| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Zhang, M M Meguid, G Miyata, M Varma, S O Fetisso. Role of hypothalamic monoamines in nicotine-induced anorexia in menopausal rats. Surgery. vol 130. issue 2. 2001-09-06. PMID:11490341. |
nicotine and estradiol individually influence hypothalamic dopamine (da) and serotonin (5-ht), whose interaction influences food intake and body weight. |
2001-09-06 |
2023-08-12 |
rat |
| M Reuter, P Nette. The influence of personality on nicotine craving: a hierarchical multivariate statistical prediction model. Neuropsychobiology. vol 44. issue 1. 2001-08-30. PMID:11408793. |
based on animal studies reporting a reduction of the rewarding effects of psychotropic drugs after blockade or destruction of the mesolimbic dopamine (da) system, changes in nicotine craving after pharmacological manipulation by means of a da agonist (lisuride 0.2 mg) and a da antagonist (fluphenazine 2 mg) were assessed in 36 healthy male heavy smokers. |
2001-08-30 |
2023-08-12 |
Not clear |
| P Olausson, P Akesson, J A Engel, B Söderpal. Effects of 5-HT1A and 5-HT2 receptor agonists on the behavioral and neurochemical consequences of repeated nicotine treatment. European journal of pharmacology. vol 420. issue 1. 2001-08-30. PMID:11412838. |
this study investigated the effects of repeated daily (15 days) treatment with nicotine, alone or in combination with the 5-ht1a/7 receptor agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) or the 5-ht2 receptor agonist (+/-)-2,5-dimethoxy-4-iodoamphetamine (doi) on locomotor sensitization, mesolimbic dopamine neurochemistry and on behavioral inhibition in the rat. |
2001-08-30 |
2023-08-12 |
rat |
| P Olausson, P Akesson, J A Engel, B Söderpal. Effects of 5-HT1A and 5-HT2 receptor agonists on the behavioral and neurochemical consequences of repeated nicotine treatment. European journal of pharmacology. vol 420. issue 1. 2001-08-30. PMID:11412838. |
acute nicotine elevated the extracellular dopamine levels in the nucleus accumbens and stimulated locomotor activity, effects that were sensitized after repeated nicotine treatment. |
2001-08-30 |
2023-08-12 |
rat |
| P Olausson, P Akesson, J A Engel, B Söderpal. Effects of 5-HT1A and 5-HT2 receptor agonists on the behavioral and neurochemical consequences of repeated nicotine treatment. European journal of pharmacology. vol 420. issue 1. 2001-08-30. PMID:11412838. |
taken together, these findings suggest that the 5-ht1a and the 5-ht2 receptor subtypes are differentially involved in the effects of repeated nicotine on locomotor sensitization, behavioral inhibition and mesolimbic dopamine neurochemistry. |
2001-08-30 |
2023-08-12 |
rat |
| S M Boye, R J Grant, P B Clark. Disruption of dopaminergic neurotransmission in nucleus accumbens core inhibits the locomotor stimulant effects of nicotine and D-amphetamine in rats. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369033. |
the locomotor stimulant effects of nicotine and amphetamine appear to be dependent on dopamine transmission in the nucleus accumbens. |
2001-08-09 |
2023-08-12 |
rat |
| S M Boye, R J Grant, P B Clark. Disruption of dopaminergic neurotransmission in nucleus accumbens core inhibits the locomotor stimulant effects of nicotine and D-amphetamine in rats. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369033. |
recent evidence suggests that dopamine release in the medial shell may mediate the reinforcing effect of nicotine and d-amphetamine. |
2001-08-09 |
2023-08-12 |
rat |
| S M Boye, R J Grant, P B Clark. Disruption of dopaminergic neurotransmission in nucleus accumbens core inhibits the locomotor stimulant effects of nicotine and D-amphetamine in rats. Neuropharmacology. vol 40. issue 6. 2001-08-09. PMID:11369033. |
in contrast, the present findings suggest that dopamine release in the core subregion contributes preferentially to the locomotor stimulant effects of nicotine and d-amphetamine. |
2001-08-09 |
2023-08-12 |
rat |
| J R Hughe. Why does smoking so often produce dependence? A somewhat different view. Tobacco control. vol 10. issue 1. 2001-07-12. PMID:11226363. |
the usual explanation for why smoking produces dependence focuses on the effects of nicotine on dopamine and other neurobiological explanations. |
2001-07-12 |
2023-08-12 |
Not clear |
| V Zachariou, B J Caldarone, A Weathers-Lowin, T P George, J D Elsworth, R H Roth, J P Changeux, M R Picciott. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 5. 2001-07-12. PMID:11282258. |
the reinforcing properties of nicotine and psychomotor stimulants are thought to be mediated through the mesolimbic dopamine (da) system. |
2001-07-12 |
2023-08-12 |
mouse |
| I Shim, J I Javaid, D Wirtshafter, S Y Jang, K H Shin, H J Lee, Y C Chung, B G Chu. Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat. Behavioural brain research. vol 121. issue 1-2. 2001-06-28. PMID:11275291. |
a direct local challenge of nicotine (1 or 5 mm) via a microdialysis probe in the nucleus accumbens or striatum induced a much greater dose-dependent increase of dopamine (da) output in nicotine-pretreated rats than in saline-pretreated rats. |
2001-06-28 |
2023-08-12 |
rat |
| A E Drew, L L Werlin. Protein kinase C regulation of dopamine transporter initiated by nicotinic receptor activation in slices of rat prefrontal cortex. Journal of neurochemistry. vol 77. issue 3. 2001-06-28. PMID:11331413. |
these findings establish that nicotine can exert selective effects on dopamine transporter activity in prefrontal cortex, an area involved in cognition and learning. |
2001-06-28 |
2023-08-12 |
rat |
| M L Carlsso. On the role of prefrontal cortex glutamate for the antithetical phenomenology of obsessive compulsive disorder and attention deficit hyperactivity disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 1. 2001-06-21. PMID:11263758. |
future pharmacological treatments of these disorders may involve manipulations with glutamate, dopamine d , serotonin 2a and nicotine receptors. |
2001-06-21 |
2023-08-12 |
Not clear |
| J Yeomans, G Forster, C Blah. M5 muscarinic receptors are needed for slow activation of dopamine neurons and for rewarding brain stimulation. Life sciences. vol 68. issue 22-23. 2001-06-21. PMID:11392612. |
nicotinic receptors in vta activate dopamine neurons quickly, and are needed for the stimulant and rewarding effects of nicotine in rats. |
2001-06-21 |
2023-08-12 |
mouse |
| E Carboni, A Silvagni, M T Rolando, G Di Chiar. Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 20. 2001-06-07. PMID:11027253. |
we report that morphine, nicotine, cocaine, ethanol, and the selective dopamine uptake inhibitor gbr 12909 increase effectively and dose dependently extracellular dopamine in the bed nucleus of stria terminalis. |
2001-06-07 |
2023-08-12 |
Not clear |
| J B Becker, C N Rudick, W J Jenkin. The role of dopamine in the nucleus accumbens and striatum during sexual behavior in the female rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312308. |
dopamine in dialysate from the nucleus accumbens (nacc) increases during sexual and feeding behavior and after administration of drugs of abuse, even those that do not directly activate dopaminergic systems (e.g., morphine or nicotine). |
2001-06-07 |
2023-08-12 |
rat |
| M M Meguid, S O Fetissov, M Varma, T Sato, L Zhang, A Laviano, F Rossi-Fanell. Hypothalamic dopamine and serotonin in the regulation of food intake. Nutrition (Burbank, Los Angeles County, Calif.). vol 16. issue 10. 2001-05-31. PMID:11054589. |
nicotine is used as a tool to further explore the relation of meal size to meal number, with a focus on simultaneous changes in dopamine and serotonin concentrations in the lha and vmn with the onset of acute anorexia of nicotine infusion and acute hyperphagia of nicotine cessation. |
2001-05-31 |
2023-08-12 |
Not clear |
| M Fà, G Carcangiu, N Passino, V Ghiglieri, G L Gessa, G Mere. Cigarette smoke inhalation stimulates dopaminergic neurons in rats. Neuroreport. vol 11. issue 16. 2001-05-31. PMID:11095534. |
for this purpose, tobacco smoke from cigarettes containing 1.0 or 0.1 mg nicotine was delivered by inhalation to rats, while recording from antidromically identified nigrostriatal and mesolimbic dopamine neurons. |
2001-05-31 |
2023-08-12 |
rat |
| M Fà, G Carcangiu, N Passino, V Ghiglieri, G L Gessa, G Mere. Cigarette smoke inhalation stimulates dopaminergic neurons in rats. Neuroreport. vol 11. issue 16. 2001-05-31. PMID:11095534. |
smoke inhalation from 1.0 mg nicotine cigarettes caused a peculiar abrupt increase of discharge activity of mesolimbic dopamine neurons, while nigrostriatal cells were less responsive. |
2001-05-31 |
2023-08-12 |
rat |
| M Fà, G Carcangiu, N Passino, V Ghiglieri, G L Gessa, G Mere. Cigarette smoke inhalation stimulates dopaminergic neurons in rats. Neuroreport. vol 11. issue 16. 2001-05-31. PMID:11095534. |
these findings suggest that the boosting activation of mesolimbic dopamine neurons by inhaled nicotine might be relevant for the rewarding properties of tobacco smoking and also for the effectiveness of new treatments to stop smoking. |
2001-05-31 |
2023-08-12 |
rat |