| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D M Gao, L Jeaugey, P Pollak, A L Benabi. Intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:2282499. |
intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. |
1991-03-19 |
2023-08-11 |
rat |
| K P Gudehithlu, A M Duchemin, G A Tejwani, N H Neff, M Hadjiconstantino. Preproenkephalin mRNA and methionine-enkephalin increase in mouse striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1899692. |
dopaminergic neurons that project to the striatum from the substantia nigra are thought to modulate methionine-enkephalin (met-enk) metabolism in the striatum. |
1991-03-15 |
2023-08-11 |
mouse |
| M E Ehrlich, T Kurihara, P Greengar. Rat DARPP-32: cloning, sequencing, and characterization of the cDNA. Journal of molecular neuroscience : MN. vol 2. issue 1. 1991-01-31. PMID:1979497. |
unilateral destruction of the nigrostriatal dopaminergic pathway by injection of 6-hydroxydopamine (6-ohda) into the substantia nigra did not alter the striatal steady state levels of darpp-32 mrna. |
1991-01-31 |
2023-08-11 |
rat |
| F Javoy-Agid, E C Hirsch, S Dumas, C Duyckaerts, J Mallet, Y Agi. Decreased tyrosine hydroxylase messenger RNA in the surviving dopamine neurons of the substantia nigra in Parkinson's disease: an in situ hybridization study. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:1979431. |
parkinson's disease is associated with a massive loss in melanized dopaminergic neurons in the substantia nigra resulting in a severe striatal dopaminergic denervation. |
1991-01-24 |
2023-08-11 |
Not clear |
| C R Gerfen, T M Engber, L C Mahan, Z Susel, T N Chase, F J Monsma, D R Sible. D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science (New York, N.Y.). vol 250. issue 4986. 1991-01-22. PMID:2147780. |
the striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. |
1991-01-22 |
2023-08-11 |
rat |
| S J Taylor, S A Jones, J Haggblad, S A Greenfiel. "On-line" measurement of acetylcholinesterase release from the substantia nigra of the freely-moving guinea-pig. Neuroscience. vol 37. issue 1. 1991-01-02. PMID:2243598. |
acetylcholinesterase is released from dopaminergic cells within the substantia nigra. |
1991-01-02 |
2023-08-11 |
Not clear |
| G M Pasinetti, D G Morgan, S A Johnson, S L Millar, C E Finc. Tyrosine hydroxylase mRNA concentration in midbrain dopaminergic neurons is differentially regulated by reserpine. Journal of neurochemistry. vol 55. issue 5. 1990-11-20. PMID:1976760. |
tyrosine hydroxylase (th)-mrna, assayed by in situ hybridization combined with th immunocytochemistry, showed a selective increase in the ventral tegmental area (a-10) but not in the substantia nigra (a-9) midbrain dopaminergic (daergic) neurons 3 days after reserpine treatment. |
1990-11-20 |
2023-08-11 |
Not clear |
| T H McNeill, L L Koe. Differential effects of advancing age on neurotransmitter cell loss in the substantia nigra and striatum of C57BL/6N mice. Brain research. vol 521. issue 1-2. 1990-11-09. PMID:1976411. |
the present study was carried out to examine the extrapyramidal motor system of c57bl/6n mice for age-related cell loss in cholinergic neurons of the striatum (st) and dopaminergic (da) neurons of the substantia nigra (sn). |
1990-11-09 |
2023-08-11 |
mouse |
| H Bergman, T Wichmann, M R DeLon. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science (New York, N.Y.). vol 249. issue 4975. 1990-10-26. PMID:2402638. |
although it is known that parkinson's disease results from a loss of dopaminergic neurons in the substantia nigra, the resulting alterations in activity in the basal ganglia responsible for parkinsonian motor deficits are still poorly characterized. |
1990-10-26 |
2023-08-11 |
monkey |
| B J Morris, A Herz, V Höll. Localization of striatal opioid gene expression, and its modulation by the mesostriatal dopamine pathway: an in situ hybridization study. Journal of molecular neuroscience : MN. vol 1. issue 1. 1990-10-26. PMID:2561993. |
the mesostriatal dopaminergic pathway was destroyed by discrete, unilateral injection of 6-hydroxy-dopamine (6-ohda) into either the substantia nigra or the neighboring ventral tegmental area (vta). |
1990-10-26 |
2023-08-11 |
rat |
| M F Pozza, H R Olpe, F Brugger, G E Fag. Electrophysiological characterization of a novel potent and orally active NMDA receptor antagonist: CGP 37849 and its ethylester CGP 39551. European journal of pharmacology. vol 182. issue 1. 1990-10-19. PMID:1976098. |
nmda excited dopaminergic cells in the pars compacta region of the substantia nigra in a concentration-dependent manner. |
1990-10-19 |
2023-08-11 |
rat |
| S R Vincent, B T Hope, S L Drinnan, P B Reine. G protein mRNA expression in immunohistochemically identified dopaminergic and noradrenergic neurons in the rat brain. Synapse (New York, N.Y.). vol 6. issue 1. 1990-10-18. PMID:2119071. |
the results indicate that the dopaminergic neurons of the substantia nigra and the noradrenergic neurons of the locus ceruleus express the mrna for the alpha subunits of all three of these g proteins. |
1990-10-18 |
2023-08-11 |
rat |
| M Tanaka, A Sotomatsu, H Kanai, S Hira. [Iron-dependent cytotoxic effects of dopa on cultured neurons of the dorsal root ganglia]. Rinsho shinkeigaku = Clinical neurology. vol 30. issue 4. 1990-09-21. PMID:2117513. |
in parkinson's disease, the cytotoxic mechanism of dopa and iron may involve the neuronal degeneration in the substantia nigra abundant in iron and dopaminergic neurons. |
1990-09-21 |
2023-08-11 |
mouse |
| A Hes. The effects of monoamine oxidase inhibition and dopamine uptake blockade on MPTP-induced increase of 2-[3H]deoxyglucose uptake in specific mesencephalic catecholaminergic nuclei. Neuroscience letters. vol 112. issue 1. 1990-09-20. PMID:2143566. |
intraperitoneal injection in c57 black mice of 30 or 7.5 mg/kg mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) followed 1-2 h later by 0.5 mci/100 g 2-[3h]deoxyglucose (2-dg) produces an intense increase of 2-dg uptake in the dopaminergic zona compacta (zc) of the substantia nigra and the adjacent ventral tegmental area (vta) as seen in autoradiographs. |
1990-09-20 |
2023-08-11 |
mouse |
| M H Heijna, M Padt, F Hogenboom, P S Portoghese, A H Mulder, A N Schoffelmee. Opioid receptor-mediated inhibition of dopamine and acetylcholine release from slices of rat nucleus accumbens, olfactory tubercle and frontal cortex. European journal of pharmacology. vol 181. issue 3. 1990-09-18. PMID:2166675. |
the results indicate that the inhibitory effects of opioids on the in vitro release of da from dopaminergic nerve fibres arising from the substantia nigra and the ventral tegmental area are mediated by presynaptic kappa receptors only. |
1990-09-18 |
2023-08-11 |
rat |
| H A Se. Differentiation gradient of dopaminergic neurons in substantia nigra of rat. Shi yan sheng wu xue bao. vol 23. issue 1. 1990-09-11. PMID:1974379. |
differentiation gradient of dopaminergic neurons in substantia nigra of rat. |
1990-09-11 |
2023-08-11 |
rat |
| H A Se. Differentiation gradient of dopaminergic neurons in substantia nigra of rat. Shi yan sheng wu xue bao. vol 23. issue 1. 1990-09-11. PMID:1974379. |
the chemical differentiation featured by the appearance of tyrosine hydroxylase (th) and the distribution pattern of the dopaminergic cells of rat substantia nigra (sn) were studied with combined immunocytochemical and electronmicroscopic techniques. |
1990-09-11 |
2023-08-11 |
rat |
| H Dabadie, M Geffard, J Paccali. [Simultaneous detection of tryptamine and dopamine in the substantia nigra and raphe nuclei in rats using specific antibodies]. Therapie. vol 45. issue 3. 1990-08-08. PMID:2363116. |
secondly, using a monoclonal anti-dopamine (da) antibody and our anti-t antibodies, the simultaneous and specific detection of these compounds enabled us to define the chemically relationships existing between the dopaminergic and tryptaminergic neuronal systems from substantia nigra to raphe nuclei. |
1990-08-08 |
2023-08-11 |
rat |
| D J Doudet, C Gross, M Arluison, B Bioula. Modifications of precentral cortex discharge and EMG activity in monkeys with MPTP-induced lesions of DA nigral neurons. Experimental brain research. vol 80. issue 1. 1990-08-01. PMID:1972680. |
the dopaminergic (da) neurons of the substantia nigra (sn) were destroyed selectively by repeated series of intravenous injections of mptp. |
1990-08-01 |
2023-08-11 |
monkey |
| J C Copray, R S Liem, G J Ter Horst, J D van Willige. Dopaminergic afferents to the mesencephalic trigeminal nucleus of the rat: a light and electron microscope immunocytochemistry study. Brain research. vol 514. issue 2. 1990-08-01. PMID:2357546. |
these dopaminergic afferents originate from the substantia nigra, the ventral tegmental area and the medial hypothalamus. |
1990-08-01 |
2023-08-11 |
rat |