| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Watano, K Nakazawa, T Obama, M Mori, K Inoue, K Fujimori, A Takanak. Non-competitive antagonism by hirsuteine of nicotinic receptor-mediated dopamine release from rat pheochromocytoma cells. Japanese journal of pharmacology. vol 61. issue 4. 1993-08-03. PMID:8320880. |
hirsuteine did not produce a parallel shift of the concentration-response relationship curve for nicotine, but reduced maximal dopamine release. |
1993-08-03 |
2023-08-12 |
rat |
| R L Siblerud, E Kienholz, J Mot. Evidence that mercury from silver dental fillings may be an etiological factor in smoking. Toxicology letters. vol 68. issue 3. 1993-07-19. PMID:8516784. |
because mercury decreases dopamine, serotonin, norepinephrine, and acetylcholine in the brain, and nicotine has just the opposite effect on these neurotransmitters, this may help explain why persons with dental amalgams smoke more than persons without amalgams. |
1993-07-19 |
2023-08-12 |
human |
| C Evinger, M A Basso, K A Manning, P A Sibony, J J Pellegrini, A K Hor. A role for the basal ganglia in nicotinic modulation of the blink reflex. Experimental brain research. vol 92. issue 3. 1993-04-21. PMID:8454014. |
three lines of evidence suggest that nicotine affects the blink reflex through the basal ganglia by causing dopamine release in the striatum. |
1993-04-21 |
2023-08-12 |
rat |
| C Evinger, M A Basso, K A Manning, P A Sibony, J J Pellegrini, A K Hor. A role for the basal ganglia in nicotinic modulation of the blink reflex. Experimental brain research. vol 92. issue 3. 1993-04-21. PMID:8454014. |
second, haloperidol, a dopamine (d2) receptor antagonist, blocked the effect of nicotine on the blink reflex. |
1993-04-21 |
2023-08-12 |
rat |
| A M Janson, P B Hedlund, M Hillefors, G von Eule. Chronic nicotine treatment decreases dopamine D2 agonist binding in the rat basal ganglia. Neuroreport. vol 3. issue 12. 1993-03-11. PMID:1362898. |
chronic nicotine treatment decreases dopamine d2 agonist binding in the rat basal ganglia. |
1993-03-11 |
2023-08-11 |
rat |
| A M Janson, P B Hedlund, M Hillefors, G von Eule. Chronic nicotine treatment decreases dopamine D2 agonist binding in the rat basal ganglia. Neuroreport. vol 3. issue 12. 1993-03-11. PMID:1362898. |
to elucidate possible actions of nicotine on dopamine d2 receptor binding, the effect of chronic continuous (-)nicotine treatment (osmotic pumps s.c., 0.125 mg kg h-2, 14 days) was studied in the binding of [3h]n-propylnorapomorphine ([3h]npa) and [125i]sulpride in coronal cryostat sections in the rat. |
1993-03-11 |
2023-08-11 |
rat |
| K P Rajashekhar, J L Wilken. Dopamine and nicotine, but not serotonin, modulate the crustacean ventilatory pattern generator. Journal of neurobiology. vol 23. issue 6. 1992-12-22. PMID:1431839. |
dopamine and nicotine, but not serotonin, modulate the crustacean ventilatory pattern generator. |
1992-12-22 |
2023-08-11 |
Not clear |
| G González Burgos, R E Rosenstein, D P Cardinal. Neurochemical evidence for a neuronal GABAergic system in the rat sympathetic superior cervical ganglion. Journal of neural transmission. General section. vol 89. issue 1-2. 1992-12-04. PMID:1358123. |
none of several putative scg autacoids or agonists (nicotine, muscarine, norepinephrine, dopamine, serotonin, baclofen, muscimol) significantly modified gaba release. |
1992-12-04 |
2023-08-11 |
rat |
| L G Harsing, H Sershen, S E Vizi, A Lajth. N-type calcium channels are involved in the dopamine releasing effect of nicotine. Neurochemical research. vol 17. issue 7. 1992-11-04. PMID:1328912. |
n-type calcium channels are involved in the dopamine releasing effect of nicotine. |
1992-11-04 |
2023-08-11 |
mouse |
| L G Harsing, H Sershen, S E Vizi, A Lajth. N-type calcium channels are involved in the dopamine releasing effect of nicotine. Neurochemical research. vol 17. issue 7. 1992-11-04. PMID:1328912. |
mouse striatum was incubated with [3h]dopamine ([3h]da) and superfused with and the tritium efflux induced by nicotine, electrical stimulation, or simultaneous nicotine and electrical stimulation was measured, to characterize the role of different ca2+ channels in the transmitter release. |
1992-11-04 |
2023-08-11 |
mouse |
| A M Janson, K Fuxe, M Goldstei. Differential effects of acute and chronic nicotine treatment on MPTP-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse. The Clinical investigator. vol 70. issue 3-4. 1992-10-15. PMID:1521037. |
differential effects of acute and chronic nicotine treatment on mptp-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse. |
1992-10-15 |
2023-08-11 |
mouse |
| A M Janson, K Fuxe, M Goldstei. Differential effects of acute and chronic nicotine treatment on MPTP-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse. The Clinical investigator. vol 70. issue 3-4. 1992-10-15. PMID:1521037. |
the present and previous studies indicate that nicotine treatment can markedly alter the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neurotoxicity in the black mouse based on biochemical determinations of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) levels in neostriatum and substantia nigra 2 weeks after mptp injection. |
1992-10-15 |
2023-08-11 |
mouse |
| G W Paulso. Addiction to nicotine is due to high intrinsic levels of dopamine. Medical hypotheses. vol 38. issue 3. 1992-09-25. PMID:1513274. |
addiction to nicotine is due to high intrinsic levels of dopamine. |
1992-09-25 |
2023-08-11 |
Not clear |
| G W Paulso. Addiction to nicotine is due to high intrinsic levels of dopamine. Medical hypotheses. vol 38. issue 3. 1992-09-25. PMID:1513274. |
although nicotine can affect the receptors, including dopamine receptors, it seems unlikely that use of nicotine is protective in pd. |
1992-09-25 |
2023-08-11 |
Not clear |
| G W Paulso. Addiction to nicotine is due to high intrinsic levels of dopamine. Medical hypotheses. vol 38. issue 3. 1992-09-25. PMID:1513274. |
this high innate level of dopamine facilitates addiction to nicotine. |
1992-09-25 |
2023-08-11 |
Not clear |
| J A Rosecran. Nicotine as a discriminative stimulus: a neurobehavioral approach to studying central cholinergic mechanisms. Journal of substance abuse. vol 1. issue 3. 1992-09-24. PMID:2535609. |
finally, these n-ch receptors appear to have a wide distribution and may also sit on presynaptic dopamine neurons, helping to explain some of nicotine's additional behavioral and/or rewarding effects. |
1992-09-24 |
2023-08-11 |
mouse |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
the effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. |
1992-09-22 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
the effects of acute and subchronic nicotine and (+)-amphetamine on the extracellular levels of dopamine and its metabolites, dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in nucleus accumbens (nac) have been studied in conscious, freely-moving rats by use of in vivo microdialysis. |
1992-09-22 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
measurements made 24 h after the last injection of nicotine showed that pretreatment with the higher doses tested (0.4 mg kg-1) resulted in increased basal levels of dopamine (p less than 0.01) and decreased basal levels of dopac (p less than 0.05) in the nac dialysates. |
1992-09-22 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity. British journal of pharmacology. vol 105. issue 4. 1992-09-22. PMID:1504716. |
pretreatment with nicotine (0.1 or 0.4 mg kg-1 daily for 5 days) enhanced the effects of the drug on spontaneous locomotor activity and enhanced the effects of the drug on extracellular levels of dopamine to the extent that the response became significant (p less than 0.05). |
1992-09-22 |
2023-08-11 |
rat |