| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Davide Quarta, Carla Di Francesco, Sergio Melotto, Laura Mangiarini, Christian Heidbreder, Gael Hedo. Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens. Neurochemistry international. vol 54. issue 2. 2009-05-01. PMID:19118592. |
ghs-rs are also expressed in midbrain dopaminergic neurons of the ventral tegmental area (vta) suggesting that ghrelin may modulate the mesolimbic dopamine (da) system. |
2009-05-01 |
2023-08-12 |
rat |
| Dario Greco, Floriana Volpicelli, Antonio Di Lieto, Damiana Leo, Carla Perrone-Capano, Petri Auvinen, Umberto di Porzi. Comparison of gene expression profile in embryonic mesencephalon and neuronal primary cultures. PloS one. vol 4. issue 3. 2009-04-24. PMID:19305503. |
in the mammalian central nervous system (cns) an important contingent of dopaminergic neurons are localized in the substantia nigra and in the ventral tegmental area of the ventral midbrain. |
2009-04-24 |
2023-08-12 |
Not clear |
| Kenta Yamauchi, Shigeki Mizushima, Atsushi Tamada, Nobuhiko Yamamoto, Seiji Takashima, Fujio Murakam. FGF8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3F. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 13. 2009-04-23. PMID:19339600. |
fgf8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3f. |
2009-04-23 |
2023-08-12 |
Not clear |
| Kenta Yamauchi, Shigeki Mizushima, Atsushi Tamada, Nobuhiko Yamamoto, Seiji Takashima, Fujio Murakam. FGF8 signaling regulates growth of midbrain dopaminergic axons by inducing semaphorin 3F. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 13. 2009-04-23. PMID:19339600. |
here, we show that a signaling center located at the midbrain-hindbrain boundary (mhb) regulates the rostrally directed growth of axons from midbrain dopaminergic neurons (mdans). |
2009-04-23 |
2023-08-12 |
Not clear |
| Gerhard Jocham, Tilmann A Klein, Jane Neumann, D Yves von Cramon, Martin Reuter, Markus Ullsperge. Dopamine DRD2 polymorphism alters reversal learning and associated neural activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 12. 2009-04-21. PMID:19321766. |
negative feedback that incurred a change in behavior additionally engaged the ventral striatum and a region of the midbrain consistent with the location of dopaminergic cell groups. |
2009-04-21 |
2023-08-12 |
human |
| Y Kurauchi, A Hisatsune, Y Isohama, H Katsuk. Nitric oxide-cyclic GMP signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression. Neuroscience. vol 158. issue 2. 2009-04-15. PMID:18996444. |
nitric oxide-cyclic gmp signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression. |
2009-04-15 |
2023-08-12 |
rat |
| Y Kurauchi, A Hisatsune, Y Isohama, H Katsuk. Nitric oxide-cyclic GMP signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression. Neuroscience. vol 158. issue 2. 2009-04-15. PMID:18996444. |
activation of microglia by interferon-gamma (ifn-gamma) followed by lipopolysaccharide (lps) caused dopaminergic cell death in rat midbrain slice cultures, which was dependent on no production. |
2009-04-15 |
2023-08-12 |
rat |
| Margaret A Cooper, Kazuto Kobayashi, Renping Zho. Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways. Developmental neurobiology. vol 69. issue 1. 2009-04-15. PMID:19003794. |
ephrin-a5 regulates the formation of the ascending midbrain dopaminergic pathways. |
2009-04-15 |
2023-08-12 |
mouse |
| Margaret A Cooper, Kazuto Kobayashi, Renping Zho. Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways. Developmental neurobiology. vol 69. issue 1. 2009-04-15. PMID:19003794. |
dopaminergic neurons from the substantia nigra and the ventral tegmental area of the midbrain project to the caudate/putamen and nucleus accumbens, respectively, establishing the mesostriatal and the mesolimbic pathways. |
2009-04-15 |
2023-08-12 |
mouse |
| Margaret A Cooper, Kazuto Kobayashi, Renping Zho. Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways. Developmental neurobiology. vol 69. issue 1. 2009-04-15. PMID:19003794. |
in the current study, the epha5 receptor and its corresponding ligand, ephrin-a5, were shown to regulate dopaminergic axon outgrowth and influence the formation of the midbrain dopaminergic pathways. |
2009-04-15 |
2023-08-12 |
mouse |
| Margaret A Cooper, Kazuto Kobayashi, Renping Zho. Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways. Developmental neurobiology. vol 69. issue 1. 2009-04-15. PMID:19003794. |
these observations indicate that the interactions between ephrin-a ligands and epha receptors promote growth and targeting of the midbrain dopaminergic axons to the striatum. |
2009-04-15 |
2023-08-12 |
mouse |
| Andreas Bender, Rachel-Maria Schwarzkopf, Anja McMillan, Kim J Krishnan, Gabriele Rieder, Manuela Neumann, Matthias Elstner, Douglas M Turnbull, Thomas Klopstoc. Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions. Journal of neurology. vol 255. issue 8. 2009-04-14. PMID:18604467. |
dopaminergic midbrain neurons are the prime target for mitochondrial dna deletions. |
2009-04-14 |
2023-08-12 |
human |
| Alexander J Whitworth, Jeffrey R Lee, Venus M-W Ho, Robert Flick, Ruhena Chowdhury, G Angus McQuibba. Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Disease models & mechanisms. vol 1. issue 2-3. 2009-04-14. PMID:19048081. |
parkinson's disease (pd) is a common neurodegenerative disorder caused by loss of midbrain dopaminergic neurons, the pathogenetic mechanisms of which remain unclear. |
2009-04-14 |
2023-08-12 |
drosophila_melanogaster |
| David H Zald, Ronald L Cowan, Patrizia Riccardi, Ronald M Baldwin, M Sib Ansari, Rui Li, Evan S Shelby, Clarence E Smith, Maureen McHugo, Robert M Kessle. Midbrain dopamine receptor availability is inversely associated with novelty-seeking traits in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 53. 2009-04-09. PMID:19118170. |
we speculate that the lower midbrain (auto)receptor availability seen in high novelty seekers leads to accentuated dopaminergic responses to novelty and other conditions that induce dopamine release. |
2009-04-09 |
2023-08-12 |
human |
| Chao Guo, Hai-Yan Qiu, Ming Shi, Ying Huang, Randy L Johnson, Marcelo Rubinstein, Sheng-Di Chen, Yu-Qiang Din. Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 52. 2009-04-08. PMID:19109492. |
lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. |
2009-04-08 |
2023-08-12 |
mouse |
| Chao Guo, Hai-Yan Qiu, Ming Shi, Ying Huang, Randy L Johnson, Marcelo Rubinstein, Sheng-Di Chen, Yu-Qiang Din. Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 52. 2009-04-08. PMID:19109492. |
the lim homeodomain transcription factor lmx1b has been suggested to be required for the differentiation of midbrain dopaminergic (mda) neurons. |
2009-04-08 |
2023-08-12 |
mouse |
| Yong Ren, Houbo Jiang, Fang Yang, Kazuhiro Nakaso, Jian Fen. Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. The Journal of biological chemistry. vol 284. issue 6. 2009-04-06. PMID:19074146. |
such mutations produced truncated parkin proteins lacking any microtubule binding domain and prevented parkin from protecting midbrain dopaminergic neurons against microtubule-depolymerizing toxins such as rotenone or colchicine. |
2009-04-06 |
2023-08-12 |
Not clear |
| Yong Ren, Houbo Jiang, Fang Yang, Kazuhiro Nakaso, Jian Fen. Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. The Journal of biological chemistry. vol 284. issue 6. 2009-04-06. PMID:19074146. |
consistent with these, blocking map kinase activation in midbrain dopaminergic neurons by knocking down map kinase kinases (mkk) significantly reduced the selective toxicity of rotenone or colchicine. |
2009-04-06 |
2023-08-12 |
Not clear |
| Yong Ren, Houbo Jiang, Fang Yang, Kazuhiro Nakaso, Jian Fen. Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation. The Journal of biological chemistry. vol 284. issue 6. 2009-04-06. PMID:19074146. |
thus, the results suggest that parkin protects midbrain dopaminergic neurons against microtubule-depolymerizing pd toxins such as rotenone by stabilizing microtubules to attenuate map kinase activation. |
2009-04-06 |
2023-08-12 |
Not clear |
| Johannes Schwar. Developmental perspectives on human midbrain-derived neural stem cells. Parkinsonism & related disorders. vol 13 Suppl 3. 2009-04-01. PMID:18267285. |
the replacement of dopaminergic neurons in patients with parkinson's disease via implantation of embryonic midbrain tissue was taken from animal experiments to clinical applications showing limited efficacy. |
2009-04-01 |
2023-08-12 |
human |