| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Terri K Wood, Kieran W McDermott, Aideen M Sulliva. Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. Journal of neuroscience research. vol 80. issue 6. 2005-08-09. PMID:15880784. |
the possible involvement of astroglia in the dopaminergic neurotrophic effect induced by gdf5 was investigated by examining the effect of gdf5 on the survival of dopaminergic neurons in glia-depleted midbrain cultures. |
2005-08-09 |
2023-08-12 |
rat |
| A Graulich, F Mercier, J Scuvée-Moreau, V Seutin, J-F Liégeoi. Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers. Bioorganic & medicinal chemistry. vol 13. issue 4. 2005-08-02. PMID:15670929. |
intracellular recordings on rat midbrain dopaminergic neurones were made in order to evaluate the putative blockade of sk channels by these molecules. |
2005-08-02 |
2023-08-12 |
rat |
| John E Lisman, Anthony A Grac. The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron. vol 46. issue 5. 2005-08-01. PMID:15924857. |
in this article we develop the concept that the hippocampus and the midbrain dopaminergic neurons of the ventral tegmental area (vta) form a functional loop. |
2005-08-01 |
2023-08-12 |
Not clear |
| F-Q Li, T Wang, Z Pei, B Liu, J-S Hon. Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 3. 2005-07-29. PMID:15503194. |
to test the potential neuroprotective effect of baicalein on dopaminergic neurons, primary midbrain neuron-glia cultures from e-14 rat embryos were used. |
2005-07-29 |
2023-08-12 |
rat |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) induces selective loss of dopaminergic neurons in the mammalian midbrain, eliciting symptoms characteristic of parkinson's disease. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
in contrast to mammals, the zebrafish does not possess a midbrain dopaminergic system. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
thus, dopaminergic neurons in the posterior tuberculum of the zebrafish may be homologous to the midbrain dopaminergic system of mammals. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Yael Niv, Michael O Duff, Peter Daya. Dopamine, uncertainty and TD learning. Behavioral and brain functions : BBF. vol 1. 2005-07-13. PMID:15953384. |
substantial evidence suggests that the phasic activities of dopaminergic neurons in the primate midbrain represent a temporal difference (td) error in predictions of future reward, with increases above and decreases below baseline consequent on positive and negative prediction errors, respectively. |
2005-07-13 |
2023-08-12 |
Not clear |
| Andreas Meyer-Lindenberg, Philip D Kohn, Bhaskar Kolachana, Shane Kippenhan, Aideen McInerney-Leo, Robert Nussbaum, Daniel R Weinberger, Karen Faith Berma. Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nature neuroscience. vol 8. issue 5. 2005-07-08. PMID:15821730. |
using multimodal neuroimaging in humans, we demonstrate specific interactions between prefrontal activity and midbrain dopaminergic synthesis. |
2005-07-08 |
2023-08-12 |
Not clear |
| Yuriko Iwakura, Ying-Shan Piao, Makoto Mizuno, Nobuyuki Takei, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Naw. Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857400. |
epidermal growth factor (egf) is a member of a structurally related family containing heparin-binding egf-like growth factor (hb-egf) and transforming growth factor alpha (tgfalpha) that exerts neurotrophic activity on midbrain dopaminergic neurons. |
2005-07-05 |
2023-08-12 |
human |
| Yuriko Iwakura, Ying-Shan Piao, Makoto Mizuno, Nobuyuki Takei, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Naw. Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857400. |
these findings suggest that the neurotrophic activity of egf is maintained by afferent signals of midbrain dopaminergic neurons and is impaired in patients with parkinson's disease. |
2005-07-05 |
2023-08-12 |
human |
| Pedro Barroso-Chinea, Ignacio Cruz-Muros, María S Aymerich, Manuel Rodríguez-Díaz, Domingo Afonso-Oramas, José L Lanciego, Tomás González-Hernánde. Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869477. |
striatal expression of gdnf and differential vulnerability of midbrain dopaminergic cells. |
2005-07-05 |
2023-08-12 |
rat |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. |
2005-07-05 |
2023-08-12 |
rat |
| Xiaoxi Zhuang, Justine Masson, Jay A Gingrich, Stephen Rayport, René He. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. Journal of neuroscience methods. vol 143. issue 1. 2005-06-30. PMID:15763133. |
in dat-cre mice, immunocytochemical staining of adult brains for the dopamine-synthetic enzyme tyrosine hydroxylase and for cre recombinase revealed that virtually all dopaminergic neurons in the ventral midbrain expressed cre. |
2005-06-30 |
2023-08-12 |
mouse |
| Hardy J Rideout, Isabelle C J Lang-Rollin, Magali Savalle, Leonidas Stefani. Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition. Journal of neurochemistry. vol 93. issue 5. 2005-06-24. PMID:15934949. |
dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate ihsp70, following proteasomal inhibition. |
2005-06-24 |
2023-08-12 |
rat |
| M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
our findings demonstrate that short-term ethanol administration may modulate dopaminergic transmission in the rat hypothalamus and striatum but this effect may be attenuated by down-regulation of op, in the midbrain after long-term alcohol consumption. |
2005-06-17 |
2023-08-12 |
rat |
| M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
our results suggest that reinforcing properties of ethanol may be partially mediated by mechanisms involving the ethanol-induced disturbing of dopaminergic metabolism in the midbrain and hypothalamus and serotoninergic metabolism in hypothalamus. |
2005-06-17 |
2023-08-12 |
rat |
| Julie K Anderse. Iron dysregulation and Parkinson's disease. Journal of Alzheimer's disease : JAD. vol 6. issue 6 Suppl. 2005-06-14. PMID:15665414. |
we hypothesize that increased oxidative stress associated with the disease may result in dysregulation of iron homeostasis in midbrain dopaminergic neurons via alterations in binding of iron regulatory proteins (irps). |
2005-06-14 |
2023-08-12 |
Not clear |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
in this study we measured thiol redox state (trs) and the oxidative stress indicator lipid peroxidation in midbrain and striatum of adult (4 months old) male control (+/+) and weaver (wv/wv) mice in order to relate them with oxidative stress in conditions of progressive and severe (approximately 70%) nigrostriatal dopaminergic neurodegeneration. |
2005-06-14 |
2023-08-12 |
mouse |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
our data show that the high degeneration of the dopaminergic nigrostriatal neurons in male adult wv/wv mice is accompanied by significant changes in trs and an increase in lipid peroxidation in the midbrain, suggesting involvement of oxidative stress in the degeneration of dopaminergic neurons. |
2005-06-14 |
2023-08-12 |
mouse |