| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T H Svensson, J Grenhof. [Neuropharmacology of smoking: basic research opens new therapeutic possibilities]. Lakartidningen. vol 88. issue 22. 1991-07-24. PMID:2051876. |
nicotine acts via nicotinic receptors, and its dependence-promoting properties appear to be chiefly mediated by stimulation of noradrenaline and dopamine neurons in the brain, which may help to explain the excessive tobacco consumption associated with certain psychiatric disorders. |
1991-07-24 |
2023-08-11 |
Not clear |
| G W Paulson, N Dadmeh. Is there a premorbid personality typical for Parkinson's disease? Neurology. vol 41. issue 5 Suppl 2. 1991-07-10. PMID:2041597. |
it has been suggested that nicotine and its byproducts are not actually protective against pd, and it could be postulated that higher-than-average intrinsic dopamine may facilitate addiction. |
1991-07-10 |
2023-08-11 |
Not clear |
| P Huettl, G A Gerhardt, M D Browning, J M Masseran. Effects of dopamine receptor agonists and antagonists on catecholamine release in bovine chromaffin cells. The Journal of pharmacology and experimental therapeutics. vol 257. issue 2. 1991-06-24. PMID:1674528. |
in the present study we have evaluated the effects of dopamine d2 agonists and antagonists on the release of endogenous norepinephrine and epinephrine stimulated by 50 microm nicotine in isolated bovine chromaffin cells in order to investigate whether isolated bovine chromaffin cells may contain functional dopamine d2 receptors. |
1991-06-24 |
2023-08-11 |
cattle |
| D J Feller, J C Crabb. Effect of neurotransmitter-selective drugs in mice selected for differential sensitivity to the hypothermic actions of ethanol. The Journal of pharmacology and experimental therapeutics. vol 256. issue 3. 1991-04-24. PMID:1672379. |
the drugs administered were the opiate drugs morphine, levorphanol and u50488h, the dopamine agonists apomorphine, ly171535 and skf38393, the dopamine antagonist chlorpromazine, the alpha adrenergic agonist st587, the cholinergic agonist nicotine and amphetamine, which increases the release of catecholamines. |
1991-04-24 |
2023-08-11 |
mouse |
| S Lahiri, A Mokashi, M Shirahata, S Androniko. Chemical respiratory control in chronically hyperoxic cats. Respiration physiology. vol 82. issue 2. 1991-04-16. PMID:2075296. |
the normal stimulatory effects of intravenous nicotine and inhibitory effect of dopamine on carotid chemo-receptor activity and ventilation were preserved in the nh cats. |
1991-04-16 |
2023-08-11 |
rat |
| M P Brazell, S N Mitchell, M H Joseph, J A Gra. Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat: comparison with caudate-putamen. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2293060. |
acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat: comparison with caudate-putamen. |
1991-04-09 |
2023-08-11 |
rat |
| M P Brazell, S N Mitchell, M H Joseph, J A Gra. Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat: comparison with caudate-putamen. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2293060. |
nicotine stimulated release of dopamine only in the nucleus accumbens, measured using dialysis. |
1991-04-09 |
2023-08-11 |
rat |
| M P Brazell, S N Mitchell, M H Joseph, J A Gra. Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat: comparison with caudate-putamen. Neuropharmacology. vol 29. issue 12. 1991-04-09. PMID:2293060. |
these results show that acute administration of nicotine stimulated release of dopamine in the nucleus accumbens and increased the levels of dopac and ascorbic acid in the nucleus accumbens and caudate-putamen. |
1991-04-09 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
nicotine indirectly inhibits [3h]dopamine uptake at concentrations that do not directly promote [3h]dopamine release in rat striatum. |
1991-02-26 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
unlike other dopamine uptake inhibitors, however, nicotine inhibited only 50% of the total uptake. |
1991-02-26 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
in the presence of 1 nm nicotine, the residual [3h]dopamine uptake was less sensitive to inhibition by cocaine than uptake in the absence of nicotine. |
1991-02-26 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
nicotine did not compete against the binding of [3h]gbr 12935, a selective dopamine uptake inhibitor. |
1991-02-26 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
thus, the effect of nicotine on dopamine uptake appears to be mediated by a receptor similar to the nicotinic acetylcholine receptor. |
1991-02-26 |
2023-08-11 |
rat |
| S Izenwasser, H M Jacocks, J G Rosenberger, B M Co. Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1988558. |
these receptors do not seem to be on the terminals that are accumulating dopamine, however, since tetrodotoxin prevented the effect of nicotine on [3h]dopamine uptake and nicotine had no effect on uptake in a synaptosomal preparation. |
1991-02-26 |
2023-08-11 |
rat |
| T Leikola-Pelho, J Heinämäki, I Laakso, L Ahte. Chronic nicotine treatment changes differentially the effects of acute nicotine on the three main dopamine metabolites in mouse striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 4. 1991-01-22. PMID:2255334. |
chronic nicotine treatment changes differentially the effects of acute nicotine on the three main dopamine metabolites in mouse striatum. |
1991-01-22 |
2023-08-11 |
mouse |
| T Leikola-Pelho, J Heinämäki, I Laakso, L Ahte. Chronic nicotine treatment changes differentially the effects of acute nicotine on the three main dopamine metabolites in mouse striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 4. 1991-01-22. PMID:2255334. |
the effect of chronic treatment with nicotine on striatal dopamine metabolism was studied in mice by measuring the striatal concentrations of dopamine and its metabolites 3-methoxytyramine (3-mt), 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva). |
1991-01-22 |
2023-08-11 |
mouse |
| T Leikola-Pelho, J Heinämäki, I Laakso, L Ahte. Chronic nicotine treatment changes differentially the effects of acute nicotine on the three main dopamine metabolites in mouse striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 4. 1991-01-22. PMID:2255334. |
at an ambient temperature of 20-22 degrees c, acute nicotine treatment induced marked hypothermia (-5.2 to -6.7 degrees c) in both chronic nicotine treated and control mice, an effect that was prevented by elevating the ambient temperature to 32-34 degrees c. chronic nicotine treatment did not per se alter striatal dopamine metabolism. |
1991-01-22 |
2023-08-11 |
mouse |
| T Leikola-Pelho, J Heinämäki, I Laakso, L Ahte. Chronic nicotine treatment changes differentially the effects of acute nicotine on the three main dopamine metabolites in mouse striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 4. 1991-01-22. PMID:2255334. |
acute nicotine administration altered the striatal dopamine metabolism in a temperature-dependent manner. |
1991-01-22 |
2023-08-11 |
mouse |
| P P Rowell, S Wonnacot. Evidence for functional activity of up-regulated nicotine binding sites in rat striatal synaptosomes. Journal of neurochemistry. vol 55. issue 6. 1990-12-20. PMID:2230812. |
in this study, the effects of 1-week administration of the potent nicotinic agonist, (+)-anatoxin-a (96 nmol/day via osmotic minipumps), was assessed on [3h]nicotine binding and [3h]dopamine uptake and release in rat striatal synaptosomes. |
1990-12-20 |
2023-08-11 |
rat |
| P P Rowell, S Wonnacot. Evidence for functional activity of up-regulated nicotine binding sites in rat striatal synaptosomes. Journal of neurochemistry. vol 55. issue 6. 1990-12-20. PMID:2230812. |
there was a 43% increase in the activity of 3 microm nicotine to release [3h]dopamine from synaptosomes of anatoxin-treated animals, but the release induced by 20 mm k+ depolarization was unaffected. |
1990-12-20 |
2023-08-11 |
rat |