| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tania Vitalis, Olivier Cases, John G Parnavela. Development of the dopaminergic neurons in the rodent brainstem. Experimental neurology. vol 191 Suppl 1. 2005-03-29. PMID:15629757. |
the loss of dopaminergic (da) neurons in the ventral midbrain is the principal cause of parkinson's disease. |
2005-03-29 |
2023-08-12 |
Not clear |
| Bianca C Wittmann, Björn H Schott, Sebastian Guderian, Julietta U Frey, Hans-Jochen Heinze, Emrah Düze. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron. vol 45. issue 3. 2005-03-29. PMID:15694331. |
reward-related fmri activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. |
2005-03-29 |
2023-08-12 |
Not clear |
| Bianca C Wittmann, Björn H Schott, Sebastian Guderian, Julietta U Frey, Hans-Jochen Heinze, Emrah Düze. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron. vol 45. issue 3. 2005-03-29. PMID:15694331. |
long-term potentiation in the hippocampus can be enhanced and prolonged by dopaminergic inputs from midbrain structures such as the substantia nigra. |
2005-03-29 |
2023-08-12 |
Not clear |
| Bianca C Wittmann, Björn H Schott, Sebastian Guderian, Julietta U Frey, Hans-Jochen Heinze, Emrah Düze. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron. vol 45. issue 3. 2005-03-29. PMID:15694331. |
we used a condition that reliably elicits a dopaminergic response, reward anticipation, to study the relationship between activity of dopaminergic midbrain areas and hippocampal long-term memory in healthy adults. |
2005-03-29 |
2023-08-12 |
Not clear |
| Bianca C Wittmann, Björn H Schott, Sebastian Guderian, Julietta U Frey, Hans-Jochen Heinze, Emrah Düze. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron. vol 45. issue 3. 2005-03-29. PMID:15694331. |
these data are consistent with the hypothesis that activation of dopaminergic midbrain regions enhances hippocampus-dependent memory formation, possibly by enhancing consolidation. |
2005-03-29 |
2023-08-12 |
Not clear |
| Bin Liu, Jun Xia Xie, Dewi Kenneth Rowlands, Yu Lin Gou, Ching Cheong Leung, Yiu Wa Chung, Hsiao Chang Cha. Neuroprotective effects of Bak Foong Pill in 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine (MPTP)-induced Parkinson's disease model mice. Biological & pharmaceutical bulletin. vol 27. issue 8. 2005-03-18. PMID:15305030. |
mptp, a specific dopaminergic neurotoxin, significantly decreased dat and th mrna levels in the striatum, midbrain and cerebellum, but not the cortex, of c57bl/6 mice. |
2005-03-18 |
2023-08-12 |
mouse |
| Eleanor Dommett, Véronique Coizet, Charles D Blaha, John Martindale, Véronique Lefebvre, Natalie Walton, John E W Mayhew, Paul G Overton, Peter Redgrav. How visual stimuli activate dopaminergic neurons at short latency. Science (New York, N.Y.). vol 307. issue 5714. 2005-03-15. PMID:15746431. |
unexpected, biologically salient stimuli elicit a short-latency, phasic response in midbrain dopaminergic (da) neurons. |
2005-03-15 |
2023-08-12 |
rat |
| Bernard Le Foll, Jorge Diaz, Pierre Sokolof. Neuroadaptations to hyperdopaminergia in dopamine D3 receptor-deficient mice. Life sciences. vol 76. issue 11. 2005-03-07. PMID:15642598. |
the d3r is localized post-synaptically on nucleus accumbens neurons, but is also an autoreceptor on dopaminergic neurons in the mesencephalon. |
2005-03-07 |
2023-08-12 |
mouse |
| Marten P Smidt, Simone M Smits, J Peter H Burbac. Homeobox gene Pitx3 and its role in the development of dopamine neurons of the substantia nigra. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15300495. |
the homeobox gene pitx3 plays an important part in the development and function of vertebrate midbrain dopaminergic neurons. |
2005-03-04 |
2023-08-12 |
mouse |
| Eleni Roussa, Kerstin Krieglstei. Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15322912. |
induction and specification of midbrain dopaminergic cells: focus on shh, fgf8, and tgf-beta. |
2005-03-04 |
2023-08-12 |
mouse |
| Eleni Roussa, Kerstin Krieglstei. Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15322912. |
sonic hedgehog (shh), secreted by the notochord and floor plate, and fibroblast growth factor (fgf) 8, secreted by the isthmus, are thought to be key molecules involved in the development of midbrain dopaminergic neurons. |
2005-03-04 |
2023-08-12 |
mouse |
| Eleni Roussa, Kerstin Krieglstei. Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-beta. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15322912. |
during the last decade, the introduction of elegant explant culture systems and the generation of transgenic and mutant mice have greatly contributed to a better understanding of the molecular signals that direct the induction and specification of midbrain dopaminergic neurons. |
2005-03-04 |
2023-08-12 |
mouse |
| Nilima Prakash, Wolfgang Wurs. Specification of midbrain territory. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15322917. |
we will also give an outlook on genes that are active during early induction of the anterior neural plate and genetic mechanisms that control the generation of specific cell populations of the ventral midbrain, with special focus on the mesencephalic dopaminergic neurons. |
2005-03-04 |
2023-08-12 |
Not clear |
| Horst H Simon, Sandrine Thuret, Lavinia Alber. Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors. Cell and tissue research. vol 318. issue 1. 2005-03-04. PMID:15340832. |
midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors. |
2005-03-04 |
2023-08-12 |
mouse |
| Makoto Mizuno, Romulo S Malta, Tadasato Nagano, Hiroyuki Naw. Conditioned place preference and locomotor sensitization after repeated administration of cocaine or methamphetamine in rats treated with epidermal growth factor during the neonatal period. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542770. |
epidermal growth factor (egf) and its structurally related proteins are involved in the developmental regulation of various brain neurons, including midbrain dopaminergic neurons. |
2005-02-18 |
2023-08-12 |
rat |
| D Suwelack, A Hurtado-Lorenzo, E Millan, V Gonzalez-Nicolini, K Wawrowsky, P R Lowenstein, M G Castr. Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease. Gene therapy. vol 11. issue 24. 2005-02-16. PMID:15573088. |
experimentally, neurotoxins such as 6-hydroxydopamine (6-ohda) in rodents, and mptp in mice and non-human primates, are used to model the disease-induced degeneration of midbrain dopaminergic neurons. |
2005-02-16 |
2023-08-12 |
mouse |
| D Suwelack, A Hurtado-Lorenzo, E Millan, V Gonzalez-Nicolini, K Wawrowsky, P R Lowenstein, M G Castr. Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease. Gene therapy. vol 11. issue 24. 2005-02-16. PMID:15573088. |
however, recent reports have indicated the possibility that gdnf may, in the long term and if expressed in an unregulated manner, exert untoward effects on midbrain dopaminergic neuronal structure and function. |
2005-02-16 |
2023-08-12 |
mouse |
| D Suwelack, A Hurtado-Lorenzo, E Millan, V Gonzalez-Nicolini, K Wawrowsky, P R Lowenstein, M G Castr. Neuronal expression of the transcription factor Gli1 using the Talpha1 alpha-tubulin promoter is neuroprotective in an experimental model of Parkinson's disease. Gene therapy. vol 11. issue 24. 2005-02-16. PMID:15573088. |
these results suggest that expression of the transcription factor gli1 solely within neurons is neuroprotective for dopaminergic neurons in vivo and, furthermore, that neuronal-specific promoters are effective within the context of adenovirus-mediated gene therapy-induced neuroprotection of dopaminergic midbrain neurons. |
2005-02-16 |
2023-08-12 |
mouse |
| Yasushi Takagi, Jun Takahashi, Hidemoto Saiki, Asuka Morizane, Takuya Hayashi, Yo Kishi, Hitoshi Fukuda, Yo Okamoto, Masaomi Koyanagi, Makoto Ideguchi, Hideki Hayashi, Takayuki Imazato, Hiroshi Kawasaki, Hirofumi Suemori, Shigeki Omachi, Hidehiko Iida, Nobuyuki Itoh, Norio Nakatsuji, Yoshiki Sasai, Nobuo Hashimot. Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. The Journal of clinical investigation. vol 115. issue 1. 2005-02-10. PMID:15630449. |
parkinson disease (pd) is a neurodegenerative disorder characterized by loss of midbrain dopaminergic (da) neurons. |
2005-02-10 |
2023-08-12 |
monkey |
| Cha-Gyun Jung, Hideki Hida, Kensuke Nakahira, Kazuhiro Ikenaka, Hye-Jung Kim, Hitoo Nishin. Pleiotrophin mRNA is highly expressed in neural stem (progenitor) cells of mouse ventral mesencephalon and the product promotes production of dopaminergic neurons from embryonic stem cell-derived nestin-positive cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 11. 2005-02-08. PMID:15180956. |
pleiotrophin mrna is highly expressed in neural stem (progenitor) cells of mouse ventral mesencephalon and the product promotes production of dopaminergic neurons from embryonic stem cell-derived nestin-positive cells. |
2005-02-08 |
2023-08-12 |
mouse |