| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Apicella, E Legallet, A Nieoullon, E Trouch. Neglect of contralateral visual stimuli in monkeys with unilateral striatal dopamine depletion. Behavioural brain research. vol 46. issue 2. 1992-03-23. PMID:1786125. |
unilateral lesions of the nigrostriatal dopaminergic system were induced by injecting 6-hydroxydopamine into the substantia nigra of three monkeys trained to initiate arm movements in response to stimuli randomly presented at various locations in their immediate visual space. |
1992-03-23 |
2023-08-11 |
monkey |
| F Thibaut, E C Hirsch, R Raisman, F Javoy-Agid, Y Agi. Microtopography of D1 dopaminergic binding sites in the human substantia nigra: an autoradiographic study. Neuroscience. vol 37. issue 2. 1992-03-10. PMID:1983469. |
microtopography of d1 dopaminergic binding sites in the human substantia nigra: an autoradiographic study. |
1992-03-10 |
2023-08-11 |
human |
| F Thibaut, E C Hirsch, R Raisman, F Javoy-Agid, Y Agi. Microtopography of D1 dopaminergic binding sites in the human substantia nigra: an autoradiographic study. Neuroscience. vol 37. issue 2. 1992-03-10. PMID:1983469. |
binding densities were similar in pars compacta and pars reticulata of the substantia nigra, except for a peak value of high [3h]sch 23390 in the pars reticulata, at a level just ventral to a zone of hyperdensity of melanized dopaminergic neurons in the pars compacta. |
1992-03-10 |
2023-08-11 |
human |
| M Mavridis, F C Colpaert, M J Milla. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra-lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists. Brain research. vol 562. issue 2. 1992-03-03. PMID:1685341. |
in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra (sn), the indirect dopaminergic agonist, (+)-amphetamine (amph), dose-dependently induced robust, ipsilateral rotation: this could be dose-dependently abolished by the dopamine (d2/d1) antagonist, haloperidol. |
1992-03-03 |
2023-08-11 |
rat |
| B Giros, S el Mestikawy, L Bertrand, M G Caro. Cloning and functional characterization of a cocaine-sensitive dopamine transporter. FEBS letters. vol 295. issue 1-3. 1992-02-20. PMID:1765147. |
in situ hybridization reveals that the mrna for this transporter is expressed in the substantia nigra and ventral tegmental area, regions that contain dopaminergic cell bodies. |
1992-02-20 |
2023-08-11 |
rat |
| K R Melia, K Rasmussen, R Z Terwilliger, J W Haycock, E J Nestler, R S Duma. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: effects of chronic stress and drug treatments. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1345939. |
chronic (5 days) cold exposure significantly increased levels of th immunoreactivity in the lc, as previously reported, but not in substantia nigra (sn) or ventral tegmentum (vt), two dopaminergic nuclei studied for comparison. |
1992-02-13 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, B Sjöholm, E Syvälaht. Effects of acute administration of SCH 23390 on dopamine and serotonin turnover in major dopaminergic areas and mesencephalic raphe nuclei--comparison with ritanserin. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1722342. |
the effects of acute administration of sch 23390 (0.05 and 0.25 mg/kg s.c.), a dopamine d-1 receptor antagonist having also a moderate serotonin-s2 (5-ht-2) receptor blocking activity, and ritanserin (0.5 mg/kg), a specific 5-ht-2 antagonist, on dopamine (da) and serotonin (5-ht) turnover were investigated in dopaminergic (nucleus caudatus, nucleus accumbens, substantia nigra, a10 area) and serotonergic (nucleus raphe dorsalis and nucleus raphe medialis) rat brain nuclei. |
1992-02-13 |
2023-08-11 |
rat |
| M W Cleeter, J M Cooper, A H Schapir. Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1729421. |
the generation of free radicals by neurotoxin-induced inhibition of complex i has important implications for our interpretation of the increased oxidative stress observed in parkinson's disease substantia nigra and for our understanding of the cause(s) of dopaminergic cell death in this disorder. |
1992-02-13 |
2023-08-11 |
Not clear |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Nomifensine but not amantadine increases dopamine-induced responses on rat substantia nigra zona compacta neurons. Neuroscience letters. vol 131. issue 2. 1992-02-12. PMID:1662338. |
while our results provide electrophysiological evidence for an inhibition of the dopamine uptake system by nomifensine, they do not support a dopaminergic mechanism for the actions of amantadine in the substantia nigra zona compacta. |
1992-02-12 |
2023-08-11 |
rat |
| S A Jones, J R Ellis, A Klegeris, S A Greenfiel. The relationship between visual stimulation, behaviour and continuous release of protein in the substantia nigra. Brain research. vol 560. issue 1-2. 1992-02-11. PMID:1760724. |
in the substantia nigra, a protein (acetylcholinesterase) is secreted from the dendrites of dopaminergic pars compacta neurons, in a noncholinergic capacity. |
1992-02-11 |
2023-08-11 |
Not clear |
| G Pezzoli, A Zecchinelli, S Ricciardi, R E Burke, S Fahn, G Scarlato, A Carenz. Intraventricular infusion of epidermal growth factor restores dopaminergic pathway in hemiparkinsonian rats. Movement disorders : official journal of the Movement Disorder Society. vol 6. issue 4. 1992-02-05. PMID:1684638. |
we assessed the effect of a 35-day delayed intracerebroventricular (icv) infusion of epidermal growth factor (egf) on the survival and function of the substantia nigra (sn) dopaminergic neurons after a unilateral mechanical transection of rat nigrostriatal pathway. |
1992-02-05 |
2023-08-11 |
rat |
| M Diana, L Pani, Z Rossetti, N Passino, G L Gess. Flunarizine attenuates cocaine-induced inhibition of A9 dopaminergic neurons. Pharmacological research. vol 24. issue 2. 1992-01-22. PMID:1661005. |
the intravenous administration of cocaine (0.5-8 mg/kg) produced a dose-related inhibition of the firing rate of substantia nigra (a9) dopaminergic (da) neurons. |
1992-01-22 |
2023-08-11 |
Not clear |
| A Elverfors, H Nissbrand. Reserpine-insensitive dopamine release in the substantia nigra? Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1720998. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic pathway, but also from the dendrites in the substantia nigra (sn). |
1992-01-22 |
2023-08-11 |
Not clear |
| A M Allen, G Paxinos, M J McKinley, S Y Chai, F A Mendelsoh. Localization and characterization of angiotensin II receptor binding sites in the human basal ganglia, thalamus, midbrain pons, and cerebellum. The Journal of comparative neurology. vol 312. issue 2. 1992-01-21. PMID:1748734. |
the high density of ang ii receptor binding in the substantia nigra occurs over pigmented, presumably dopaminergic, neurons. |
1992-01-21 |
2023-08-11 |
human |
| M A Castellano, M Rodriguez Dia. Nigrostriatal dopaminergic cell activity is under control by substantia nigra of the contralateral brain side: electrophysiological evidence. Brain research bulletin. vol 27. issue 2. 1992-01-13. PMID:1742610. |
nigrostriatal dopaminergic cell activity is under control by substantia nigra of the contralateral brain side: electrophysiological evidence. |
1992-01-13 |
2023-08-11 |
Not clear |
| V A Peduto, A Concas, G Santoro, G Biggio, G L Gess. Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology. vol 75. issue 6. 1992-01-06. PMID:1660227. |
in vivo, the effect of propofol was studied using single-unit recording of the electrical activity of both nondopaminergic neurons in the pars reticulata of the substantia nigra (pr neurons) and of dopaminergic neurons in the pars compacta of the substantia nigra (da neurons). |
1992-01-06 |
2023-08-11 |
rat |
| C Cerruti, M J Drian, J M Kamenka, A Priva. Localization of dopamine carriers by BTCP, a dopamine uptake inhibitor, on nigral cells cultured in vitro. Brain research. vol 555. issue 1. 1991-12-20. PMID:1681995. |
btcp, n-[1-(2-benzo(b)thiopenyl)cyclohexyl]piperidine, a derivative of phencyclidine, acted as a potent dopamine (da) uptake blocking agent on primary cultures of dopaminergic neurons obtained from substantia nigra (ic50 = 70 nm). |
1991-12-20 |
2023-08-11 |
Not clear |
| F C Zhou, S Bledsoe, J Murph. Serotonergic sprouting is induced by dopamine-lesion in substantia nigra of adult rat brain. Brain research. vol 556. issue 1. 1991-12-03. PMID:1718555. |
dopaminergic neurotoxin, 6-hydroxydopamine (6-ohda), was injected directly into the substantia nigra of adult rats. |
1991-12-03 |
2023-08-11 |
rat |
| J T Greenamyre, C F O'Brie. N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. Archives of neurology. vol 48. issue 9. 1991-11-22. PMID:1835370. |
moreover, nmda antagonists provide profound protection of dopaminergic neurons of the substantia nigra in the mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and methamphetamine models of parkinson's disease. |
1991-11-22 |
2023-08-11 |
Not clear |
| T B Freeman, M S Spence, B D Boss, D H Spector, R E Strecker, C W Olanow, J H Kordowe. Development of dopaminergic neurons in the human substantia nigra. Experimental neurology. vol 113. issue 3. 1991-11-19. PMID:1680741. |
development of dopaminergic neurons in the human substantia nigra. |
1991-11-19 |
2023-08-11 |
human |