| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ko Miyoshi, Kyosuke Kasahara, Shinki Murakami, Mika Takeshima, Natsuko Kumamoto, Asako Sato, Ikuko Miyazaki, Shinsuke Matsuzaki, Toshikuni Sasaoka, Taiichi Katayama, Masato Asanum. Lack of dopaminergic inputs elongates the primary cilia of striatal neurons. PloS one. vol 9. issue 5. 2015-06-15. PMID:24830745. |
here we investigated the effects of dopaminergic inputs loss on the architecture of neuronal primary cilia in the rodent striatum, a brain region that receives major dopaminergic projections from the midbrain. |
2015-06-15 |
2023-08-13 |
mouse |
| Carsten Eggers, Frank Schwartz, David J Pedrosa, Lutz Kracht, Lars Timmerman. Parkinson's disease subtypes show a specific link between dopaminergic and glucose metabolism in the striatum. PloS one. vol 9. issue 5. 2015-06-15. PMID:24848641. |
parkinson's disease subtypes show a specific link between dopaminergic and glucose metabolism in the striatum. |
2015-06-15 |
2023-08-13 |
Not clear |
| KyoungWon Baik, Jungho Cha, Jee Hyun Ham, Gwang-Min Baek, Mun Kyung Sunwoo, Jin Yong Hong, Na-Young Shin, Jae Seung Kim, Jong-Min Lee, Seung-Koo Lee, Young Ho Sohn, Phil Hyu Le. Dopaminergic modulation of resting-state functional connectivity in de novo patients with Parkinson's disease. Human brain mapping. vol 35. issue 11. 2015-06-15. PMID:24938993. |
parkinson's disease (pd) is characterized by degenerative changes of nigral dopamine neurons, resulting in the dopaminergic denervation of the striatum. |
2015-06-15 |
2023-08-13 |
Not clear |
| Alessandro Tozzi, Antonio de Iure, Michela Tantucci, Valentina Durante, Ana Quiroga-Varela, Carmela Giampà, Michela Di Mauro, Petra Mazzocchetti, Cinzia Costa, Massimiliano Di Filippo, Silvarosa Grassi, Vito Enrico Pettorossi, Paolo Calabres. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Frontiers in cellular neuroscience. vol 9. 2015-06-15. PMID:26074768. |
endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. |
2015-06-15 |
2023-08-13 |
rat |
| Mauricio Peña Cunha, Maria D Martín-de-Saavedra, Alejandro Romero, Javier Egea, Fabiana K Ludka, Carla I Tasca, Marcelo Farina, Ana Lúcia S Rodrigues, Manuela G Lópe. Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model. ASN neuro. vol 6. issue 6. 2015-06-12. PMID:25424428. |
in conclusion, creatine and pcr minimize oxidative stress in striatum to afford neuroprotection of dopaminergic neurons. |
2015-06-12 |
2023-08-13 |
rat |
| Ye Lee Jun, Chang-Hwan Bae, Dongsoo Kim, Sungtae Koo, Seungtae Ki. Korean Red Ginseng protects dopaminergic neurons by suppressing the cleavage of p35 to p25 in a Parkinson's disease mouse model. Journal of ginseng research. vol 39. issue 2. 2015-06-05. PMID:26045688. |
the present study investigated a possible role of korean red ginseng (krg) in suppressing dopaminergic neuronal cell death and the cleavage of p35 to p25 in the substantia nigra (sn) and striatum (st) using a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced parkinson's disease mouse model. |
2015-06-05 |
2023-08-13 |
mouse |
| Tertia D Purves-Tyson, Samantha J Owens, Kay L Double, Reena Desai, David J Handelsman, Cynthia Shannon Weicker. Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway. PloS one. vol 9. issue 3. 2015-05-29. PMID:24618531. |
gene expression changes in the dopaminergic cell body region may serve to modulate both dendritic dopamine feedback inhibition and reuptake in the dopaminergic somatodendritic field as well as dopamine release and re-uptake dynamics at the presynaptic terminals in the striatum. |
2015-05-29 |
2023-08-12 |
rat |
| Kathrin Koch, Oana Georgiana Rus, Tim Jonas Reeß, Claudia Schachtzabel, Gerd Wagner, C Christoph Schultz, Christian Sorg, Ralf G M Schlösse. Functional connectivity and grey matter volume of the striatum in schizophrenia. The British journal of psychiatry : the journal of mental science. vol 205. issue 3. 2015-05-29. PMID:25012683. |
alterations in the dopaminergic reward system, predominantly the striatum, constitute core characteristics of schizophrenia. |
2015-05-29 |
2023-08-13 |
Not clear |
| Dustin R Wakeman, Stephanie Weiss, John R Sladek, John D Elsworth, Brian Bauereis, Csaba Leranth, Patrick J Hurley, Robert H Roth, D Eugene Redmon. Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates. Cell transplantation. vol 23. issue 8. 2015-05-27. PMID:23562290. |
expression of the dopaminergic marker tyrosine hydroxylase was not maintained in hesc-derived neural grafts in either the striatum or substantia nigra, despite a neuronal morphology and expression of β-iii-tubulin. |
2015-05-27 |
2023-08-12 |
human |
| Reka Daniel, Stefan Pollman. A universal role of the ventral striatum in reward-based learning: evidence from human studies. Neurobiology of learning and memory. vol 114. 2015-05-22. PMID:24825620. |
while results from electrophysiological recordings in humans are sparse, evidence linking dopaminergic activity to the metabolic signal recorded from the midbrain and striatum with functional magnetic resonance imaging (fmri) is available. |
2015-05-22 |
2023-08-13 |
human |
| Jing-Wei Zhao, Sean C Dyson, Christina Kriegel, Pam Tyers, Xiaoling He, Tarek M Fahmy, Su M Metcalfe, Roger A Barke. Modelling of a targeted nanotherapeutic 'stroma' to deliver the cytokine LIF, or XAV939, a potent inhibitor of Wnt-β-catenin signalling, for use in human fetal dopaminergic grafts in Parkinson's disease. Disease models & mechanisms. vol 7. issue 10. 2015-05-20. PMID:25085990. |
using leukaemia inhibitory factor (lif) - a proneural, reparative cytokine - formulated as target-specific poly(lactic-co-glycolic acid) (plga) nano-particles (lif-nano-stroma), we discovered that attachment of lif-nano-stroma to freshly isolated fetal dopaminergic cells improved their survival fourfold: furthermore, in vivo, the number of surviving human fetal dopaminergic cells tended to be higher at 3 months after grafting into the striatum of nude rats, compared with controls treated with empty nanoparticles. |
2015-05-20 |
2023-08-13 |
human |
| Masanori Itakura, Tomoko Kohda, Takeya Kubo, Yuko Semi, Kazuhiro Nishiyama, Yasu-Taka Azuma, Hidemitsu Nakajima, Shunji Kozaki, Tadayoshi Takeuch. Botulinum neurotoxin type A subtype 2 confers greater safety than subtype 1 in a rat Parkinson's disease model. The Journal of veterinary medical science. vol 76. issue 8. 2015-05-14. PMID:24849052. |
we first confirmed that intrastriatal treatments of both bont/as had no-effect on dopaminergic terminals in the striatum. |
2015-05-14 |
2023-08-13 |
rat |
| Jie Li, Terence Duarte, Arif Kocabas, Melissa Works, Susan K McConnell, Mary A Hyne. Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum. Molecular and cellular neurosciences. vol 61. 2015-04-15. PMID:24867253. |
evidence for topographic guidance of dopaminergic axons by differential netrin-1 expression in the striatum. |
2015-04-15 |
2023-08-13 |
mouse |
| Jie Li, Terence Duarte, Arif Kocabas, Melissa Works, Susan K McConnell, Mary A Hyne. Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum. Molecular and cellular neurosciences. vol 61. 2015-04-15. PMID:24867253. |
there are two main subgroups of midbrain dopaminergic (da) neurons: the more medially located ventral tegmental area (vta) da neurons, which have axons that innervate the ventral-lateral (vl) striatum, and the more laterally located substantia nigra (sn) da neurons, which preferentially degenerate in parkinson's disease (pd) and have axons that project to the dorsal-medial (dm) striatum. |
2015-04-15 |
2023-08-13 |
mouse |
| Álvaro García-Avilés, Héctor Albert-Gascó, Isabel Arnal-Vicente, Ebtisam Elhajj, Julio Sanjuan-Arias, Ana María Sanchez-Perez, Francisco Olucha-Bordona. Acute oral administration of low doses of methylphenidate targets calretinin neurons in the rat septal area. Frontiers in neuroanatomy. vol 9. 2015-04-08. PMID:25852493. |
we analyzed dopaminergic areas such as nucleus accumbens and striatum, and found that only 5 mg/kg induced c-fos levels increase. |
2015-04-08 |
2023-08-13 |
rat |
| Jorge Cancela, Matteo Pastorino, Maria T Arredondo, Konstantina S Nikita, Federico Villagra, Maria A Pasto. Feasibility study of a wearable system based on a wireless body area network for gait assessment in Parkinson's disease patients. Sensors (Basel, Switzerland). vol 14. issue 3. 2015-04-06. PMID:24608005. |
the dopaminergic denervation of the striatum, due to substantia nigra neuronal loss, compromises the speed, the automatism and smoothness of movements of pd patients. |
2015-04-06 |
2023-08-12 |
Not clear |
| Guoshuai Feng, Zhijian Zhang, Qingqing Bao, Zaijun Zhang, Libing Zhou, Jie Jiang, Sha L. Protective effect of chinonin in MPTP-induced C57BL/6 mouse model of Parkinson's disease. Biological & pharmaceutical bulletin. vol 37. issue 8. 2015-04-06. PMID:24871044. |
consistently, chinonin reduced loss of dopaminergic neurons in the substantia nigra and prevented depletion of dopamine and its metabolites 3-methoxy-4-hydroxy-phenylacetic acid and homovanillic acid in the striatum of mice. |
2015-04-06 |
2023-08-13 |
mouse |
| Anu G Nair, Omar Gutierrez-Arenas, Olivia Eriksson, Alexandra Jauhiainen, Kim T Blackwell, Jeanette H Kotalesk. Modeling intracellular signaling underlying striatal function in health and disease. Progress in molecular biology and translational science. vol 123. 2015-04-02. PMID:24560149. |
striatum, which is the input nucleus of the basal ganglia, integrates cortical and thalamic glutamatergic inputs with dopaminergic afferents from the substantia nigra pars compacta. |
2015-04-02 |
2023-08-12 |
Not clear |
| b' S\\xc5\\x82awomir W\\xc3\\xb3jcik, Jan Henryk Spodnik, Edyta Spodnik, Jerzy Dziewi\\xc4\\x85tkowski, Janusz Mory\\xc5\\x9. Nigrostriatal pathway degeneration in rats after intraperitoneal administration of proteasome inhibitor MG-132. Folia neuropathologica. vol 52. issue 1. 2015-04-02. PMID:24729342.' |
this loss was accompanied by a corresponding decrease (8%) of density of dopaminergic terminals in dorsolateral striatum. |
2015-04-02 |
2023-08-13 |
rat |
| Daniel Rial, Fabrício A Pamplona, Eduardo L G Moreira, Karin M Moreira, Débora Hipolide, Diana I Rodrigues, Patrícia A Dombrowski, Claudio Da Cunha, Paula Agostinho, Reinaldo N Takahashi, Roger Walz, Rodrigo A Cunha, Rui D Predige. Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system. The European journal of neuroscience. vol 40. issue 3. 2015-03-30. PMID:24766164. |
prp(c) was found to co-localize with dopaminergic neurons and in dopaminergic synapses in the striatum. |
2015-03-30 |
2023-08-13 |
mouse |