| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y K Fun. Effects of chronic nicotine pretreatment on (+)-amphetamine and nicotine-induced synthesis and release of [3H]dopamine from [3H]tyrosine in rat nucleus accumbens. The Journal of pharmacy and pharmacology. vol 41. issue 1. 1989-06-20. PMID:2565971. |
effects of chronic nicotine pretreatment on (+)-amphetamine and nicotine-induced synthesis and release of [3h]dopamine from [3h]tyrosine in rat nucleus accumbens. |
1989-06-20 |
2023-08-11 |
rat |
| Y K Fun. Effects of chronic nicotine pretreatment on (+)-amphetamine and nicotine-induced synthesis and release of [3H]dopamine from [3H]tyrosine in rat nucleus accumbens. The Journal of pharmacy and pharmacology. vol 41. issue 1. 1989-06-20. PMID:2565971. |
pretreatment of animals with nicotine increased the endogenous level of dopamine. |
1989-06-20 |
2023-08-11 |
rat |
| Y K Fun. Effects of chronic nicotine pretreatment on (+)-amphetamine and nicotine-induced synthesis and release of [3H]dopamine from [3H]tyrosine in rat nucleus accumbens. The Journal of pharmacy and pharmacology. vol 41. issue 1. 1989-06-20. PMID:2565971. |
the ability of (+)-amphetamine to stimulate formation and release of [3h]dopamine from [3h]tyrosine was greatly potentiated in tissue slices from the nucleus accumbens of rats pretreated with nicotine. |
1989-06-20 |
2023-08-11 |
rat |
| Y K Fun. Effects of chronic nicotine pretreatment on (+)-amphetamine and nicotine-induced synthesis and release of [3H]dopamine from [3H]tyrosine in rat nucleus accumbens. The Journal of pharmacy and pharmacology. vol 41. issue 1. 1989-06-20. PMID:2565971. |
furthermore, nicotine was effective in stimulating the formation and release of from [3h]dopamine from [3h]tyrosine in tissue slices from chronic nicotine-treated animals. |
1989-06-20 |
2023-08-11 |
rat |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
action of nicotine on accumbens dopamine and attenuation with repeated administration. |
1989-06-20 |
2023-08-11 |
rat |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
ten minutes after nicotine was given to rats that had previously received only saline the levels of dopamine and its metabolite dopac indicated an increase in dopamine turnover in the nucleus accumbens. |
1989-06-20 |
2023-08-11 |
rat |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
twenty-four hours after the last nicotine injection the levels of dopamine and its metabolites indicated a sustained decrease in dopamine turnover in the accumbens induced by repeated administration. |
1989-06-20 |
2023-08-11 |
rat |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
following repeated nicotine a nicotine challenge still induced an acute increase in dopamine turnover in the accumbens, but the response was less than in animals not previously given nicotine. |
1989-06-20 |
2023-08-11 |
rat |
| H Sershen, A Hashim, H L Wiener, A Lajth. Effect of chronic oral nicotine on dopaminergic function in the MPTP-treated mouse. Neuroscience letters. vol 93. issue 2-3. 1989-05-16. PMID:3266524. |
terminal recovery, as measured by the rate of recovery in the level of striatal dopamine, was not affected by nicotine. |
1989-05-16 |
2023-08-11 |
mouse |
| D Jovanović-Mićić, M Strbac, S K Krstić, N Japundzić, R Samardzić, D B Belesli. Ablation of the area postrema and emesis. Metabolic brain disease. vol 4. issue 1. 1989-05-12. PMID:2704346. |
the emetic action of dopamine, norepinephrine, epinephrine, nicotine, dimethylphenyl-piperazinium (dmpp), and 4-m-chlorophenylcarbamoyloxy-2-butynyltrimethylammonium (mcn-a-343) injected intracerebroventricularly (i.c.v.) |
1989-05-12 |
2023-08-11 |
cat |
| D Jovanović-Mićić, M Strbac, S K Krstić, N Japundzić, R Samardzić, D B Belesli. Ablation of the area postrema and emesis. Metabolic brain disease. vol 4. issue 1. 1989-05-12. PMID:2704346. |
ed50 values (mg) were as follows: nicotine, 0.011; epinephrine, 0.047; norepinephrine, 0.57; dmpp, 0.9; dopamine, 1.66; and mcn-a-343, 4.42. |
1989-05-12 |
2023-08-11 |
cat |
| D Jovanović-Mićić, M Strbac, S K Krstić, N Japundzić, R Samardzić, D B Belesli. Ablation of the area postrema and emesis. Metabolic brain disease. vol 4. issue 1. 1989-05-12. PMID:2704346. |
dopamine, norepinephrine, epinephrine, nicotine, and dmpp. |
1989-05-12 |
2023-08-11 |
cat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
it has been postulated that addiction to nicotine is mediated by dopamine release in the mesolimbic system. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
it is possible that nicotine might act directly on the dopamine terminals to release dopamine. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
nicotine increased extracellular dopamine in a dose-related manner. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
systemic injection of the nicotine antagonist mecamylamine blocked the dopamine increase induced by local nicotine. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
these results suggest that nicotine releases dopamine by a local action in the nucleus accumbens terminal area of the mesolimbic system. |
1989-04-28 |
2023-08-11 |
rat |
| J C Mifsud, L Hernandez, B G Hoebe. Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis. Brain research. vol 478. issue 2. 1989-04-28. PMID:2924134. |
presynaptic induction of dopamine release might play a role in nicotine addiction. |
1989-04-28 |
2023-08-11 |
rat |
| U Ribary, W Lichtensteige. Effects of acute and chronic prenatal nicotine treatment on central catecholamine systems of male and female rat fetuses and offspring. The Journal of pharmacology and experimental therapeutics. vol 248. issue 2. 1989-04-03. PMID:2918480. |
a single injection of nicotine (1 mg/kg s.c.) to urethane-anesthetized time-pregnant dams at gestational day (gd) 21 increased dopamine, 3,4-dihydroxyphenylacetic acid and homovanillic acid (determined by radioenzymatic assay and high-performance liquid chromatography with electrochemical detection, respectively) in male and female fetal forebrain within 30 min. |
1989-04-03 |
2023-08-11 |
rat |