| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) induces selective loss of dopaminergic neurons in the mammalian midbrain, eliciting symptoms characteristic of parkinson's disease. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
in contrast to mammals, the zebrafish does not possess a midbrain dopaminergic system. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Chen Sok Lam, Vladimir Korzh, Uwe Strahl. Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP. The European journal of neuroscience. vol 21. issue 6. 2005-07-26. PMID:15845104. |
thus, dopaminergic neurons in the posterior tuberculum of the zebrafish may be homologous to the midbrain dopaminergic system of mammals. |
2005-07-26 |
2023-08-12 |
zebrafish |
| Yael Niv, Michael O Duff, Peter Daya. Dopamine, uncertainty and TD learning. Behavioral and brain functions : BBF. vol 1. 2005-07-13. PMID:15953384. |
substantial evidence suggests that the phasic activities of dopaminergic neurons in the primate midbrain represent a temporal difference (td) error in predictions of future reward, with increases above and decreases below baseline consequent on positive and negative prediction errors, respectively. |
2005-07-13 |
2023-08-12 |
Not clear |
| Andreas Meyer-Lindenberg, Philip D Kohn, Bhaskar Kolachana, Shane Kippenhan, Aideen McInerney-Leo, Robert Nussbaum, Daniel R Weinberger, Karen Faith Berma. Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nature neuroscience. vol 8. issue 5. 2005-07-08. PMID:15821730. |
using multimodal neuroimaging in humans, we demonstrate specific interactions between prefrontal activity and midbrain dopaminergic synthesis. |
2005-07-08 |
2023-08-12 |
Not clear |
| Yuriko Iwakura, Ying-Shan Piao, Makoto Mizuno, Nobuyuki Takei, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Naw. Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857400. |
epidermal growth factor (egf) is a member of a structurally related family containing heparin-binding egf-like growth factor (hb-egf) and transforming growth factor alpha (tgfalpha) that exerts neurotrophic activity on midbrain dopaminergic neurons. |
2005-07-05 |
2023-08-12 |
human |
| Yuriko Iwakura, Ying-Shan Piao, Makoto Mizuno, Nobuyuki Takei, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Naw. Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. Journal of neurochemistry. vol 93. issue 4. 2005-07-05. PMID:15857400. |
these findings suggest that the neurotrophic activity of egf is maintained by afferent signals of midbrain dopaminergic neurons and is impaired in patients with parkinson's disease. |
2005-07-05 |
2023-08-12 |
human |
| Pedro Barroso-Chinea, Ignacio Cruz-Muros, María S Aymerich, Manuel Rodríguez-Díaz, Domingo Afonso-Oramas, José L Lanciego, Tomás González-Hernánde. Striatal expression of GDNF and differential vulnerability of midbrain dopaminergic cells. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869477. |
striatal expression of gdnf and differential vulnerability of midbrain dopaminergic cells. |
2005-07-05 |
2023-08-12 |
rat |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. |
2005-07-05 |
2023-08-12 |
rat |
| Xiaoxi Zhuang, Justine Masson, Jay A Gingrich, Stephen Rayport, René He. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. Journal of neuroscience methods. vol 143. issue 1. 2005-06-30. PMID:15763133. |
in dat-cre mice, immunocytochemical staining of adult brains for the dopamine-synthetic enzyme tyrosine hydroxylase and for cre recombinase revealed that virtually all dopaminergic neurons in the ventral midbrain expressed cre. |
2005-06-30 |
2023-08-12 |
mouse |
| Hardy J Rideout, Isabelle C J Lang-Rollin, Magali Savalle, Leonidas Stefani. Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition. Journal of neurochemistry. vol 93. issue 5. 2005-06-24. PMID:15934949. |
dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate ihsp70, following proteasomal inhibition. |
2005-06-24 |
2023-08-12 |
rat |
| M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
our findings demonstrate that short-term ethanol administration may modulate dopaminergic transmission in the rat hypothalamus and striatum but this effect may be attenuated by down-regulation of op, in the midbrain after long-term alcohol consumption. |
2005-06-17 |
2023-08-12 |
rat |
| M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
our results suggest that reinforcing properties of ethanol may be partially mediated by mechanisms involving the ethanol-induced disturbing of dopaminergic metabolism in the midbrain and hypothalamus and serotoninergic metabolism in hypothalamus. |
2005-06-17 |
2023-08-12 |
rat |
| Julie K Anderse. Iron dysregulation and Parkinson's disease. Journal of Alzheimer's disease : JAD. vol 6. issue 6 Suppl. 2005-06-14. PMID:15665414. |
we hypothesize that increased oxidative stress associated with the disease may result in dysregulation of iron homeostasis in midbrain dopaminergic neurons via alterations in binding of iron regulatory proteins (irps). |
2005-06-14 |
2023-08-12 |
Not clear |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
in this study we measured thiol redox state (trs) and the oxidative stress indicator lipid peroxidation in midbrain and striatum of adult (4 months old) male control (+/+) and weaver (wv/wv) mice in order to relate them with oxidative stress in conditions of progressive and severe (approximately 70%) nigrostriatal dopaminergic neurodegeneration. |
2005-06-14 |
2023-08-12 |
mouse |
| Nikolaos Patsoukis, Ioannis Papapostolou, George Zervoudakis, Christos D Georgiou, Nikolaos A Matsokis, Nikolaos T Panagopoulo. Thiol redox state and oxidative stress in midbrain and striatum of weaver mutant mice, a genetic model of nigrostriatal dopamine deficiency. Neuroscience letters. vol 376. issue 1. 2005-06-14. PMID:15694268. |
our data show that the high degeneration of the dopaminergic nigrostriatal neurons in male adult wv/wv mice is accompanied by significant changes in trs and an increase in lipid peroxidation in the midbrain, suggesting involvement of oxidative stress in the degeneration of dopaminergic neurons. |
2005-06-14 |
2023-08-12 |
mouse |
| Juliann D Jaumotte, Michael J Zigmon. Dopaminergic innervation of forebrain by ventral mesencephalon in organotypic slice co-cultures: effects of GDNF. Brain research. Molecular brain research. vol 134. issue 1. 2005-06-13. PMID:15790537. |
dopaminergic innervation of forebrain by ventral mesencephalon in organotypic slice co-cultures: effects of gdnf. |
2005-06-13 |
2023-08-12 |
rat |
| Giia-Sheun Peng, Guorong Li, Nian-Sheng Tzeng, Po-See Chen, De-Maw Chuang, Yaw-Don Hsu, Sufen Yang, Jau-Shyong Hon. Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia. Brain research. Molecular brain research. vol 134. issue 1. 2005-06-13. PMID:15790540. |
valproate pretreatment protects dopaminergic neurons from lps-induced neurotoxicity in rat primary midbrain cultures: role of microglia. |
2005-06-13 |
2023-08-12 |
rat |
| Masami Ishido, Masatoshi Morita, Syuichi Oka, Yoshinori Masu. Alteration of gene expression of G protein-coupled receptors in endocrine disruptors-caused hyperactive rats. Regulatory peptides. vol 126. issue 1-2. 2005-06-10. PMID:15620428. |
based on dna macroarray analyses of the midbrain at 8 weeks of age, the endocrine disruptors altered the levels of gene expression of g protein-coupled receptors that were involved in not only dopaminergic neurotransduction but also many peptidergic neurotransduction. |
2005-06-10 |
2023-08-12 |
rat |
| Allison N McCoy, Michael L Plat. Expectations and outcomes: decision-making in the primate brain. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 191. issue 3. 2005-05-27. PMID:15759141. |
other brain areas have been implicated in the processing of reward-related information in the abstract: midbrain dopaminergic neurons, for instance, signal an error in reward prediction. |
2005-05-27 |
2023-08-12 |
Not clear |