| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
we compared the effects of nicotine and epibatidine on striatal extracellular dopamine and its metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva), by microdialysis in freely moving rats. |
2005-02-14 |
2023-08-12 |
rat |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
nicotine (0.5 mg/kg) elevated dopamine in the caudate-putamen and somewhat more in the nucleus accumbens. |
2005-02-14 |
2023-08-12 |
rat |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
thus, in contrast to nicotine, epibatidine increased dopamine output in the caudate-putamen at smaller doses than in the accumbens. |
2005-02-14 |
2023-08-12 |
rat |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
both epibatidine and nicotine enhanced accumbal dopamine metabolism clearly more than that in the caudate-putamen. |
2005-02-14 |
2023-08-12 |
rat |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
similarly to what has been reported concerning nicotine, the dose-response curve of epibatidine to increase the dopamine output in the caudate-putamen was bell-shaped and clearly differed from that in the accumbens. |
2005-02-14 |
2023-08-12 |
rat |
| Benjamin Boutrel, George F Koo. What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications. Sleep. vol 27. issue 6. 2005-02-08. PMID:15532213. |
nicotine enhances acetylcholine neurotransmission in the basal forebrain and dopamine release. |
2005-02-08 |
2023-08-12 |
Not clear |
| Michael N Smolka, Henning Budde, Anne C Karow, Lutz G Schmid. Neuroendocrinological and neuropsychological correlates of dopaminergic function in nicotine dependence. Psychopharmacology. vol 175. issue 3. 2005-02-02. PMID:15114432. |
there is multiple evidence that nicotine--as with ethanol and other drugs of abuse--stimulates dopamine release in the ventral striatum as a central part of the brain reward circuits. |
2005-02-02 |
2023-08-12 |
Not clear |
| Steven B Harrod, Charles F Mactutus, Klark Bennett, Ulla Hasselrot, Guanghan Wu, Marion Welch, Rosemarie M Booz. Sex differences and repeated intravenous nicotine: behavioral sensitization and dopamine receptors. Pharmacology, biochemistry, and behavior. vol 78. issue 3. 2005-01-26. PMID:15251267. |
sex differences and repeated intravenous nicotine: behavioral sensitization and dopamine receptors. |
2005-01-26 |
2023-08-12 |
rat |
| Steven B Harrod, Charles F Mactutus, Klark Bennett, Ulla Hasselrot, Guanghan Wu, Marion Welch, Rosemarie M Booz. Sex differences and repeated intravenous nicotine: behavioral sensitization and dopamine receptors. Pharmacology, biochemistry, and behavior. vol 78. issue 3. 2005-01-26. PMID:15251267. |
the present study examined the sex-dependent expression of behavioral sensitization as well as changes of dopamine (da) transporters and d1, d2, and d3 receptors following repeated intravenous nicotine administration. |
2005-01-26 |
2023-08-12 |
rat |
| Alexander R Kosowski, Sture Liljequis. The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(+/-)-(R*,S*)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 311. issue 2. 2005-01-25. PMID:15256539. |
the nr2b-selective n-methyl-d-aspartate receptor antagonist ro 25-6981 [(+/-)-(r*,s*)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nucleus accumbens. |
2005-01-25 |
2023-08-12 |
rat |
| Shafiqur Rahman, Jianhua Zhang, William A Corrigal. Effects of nicotine preexposure on sulpiride-induced dopamine release in the nucleus accumbens. European journal of pharmacology. vol 494. issue 1. 2005-01-13. PMID:15194448. |
effects of nicotine preexposure on sulpiride-induced dopamine release in the nucleus accumbens. |
2005-01-13 |
2023-08-12 |
rat |
| Shafiqur Rahman, Jianhua Zhang, William A Corrigal. Effects of nicotine preexposure on sulpiride-induced dopamine release in the nucleus accumbens. European journal of pharmacology. vol 494. issue 1. 2005-01-13. PMID:15194448. |
we examined the effects of nicotine preexposure or saline on dopamine release to sulpiride in the rat nucleus accumbens. |
2005-01-13 |
2023-08-12 |
rat |
| Shafiqur Rahman, Jianhua Zhang, William A Corrigal. Effects of nicotine preexposure on sulpiride-induced dopamine release in the nucleus accumbens. European journal of pharmacology. vol 494. issue 1. 2005-01-13. PMID:15194448. |
the reduction of sulpiride-induced nucleus accumbens dopamine release after nicotine treatment is likely the result of down-regulation of somatodendritic dopamine autoreceptors. |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
thus, a quantitative microdialysis (no-net-flux) approach was used to measure basal extracellular concentrations and extraction fractions of dopamine in the nucleus accumbens (acb) of rats that self-administered nicotine i.v. |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
the basal extracellular dopamine levels in the yoked nicotine group (1.46+/-0.20 nm) were not significantly different compared with the nicotine self-administration group. |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
the in vivo extraction fraction of dopamine, an indirect measure of dopamine uptake, was significantly increased in the nicotine self-administration (86%) and yoked nicotine (91%) groups compared with the yoked saline group (77%). |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
in addition, a marked reduction in the elevation of extracellular dopamine levels in the acb occurred after a nicotine challenge as measured by conventional microdialysis in the self-administration (112% of basal) and yoked nicotine (121% of basal) groups as compared with a yoked saline (154% of basal) group. |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
the reduced basal acb dopamine levels in the nicotine groups during early abstinence appears to be due to increased clearance, suggesting increased dopamine uptake is occurring as a result of the chronic nicotine treatment. |
2005-01-13 |
2023-08-12 |
rat |
| S Rahman, J Zhang, E A Engleman, W A Corrigal. Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study. Neuroscience. vol 129. issue 2. 2005-01-13. PMID:15501598. |
the reduced elevation of extracellular dopamine levels in the acb upon nicotine challenge suggests a functional desensitization or downregulation phenomenon involving acetylcholine receptors (nicotinic nachrs). |
2005-01-13 |
2023-08-12 |
rat |
| Eduardo J B Ramos, Michael M Meguid, Lihua Zhang, Go Miyata, Serguei O Fetissov, Chung Chen, Susumu Suzuki, Alessandro Lavian. Nicotine infusion into rat ventromedial nuclei and effects on monoaminergic system. Neuroreport. vol 15. issue 14. 2005-01-11. PMID:15371752. |
we hypothesize that nicotine influences fi via alteration of serotonin (5ht) and dopamine (da) concentration in ventromedial nucleus (vmn) and lateral hypothalamic area (lha). |
2005-01-11 |
2023-08-12 |
rat |