| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Charleen T Chu, Jian-hui Zhu, Guodong Cao, Armando Signore, Suping Wang, Jun Che. Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells. Journal of neurochemistry. vol 94. issue 6. 2005-10-27. PMID:16156740. |
studies of primary mouse midbrain cultures further supported a role for aif in caspase-independent cell death in mpp+-treated dopaminergic neurons. |
2005-10-27 |
2023-08-12 |
mouse |
| Dong-Youn Hwang, Sheila M Fleming, Paul Ardayfio, Taylor Moran-Gates, Hansoo Kim, Frank I Tarazi, Marie-Francoise Chesselet, Kwang-Soo Ki. 3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 8. 2005-10-26. PMID:15728853. |
although current genetic models of pd produce behavioral impairment and nigrostriatal dysfunction, they do not reproduce the loss of midbrain dopaminergic neurons and 3,4-dihydroxyphenylalanine (l-dopa) reversible behavioral deficits. |
2005-10-26 |
2023-08-12 |
mouse |
| Jan Lewerenz, Bartosz Zurowski, Lars Jenicke, Tobias Bäumer, Andrew J Lees, Alexander Müncha. Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 8. 2005-10-19. PMID:15838851. |
we suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension. |
2005-10-19 |
2023-08-12 |
Not clear |
| Chee Yeun Chung, Hyemyung Seo, Kai Christian Sonntag, Andrew Brooks, Ling Lin, Ole Isacso. Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection. Human molecular genetics. vol 14. issue 13. 2005-10-11. PMID:15888489. |
cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection. |
2005-10-11 |
2023-08-12 |
mouse |
| Y Sasa. Directed differentiation of neural and sensory tissues from embryonic stem cells in vitro. Ernst Schering Research Foundation workshop. issue 54. 2005-10-11. PMID:16080289. |
particularly, midbrain th+ dopaminergic neurons are generated efficiently in this system. |
2005-10-11 |
2023-08-12 |
mouse |
| Li Quan, Takaki Ishikawa, Tomomi Michiue, Dong-Ri Li, Dong Zhao, Shigeki Oritani, Bao-Li Zhu, Hitoshi Maed. Ubiquitin-immunoreactive structures in the midbrain of methamphetamine abusers. Legal medicine (Tokyo, Japan). vol 7. issue 3. 2005-09-29. PMID:15847821. |
these findings suggest dysfunction of the nigral dopaminergic neurons and pgm neurons in the midbrain in ma abuse, which may account for the clinical symptoms. |
2005-09-29 |
2023-08-12 |
human |
| Shankar J Chinta, Julie K Anderse. Dopaminergic neurons. The international journal of biochemistry & cell biology. vol 37. issue 5. 2005-09-09. PMID:15743669. |
dopaminergic neurons of the midbrain are the main source of dopamine (da) in the mammalian central nervous system. |
2005-09-09 |
2023-08-12 |
human |
| R H Andres, A W Huber, U Schlattner, A Pérez-Bouza, S H Krebs, R W Seiler, T Wallimann, H R Widme. Effects of creatine treatment on the survival of dopaminergic neurons in cultured fetal ventral mesencephalic tissue. Neuroscience. vol 133. issue 3. 2005-09-07. PMID:15890457. |
in the present study, we analyzed the effects of externally added creatine on the survival and morphology of dopaminergic neurons and also addressed its neuroprotective properties in primary cultures of e14 rat ventral mesencephalon. |
2005-09-07 |
2023-08-12 |
rat |
| Gerard W O'Keeffe, Peter Dockery, Aideen M Sulliva. Effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro. Journal of neurocytology. vol 33. issue 5. 2005-08-30. PMID:15906156. |
effects of growth/differentiation factor 5 on the survival and morphology of embryonic rat midbrain dopaminergic neurones in vitro. |
2005-08-30 |
2023-08-12 |
rat |
| Bret A Morrow, D Eugene Redmond, Robert H Roth, John D Elswort. Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey. The Journal of comparative neurology. vol 488. issue 2. 2005-08-30. PMID:15924344. |
these data have relevance to transplantation studies that employ fetal dopaminergic grafts, and to disorders hypothesized to result from damage to developing midbrain dopamine neurons. |
2005-08-30 |
2023-08-12 |
monkey |
| Monicque M Lorist, Maarten A S Boksem, K Richard Ridderinkho. Impaired cognitive control and reduced cingulate activity during mental fatigue. Brain research. Cognitive brain research. vol 24. issue 2. 2005-08-30. PMID:15993758. |
findings that (1) mental fatigue is associated with compromised performance monitoring and inadequate performance adjustments after errors, (2) monitoring functions of acc and striatum rely on dopaminergic inputs from the midbrain, and (3) patients with striatal dopamine deficiencies show symptomatic mental fatigue, suggest that mental fatigue results from a failure to maintain adequate levels of dopaminergic transmission to the striatum and the acc, resulting in impaired cognitive control. |
2005-08-30 |
2023-08-12 |
Not clear |
| Sarah L Maxwell, Hsin-Yi Ho, Eva Kuehner, Suling Zhao, Meng L. Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Developmental biology. vol 282. issue 2. 2005-08-22. PMID:15950611. |
therefore, our study provides the first direct evidence that the aphakia allele of pitx3 is a hypomorph and that pitx3 is required for the regulation of th expression in midbrain dopaminergic neurons as well as the generation and/or maintenance of these cells. |
2005-08-22 |
2023-08-12 |
mouse |
| Sarah L Maxwell, Hsin-Yi Ho, Eva Kuehner, Suling Zhao, Meng L. Pitx3 regulates tyrosine hydroxylase expression in the substantia nigra and identifies a subgroup of mesencephalic dopaminergic progenitor neurons during mouse development. Developmental biology. vol 282. issue 2. 2005-08-22. PMID:15950611. |
furthermore, using the targeted gfp reporter as a midbrain dopaminergic lineage marker, we have identified previously unrecognised ontogenetically distinct subpopulations of dopaminergic cells within the ventral midbrain based on their temporal and topographical expression of pitx3 and th. |
2005-08-22 |
2023-08-12 |
mouse |
| Tom N Grammatopoulos, Ferogh Ahmadi, Susan M Jones, Marc W Fariss, James A Weyhenmeyer, W Michael Zawad. Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. Brain research. vol 1045. issue 1-2. 2005-08-18. PMID:15910763. |
angiotensin ii protects cultured midbrain dopaminergic neurons against rotenone-induced cell death. |
2005-08-18 |
2023-08-12 |
rat |
| Siok L Dun, G Cristina Brailoiu, Keisuke Mizuo, Jun Yang, Jaw Kang Chang, Nae J Du. Neuropeptide B immunoreactivity in the central nervous system of the rat. Brain research. vol 1045. issue 1-2. 2005-08-18. PMID:15910774. |
tyrosine hydroxylase-positive neurons in the midbrain, presumably dopaminergic, were irnpb. |
2005-08-18 |
2023-08-12 |
mouse |
| Kai-Christian Sonntag, Rabi Simantov, Lars Björklund, Oliver Cooper, Jan Pruszak, Florian Kowalke, Jocelyn Gilmartin, Jixiang Ding, Ya-Ping Hu, Michael M Shen, Ole Isacso. Context-dependent neuronal differentiation and germ layer induction of Smad4-/- and Cripto-/- embryonic stem cells. Molecular and cellular neurosciences. vol 28. issue 3. 2005-08-09. PMID:15737733. |
es cell differentiation into catecholaminergic neurons showed that these es cells retained their ability to develop into dopaminergic and serotonergic neurons with typical expression patterns of midbrain and hindbrain genes. |
2005-08-09 |
2023-08-12 |
mouse |
| Ling Lin, Yi Rao, Ole Isacso. Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. Molecular and cellular neurosciences. vol 28. issue 3. 2005-08-09. PMID:15737744. |
netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. |
2005-08-09 |
2023-08-12 |
Not clear |
| Terri K Wood, Kieran W McDermott, Aideen M Sulliva. Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. Journal of neuroscience research. vol 80. issue 6. 2005-08-09. PMID:15880784. |
differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. |
2005-08-09 |
2023-08-12 |
rat |
| Terri K Wood, Kieran W McDermott, Aideen M Sulliva. Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. Journal of neuroscience research. vol 80. issue 6. 2005-08-09. PMID:15880784. |
parkinson's disease is characterized by the progressive degeneration of midbrain dopaminergic neurons. |
2005-08-09 |
2023-08-12 |
rat |
| Terri K Wood, Kieran W McDermott, Aideen M Sulliva. Differential effects of growth/differentiation factor 5 and glial cell line-derived neurotrophic factor on dopaminergic neurons and astroglia in cultures of embryonic rat midbrain. Journal of neuroscience research. vol 80. issue 6. 2005-08-09. PMID:15880784. |
here, the effects of gdf5 and gdnf on dopaminergic neuronal and astroglial survival and differentiation in embryonic rat midbrain cultures were examined. |
2005-08-09 |
2023-08-12 |
rat |