| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
if a dopamine uptake inhibitor, nomifensine, was added to the ringer solution used to dialyse the probe, the s.c. administration of both acute and subchronic nicotine (0.4 mg kg-1) resulted in significant increases (p less than 0.05) in the dopamine concentration in the dialysate. |
1992-09-22 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
under these conditions, pretreatment with nicotine prior to the test day prolonged (p less than 0.05) the dopamine response to a challenge dose of nicotine.6. |
1992-09-22 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
the results of this study support the conclusion that the enhanced locomotor response to nicotine observed in animals pretreated with the drug prior to the test day is associated with potentiation of its effects on dopamine secretion in the nac. |
1992-09-22 |
2023-08-11 |
rat |
| T H Svensson, J Grenhoff, C S Tung, G Chouvet, J M Mathé, S Muras. The psychopharmacology of nicotine and its effects on CNS dopamine neurones. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1498950. |
the psychopharmacology of nicotine and its effects on cns dopamine neurones. |
1992-09-14 |
2023-08-11 |
Not clear |
| G Di Chiar. Mesolimbic dopamine and incentive properties of nicotine. Clinical neuropharmacology. vol 15 Suppl 1 Pt A. 1992-09-14. PMID:1498951. |
mesolimbic dopamine and incentive properties of nicotine. |
1992-09-14 |
2023-08-11 |
Not clear |
| J H Carlson, S L Foot. Oscillation of interspike interval length in substantia nigra dopamine neurons: effects of nicotine and the dopaminergic D2 agonist LY 163502 on electrophysiological activity. Synapse (New York, N.Y.). vol 11. issue 3. 1992-08-24. PMID:1636152. |
oscillation of interspike interval length in substantia nigra dopamine neurons: effects of nicotine and the dopaminergic d2 agonist ly 163502 on electrophysiological activity. |
1992-08-24 |
2023-08-11 |
rat |
| D G Kirch, T R Taylor, I Creese, S X Xu, R J Wyat. Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors. The Journal of pharmacy and pharmacology. vol 44. issue 2. 1992-08-19. PMID:1352822. |
effect of chronic nicotine treatment and withdrawal on rat striatal d1 and d2 dopamine receptors. |
1992-08-19 |
2023-08-11 |
rat |
| D G Kirch, T R Taylor, I Creese, S X Xu, R J Wyat. Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors. The Journal of pharmacy and pharmacology. vol 44. issue 2. 1992-08-19. PMID:1352822. |
the effects on rat striatal dopamine receptors after chronic nicotine administration (3 and 12 mg kg-1 day-1), and after withdrawal from chronic nicotine (12 mg kg-1 day-1), were studied. |
1992-08-19 |
2023-08-11 |
rat |
| D G Kirch, T R Taylor, I Creese, S X Xu, R J Wyat. Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors. The Journal of pharmacy and pharmacology. vol 44. issue 2. 1992-08-19. PMID:1352822. |
although nicotine has been shown to affect nigrostriatal dopamine release, chronic treatment does not appear to alter overall striatal dopaminergic receptor binding parameters. |
1992-08-19 |
2023-08-11 |
rat |
| E Toth, H Sershen, A Hashim, E S Vizi, A Lajth. Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid. Neurochemical research. vol 17. issue 3. 1992-08-05. PMID:1352387. |
following nicotine administration the extracellular concentration of dopamine increased in all regions except cerebellum; serotonin increased in cingulate and frontal cortex; and norepinephrine increased in substantia nigra, cingulate cortex, and pontine nucleus. |
1992-08-05 |
2023-08-11 |
rat |
| W A Corrigall, K B Franklin, K M Coen, P B Clark. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology. vol 107. issue 2-3. 1992-07-30. PMID:1615127. |
these data demonstrate that the reinforcing effects of nicotine occur within the central nervous system, and that the mesolimbic dopamine projection plays an important role in these effects. |
1992-07-30 |
2023-08-11 |
rat |
| L G Harsing, H Sershen, A Lajth. Dopamine efflux from striatum after chronic nicotine: evidence for autoreceptor desensitization. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1351932. |
dopamine efflux from striatum after chronic nicotine: evidence for autoreceptor desensitization. |
1992-07-24 |
2023-08-11 |
mouse |
| L G Harsing, H Sershen, A Lajth. Dopamine efflux from striatum after chronic nicotine: evidence for autoreceptor desensitization. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1351932. |
we examined the effect of chronic nicotine treatment on dopaminergic activity by measuring the effects of d1 and d2 dopamine (da) receptor agonists and antagonists on tritium release from mouse striatum preloaded with [3h]da. |
1992-07-24 |
2023-08-11 |
mouse |
| G Sedvall, L Farde, H Nybäck, S Pauli, A Persson, I Savic, F A Wiese. Recent advances in psychiatric brain imaging. Acta radiologica. Supplementum. vol 374. 1992-07-17. PMID:1966956. |
the present communication describes the use of 11c-sch 23390 and 11c-raclopride for the analysis of d1 and d2 dopamine receptors, the benzodiazepine (bz) antagonist 11c-ro 15-1788 for benzodiazepine receptors and 11c-nicotine for nicotine receptors. |
1992-07-17 |
2023-08-11 |
human |
| N T Sandor, T Zelles, J Kiss, H Sershen, A Torocsik, A Lajtha, E S Viz. Effect of nicotine on dopaminergic-cholinergic interaction in the striatum. Brain research. vol 567. issue 2. 1992-07-10. PMID:1817734. |
since the release of ach in the striatum is tonically inhibited by endogenous dopamine and nicotine enhances the release of dopamine, we studied the release of ach when the dopaminergic input was impaired. |
1992-07-10 |
2023-08-11 |
rat |
| L P Dwoskin, L L Leibee, A L Jewell, Z X Fang, P A Crook. Inhibition of [3H]dopamine uptake into rat striatal slices by quaternary N-methylated nicotine metabolites. Life sciences. vol 50. issue 25. 1992-07-02. PMID:1593921. |
inhibition of [3h]dopamine uptake into rat striatal slices by quaternary n-methylated nicotine metabolites. |
1992-07-02 |
2023-08-11 |
rat |
| L P Dwoskin, L L Leibee, A L Jewell, Z X Fang, P A Crook. Inhibition of [3H]dopamine uptake into rat striatal slices by quaternary N-methylated nicotine metabolites. Life sciences. vol 50. issue 25. 1992-07-02. PMID:1593921. |
the effects of quaternary n-methylated nicotine derivatives were examined on in vitro uptake of [3h]dopamine ([3h]da) in rat striatal slices. |
1992-07-02 |
2023-08-11 |
rat |
| M D Schechter, S M Meeha. Further evidence for the mechanisms that may mediate nicotine discrimination. Pharmacology, biochemistry, and behavior. vol 41. issue 4. 1992-06-30. PMID:1534414. |
once criterion performance was attained, dose-response experiments indicated an ed50 value of 0.1 mg/kg and subsequent time course experiments showed a maximal effect between 10 and 30 min postadministration with a return to saline-like responding at 2 h. pretreatment with the presynaptic dopamine release inhibitors cgs 10746b (30 mg/kg), as well as with the dihydropyridine calcium blocker isradipine (15 mg/kg), each produced a significant blockade of nicotine discrimination. |
1992-06-30 |
2023-08-11 |
rat |
| M D Schechter, S M Meeha. Further evidence for the mechanisms that may mediate nicotine discrimination. Pharmacology, biochemistry, and behavior. vol 41. issue 4. 1992-06-30. PMID:1534414. |
thus, drugs that interfere with calcium influx, viz., isradipine, or with dopamine release (cgs 10746b) also interfere with nicotine discrimination and these results suggest that calcium influx and dopamine release may be necessary conditions for nicotine discrimination. |
1992-06-30 |
2023-08-11 |
rat |
| A M Janson, J J Meana, M Goiny, M Herrera-Marschit. Chronic nicotine treatment counteracts the decrease in extracellular neostriatal dopamine induced by a unilateral transection at the mesodiencephalic junction in rats: a microdialysis study. Neuroscience letters. vol 134. issue 1. 1992-06-24. PMID:1815152. |
chronic nicotine treatment counteracts the decrease in extracellular neostriatal dopamine induced by a unilateral transection at the mesodiencephalic junction in rats: a microdialysis study. |
1992-06-24 |
2023-08-11 |
rat |