| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bojana Zupan, Miklos Tot. Inactivation of the maternal fragile X gene results in sensitization of GABAB receptor function in the offspring. The Journal of pharmacology and experimental therapeutics. vol 327. issue 3. 2009-01-05. PMID:18812493. |
the gabaergic system also regulates da release, in part via presynaptic gaba(b) receptors (rs) located on midbrain dopaminergic neurons. |
2009-01-05 |
2023-08-12 |
mouse |
| Wen Ji Yuan, Takao Yasuhara, Tetsuro Shingo, Kenichiro Muraoka, Takashi Agari, Masahiro Kameda, Takashi Uozumi, Naoki Tajiri, Takamasa Morimoto, Meng Jing, Tanefumi Baba, Feifei Wang, Hanbai Leung, Toshihiro Matsui, Yasuyuki Miyoshi, Isao Dat. Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons. BMC neuroscience. vol 9. 2008-12-31. PMID:18671880. |
6-hydroxydopamine (6-ohda), a neurotoxin for dopaminergic neurons, was added to cultured dopaminergic neurons derived from murine embryonal ventral mesencephalon with subsequet administration of edaravone or saline. |
2008-12-31 |
2023-08-12 |
rat |
| Mati Joshua, Avital Adler, Rea Mitelman, Eilon Vaadia, Hagai Bergma. Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 45. 2008-12-31. PMID:18987203. |
midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials. |
2008-12-31 |
2023-08-12 |
monkey |
| Mati Joshua, Avital Adler, Rea Mitelman, Eilon Vaadia, Hagai Bergma. Midbrain dopaminergic neurons and striatal cholinergic interneurons encode the difference between reward and aversive events at different epochs of probabilistic classical conditioning trials. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 45. 2008-12-31. PMID:18987203. |
midbrain dopaminergic neurons (dans) typically increase their discharge rate in response to appetitive predictive cues and outcomes, whereas striatal cholinergic tonically active interneurons (tans) decrease their rate. |
2008-12-31 |
2023-08-12 |
monkey |
| Daniela Omodei, Dario Acampora, Pietro Mancuso, Nilima Prakash, Luca Giovanni Di Giovannantonio, Wolfgang Wurst, Antonio Simeon. Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. Development (Cambridge, England). vol 135. issue 20. 2008-12-22. PMID:18820178. |
anterior-posterior graded response to otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon. |
2008-12-22 |
2023-08-12 |
mouse |
| Ye Ding, Liang L. Lipopolysaccharide preconditioning induces protection against lipopolysaccharide-induced neurotoxicity in organotypic midbrain slice culture. Neuroscience bulletin. vol 24. issue 4. 2008-12-19. PMID:18668149. |
to identify the protective effect of lipopolysaccharide (lps) preconditioning against lps-induced inflammatory damage in dopaminergic neurons of midbrain slice culture and the possible mechanisms. |
2008-12-19 |
2023-08-12 |
Not clear |
| Birgit Liss, Jochen Roepe. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18023878. |
dopaminergic midbrain neurons are involved in many important brain functions including motor control, as well as emotive and cognitive tasks. |
2008-12-18 |
2023-08-12 |
Not clear |
| Birgit Liss, Jochen Roepe. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18023878. |
this bewildering diversity of distinct dopaminergic functions appears to be in contrast to the routinely assumed functional homogeneity of dopaminergic midbrain neurons at the level of individual cells. |
2008-12-18 |
2023-08-12 |
Not clear |
| Birgit Liss, Jochen Roepe. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18023878. |
however, there is increasing evidence for functional diversity as well as plasticity within the population of dopaminergic midbrain neurons. |
2008-12-18 |
2023-08-12 |
Not clear |
| Birgit Liss, Jochen Roepe. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18023878. |
in addition, dopaminergic midbrain neurons are also not homogeneously affected by disease processes, but instead show large differences in their relative vulnerability, especially their susceptibility to cell death in parkinson disease. |
2008-12-18 |
2023-08-12 |
Not clear |
| Birgit Liss, Jochen Roepe. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18023878. |
here, we review recent progress in understanding diversity and flexibility of individual dopaminergic midbrain neurons at molecular and functional levels. |
2008-12-18 |
2023-08-12 |
Not clear |
| J Mena-Segovia, P Winn, J P Bola. Cholinergic modulation of midbrain dopaminergic systems. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18343506. |
cholinergic modulation of midbrain dopaminergic systems. |
2008-12-18 |
2023-08-12 |
Not clear |
| J Mena-Segovia, P Winn, J P Bola. Cholinergic modulation of midbrain dopaminergic systems. Brain research reviews. vol 58. issue 2. 2008-12-18. PMID:18343506. |
brainstem cholinergic neurons are thus in a position to critically influence the activity of dopaminergic neurons in the midbrain, and thereby have a critical role in the expression of behavior. |
2008-12-18 |
2023-08-12 |
Not clear |
| Shih-Ya Hung, Houng-Chi Liou, Kai-Hsiang Kang, Ruey-Meei Wu, Chun-Chiang Wen, Wen-Mei F. Overexpression of heme oxygenase-1 protects dopaminergic neurons against 1-methyl-4-phenylpyridinium-induced neurotoxicity. Molecular pharmacology. vol 74. issue 6. 2008-12-16. PMID:18799798. |
ho-1 overexpression also protected dopaminergic neurons against mpp(+)-induced neurotoxicity in midbrain neuron-glia cocultures. |
2008-12-16 |
2023-08-12 |
human |
| V Bagga, S B Dunnett, R A Fricker-Gate. Ascorbic acid increases the number of dopamine neurons in vitro and in transplants to the 6-OHDA-lesioned rat brain. Cell transplantation. vol 17. issue 7. 2008-12-16. PMID:19044203. |
while the increased number of dopamine neurons observed in our study following ascorbic acid treatment may reflect a selective survival effect, our in vitro results suggest that ascorbic acid may act to increase the number dopamine neurons, both in culture and following transplantation, by stimulating dopaminergic differentiation of neural precursors from the fetal ventral mesencephalon. |
2008-12-16 |
2023-08-12 |
rat |
| Gwenaëlle Le Pen, Laure Sonnier, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs, Alain Prochiant. Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: a new genetic model for Parkinson's disease? Parkinsonism & related disorders. vol 14 Suppl 2. 2008-12-12. PMID:18585951. |
progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for engrailed1: a new genetic model for parkinson's disease? |
2008-12-12 |
2023-08-12 |
mouse |
| Gwenaëlle Le Pen, Laure Sonnier, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs, Alain Prochiant. Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1: a new genetic model for Parkinson's disease? Parkinsonism & related disorders. vol 14 Suppl 2. 2008-12-12. PMID:18585951. |
engrailed1 is a developmental gene of the homeogene family that controls the survival of midbrain dopaminergic neurons throughout life. |
2008-12-12 |
2023-08-12 |
mouse |
| Ya-Chun Huang, Neal A Hessle. Social modulation during songbird courtship potentiates midbrain dopaminergic neurons. PloS one. vol 3. issue 10. 2008-12-12. PMID:18827927. |
social modulation during songbird courtship potentiates midbrain dopaminergic neurons. |
2008-12-12 |
2023-08-12 |
Not clear |
| Martha Carvour, Chunjuan Song, Siddharth Kaul, Vellareddy Anantharam, Anumantha Kanthasamy, Arthi Kanthasam. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991865. |
in this study, n27 cells, a dopaminergic neuronal cell line derived from rat mesencephalon, exposed to low doses of h(2)o(2) (0-30 mum for 12-24 hr) exhibited dose- and time-dependent increases in cytotoxicity and ros generation. |
2008-12-09 |
2023-08-12 |
rat |
| Can Ozan Tan, Daniel Bulloc. A dopamine-acetylcholine cascade: simulating learned and lesion-induced behavior of striatal cholinergic interneurons. Journal of neurophysiology. vol 100. issue 4. 2008-12-05. PMID:18715897. |
whereas tonic activity emerges from intrinsic properties of these neurons, glutamatergic inputs from intralaminar thalamic nuclei and dopaminergic inputs from midbrain are required for genesis of pause responses. |
2008-12-05 |
2023-08-12 |
Not clear |