| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin-Xia Dai, Ze-Lan Hu, Ming Shi, Chao Guo, Yu-Qiang Din. Postnatal ontogeny of the transcription factor Lmx1b in the mouse central nervous system. The Journal of comparative neurology. vol 509. issue 4. 2008-09-02. PMID:18512225. |
lmx1b was observed in dopaminergic neurons in the midbrain and serotonergic neurons in the hindbrain, as determined by double labeling with specific markers. |
2008-09-02 |
2023-08-12 |
mouse |
| Li-ying Yu, Mart Saarma, Urmas Arumä. Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 30. 2008-09-02. PMID:18650325. |
neurotrophic factors, including glial cell line-derived neurotrophic factor (gdnf) and brain-derived neurotrophic factor (bdnf), promote survival of midbrain dopaminergic neurons, but the death pathways activated in the dopaminergic neurons by deprivation of these factors are poorly studied. |
2008-09-02 |
2023-08-12 |
Not clear |
| D Moses, J Drago, Y Teper, I Gantois, D I Finkelstein, M K Horn. Fetal striatum- and ventral mesencephalon-derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo. Neuroscience. vol 154. issue 2. 2008-08-29. PMID:18472226. |
in this study we show that fetal e11 striatum-derived neurospheres and e14.5 ventral mesencephalon (vm) -derived neurospheres (ns e11 and nsvm, respectively) are a source of factors that rescue dopaminergic neurons. |
2008-08-29 |
2023-08-12 |
mouse |
| Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y Abramov, Andrey S Y Abramov, Erik A Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R Duchen, David Latchman, Sarah J Tabrizi, Nicholas W Woo. PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PloS one. vol 3. issue 6. 2008-08-20. PMID:18560593. |
using rnai, we created stable pink1 knockdown in human dopaminergic neurons differentiated from foetal ventral mesencephalon stem cells, as well as in an immortalised human neuroblastoma cell line. |
2008-08-20 |
2023-08-12 |
mouse |
| C Xiao, J-H Y. Ethanol dually modulates GABAergic synaptic transmission onto dopaminergic neurons in ventral tegmental area: role of mu-opioid receptors. Neuroscience. vol 153. issue 1. 2008-08-18. PMID:18343590. |
ipscs were mediated by gaba(a) receptors and were recorded from vta dopaminergic neurons in acute midbrain slices of rats. |
2008-08-18 |
2023-08-12 |
rat |
| R G Nair-Roberts, S D Chatelain-Badie, E Benson, H White-Cooper, J P Bolam, M A Ungles. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18355970. |
these results demonstrate that gabaergic and glutamatergic neurons represent large proportions of the neurons in what are traditionally considered as dopamine nuclei and that there are considerable heterogeneities in the proportions of cell types in the different dopaminergic midbrain regions. |
2008-08-07 |
2023-08-12 |
rat |
| Eva Hedlund, Jan Pruszak, Thomas Lardaro, Wesley Ludwig, Angel Viñuela, Kwang-Soo Kim, Ole Isacso. Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease. Stem cells (Dayton, Ohio). vol 26. issue 6. 2008-08-06. PMID:18388307. |
transplantation to 6-hydroxydopamine-lesioned rats showed that an enriched dopaminergic population could survive and restore both amphetamine- and apomorphine-induced functions, and the grafts contained large numbers of midbrain dopamine neurons, which innervated the host striatum. |
2008-08-06 |
2023-08-12 |
mouse |
| Samuel D Gale, Abigail L Person, David J Perke. A novel basal ganglia pathway forms a loop linking a vocal learning circuit with its dopaminergic input. The Journal of comparative neurology. vol 508. issue 5. 2008-08-01. PMID:18398824. |
instead, we describe an indirect pathway from area x to midbrain dopaminergic neurons via a connection in the ventral pallidum (vp). |
2008-08-01 |
2023-08-12 |
Not clear |
| Ikuko Mizuta, Tatsuhiko Tsunoda, Wataru Satake, Yuko Nakabayashi, Masahiko Watanabe, Atsushi Takeda, Kazuko Hasegawa, Kenji Nakashima, Mitsutoshi Yamamoto, Nobutaka Hattori, Miho Murata, Tatsushi Tod. Calbindin 1, fibroblast growth factor 20, and alpha-synuclein in sporadic Parkinson's disease. Human genetics. vol 124. issue 1. 2008-07-30. PMID:18568448. |
parkinson's disease (pd), one of the most common human neurodegenerative disorders, is characterized by the loss of dopaminergic neurons in the substantia nigra of the midbrain. |
2008-07-30 |
2023-08-12 |
human |
| Jianyong Wang, Helen M Duhart, Zengjun Xu, Tucker A Patterson, Glenn D Newport, Syed F Al. Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18069091. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons with unknown etiology. |
2008-07-28 |
2023-08-12 |
Not clear |
| Dianne M A Van den Heuvel, R Jeroen Pasterkam. Getting connected in the dopamine system. Progress in neurobiology. vol 85. issue 1. 2008-07-23. PMID:18304718. |
dopaminergic neurons located in the ventral midbrain (i.e. |
2008-07-23 |
2023-08-12 |
Not clear |
| Linda C Edman, Helena Mira, Ernest Arena. The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. Experimental cell research. vol 314. issue 10. 2008-07-23. PMID:18420193. |
the beta-chemokines ccl2 and ccl7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons. |
2008-07-23 |
2023-08-12 |
mouse |
| Michele Migliore, Claudio Cannia, Carmen C Canavie. A modeling study suggesting a possible pharmacological target to mitigate the effects of ethanol on reward-related dopaminergic signaling. Journal of neurophysiology. vol 99. issue 5. 2008-07-22. PMID:18353916. |
midbrain dopaminergic neurons are involved in several critical brain functions controlling goal-directed behaviors, reinforcing/reward processes, and motivation. |
2008-07-22 |
2023-08-12 |
Not clear |
| Sonia Bonilla, Anita C Hall, Luisa Pinto, Alessio Attardo, Magdalena Götz, Wieland B Huttner, Ernest Arena. Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia. vol 56. issue 8. 2008-07-10. PMID:18351630. |
identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. |
2008-07-10 |
2023-08-12 |
mouse |
| Sonia Bonilla, Anita C Hall, Luisa Pinto, Alessio Attardo, Magdalena Götz, Wieland B Huttner, Ernest Arena. Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors. Glia. vol 56. issue 8. 2008-07-10. PMID:18351630. |
however, in the midbrain, the fp contains neurons of the dopaminergic (da) lineage that require contact with radial glia-like cells for their induction. |
2008-07-10 |
2023-08-12 |
mouse |
| R Willemssen, T Müller, M Schwarz, J Hohnsbein, M Falkenstei. Error processing in patients with Parkinson's disease: the influence of medication state. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18250959. |
error processing, as reflected in a component of the event-related potential, the so-called error (related) negativity (ne or ern) is likely dependent on the midbrain dopaminergic system. |
2008-07-01 |
2023-08-12 |
human |
| Roy V Sillitoe, Michael W Voge. Desire, disease, and the origins of the dopaminergic system. Schizophrenia bulletin. vol 34. issue 2. 2008-06-27. PMID:18283047. |
the dopaminergic neurons in the midbrain region of the central nervous system project an extensive network of connections throughout the forebrain, including the neocortex. |
2008-06-27 |
2023-08-12 |
Not clear |
| Roy V Sillitoe, Michael W Voge. Desire, disease, and the origins of the dopaminergic system. Schizophrenia bulletin. vol 34. issue 2. 2008-06-27. PMID:18283047. |
based on the importance of the midbrain dopaminergic neurons to normal and pathological brain function, there is considerable interest in the molecular mechanisms that regulate their development. |
2008-06-27 |
2023-08-12 |
Not clear |
| Roy V Sillitoe, Michael W Voge. Desire, disease, and the origins of the dopaminergic system. Schizophrenia bulletin. vol 34. issue 2. 2008-06-27. PMID:18283047. |
midbrain dopaminergic neurons are descended from progenitor cells located near the ventral midline of the neural tube floor plate around the cephalic flexure. |
2008-06-27 |
2023-08-12 |
Not clear |
| Trine R Larsen, Ann-Sofi Söderling, Kenneth Caidahl, Peter Roepstorff, Jan Bert Gramsberge. Nitration of soluble proteins in organotypic culture models of Parkinson's disease. Neurochemistry international. vol 52. issue 3. 2008-06-20. PMID:17900761. |
here we quantified protein-bound 3-nitrotyrosine (3-nt) by a novel gas chromatography/negative chemical ionization tandem mass spectrometry technique and da and 3,4-dihydroxyphenylalanine (dopa) by hplc in tissues or medium of organotypic, mouse mesencephalon cultures after acute or chronic treatments with the peroxynitrite donor 3-morpholino-sydnonimine (sin-1), the dopaminergic toxin 1-methyl-4-phenylpyridinium (mpp(+)) or the lipophilic complex i inhibitor rotenone. |
2008-06-20 |
2023-08-12 |
mouse |