| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laurent Roybon, Patrik Brundin, Jia-Yi L. Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes. Experimental neurology. vol 196. issue 2. 2006-01-25. PMID:16199035. |
to examine whether pa6 stromal cells can enhance the yield of dopaminergic differentiation from neural progenitors, we generated neurospheres from embryonic day 11.5 (e11.5) (midbrain and forebrain) and e14.5 (ventral mesencephalon and cortex) rat embryos and allowed them to differentiate in co-culture with pa6 cells or poly-l-lysine/laminin-coated dishes. |
2006-01-25 |
2023-08-12 |
mouse |
| Birgit Liss, Olga Haeckel, Johannes Wildmann, Takashi Miki, Susumu Seino, Jochen Roepe. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nature neuroscience. vol 8. issue 12. 2006-01-24. PMID:16299504. |
k-atp channels promote the differential degeneration of dopaminergic midbrain neurons. |
2006-01-24 |
2023-08-12 |
mouse |
| Birgit Liss, Olga Haeckel, Johannes Wildmann, Takashi Miki, Susumu Seino, Jochen Roepe. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nature neuroscience. vol 8. issue 12. 2006-01-24. PMID:16299504. |
the selective degeneration of dopaminergic (da) midbrain neurons in the substantia nigra (sn) is a hallmark of parkinson disease. |
2006-01-24 |
2023-08-12 |
mouse |
| Björn Steiniger-Brach, Beate D Kretschme. Different function of pedunculopontine GABA and glutamate receptors in nucleus accumbens dopamine, pedunculopontine glutamate and operant discriminative behavior. The European journal of neuroscience. vol 22. issue 7. 2006-01-23. PMID:16197512. |
however, the pedunculopontine tegmental nucleus (pptg) in the brainstem is connected with limbic structures as well as dopaminergic midbrain areas, which also project to the nucleus accumbens. |
2006-01-23 |
2023-08-12 |
rat |
| J Jankovic, S Chen, W D L. The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease. Progress in neurobiology. vol 77. issue 1-2. 2006-01-20. PMID:16243425. |
experimental studies in nurr1 knock-out mice indicate that nurr1 deficiency results in impaired dopaminergic function and increased vulnerability of those midbrain dopaminergic neurons that degenerate in pd. |
2006-01-20 |
2023-08-12 |
mouse |
| Tatiana M Korotkova, Alexei A Ponomarenko, Helmut L Haas, Olga A Sergeev. Differential expression of the homeobox gene Pitx3 in midbrain dopaminergic neurons. The European journal of neuroscience. vol 22. issue 6. 2006-01-10. PMID:16190884. |
differential expression of the homeobox gene pitx3 in midbrain dopaminergic neurons. |
2006-01-10 |
2023-08-12 |
rat |
| Tatiana M Korotkova, Alexei A Ponomarenko, Helmut L Haas, Olga A Sergeev. Differential expression of the homeobox gene Pitx3 in midbrain dopaminergic neurons. The European journal of neuroscience. vol 22. issue 6. 2006-01-10. PMID:16190884. |
the transcription factor pitx3 is expressed selectively in the midbrain and regulates the differentiation and survival of dopaminergic neurons. |
2006-01-10 |
2023-08-12 |
rat |
| Simone M Smits, Daniel S Mathon, J Peter H Burbach, Geert M J Ramakers, Marten P Smid. Molecular and cellular alterations in the Pitx3-deficient midbrain dopaminergic system. Molecular and cellular neurosciences. vol 30. issue 3. 2006-01-05. PMID:16140547. |
molecular and cellular alterations in the pitx3-deficient midbrain dopaminergic system. |
2006-01-05 |
2023-08-12 |
mouse |
| Simone M Smits, Daniel S Mathon, J Peter H Burbach, Geert M J Ramakers, Marten P Smid. Molecular and cellular alterations in the Pitx3-deficient midbrain dopaminergic system. Molecular and cellular neurosciences. vol 30. issue 3. 2006-01-05. PMID:16140547. |
parkinson's disease (pd) is a progressive neurodegenerative disorder characterized by loss of midbrain dopaminergic (mda) neurons in the substantia nigra compacta (snc). |
2006-01-05 |
2023-08-12 |
mouse |
| Hannah Taylor, Stephen L Minge. Regenerative medicine in Parkinson's disease: generation of mesencephalic dopaminergic cells from embryonic stem cells. Current opinion in biotechnology. vol 16. issue 5. 2005-12-16. PMID:16143504. |
parkinson's disease is a progressive neurodegenerative disorder caused by the loss of midbrain dopaminergic neurons. |
2005-12-16 |
2023-08-12 |
human |
| Vincent Seuti. Dopaminergic neurones: much more than dopamine? British journal of pharmacology. vol 146. issue 2. 2005-12-09. PMID:16025140. |
midbrain dopaminergic (da) neurones sustain important physiological functions such as control of motricity, signalling of the error in prediction of rewards and modulation of emotions and cognition. |
2005-12-09 |
2023-08-12 |
Not clear |
| Suzanne Numan, Christine M Gall, Kim B Seroog. Developmental expression of neurotrophins and their receptors in postnatal rat ventral midbrain. Journal of molecular neuroscience : MN. vol 27. issue 2. 2005-12-06. PMID:16186635. |
two members of the neurotrophin family, brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3), have been shown to increase the survival of dopaminergic neurons from the ventral midbrain in vitro. |
2005-12-06 |
2023-08-12 |
rat |
| Tsugunobu Andoh, P Boon Chock, Dennis L Murphy, Chuang C Chiue. Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl. Molecular pharmacology. vol 68. issue 5. 2005-11-28. PMID:16099847. |
we therefore investigated whether the redox protein trx plays any role in the neuroprotective mechanism of selegiline against mpp+-induced cytotoxicity in human sh-sy5y neuroblastoma cells and also in primary neuronal cultures of mouse midbrain dopaminergic neurons. |
2005-11-28 |
2023-08-12 |
mouse |
| Tsugunobu Andoh, P Boon Chock, Dennis L Murphy, Chuang C Chiue. Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl. Molecular pharmacology. vol 68. issue 5. 2005-11-28. PMID:16099847. |
selegiline-induced trx and associated neuroprotection were concomitantly blocked by the antisense against trx mrna, but not the sense or antisense mutant phosphothionate oligonucleotides, not only in human sh-sy5y cells but also in mouse primary neuronal culture of midbrain dopaminergic neurons. |
2005-11-28 |
2023-08-12 |
mouse |
| Emily Fitzpatrick, Keyoumars Ashkan, Bradley A Wallace, Alim-Louis Benabid, John Mitrofani. Differential survival patterns among midbrain dopaminergic cells of MPTP-treated monkeys and 6OHDA-lesioned rats. Anatomy and embryology. vol 210. issue 2. 2005-11-22. PMID:16151853. |
differential survival patterns among midbrain dopaminergic cells of mptp-treated monkeys and 6ohda-lesioned rats. |
2005-11-22 |
2023-08-12 |
rat |
| Emily Fitzpatrick, Keyoumars Ashkan, Bradley A Wallace, Alim-Louis Benabid, John Mitrofani. Differential survival patterns among midbrain dopaminergic cells of MPTP-treated monkeys and 6OHDA-lesioned rats. Anatomy and embryology. vol 210. issue 2. 2005-11-22. PMID:16151853. |
we explore the patterns of survival among dopaminergic cells of the midbrain in mptp-treated macaque monkeys and 6ohda-lesioned sprague-dawley rats. |
2005-11-22 |
2023-08-12 |
rat |
| Emily Fitzpatrick, Keyoumars Ashkan, Bradley A Wallace, Alim-Louis Benabid, John Mitrofani. Differential survival patterns among midbrain dopaminergic cells of MPTP-treated monkeys and 6OHDA-lesioned rats. Anatomy and embryology. vol 210. issue 2. 2005-11-22. PMID:16151853. |
brains were processed for tyrosine hydroxylase (th) and calbindin immunocytochemistry to label populations in the ventral and dorsal tiers of midbrain dopaminergic cells. |
2005-11-22 |
2023-08-12 |
rat |
| Rebekah J Jakel, Jonathan T Kern, Delinda A Johnson, Jeffrey A Johnso. Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. Toxicological sciences : an official journal of the Society of Toxicology. vol 87. issue 1. 2005-10-31. PMID:15976186. |
parkinson's disease, a progressive neurodegenerative disorder, is characterized by loss of midbrain dopaminergic neurons. |
2005-10-31 |
2023-08-12 |
mouse |
| Kathleen Deschamps, Réjean Coutur. The ventral tegmental area as a putative target for tachykinins in cardiovascular regulation. British journal of pharmacology. vol 145. issue 6. 2005-10-28. PMID:15895109. |
the present study provides the first pharmacological evidence that the three tachykinin receptors in the rat vta can affect the autonomic control of blood pressure and hr by increasing midbrain dopaminergic transmission. |
2005-10-28 |
2023-08-12 |
rat |
| Charleen T Chu, Jian-hui Zhu, Guodong Cao, Armando Signore, Suping Wang, Jun Che. Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells. Journal of neurochemistry. vol 94. issue 6. 2005-10-27. PMID:16156740. |
parkinson's disease is a debilitating neurodegenerative disease characterized by loss of midbrain dopaminergic neurons. |
2005-10-27 |
2023-08-12 |
mouse |