| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D G Kirch, A M Alho, R J Wyat. Hypothesis: a nicotine-dopamine interaction linking smoking with Parkinson's disease and tardive dyskinesia. Cellular and molecular neurobiology. vol 8. issue 3. 1989-03-29. PMID:3066487. |
although acute doses of nicotine have been shown to facilitate dopamine release, recent data indicate that chronic nicotine treatment may actually decrease cns dopamine turnover in the striatum. |
1989-03-29 |
2023-08-11 |
Not clear |
| D G Kirch, A M Alho, R J Wyat. Hypothesis: a nicotine-dopamine interaction linking smoking with Parkinson's disease and tardive dyskinesia. Cellular and molecular neurobiology. vol 8. issue 3. 1989-03-29. PMID:3066487. |
in this hypothetical scheme, individuals who are given neuroleptics and who also are smokers may develop a greater degree of dopamine receptor supersensitivity due to combined receptor blockade by neuroleptics and a decrease in cns dopamine turnover caused by nicotine, resulting in an increased prevalence of tardive dyskinesia in this group. |
1989-03-29 |
2023-08-11 |
Not clear |
| J Grenhoff, T H Svensso. Selective stimulation of limbic dopamine activity by nicotine. Acta physiologica Scandinavica. vol 133. issue 4. 1989-03-27. PMID:3147576. |
selective stimulation of limbic dopamine activity by nicotine. |
1989-03-27 |
2023-08-11 |
Not clear |
| A M Janson, K Fuxe, E Sundström, L F Agnati, M Goldstei. Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse. Acta physiologica Scandinavica. vol 132. issue 4. 1989-03-27. PMID:3265840. |
chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse. |
1989-03-27 |
2023-08-11 |
mouse |
| Y K Fung, Y S La. Receptor mechanisms of nicotine-induced locomotor hyperactivity in chronic nicotine-treated rats. European journal of pharmacology. vol 152. issue 3. 1989-03-16. PMID:3220106. |
in rats which were pretreated with nicotine for 5 days, there was a significant increase in the nicotine-stimulated locomotor response which was associated with an increase in the number of l-[3h]nicotine binding sites and also with an elevated dopamine (da) level in the striatum. |
1989-03-16 |
2023-08-11 |
rat |
| H Haikala, L Ahte. Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 2. 1988-12-21. PMID:3185744. |
the ability of nicotinic receptor blockers, mecamylamine and pempidine, to antagonize the changes in striatal dopamine (da) metabolism induced by repeated nicotine administration was studied. |
1988-12-21 |
2023-08-11 |
mouse |
| T Wichmann, K Stark. Uptake, release, and modulation of release of noradrenaline in rabbit superior colliculus. Neuroscience. vol 26. issue 2. 1988-11-23. PMID:2845297. |
the release of [3h]noradrenaline is modulated through alpha 2-adrenoceptors as well as dopamine d2-receptors, opioid kappa-receptors and nicotine and muscarine receptors. |
1988-11-23 |
2023-08-11 |
rabbit |
| V Coiro, E Roti, L d'Amato, A Alboni, E Gardini, M Salvi, G Cersosimo, L Bianconi, G Zanardi, A Bacchi-Moden. Effect of bromocriptine on neurophysin secretion in pregnant women in labour. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 2. issue 1. 1988-11-21. PMID:3177010. |
in order to determine whether dopamine plays a role in the control of neuropituitary function in pregnant women during labour, blood levels of nicotine (nsn)- and estrogen (esn)-stimulated neurophysins were measured in 119 women treated orally with placebo (n = 59, control group) or 5 mg bromocriptine, a potent dopaminergic receptor agonist (n = 60, experimental group). |
1988-11-21 |
2023-08-11 |
Not clear |
| G Di Chiara, A Imperat. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 14. 1988-08-24. PMID:2899326. |
drugs abused by humans (e.g., opiates, ethanol, nicotine, amphetamine, and cocaine) increased extracellular dopamine concentrations in both areas, but especially in the accumbens, and elicited hypermotility at low doses. |
1988-08-24 |
2023-08-11 |
rat |
| E A Debler, A Hashim, A Lajtha, H Sershe. Ascorbic acid and striatal transport of [3H] 1-methyl-4-phenylpyridine (MPP+) and [3H] dopamine. Life sciences. vol 42. issue 25. 1988-08-03. PMID:3260319. |
nicotine, its metabolites, and other tobacco alkaloids are weak inhibitors (ic50 greater than 1 mm) except 4-phenylpyridine and lobeline, which are moderate inhibitors (ic50 = 3 to 40 um) of both [3h] dopamine and [3h] mpp+ uptake. |
1988-08-03 |
2023-08-11 |
mouse |
| H Ghazi, N N Osborn. Agonist-induced stimulation of inositol phosphates in primary rabbit retinal cultures. Journal of neurochemistry. vol 50. issue 6. 1988-06-28. PMID:2897428. |
in contrast, dopamine, nicotine, isoproterenol, clonidine, 8-oh-dipropylaminotetralin, and gamma-aminobutyric acid were ineffective. |
1988-06-28 |
2023-08-11 |
rabbit |
| M A Reilly, E P Lapin, H S Maker, A Lajth. Chronic nicotine administration increases binding of [3H]domperidone in rat nucleus accumbens. Journal of neuroscience research. vol 18. issue 4. 1988-04-01. PMID:3437476. |
it is concluded that chronic nicotine administration may have a suppressant effect on central nervous system release of dopamine that in pre-parkinsonian persons causes an aversion to the effects of smoking. |
1988-04-01 |
2023-08-11 |
rat |
| D C Wan, D A Powis, P D Marley, B G Livet. Effects of alpha- and beta-adrenoceptor agonists and antagonists on ATP and catecholamine release and desensitization of the nicotinic response in bovine adrenal chromaffin cells. Biochemical pharmacology. vol 37. issue 4. 1988-03-24. PMID:3342103. |
atp release from freshly isolated cells by 5 microm nicotine was only weakly inhibited by adrenaline and noradrenaline and even then required high concentrations (greater than 500 microm), while dopamine (1 microm-1 mm) and isoproterenol (100 microm) had no effect. |
1988-03-24 |
2023-08-11 |
cattle |
| R A Wis. The role of reward pathways in the development of drug dependence. Pharmacology & therapeutics. vol 35. issue 1-2. 1988-02-20. PMID:3321101. |
ethanol, nicotine, caffeine and phencyclidine stimulate both locomotor activity and dopamine turnover, but their sites of interaction with reward pathways have not yet been identified. |
1988-02-20 |
2023-08-11 |
Not clear |
| M Shirahata, S Andronikou, S Lahir. Differential effects of oligomycin on carotid chemoreceptor responses to O2 and CO2 in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 63. issue 5. 1988-01-27. PMID:3121579. |
in addition, oligomycin administered into the blood with close intra-arterial injection produced similar differential blockade of o2 and co2 chemoreception, preserving the nicotine and dopamine effects. |
1988-01-27 |
2023-08-11 |
cat |
| M Shirahata, S Andronikou, S Lahir. Differential effects of oligomycin on carotid chemoreceptor responses to O2 and CO2 in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 63. issue 5. 1988-01-27. PMID:3121579. |
this study confirmed the previous findings and provided new evidence showing that 1) the responses of carotid chemoreceptor to o2 and co2 were separable by oligomycin due to the inhibition of oxidative phosphorylation and 2) the responses to nicotine and dopamine were intact even after blockade of o2 response. |
1988-01-27 |
2023-08-11 |
cat |
| H Sershen, A Hashim, A Lajth. Behavioral and biochemical effects of nicotine in an MPTP-induced mouse model of Parkinson's disease. Pharmacology, biochemistry, and behavior. vol 28. issue 2. 1988-01-13. PMID:3500479. |
this study examined the effects of nicotine on locomotor activity and on the level of dopamine (da) and its metabolites 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in the striatum and olfactory tubercle of mice that had been treated with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1988-01-13 |
2023-08-11 |
mouse |
| G Mereu, K W Yoon, V Boi, G L Gessa, L Naes, T C Westfal. Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine. European journal of pharmacology. vol 141. issue 3. 1987-12-16. PMID:3666033. |
nicotine on the single unit activity of midbrain dopamine (da) neurons was studied in rats under either local or general anesthesia. |
1987-12-16 |
2023-08-11 |
rat |
| P P Rowell, L A Carr, A C Garne. Stimulation of [3H]dopamine release by nicotine in rat nucleus accumbens. Journal of neurochemistry. vol 49. issue 5. 1987-11-23. PMID:2889800. |
stimulation of [3h]dopamine release by nicotine in rat nucleus accumbens. |
1987-11-23 |
2023-08-11 |
rat |
| P P Rowell, L A Carr, A C Garne. Stimulation of [3H]dopamine release by nicotine in rat nucleus accumbens. Journal of neurochemistry. vol 49. issue 5. 1987-11-23. PMID:2889800. |
in this investigation, the effect of nicotine on the release of [3h]dopamine in the nucleus accumbens of the rat was studied. |
1987-11-23 |
2023-08-11 |
rat |