| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Carrera, R Mattioli, C Toma. Preoperative operant circling training facilitates recovery following unilateral substantia nigra lesion in rats. Behavioral and neural biology. vol 58. issue 1. 1992-11-04. PMID:1417669. |
this study was undertaken to examine (1) whether pre- and/or postoperative training, using water reinforcement, to turn in circles (rotation) affects the behavioral symptoms induced by unilateral 6-hydroxydopamine (6-ohda)-induced da denervation of the rat substantia nigra (sn); (2) whether there was any influence of this training on the temporal pattern of recovery; and (3) whether the rotational training influences turning induced by systemic injection of dopaminergic drugs. |
1992-11-04 |
2023-08-11 |
rat |
| J H Roger. Immunohistochemical markers in rat brain: colocalization of calretinin and calbindin-D28k with tyrosine hydroxylase. Brain research. vol 587. issue 2. 1992-10-22. PMID:1356063. |
many dopaminergic cells of the substantia nigra are known to contain the calcium-binding proteins calretinin and calbindin-d28k. |
1992-10-22 |
2023-08-11 |
rat |
| G D Crawford, W D Le, R G Smith, W J Xie, E Stefani, S H Appe. A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 9. 1992-10-19. PMID:1356145. |
a novel n18tg2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. |
1992-10-19 |
2023-08-11 |
rat |
| G D Crawford, W D Le, R G Smith, W J Xie, E Stefani, S H Appe. A novel N18TG2 x mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 9. 1992-10-19. PMID:1356145. |
the cell line expresses a complex range of neural properties found in the dopaminergic neurons of the substantia nigra, and may therefore be useful elucidating further details of their cell biology. |
1992-10-19 |
2023-08-11 |
rat |
| S E Loughlin, A An, F M Lesli. Opioid receptor changes in weaver mouse striatum. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1324769. |
the dopaminergic projection from the substantia nigra to the patch and matrix compartments of the caudate-putamen undergoes a spontaneous, early postnatal degeneration in mice which carry the weaver gene. |
1992-09-29 |
2023-08-11 |
mouse |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
several lines of evidence suggest that a degeneration of dopaminergic cells in the substantia nigra produces the symptoms of parkinson's disease. |
1992-09-29 |
2023-08-11 |
Not clear |
| M Hajós, S Greenfiel. Differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511329. |
differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro. |
1992-09-29 |
2023-08-11 |
Not clear |
| M Hajós, S Greenfiel. Differential actions of acetylcholinesterase on the soma and dendrites of dopaminergic substantia nigra neurons in vitro. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1511329. |
in the substantia nigra, acetylcholinesterase (ache) has non-cholinergic action on dopaminergic neurons. |
1992-09-29 |
2023-08-11 |
Not clear |
| D Ben-Shachar, G Eshel, P Riederer, M B Youdi. Role of iron and iron chelation in dopaminergic-induced neurodegeneration: implication for Parkinson's disease. Annals of neurology. vol 32 Suppl. 1992-09-18. PMID:1510367. |
recent studies in parkinson's disease suggest that the degeneration of the nigrostriatal melanin-containing dopaminergic neurons results from toxic effects of free radicals, which are generated during dopamine metabolism in the substantia nigra (sn). |
1992-09-18 |
2023-08-11 |
rat |
| F H Gage, U J Kang, L J Fishe. Intracerebral grafting in the dopaminergic system: issues and controversy. Current opinion in neurobiology. vol 1. issue 3. 1992-08-26. PMID:1821685. |
several groups have published the clinical outcome of fetal substantia nigra implants in parkinsonian patients and studies suggest that sprouting of dopaminergic fibers in response to grafting procedures ameliorates the behavioral deficits of dopamine-depleted animals. |
1992-08-26 |
2023-08-11 |
Not clear |
| J H Carlson, S L Foot. Oscillation of interspike interval length in substantia nigra dopamine neurons: effects of nicotine and the dopaminergic D2 agonist LY 163502 on electrophysiological activity. Synapse (New York, N.Y.). vol 11. issue 3. 1992-08-24. PMID:1636152. |
oscillation of interspike interval length in substantia nigra dopamine neurons: effects of nicotine and the dopaminergic d2 agonist ly 163502 on electrophysiological activity. |
1992-08-24 |
2023-08-11 |
rat |
| W Maruyama, D Nakahara, M Ota, T Takahashi, A Takahashi, T Nagatsu, M Nao. N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1629715. |
these results indicate that around dopaminergic neurons, particularly in the substantia nigra, (r)-salsolinol was methylated into n-methyl-(r)-salsolinol, which has a chemical structure similar to that of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, the selective dopaminergic neurotoxin. |
1992-08-20 |
2023-08-11 |
rat |
| A Zuddas, G Oberto, F Vaglini, F Fascetti, F Fornai, G U Corsin. MK-801 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in primates. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1629743. |
mk-801 also attenuated dopamine depletion in the caudate and putamen and protected dopaminergic neurons in the substantia nigra from the degeneration induced by the neurotoxin. |
1992-08-20 |
2023-08-11 |
monkey |
| J J Soghomonian, M F Chessele. Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat. Synapse (New York, N.Y.). vol 11. issue 2. 1992-08-10. PMID:1626311. |
dopaminergic neurons were lesioned by unilateral injections of 6-hydroxydopamine (6-ohda) in the substantia nigra of adult rats. |
1992-08-10 |
2023-08-11 |
rat |
| H K Jiang, J Y Wan. The effects of dopamine D-1 and D-2 receptor subtype agonists on nigrostriatal opioid dynorphin and enkephalin immunostaining in 6-hydroxydopamine lesioned rats. The Chinese journal of physiology. vol 34. issue 4. 1992-08-10. PMID:1687937. |
tissue staining with specific antibodies against either dynorphin a (1-17) or [met5]-enkephalin was examined in the striatum and substantia nigra following unilateral nigrostriatal dopaminergic lesioning by the neurotoxin 6-hydroxydopamine (6-ohda). |
1992-08-10 |
2023-08-11 |
rat |
| I Mendez, K Elisevich, B Flumerfel. Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: an ultrastructural double-labeling immunocytochemical study. Brain research bulletin. vol 28. issue 4. 1992-08-05. PMID:1377584. |
substance p synaptic interactions with gabaergic and dopaminergic neurons in rat substantia nigra: an ultrastructural double-labeling immunocytochemical study. |
1992-08-05 |
2023-08-11 |
rat |
| I Mendez, K Elisevich, B Flumerfel. Substance P synaptic interactions with GABAergic and dopaminergic neurons in rat substantia nigra: an ultrastructural double-labeling immunocytochemical study. Brain research bulletin. vol 28. issue 4. 1992-08-05. PMID:1377584. |
evidence of sp-containing terminals contacting both gabaergic and dopaminergic neurons in the substantia nigra suggests a direct excitatory action upon nigral projection neurons. |
1992-08-05 |
2023-08-11 |
rat |
| F Lisovoski, C Haby, E Borrelli, C Schleef, M O Revel, C Hindelang, J Zwille. Induction of D2 dopamine receptor mRNA synthesis in a 6-hydroxydopamine parkinsonian rat model. Brain research bulletin. vol 28. issue 5. 1992-08-05. PMID:1535533. |
by injecting 6-hydroxydopamine into the pars compacta of the substantia nigra, we produced a hemiparkinsonian rat model in which there is almost complete destruction of the dopaminergic nigrostriatal pathway but sparing of the dopaminergic mesolimbic system. |
1992-08-05 |
2023-08-11 |
rat |
| M Corio, J Thibault, J Peut. Distribution of catecholaminergic and serotoninergic systems in forebrain and midbrain of the newt, Triturus alpestris (Urodela). Cell and tissue research. vol 268. issue 2. 1992-08-03. PMID:1352186. |
no dopaminergic system equivalent to the substantia nigra was revealed. |
1992-08-03 |
2023-08-11 |
Not clear |
| J Woulfe, A Beaude. Neurotensin terminals form synapses primarily with neurons lacking detectable tyrosine hydroxylase immunoreactivity in the rat substantia nigra and ventral tegmental area. The Journal of comparative neurology. vol 321. issue 1. 1992-07-30. PMID:1351897. |
a light and electron microscopic double antigen localization technique was employed to examine the fine structural relationship between neurotensin-containing axon terminals and dopaminergic neurons in the substantia nigra and ventral tegmental area of the rat. |
1992-07-30 |
2023-08-11 |
rat |