-deficient animals. |
2016-12-13 |
2023-08-13 |
mouse |
| Fabrine Sales Massafera Tristão, Márcio Lazzarini, Sabine Martin, Majid Amar, Walter Stühmer, Frank Kirchhoff, Lucas Araújo Caldi Gomes, Laurance Lanfumey, Rui D Prediger, Julia E Sepulveda, Elaine A Del-Bel, Rita Raisman-Vozar. CX3CR1 Disruption Differentially Influences Dopaminergic Neuron Degeneration in Parkinsonian Mice Depending on the Neurotoxin and Route of Administration. Neurotoxicity research. vol 29. issue 3. 2016-12-13. PMID:26403659. |
after the 6-ohda inoculation, a minor dopaminergic neuronal loss was observed in the substantia nigra from cx3cr1-deficient mice. |
2016-12-13 |
2023-08-13 |
mouse |
| Shuai Zhang, Si-Yuan Shao, Xiu-Yun Song, Cong-Yuan Xia, Ya-Nan Yang, Pei-Cheng Zhang, Nai-Hong Che. Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity. Neurotoxicology. vol 52. 2016-12-13. PMID:26408940. |
gavage administration of fs8 (50 and 200mg/kg, but not 10mg/kg) for 25 days significantly improved the behavior function, decreased the loss of dopaminergic neurons in substantia nigra (sn), and maintained the level of dopamine in striatum after unilateral infusion of rotenone in sn. |
2016-12-13 |
2023-08-13 |
Not clear |
| Su-Ping Peng, Sjef Copra. Comparison of Human Primary with Human iPS Cell-Derived Dopaminergic Neuron Grafts in the Rat Model for Parkinson's Disease. Stem cell reviews and reports. vol 12. issue 1. 2016-12-13. PMID:26438376. |
neuronal degeneration within the substantia nigra and the loss of the dopaminergic nigro-striatal pathway are the major hallmarks of parkinson's disease (pd). |
2016-12-13 |
2023-08-13 |
human |
| Roberta Filograna, Mariano Beltramini, Luigi Bubacco, Marco Bisagli. Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View. Current neuropharmacology. vol 14. issue 3. 2016-12-13. PMID:26517052. |
parkinson's disease (pd) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (daergic) neurons in the substantia nigra. |
2016-12-13 |
2023-08-13 |
Not clear |
| Fereshteh Mehraein, Maryam Sarbishegi, Zoleikha Golipoo. Different effects of olive leaf extract on antioxidant enzyme activities in midbrain and dopaminergic neurons of Substantia Nigra in young and old rats. Histology and histopathology. vol 31. issue 4. 2016-12-13. PMID:26559661. |
different effects of olive leaf extract on antioxidant enzyme activities in midbrain and dopaminergic neurons of substantia nigra in young and old rats. |
2016-12-13 |
2023-08-13 |
rat |
| Fereshteh Mehraein, Maryam Sarbishegi, Zoleikha Golipoo. Different effects of olive leaf extract on antioxidant enzyme activities in midbrain and dopaminergic neurons of Substantia Nigra in young and old rats. Histology and histopathology. vol 31. issue 4. 2016-12-13. PMID:26559661. |
study of the effects of olive leaf extract on antioxidant enzyme activities in midbrain and dopaminergic neurons of substantia nigra in young and old rats. |
2016-12-13 |
2023-08-13 |
rat |
| Y Pang, S Lin, C Wright, J Shen, K Carter, A Bhatt, L-W Fa. Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats. Neuroscience. vol 318. 2016-12-13. PMID:26777890. |
protection of substantia nigra (sn) dopaminergic (da) neurons by neurotrophic factors (ntfs) is one of the promising strategies in parkinson's disease (pd) therapy. |
2016-12-13 |
2023-08-13 |
human |