| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Woulfe, A Beaude. Neurotensin terminals form synapses primarily with neurons lacking detectable tyrosine hydroxylase immunoreactivity in the rat substantia nigra and ventral tegmental area. The Journal of comparative neurology. vol 321. issue 1. 1992-07-30. PMID:1351897. |
these results are interpreted in light of the selective association of neurotensin receptors with dopaminergic neurons in the substantia nigra and ventral tegmental area to suggest a predominantly parasynaptic mechanism of action for neurotensin in the ventral midbrain. |
1992-07-30 |
2023-08-11 |
rat |
| V M Mann, J M Cooper, D Krige, S E Daniel, A H Schapira, C D Marsde. Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain : a journal of neurology. vol 115 ( Pt 2). 1992-07-22. PMID:1606472. |
the tissue specificity of the complex i deficiency in parkinson's disease and its localization to the substantia nigra support the proposition that complex i deficiency may be directly involved in the cause of dopaminergic cell death in parkinson's disease. |
1992-07-22 |
2023-08-11 |
mouse |
| A Iacopino, S Christakos, D German, P K Sonsalla, C A Alta. Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity. Brain research. Molecular brain research. vol 13. issue 3. 1992-06-29. PMID:1317497. |
immunocytochemical characterization of the substantia nigra of the mptp-treated mice revealed that there was significant dopaminergic cell loss in this brain area after mptp treatment. |
1992-06-29 |
2023-08-11 |
mouse |
| H Nagasawa, T Araki, K Kogur. Alteration of dopamine D1 receptor in the strionigral system of the postischemic rat brain. Neuroscience letters. vol 134. issue 2. 1992-06-25. PMID:1534160. |
the present study indicates that the postischemic delayed reduction of dopamine d1 receptor sites observed in the substantia nigra is due to the degeneration of the dopaminergic nerve terminals in the strionigral system caused by the precedent ischemic damage of the ipsilateral caudate putamen. |
1992-06-25 |
2023-08-11 |
rat |
| R Arai, Y Kojima, M Geffard, K Kitahama, T Maed. Combined use of silver staining of the retrograde tracer WGAapoHRP-Au and pre-embedding immunocytochemistry for electron microscopy: demonstration of dopaminergic terminals in synaptic contact with striatal neurons projecting to the substantia nigra in the rat. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 40. issue 6. 1992-06-25. PMID:1588034. |
combined use of silver staining of the retrograde tracer wgaapohrp-au and pre-embedding immunocytochemistry for electron microscopy: demonstration of dopaminergic terminals in synaptic contact with striatal neurons projecting to the substantia nigra in the rat. |
1992-06-25 |
2023-08-11 |
rat |
| R Arai, Y Kojima, M Geffard, K Kitahama, T Maed. Combined use of silver staining of the retrograde tracer WGAapoHRP-Au and pre-embedding immunocytochemistry for electron microscopy: demonstration of dopaminergic terminals in synaptic contact with striatal neurons projecting to the substantia nigra in the rat. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 40. issue 6. 1992-06-25. PMID:1588034. |
dopaminergic terminals were demonstrated to synapse with striatal neurons projecting to the substantia nigra. |
1992-06-25 |
2023-08-11 |
rat |
| K Yamada, M Sakai, T Takeuchi, N Karasawa, N Kaneda, T Sasaoka, K Kobayashi, M Yokoyama, T Nomura, M Katsuk. Enhanced expression of human tyrosine hydroxylase in the lower brainstem of transgenic mice. Neuroscience letters. vol 134. issue 1. 1992-06-24. PMID:1687701. |
we have previously reported the distribution of human tyrosine hydroxylase (th) transgene expression in dopaminergic neurons (ventral tegmental area and substantia nigra), adrenal gland, and non-catecholaminergic neurons in the forebrain of transgenic (tg) mice. |
1992-06-24 |
2023-08-11 |
mouse |
| M Diana, G Mereu, A Mura, F Fadda, N Passino, G Gess. Low doses of gamma-hydroxybutyric acid stimulate the firing rate of dopaminergic neurons in unanesthetized rats. Brain research. vol 566. issue 1-2. 1992-06-23. PMID:1814536. |
administration of gamma-hydroxybutyric acid (ghb) at the doses of 50-400 mg/kg produced a dose-related stimulation (10-56%) of the firing rate of dopaminergic (da) neurons in the pars compacta of the substantia nigra. |
1992-06-23 |
2023-08-11 |
rat |
| R Meloni, K Gal. Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra. European journal of pharmacology. vol 209. issue 1-2. 1992-06-23. PMID:1839982. |
rats with a unilateral 6-hydroxydopamine lesion of the dopaminergic nigrostriatal pathway were examined for cocaine-induced rotational behavior 1 month after receiving transplants of fetal substantia nigra grafted over the dopamine (da)-deafferented striatum. |
1992-06-23 |
2023-08-11 |
rat |
| C R Gerfe. The neostriatal mosaic: multiple levels of compartmental organization. Trends in neurosciences. vol 15. issue 4. 1992-06-12. PMID:1374971. |
the second level segregates the cortical outputs of sublaminae of layer v between the patch and matrix compartments of the striatum, which project to the dopaminergic and gabaergic neurons in the substantia nigra, respectively. |
1992-06-12 |
2023-08-11 |
Not clear |
| J Adair, F Fillou. Effects of hypoxic-ischemic brain damage on dopaminergic markers in the neonatal rat: a regional autoradiographic analysis. Journal of child neurology. vol 7. issue 2. 1992-06-04. PMID:1533408. |
changes within dopaminergic pathways were variable, with reduction in binding being encountered mainly in components of the extrapyramidal motor system: caudate-putamen, -61%; globus pallidus, -64%; entopeduncular nucleus, -60%; and substantia nigra, -69%. |
1992-06-04 |
2023-08-11 |
rat |
| L K Srivastava, M A Morency, R K Mishr. Ontogeny of dopamine D2 receptor mRNA in rat brain. European journal of pharmacology. vol 225. issue 2. 1992-04-28. PMID:1532367. |
in situ hybridization revealed a differential developmental profile of d2 mrna for major dopaminergic regions of rat brain such as caudate putamen, nucleus accumbens, olfactory tubercle and substantia nigra. |
1992-04-28 |
2023-08-11 |
rat |
| H Dabadie, M Geffard, M C Charrier, D Locuratolo, C Berrier, J C Jacques. First characterization of 6-hydroxytryptamine in the rat midbrain by using specific antibodies. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1372343. |
in the dopaminergic region, 6-ht immunoreactivity was noted in the substantia nigra but was particularly intense in the red nuclei, where it seems to be localized in the magnocellular division in the form of large 6-ht neurons. |
1992-04-17 |
2023-08-11 |
rat |
| J G Richards, J Saura, J Ulrich, M Da Prad. Molecular neuroanatomy of monoamine oxidases in human brainstem. Psychopharmacology. vol 106 Suppl. 1992-04-15. PMID:1546134. |
in the substantia nigra, mao-b was more abundant than mao-a; the former was localized in the reticular zone and the latter in the compact zone (where melanin-containing dopaminergic neurons are found). |
1992-04-15 |
2023-08-11 |
human |
| D J Sirinathsinghji, A Kupsch, E Mayer, M Zivin, D Pufal, W H Oerte. Cellular localization of tyrosine hydroxylase mRNA and cholecystokinin mRNA-containing cells in the ventral mesencephalon of the common marmoset: effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain research. Molecular brain research. vol 12. issue 1-3. 1992-04-13. PMID:1347634. |
in situ hybridization histochemistry was used to localize tyrosine hydroxylase (th) mrna and cholecystokinin (cck) mrna-expressing cells in the ventral mesencephalon of the common marmoset (callithrix jacchus) and to examine the effects of the dopaminergic (da) neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on these two populations of neurons in the pars compacta of the substantia nigra (snc) and ventral tegmental area (vta). |
1992-04-13 |
2023-08-11 |
human |
| M J Millan, K Bervoets, M Mavridi. The serotonin (5-HT)1A agonist, LY 165,163, induces contralateral rotation in unilateral substantia nigra-lesioned rats via dopamine receptors. Neuroscience letters. vol 130. issue 2. 1992-04-08. PMID:1795876. |
thus, in this study, we examined its ability to induce rotation in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra, an in vivo model of dopaminergic activity. |
1992-04-08 |
2023-08-11 |
rat |
| W C Graham, D R Hill, G N Woodruff, M A Sambrook, A R Crossma. Reduction of [125I]Bolton Hunter CCK8 and [3H]MK-329 (devazepide) binding to CCK receptors in the substantia nigra/VTA complex and its forebrain projection areas following MPTP-induced hemi-parkinsonism in the monkey. Neuroscience letters. vol 131. issue 1. 1992-04-02. PMID:1791971. |
these results indicate that cck-a receptors may be located on dopaminergic cells within the substantia nigra, which are lost in the parkinsonian brain, and may also be present on dopaminergic terminals within restricted regions of nigral/ventral tegmental area projection sites. |
1992-04-02 |
2023-08-11 |
monkey |
| J F Chen, B Weis. Ontogenetic expression of D2 dopamine receptor mRNA in rat corpus striatum. Brain research. Developmental brain research. vol 63. issue 1-2. 1992-04-01. PMID:1665109. |
these results suggest that the postnatal development of the d2r mrna in rat striatum correlates well with the ontogeny of the d2 dopamine receptor, that the developmental expression of the d2r mrna is highly associated with the maturation and differentiation of striatal neurons, and that the development of the d2r mrna in rat striatum, unlike that of proenkephalin mrna, can proceed even with reduced dopaminergic afferent input from the substantia nigra. |
1992-04-01 |
2023-08-11 |
rat |
| L A Arbogast, J L Voog. Ontogeny of tyrosine hydroxylase mRNA signal levels in central dopaminergic neurons: development of a gender difference in the arcuate nuclei. Brain research. Developmental brain research. vol 63. issue 1-2. 1992-04-01. PMID:1686424. |
th mrna signal levels increased between days 5 and 15 of age in dopaminergic perikarya in the zona incerta and the substantia nigra of both female and male rats. |
1992-04-01 |
2023-08-11 |
rat |
| J S McKenzie, A D Shafton, C A Stewar. Intrastriatal dopaminergic agents, muscarinic stimulation, and GABA antagonism compared for rotation responses in rats. Behavioural brain research. vol 45. issue 2. 1992-03-27. PMID:1686398. |
we tested the common hypothesis that rotation on systemic injection of dopaminergic agents in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra is attributable to unequal stimulation of dopamine receptors between the two striata. |
1992-03-27 |
2023-08-11 |
rat |