| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcello Serra, Anna Di Maio, Valentina Bassareo, Tommaso Nuzzo, Francesco Errico, Federica Servillo, Mario Capasso, Pathik Parekh, Qin Li, Marie-Laure Thiolat, Erwan Bezard, Paolo Calabresi, David Sulzer, Manolo Carta, Micaela Morelli, Alessandro Usiell. Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. Neurobiology of disease. 2023-07-14. PMID:37451474. |
perturbation of serine enantiomers homeostasis in the striatum of mptp-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. |
2023-07-14 |
2023-08-14 |
mouse |
| Marcello Serra, Anna Di Maio, Valentina Bassareo, Tommaso Nuzzo, Francesco Errico, Federica Servillo, Mario Capasso, Pathik Parekh, Qin Li, Marie-Laure Thiolat, Erwan Bezard, Paolo Calabresi, David Sulzer, Manolo Carta, Micaela Morelli, Alessandro Usiell. Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain degeneration. Neurobiology of disease. 2023-07-14. PMID:37451474. |
conversely, concentrations of d-serine and l-serine, as well as asct1 and gapdh expression were unaffected in the striatum of mptpp-treated mice, which showed only mild dopaminergic degeneration (⁓30%). |
2023-07-14 |
2023-08-14 |
mouse |
| Harry Costello, Anette-Eleonore Schrag, Robert Howard, Jonathan P Roise. Dissociable effects of dopaminergic medications on depression symptom dimensions in Parkinson's disease. medRxiv : the preprint server for health sciences. 2023-07-10. PMID:37425947. |
loss of dopaminergic innervation of the striatum is associated with emergence of motivational symptoms in pd, and mood fluctuations correlate with dopamine availability. |
2023-07-10 |
2023-08-14 |
Not clear |
| Xu Cao, Zhong-Rui Du, Xin Liu, Xiong Wang, Chong Li, Sai-Nan Zhou, Jia-Rui Liu, Ping-Yi Xu, Jun-Li Ye, Qing Zhao, Fang Zhao, Ka-Hing Wong, Xiao-Li Don. Low and high doses of oral maslinic acid protect against Parkinson's disease via distinct gut microbiota-related mechanisms. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-07. PMID:37418977. |
the present study found both low and high dose ma treatment significantly prevented dopaminergic neuronal loss in a classical chronic pd mouse model by ameliorating motor functions and improving tyrosine hydroxylase expressions in the substantia nigra pars compacta (snpc) and increasing dopamine and its metabolite homovanillic acid levels in the striatum. |
2023-07-07 |
2023-08-14 |
mouse |
| Jihye Yoo, In Kook Chu. Extrastriatal Accumulation of 18F-FP-CIT at Cerebral Infarction in a Patient With Suspected Parkinson Disease. Clinical nuclear medicine. 2023-06-19. PMID:37335267. |
18f-fp-cit pet/ct is a useful diagnostic tool for differentiating between idiopathic parkinson disease and atypical parkinson syndrome by visualizing the striatum, where the nerve endings of nigrostriatal dopaminergic neurons are located. |
2023-06-19 |
2023-08-14 |
Not clear |
| Sahar Mani, Houda Bouchnak, Solène Pradeloux, Jamil Kraiem, Denis Soulet, Imed Messaoud. 3-aminohydantoin derivate as a promising scaffold in dopaminergic neuroprotection and neurorescue in the in vivo and in vitro 6-hydroxydopamine models of Parkinson's disease. Clinical and experimental pharmacology & physiology. 2023-06-18. PMID:37331719. |
most interestingly, phah restored 6-ohda-induced dopaminergic neurodegeneration in the substantia nigra and striatum and ameliorated 6-ohda-induced oxidative stress in the rat brain. |
2023-06-18 |
2023-08-14 |
rat |
| Carmen Costas-Ferreira, Rafael Durán, Lilian Ferreira Far. Neurotoxic effects of exposure to glyphosate in rat striatum: Effects and mechanisms of action on dopaminergic neurotransmission. Pesticide biochemistry and physiology. vol 193. 2023-05-29. PMID:37248010. |
neurotoxic effects of exposure to glyphosate in rat striatum: effects and mechanisms of action on dopaminergic neurotransmission. |
2023-05-29 |
2023-08-14 |
rat |
| Carmen Costas-Ferreira, Rafael Durán, Lilian Ferreira Far. Neurotoxic effects of exposure to glyphosate in rat striatum: Effects and mechanisms of action on dopaminergic neurotransmission. Pesticide biochemistry and physiology. vol 193. 2023-05-29. PMID:37248010. |
the main objective of this study was to evaluate the effects and possible mechanisms of action of glyphosate and a glyphosate-based herbicide (gbh) on dopaminergic neurotransmission in the rat striatum. |
2023-05-29 |
2023-08-14 |
rat |
| Chenmeng Qiao, Guyu Niu, Weijiang Zhao, Wei Quan, Yu Zhou, Meixuan Zhang, Ting Li, Shengyang Zhou, Wenyan Huang, Liping Zhao, Jian Wu, Chun Cui, Yanqin She. RIPK1-Induced A1 Reactive Astrocytes in Brain in MPTP-Treated Murine Model of Parkinson's Disease. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239205. |
it also increased striatal th expression, rescue the loss of dopaminergic neurons, and reduce activation of astrocytes in the striatum of pd mice. |
2023-05-27 |
2023-08-14 |
mouse |
| Macarena González-Portilla, Susana Mellado, Sandra Montagud-Romero, Fernando Rodríguez de Fonseca, María Pascual, Marta Rodríguez-Aria. Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum. Behavioral and brain functions : BBF. vol 19. issue 1. 2023-05-24. PMID:37226219. |
oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum. |
2023-05-24 |
2023-08-14 |
mouse |
| Alireza Rouzitalab, Chadwick B Boulay, Adam J Sach. Volitional Control of Beta Activities in Parkinson's Disease Patients. Brain research. 2023-05-08. PMID:37156320. |
patients diagnosed with parkinson's disease (pd) have difficulty initiating and executing movements due to an acquired imbalance of the basal ganglia thalamocortical circuit secondary to loss of dopaminergic input into the striatum. |
2023-05-08 |
2023-08-14 |
Not clear |
| Delaney L Davis, Daniel B Metzger, Philip H Vann, Jessica M Wong, Ritu A Shetty, Michael J Forster, Nathalie Sumie. Effects of chronic methamphetamine exposure on rewarding behavior and neurodegeneration markers in adult mice. Psychopharmacology. 2023-05-01. PMID:37127834. |
the midbrain and striatum, regions involved in reward circuit, were assessed for markers associated with neurotoxicity, dopaminergic function, neuroinflammation and epigenetic changes after behavioral testing.previous exposure to chronic meth did not have significant short-term effects on cpp response but led to a decreased cpp response in 10-month-old females. |
2023-05-01 |
2023-08-14 |
mouse |
| Marianne Oldehinkel, Jeggan Tiego, Kristina Sabaroedin, Sidhant Chopra, Shona M Francey, Brian O'Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Christos Pantelis, Stephen J Wood, Patrick McGorry, Mark A Bellgrove, Alex Fornit. Gradients of striatal function in antipsychotic-free first-episode psychosis and schizotypy. Translational psychiatry. vol 13. issue 1. 2023-04-18. PMID:37072388. |
here, we investigated two of these functional connectivity modes, previously associated with variations in the topographic patterning of cortico-striatal connectivity (first-order gradient), and dopaminergic innervation of the striatum (second-order gradient), and assessed continuities in striatal function from subclinical to clinical domains. |
2023-04-18 |
2023-08-14 |
Not clear |
| Cláudia Saraiva, Jéssica Lopes-Nunes, Marta Esteves, Tiago Santos, Ana Vale, Ana Clara Cristóvão, Raquel Ferreira, Liliana Bernardin. CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival. Molecular neurobiology. 2023-04-15. PMID:37060501. |
herein, we showed that ctbp1 and ctbp2 are expressed in neurons, dopaminergic neurons, astrocytes, and microglia in the substantia nigra (sn) and striatum of adult mice. |
2023-04-15 |
2023-08-14 |
mouse |
| Anima Kumari, Anugya Srivastava, Pankaj Jagdale, Anjaneya Ayanur, Vinay Kumar Khann. Lambda-cyhalothrin Enhances Inflammation in Nigrostriatal Region in Rats:Regulatory Role of NF-κβ and JAK-STAT Signaling. Neurotoxicology. 2023-04-15. PMID:37060950. |
exposure of rats to lct also caused alteration in the levelsof heat shock protein 60 (hsp60) and mrna expression of toll-like receptors(tlr2 and tlr4) in the substantia nigra and corpus striatum.an increase in the phosphorylation of key proteins involved in nf-kβ (p65, iκβ, ikkα, ikkβ)signalingand stat1 and stat3 and alteration in the protein levels of jak1 and jak2 were prominent in lct-treated rats.histological studies revealed damage of dopaminergic neurons and reactive gliosis as evidenced by the presence of darkly stained pyknotic neurons anddecrease in nisslsubstance and an increase in infiltration of immune cells both in substantia nigra and corpus striatum of lct-treated rats. |
2023-04-15 |
2023-08-14 |
rat |
| Anima Kumari, Anugya Srivastava, Pankaj Jagdale, Anjaneya Ayanur, Vinay Kumar Khann. Lambda-cyhalothrin Enhances Inflammation in Nigrostriatal Region in Rats:Regulatory Role of NF-κβ and JAK-STAT Signaling. Neurotoxicology. 2023-04-15. PMID:37060950. |
the results exhibit that lct may damage dopaminergic neurons in the substantia nigra and corpus striatum by inducing inflammation as a result of stimulation of neuroglial cells involving activation of nf-κβ and jak/stat signaling. |
2023-04-15 |
2023-08-14 |
rat |
| Michał Szulc, Radosław Kujawski, Amanda Pacholak, Marta Poprawska, Kamila Czora-Poczwardowska, Bogna Geppert, Przemysław Ł Mikołajcza. Cannabidiol as a Modulator of the Development of Alcohol Tolerance in Rats. Nutrients. vol 15. issue 7. 2023-04-13. PMID:37049542. |
in the prefrontal cortex, hippocampus, and striatum, the cannabinoid (cb1r and cb2r) and dopaminergic (drd1, drd2, drd4, drd5) receptors' mrna level changes were analyzed using the quantitative rt-pcr method. |
2023-04-13 |
2023-08-14 |
rat |
| R Basanisi, K Marche, E Combrisson, P Apicella, A Brovell. Beta oscillations in monkey striatum encode reward prediction error signals. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-04-04. PMID:37015808. |
rpe signals are encoded in the neural activity of multiple brain areas, such as midbrain dopaminergic neurons, prefrontal cortex and striatum. |
2023-04-04 |
2023-08-14 |
monkey |
| Javier Villadiego, Roberto García-Swinburn, Diego García-González, Rafael Lebrón-Galán, Verónica Murcia-Belmonte, Ernesto García-Roldán, Nela Suárez-Luna, Cristina Nombela, Miguel Marchena, Fernando de Castro, Juan José Toledo-Ara. Extracellular matrix protein anosmin-1 overexpression alters dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in a MPTP model of Parkinson's disease. Brain structure & function. 2023-03-30. PMID:36995433. |
we found that a1 overexpression increases the number of dopaminergic substantia nigra pars compacta (snpc) neurons and alters the striosome/matrix organization of the striatum. |
2023-03-30 |
2023-08-14 |
Not clear |
| Srinivasa Subramaniam, Siddaraju Boregowd. Curbing Rhes Actions: Mechanism-Based Molecular Target for Huntington's Disease and Tauopathies. CNS & neurological disorders drug targets. 2023-03-24. PMID:36959146. |
rhes, an atypical small gtpase with a sumo (small ubiquitin-like modifier) e3-ligase activity, modulates biological processes such as dopaminergic transmission, alters gene expression, and acts as an inhibitor of motor stimuli in the brain striatum. |
2023-03-24 |
2023-08-14 |
human |