| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Princy S Quadros, Lisa J Schlueter, Christine K Wagne. Distribution of progesterone receptor immunoreactivity in the midbrain and hindbrain of postnatal rats. Developmental neurobiology. vol 68. issue 12. 2008-11-26. PMID:18712784. |
the results demonstrate that pr is transiently expressed within the first 2 weeks of life in specific motor, sensory and reticular core nuclei as well as within midbrain dopaminergic cell groups such as the substantia nigra and the ventral tegmental area. |
2008-11-26 |
2023-08-12 |
mouse |
| Dharshan Kumaran, Emrah Duze. The hippocampus and dopaminergic midbrain: old couple, new insights. Neuron. vol 60. issue 2. 2008-11-26. PMID:18957213. |
the hippocampus and dopaminergic midbrain: old couple, new insights. |
2008-11-26 |
2023-08-12 |
Not clear |
| Dharshan Kumaran, Emrah Duze. The hippocampus and dopaminergic midbrain: old couple, new insights. Neuron. vol 60. issue 2. 2008-11-26. PMID:18957213. |
in this issue of neuron, shohamy and wagner reveal how generalizations naturally emerge during associative learning through a partnership between putatively dopaminergic circuitry in the midbrain and the hippocampus. |
2008-11-26 |
2023-08-12 |
Not clear |
| Eleni Roussa, Oliver Oehlke, Belal Rahhal, Stephan Heermann, Stefanie Heidrich, Michael Wiehle, Kerstin Krieglstei. Transforming growth factor beta cooperates with persephin for dopaminergic phenotype induction. Stem cells (Dayton, Ohio). vol 26. issue 7. 2008-11-18. PMID:18420832. |
the aim of the present study was to investigate the putative cooperative effects of transforming growth factor beta (tgf-beta) and glial cell line-derived neurotrophic factor (gdnf) family ligands in the differentiation of midbrain progenitors toward a dopaminergic phenotype. |
2008-11-18 |
2023-08-12 |
mouse |
| Linda C Edman, Helena Mira, Alejandro Erices, Seth Malmersjö, Emma Andersson, Per Uhlén, Ernest Arena. Alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres. Stem cells (Dayton, Ohio). vol 26. issue 7. 2008-11-18. PMID:18436867. |
alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres. |
2008-11-18 |
2023-08-12 |
rat |
| Melissa K McCoy, Kelly A Ruhn, Terina N Martinez, Fiona E McAlpine, Armin Blesch, Malú G Tanse. Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats. Molecular therapy : the journal of the American Society of Gene Therapy. vol 16. issue 9. 2008-11-18. PMID:18628756. |
neuroinflammatory processes have been implicated in the progressive loss of ventral midbrain dopaminergic (da) neurons that give rise to parkinson's disease (pd), a late-onset movement disorder that affects 2% of the population over the age of 70 years. |
2008-11-18 |
2023-08-12 |
rat |
| Massimiliano Di Filippo, Barbara Picconi, Alessandro Tozzi, Veronica Ghiglieri, Aroldo Rossi, Paolo Calabres. The endocannabinoid system in Parkinson's disease. Current pharmaceutical design. vol 14. issue 23. 2008-11-17. PMID:18781984. |
parkinson's disease (pd) is a chronic and progressive neurodegenerative disorder of largely unknown etiology caused by a pathological cascade resulting in the degeneration of midbrain dopaminergic neurons of the substantia nigra pars compacta (snpc) projecting to the nucleus striatum, the main input station of the basal ganglia neuronal circuit. |
2008-11-17 |
2023-08-12 |
Not clear |
| Paolo Calabresi, Massimiliano Di Filipp. ACh/dopamine crosstalk in motor control and reward: a crucial role for alpha 6-containing nicotinic receptors? Neuron. vol 60. issue 1. 2008-11-06. PMID:18940582. |
the midbrain dopaminergic system is a key element in the control of motor activity, cognition, and the motivational effects of drugs of abuse, including nicotine. |
2008-11-06 |
2023-08-12 |
Not clear |
| Emilce Carrasco, Peter Werner, Diana Caspe. Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress. Neuroscience letters. vol 441. issue 1. 2008-11-05. PMID:18597941. |
here we investigated if and how ep2 activation might alter the survival of dopaminergic neurons following selective low-level oxidative injury evoked by the neurotoxin 6-hydroxydopamine (6-ohda) in primary neuronal cultures prepared from embryonic rat midbrain. |
2008-11-05 |
2023-08-12 |
human |
| Prem Prakash Tripathi, Luca Giovanni Di Giovannantonio, Alessandro Viegi, Wolfgang Wurst, Antonio Simeone, Yuri Bozz. Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 37. 2008-11-03. PMID:18784307. |
mutant mice, in which otx2 was conditionally inactivated by a cre recombinase expressed under the transcriptional control of the engrailed1 (en1) gene (en1(cre/+); otx2(flox/flox)), show a reduced number of dopaminergic neurons and an increased number of serotonergic neurons in the ventral midbrain. |
2008-11-03 |
2023-08-12 |
mouse |
| Yu Luo, Feng Xing, Rita Guiliano, Howard J Federof. Identification of a novel nurr1-interacting protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 37. 2008-11-03. PMID:18784308. |
using a nuip specific antibody, we show that expression of nuip protein is mainly colocalized with nurr1 in adult midbrain dopaminergic neurons. |
2008-11-03 |
2023-08-12 |
mouse |
| Jean-Claude Dreher, Andreas Meyer-Lindenberg, Philip Kohn, Karen Faith Berma. Age-related changes in midbrain dopaminergic regulation of the human reward system. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 39. 2008-10-24. PMID:18794529. |
age-related changes in midbrain dopaminergic regulation of the human reward system. |
2008-10-24 |
2023-08-12 |
human |
| Won-Seok Choi, Shane E Kruse, Richard D Palmiter, Zhengui Xi. Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 39. 2008-10-24. PMID:18812510. |
to test this hypothesis genetically, we used a mouse strain lacking functional ndufs4, a gene encoding a subunit required for complete assembly and function of complex i. deletion of the ndufs4 gene abolished complex i activity in midbrain mesencephalic neurons cultured from embryonic day (e) 14 mice, but did not affect the survival of dopaminergic neurons in culture. |
2008-10-24 |
2023-08-12 |
mouse |
| Baek-Soo Han, Lorraine Iacovitti, Taku Katano, Nobutaka Hattori, Wongi Seol, Kwang-Soo Ki. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra. Neuroscience letters. vol 442. issue 3. 2008-10-21. PMID:18634852. |
expression of the lrrk2 gene in the midbrain dopaminergic neurons of the substantia nigra. |
2008-10-21 |
2023-08-12 |
mouse |
| Baek-Soo Han, Lorraine Iacovitti, Taku Katano, Nobutaka Hattori, Wongi Seol, Kwang-Soo Ki. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra. Neuroscience letters. vol 442. issue 3. 2008-10-21. PMID:18634852. |
a hallmark of parkinson's disease (pd) is the progressive loss of the a9 midbrain dopaminergic (mda) neurons in the substantia nigra pars compacta. |
2008-10-21 |
2023-08-12 |
mouse |
| Darcy Litteljohn, Emily N Mangano, Shawn Hayle. Cyclooxygenase-2 deficiency modifies the neurochemical effects, motor impairment and co-morbid anxiety provoked by paraquat administration in mice. The European journal of neuroscience. vol 28. issue 4. 2008-10-20. PMID:18657183. |
parkinson's disease and other motor disorders of midbrain basal ganglia dopaminergic functioning are often characterized by alterations of brainstem and limbic systems with accompanying co-morbid anxiety and depressive symptoms. |
2008-10-20 |
2023-08-12 |
mouse |
| Shankar J Chinta, Julie K Anderse. Redox imbalance in Parkinson's disease. Biochimica et biophysica acta. vol 1780. issue 11. 2008-10-08. PMID:18358848. |
parkinson's disease (pd) is an adult-onset neurodegenerative disorder characterized by preferential loss of dopaminergic neurons in an area of the midbrain called the substantia nigra (sn) along with occurrence of intraneuronal inclusions called lewy bodies. |
2008-10-08 |
2023-08-12 |
Not clear |
| Jaroslaw Maciaczyk, Ilyas Singec, Donata Maciaczyk, Guido Nikkha. Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of human fetal midbrain precursor cells. Experimental neurology. vol 213. issue 2. 2008-10-08. PMID:18652826. |
however, it is poorly understood why midbrain npcs lose their dopaminergic differentiation potential after long-term culture. |
2008-10-08 |
2023-08-12 |
human |
| Yael Niv, Geoffrey Schoenbau. Dialogues on prediction errors. Trends in cognitive sciences. vol 12. issue 7. 2008-09-30. PMID:18567531. |
neural correlates of such prediction-error signals have been observed now in midbrain dopaminergic neurons, striatum, amygdala and even prefrontal cortex, and models incorporating prediction errors have been invoked to explain complex phenomena such as the transition from goal-directed to habitual behavior. |
2008-09-30 |
2023-08-12 |
Not clear |
| Brandon J Aragona, Nathan A Cleaveland, Garret D Stuber, Jeremy J Day, Regina M Carelli, R Mark Wightma. Preferential enhancement of dopamine transmission within the nucleus accumbens shell by cocaine is attributable to a direct increase in phasic dopamine release events. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 35. 2008-09-18. PMID:18753384. |
however, an additional increase in the number phasic release events occurred only within the nac shell, and this increase was eliminated by inactivation of midbrain dopaminergic neurons. |
2008-09-18 |
2023-08-12 |
Not clear |