| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Codina, Gerard Benoit, John T Gooch, David Neuhaus, Thomas Perlmann, John W R Schwab. Identification of a novel co-regulator interaction surface on the ligand binding domain of Nurr1 using NMR footprinting. The Journal of biological chemistry. vol 279. issue 51. 2005-02-04. PMID:15456745. |
the nuclear receptor nurr1 is a transcription factor essential for the development of midbrain dopaminergic neurons in vertebrates. |
2005-02-04 |
2023-08-12 |
drosophila_melanogaster |
| Gi-Ryang Kweon, Jeremy D Marks, Robert Krencik, Eric H Leung, Paul T Schumacker, Keith Hyland, Un Jung Kan. Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells. The Journal of biological chemistry. vol 279. issue 50. 2005-02-01. PMID:15469939. |
to elucidate the mechanisms of chronic complex i disruption-induced neurodegeneration, we induced differentiation of immortalized midbrain dopaminergic (mn9d) and non-dopaminergic (mn9x) neuronal cells, to maintain them in culture without significant cell proliferation and compared their survivals following chronic exposure to nanomolar rotenone, an irreversible complex i inhibitor. |
2005-02-01 |
2023-08-12 |
Not clear |
| Cecilia Huerta, Victoria Alvarez, Ignacio F Mata, Eliecer Coto, René Ribacoba, Carmen Martínez, Marta Blázquez, Luis M Guisasola, Carlos Salvador, Carlos H Lahoz, Joaquín Peñ. Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease. Neuroscience letters. vol 370. issue 2-3. 2005-01-31. PMID:15488313. |
parkinson's disease (pd) is a complex disorder characterized by the progressive degeneration of dopaminergic neurons in the midbrain. |
2005-01-31 |
2023-08-12 |
Not clear |
| Manabu Inoue, Yukinori Katsumi, Takuya Hayashi, Takahiro Mukai, Koichi Ishizu, Kazuo Hashikawa, Hideo Saji, Hidenao Fukuyam. Sensory stimulation accelerates dopamine release in the basal ganglia. Brain research. vol 1026. issue 2. 2005-01-31. PMID:15488479. |
accordingly, we suggest that the activity of the dopaminergic neurons in the midbrain projecting to the nucleus accumbens and the striatum is modulated by the input from the afferent nerves. |
2005-01-31 |
2023-08-12 |
Not clear |
| K Stiasny-Kolster, Y Doerr, J C Möller, H Höffken, T M Behr, W H Oertel, G Maye. Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT. Brain : a journal of neurology. vol 128. issue Pt 1. 2005-01-28. PMID:15548552. |
midbrain lesions are found only in stage 3, in particular degeneration of dopaminergic neurons in the substantia nigra pars compacta. |
2005-01-28 |
2023-08-12 |
human |
| Sandrine Thuret, Kambiz N Alavian, Martin Gassmann, C Kent Lloyd, Simone M Smits, Marten P Smidt, Rüdiger Klein, Richard H Dyck, Horst H Simo. The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. Journal of neurochemistry. vol 91. issue 6. 2005-01-21. PMID:15584907. |
the distribution of dopaminergic cell bodies in the midbrain, the expression of numerous genes specific to mesencephalic dopaminergic neurons, and the axonal projection to the basal ganglia all appeared normal. |
2005-01-21 |
2023-08-12 |
mouse |
| Lixin Zhang, Anita Fletcher-Turner, Mark A Marchionni, Subbu Apparsundaram, Kerstin H Lundgren, David M Yurek, Kim B Seroog. Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. Journal of neurochemistry. vol 91. issue 6. 2005-01-21. PMID:15584912. |
neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. |
2005-01-21 |
2023-08-12 |
rat |
| Lixin Zhang, Anita Fletcher-Turner, Mark A Marchionni, Subbu Apparsundaram, Kerstin H Lundgren, David M Yurek, Kim B Seroog. Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. Journal of neurochemistry. vol 91. issue 6. 2005-01-21. PMID:15584912. |
because midbrain dopamine (da) cells express the nrg receptor, erbb4, the present study examined the potential neurotrophic and/or neuroprotective effects of ggf2 on cultured primary dopaminergic neurons. |
2005-01-21 |
2023-08-12 |
rat |
| G Garcia, P Tagliaferro, A Ferri, A M Evangelista de Duffard, R Duffard, A Brusc. Study of tyrosine hydroxylase immunoreactive neurons in neonate rats lactationally exposed to 2,4-dichlorophenoxyacetic Acid. Neurotoxicology. vol 25. issue 6. 2005-01-14. PMID:15474613. |
dopaminergic neurons from the midbrain nuclei substantia nigra (sn; a9) and ventral tegmental area (vta; a10) were investigated by tyrosine hydroxylase (th) immunostaining in neonate rat brains exposed to 2,4-dichlorophenoxyacetic acid (2,4-d) through lactation. |
2005-01-14 |
2023-08-12 |
rat |
| Ezia Guatteo, C Peter Bengtson, Giorgio Bernardi, Nicola B Mercur. Voltage-gated calcium channels mediate intracellular calcium increase in weaver dopaminergic neurons during stimulation of D2 and GABAB receptors. Journal of neurophysiology. vol 92. issue 6. 2004-12-30. PMID:15240766. |
the weaver (wv) mutation affects the pore-forming region of the inwardly rectifying potassium channel (girk) leading to degeneration of cerebellar granule and midbrain dopaminergic neurons. |
2004-12-30 |
2023-08-12 |
mouse |
| Ezia Guatteo, C Peter Bengtson, Giorgio Bernardi, Nicola B Mercur. Voltage-gated calcium channels mediate intracellular calcium increase in weaver dopaminergic neurons during stimulation of D2 and GABAB receptors. Journal of neurophysiology. vol 92. issue 6. 2004-12-30. PMID:15240766. |
here we performed whole cell patch-clamp recordings combined with microfluorometry to investigate possible differences in calcium ([ca2+]i) dynamics in native dopaminergic neurons (expressing the wvgirk2 subunits) in the midbrain slice preparation from homozygous weaver (wv/wv) and control (+/+) mice. |
2004-12-30 |
2023-08-12 |
mouse |
| Samina S Riaz, Spyridon Theofilopoulos, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The differentiation potential of human foetal neuronal progenitor cells in vitro. Brain research. Developmental brain research. vol 153. issue 1. 2004-12-21. PMID:15464216. |
previously, this laboratory has shown that human foetal progenitor cells derived from ventral mesencephalon (vm) can be developmentally directed towards a dopaminergic lineage. |
2004-12-21 |
2023-08-12 |
human |
| Bénédicte Salthun-Lassalle, Etienne C Hirsch, Jakob Wolfart, Merle Ruberg, Patrick P Miche. Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 26. 2004-12-16. PMID:15229240. |
we used a model system in which dopaminergic (da) neurons from embryonic rat mesencephalon undergo spontaneous and selective degeneration as they develop in culture. |
2004-12-16 |
2023-08-12 |
rat |
| Elise Nsegbe, Asa Wallén-Mackenzie, Stephane Dauger, Jean-Christophe Roux, Yuri Shvarev, Hugo Lagercrantz, Thomas Perlmann, Eric Herleniu. Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice. The Journal of physiology. vol 556. issue Pt 1. 2004-11-09. PMID:14742729. |
gene-targeted mice lacking nurr1 fail to develop midbrain dopaminergic neurones and do not survive beyond 24 h after birth. |
2004-11-09 |
2023-08-12 |
mouse |
| Mark Zervas, Sandrine Millet, Sohyun Ahn, Alexandra L Joyne. Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron. vol 43. issue 3. 2004-11-02. PMID:15294143. |
finally, we also uncovered transient and differential genetic lineages of ventral midbrain dopaminergic and ventral hindbrain serotonergic neuronal precursors with respect to wnt1 and gli1 expression. |
2004-11-02 |
2023-08-12 |
mouse |
| Anselme L Perrier, Viviane Tabar, Tiziano Barberi, Maria E Rubio, Juan Bruses, Norbert Topf, Neil L Harrison, Lorenz Stude. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 34. 2004-10-18. PMID:15310843. |
here, we describe conditions to direct hes cells into neurons of midbrain dopaminergic identity. |
2004-10-18 |
2023-08-12 |
human |
| Zhaoliang Hu, Margaret Cooper, David P Crockett, Renping Zho. Differentiation of the midbrain dopaminergic pathways during mouse development. The Journal of comparative neurology. vol 476. issue 3. 2004-10-07. PMID:15269972. |
differentiation of the midbrain dopaminergic pathways during mouse development. |
2004-10-07 |
2023-08-12 |
mouse |
| Zhaoliang Hu, Margaret Cooper, David P Crockett, Renping Zho. Differentiation of the midbrain dopaminergic pathways during mouse development. The Journal of comparative neurology. vol 476. issue 3. 2004-10-07. PMID:15269972. |
dopaminergic (da) neurons in the substantia nigra (sn) and ventral tegmental area (vta) of the midbrain project to the dorsolateral caudate/putamen and to the ventromedially located nucleus accumbens, respectively, establishing the mesostriatal and the mesolimbic pathways. |
2004-10-07 |
2023-08-12 |
mouse |
| Sarah A Baker, K Adam Baker, Theo Hag. Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone. The European journal of neuroscience. vol 20. issue 2. 2004-09-30. PMID:15233767. |
the location of dopaminergic projections from the midbrain to the neostriatum and nucleus accumbens overlaps with the most active region of neurogenesis in the adult brain, the subventricular zone of the anterior lateral ventricle. |
2004-09-30 |
2023-08-12 |
mouse |
| Min-Yau Teo, Michiel van Wyk, John Lin, Janusz Lipsk. Differential effects of nicotine on the activity of substantia nigra and ventral tegmental area dopaminergic neurons in vitro. Acta neurobiologiae experimentalis. vol 64. issue 2. 2004-09-30. PMID:15366245. |
low concentrations of nicotine can thus profoundly modulate the activity of dopaminergic mesencephalic neurons through a local action within the ventral midbrain in vitro, and, similarly to in vivo conditions, evoke stronger effects in the vta. |
2004-09-30 |
2023-08-12 |
rat |