| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liang Tan, Hongfei Ge, Jun Tang, Chuhua Fu, Wangsheng Duanmu, Yujie Chen, Rong Hu, Jianfeng Sui, Xin Liu, Hua Fen. Amantadine preserves dopamine level and attenuates depression-like behavior induced by traumatic brain injury in rats. Behavioural brain research. vol 279. 2015-08-20. PMID:25447294. |
the results showed that amantadine therapy could significantly ameliorate the depression-like behavior, improving the da level in the striatum and decreasing the degeneration and apoptosis of dopaminergic neurons in the sn. |
2015-08-20 |
2023-08-13 |
rat |
| Liang Tan, Hongfei Ge, Jun Tang, Chuhua Fu, Wangsheng Duanmu, Yujie Chen, Rong Hu, Jianfeng Sui, Xin Liu, Hua Fen. Amantadine preserves dopamine level and attenuates depression-like behavior induced by traumatic brain injury in rats. Behavioural brain research. vol 279. 2015-08-20. PMID:25447294. |
the results indicated that the anti-depression effect may result from the increase of extracellular da concentration in the striatum and/or the indirect neuroprotection on the dopaminergic neurons in the sn. |
2015-08-20 |
2023-08-13 |
rat |
| Durga Praveen Meka, Anne Kathrin Müller-Rischart, Prakash Nidadavolu, Behnam Mohammadi, Elisa Motori, Srinivas Kumar Ponna, Helia Aboutalebi, Mahmoud Bassal, Anil Annamneedi, Barbara Finckh, Margit Miesbauer, Natalie Rotermund, Christian Lohr, Jörg Tatzelt, Konstanze F Winklhofer, Edgar R Krame. Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. The Journal of clinical investigation. vol 125. issue 5. 2015-08-17. PMID:25822020. |
taken together, these observations indicate that parkin and the ret signaling cascade converge to control mitochondrial integrity and thereby properly maintain substantia nigra pars compacta dopaminergic neurons and their innervation in the striatum. |
2015-08-17 |
2023-08-13 |
mouse |
| Damian M Herz, Brian N Haagensen, Mark S Christensen, Kristoffer H Madsen, James B Rowe, Annemette Løkkegaard, Hartwig R Siebne. Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain : a journal of neurology. vol 138. issue Pt 6. 2015-08-07. PMID:25882651. |
dopaminergic signalling in the striatum contributes to reinforcement of actions and motivational enhancement of motor vigour. |
2015-08-07 |
2023-08-13 |
Not clear |
| Damian M Herz, Brian N Haagensen, Mark S Christensen, Kristoffer H Madsen, James B Rowe, Annemette Løkkegaard, Hartwig R Siebne. Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain : a journal of neurology. vol 138. issue Pt 6. 2015-08-07. PMID:25882651. |
parkinson's disease leads to progressive dopaminergic denervation of the striatum, impairing the function of cortico-basal ganglia networks. |
2015-08-07 |
2023-08-13 |
Not clear |
| Joëlle Nader, Cinzia Rapino, Benjamin Gennequin, Francois Chavant, Maureen Francheteau, Alexandros Makriyannis, Andrea Duranti, Mauro Maccarrone, Marcello Solinas, Nathalie Thirie. Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. Neuropharmacology. vol 87. 2015-08-04. PMID:24709540. |
prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of cb2 receptors. |
2015-08-04 |
2023-08-13 |
Not clear |
| Dimitra Terzi, Sevasti Gaspari, Lefteris Manouras, Giannina Descalzi, Vassiliki Mitsi, Venetia Zachario. RGS9-2 modulates sensory and mood related symptoms of neuropathic pain. Neurobiology of learning and memory. vol 115. 2015-08-04. PMID:25150149. |
the signal transduction modulator rgs9-2 (regulator of g protein signaling 9-2) plays a key role in dopaminergic and opioidergic transmission in the striatum. |
2015-08-04 |
2023-08-13 |
mouse |
| Candan Depboylu, Martin Klietz, Lukas Maurer, Wolfgang H Oertel, Kazuto Kobayashi, Eberhard Weihe, Günter U Höglinger, Martin K-H Schäfe. Transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25451178. |
transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation. |
2015-07-31 |
2023-08-13 |
mouse |
| Gael Le Douaron, Fanny Schmidt, Majid Amar, Hanane Kadar, Lucila Debortoli, Alexandra Latini, Blandine Séon-Méniel, Laurent Ferrié, Patrick Pierre Michel, David Touboul, Alain Brunelle, Rita Raisman-Vozari, Bruno Figadèr. Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease. European journal of medicinal chemistry. vol 89. 2015-07-24. PMID:25462259. |
parkinson disease is a neurodegenerative disorder of aging, characterized by disabling motor symptoms resulting from the loss of midbrain dopaminergic neurons and the decrease of dopamine in the striatum. |
2015-07-24 |
2023-08-13 |
mouse |
| Andrea Lebeña, Oscar Vegas, Eneritz Gómez-Lázaro, Amaia Arregi, Larraitz Garmendia, Garikoitz Beitia, Arantza Azpiro. Melanoma tumors alter proinflammatory cytokine production and monoamine brain function, and induce depressive-like behavior in male mice. Behavioural brain research. vol 272. 2015-07-16. PMID:24995613. |
these increases corresponded with a decrease in dopaminergic activity in the striatum and a decrease in serotonin turnover in the prefrontal cortex. |
2015-07-16 |
2023-08-13 |
mouse |
| Peter J Clark, Parsa R Ghasem, Agnieszka Mika, Heidi E Day, Jonathan J Herrera, Benjamin N Greenwood, Monika Fleshne. Wheel running alters patterns of uncontrollable stress-induced cfos mRNA expression in rat dorsal striatum direct and indirect pathways: A possible role for plasticity in adenosine receptors. Behavioural brain research. vol 272. 2015-07-16. PMID:25017571. |
emerging evidence indicates that adenosine is a major regulator of striatum activity, in part, through the antagonistic modulation of dopaminergic function. |
2015-07-16 |
2023-08-13 |
rat |
| Yi Zhang, Weiren Dong, Suiqun Guo, Shu Zhao, Suifen He, Lihua Zhang, Yinjuan Tang, Haihong Wan. Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 12. 2015-07-09. PMID:25030123. |
parkinson disease (pd) is a progressive neurodegenerative disorder in which the nigrostriatal pathway, consisting of dopaminergic neuronal projections from the substantia nigra to the striatum, degenerates. |
2015-07-09 |
2023-08-13 |
rat |
| Chunli Chen, Haiping Zheng, Li Yang, Zhiping H. Chorea-ballism associated with ketotic hyperglycemia. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 12. 2015-07-09. PMID:25262066. |
the mechanisms of the disease are unclear, although the gaba theory, cerebrovascular insufficiency, and alterations of dopaminergic activity in the striatum might play important roles. |
2015-07-09 |
2023-08-13 |
Not clear |
| Mats Julius Stensrud, Maja Puchades, Vidar Gunderse. GABA is localized in dopaminergic synaptic vesicles in the rodent striatum. Brain structure & function. vol 219. issue 6. 2015-07-07. PMID:23851655. |
gaba is localized in dopaminergic synaptic vesicles in the rodent striatum. |
2015-07-07 |
2023-08-12 |
Not clear |
| Signe Düring, Birte Y Glenthøj, Gitte Saltoft Andersen, Bob Oranj. Effects of dopamine D2/D3 blockade on human sensory and sensorimotor gating in initially antipsychotic-naive, first-episode schizophrenia patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:24954063. |
it has been suggested that psychophysiological measures of sensory and sensorimotor gating, p50 gating and prepulse inhibition of the startle reflex (ppi), underlie core features of schizophrenia and are linked to dopaminergic pathways in the striatum and prefrontal cortex. |
2015-07-07 |
2023-08-13 |
human |
| Sarah Iqbal, Shannon Howard, Philip V LoGrass. Serum- and Glucocorticoid-Inducible Kinase 1 Confers Protection in Cell-Based and in In Vivo Neurotoxin Models via the c-Jun N-Terminal Kinase Signaling Pathway. Molecular and cellular biology. vol 35. issue 11. 2015-07-07. PMID:25825522. |
to investigate the effect of sgk1 overexpression in vivo, sgk1-expressing adenovirus was injected into the striatum of mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, and protection of dopaminergic neurons was quantitatively assessed by tyrosine hydroxylase immunohistochemistry. |
2015-07-07 |
2023-08-13 |
mouse |
| Christina Krabbe, Sara Thornby Bak, Pia Jensen, Christian von Linstow, Alberto Martínez Serrano, Claus Hansen, Morten Meye. Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin. PloS one. vol 9. issue 5. 2015-06-23. PMID:24788190. |
our data may reflect differences in dopaminergic differentiation capacity and region-specific requirements of nscs, with the dopamine-depleted striatum cultured at low oxygen offering an attractive micro-environment for midbrain nscs. |
2015-06-23 |
2023-08-13 |
mouse |
| Stéphane Lehéricy, Eric Bardinet, Cyril Poupon, Marie Vidailhet, Chantal Françoi. 7 Tesla magnetic resonance imaging: a closer look at substantia nigra anatomy in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 29. issue 13. 2015-06-22. PMID:25308960. |
dopaminergic denervation is commonly imaged using radiotracer imaging in target structures such as the striatum. |
2015-06-22 |
2023-08-13 |
human |
| Candan Depboylu, Thomas W Rösler, Anderson de Andrade, Wolfgang H Oertel, Günter U Höglinge. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease. Journal of neurochemistry. vol 133. issue 4. 2015-06-18. PMID:25581060. |
however, nrg1β1 did not reverse mptp-induced decrease in dopamine levels and dopaminergic fibers in the striatum. |
2015-06-18 |
2023-08-13 |
mouse |
| Cody A Siciliano, Erin S Calipari, Verginia C Cuzon Carlson, Christa M Helms, David M Lovinger, Kathleen A Grant, Sara R Jone. Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 15. 2015-06-18. PMID:25878269. |
the dopaminergic projections from the ventral midbrain to the striatum have long been implicated in mediating motivated behaviors and addiction. |
2015-06-18 |
2023-08-13 |
Not clear |