| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Zhang, David Sulze. Frequency-dependent modulation of dopamine release by nicotine. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146187. |
nicotine may thus enhance the contrast of dopamine signals associated with behavioral cues. |
2004-07-20 |
2023-08-12 |
Not clear |
| Margaret E Rice, Stephanie J Crag. Nicotine amplifies reward-related dopamine signals in striatum. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146188. |
nicotine amplifies reward-related dopamine signals in striatum. |
2004-07-20 |
2023-08-12 |
Not clear |
| Margaret E Rice, Stephanie J Crag. Nicotine amplifies reward-related dopamine signals in striatum. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146188. |
using guinea pig brain slices, we show that nicotine, like cocaine and amphetamine, acts directly in striatum where it enhances dopamine release during phasic but not tonic activity. |
2004-07-20 |
2023-08-12 |
Not clear |
| Margaret E Rice, Stephanie J Crag. Nicotine amplifies reward-related dopamine signals in striatum. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146188. |
this amplification provides a mechanism for nicotine facilitation of reward-related dopamine signals, including responses to other primary reinforcers that govern nicotine dependence in smokers. |
2004-07-20 |
2023-08-12 |
Not clear |
| Peter P Rowell, Kelly A Vol. Nicotinic activation of mesolimbic neurons assessed by rubidium efflux in rat accumbens and ventral tegmentum. Neuro-Signals. vol 13. issue 3. 2004-07-06. PMID:15067198. |
the application of nicotine to either the vta or nac produces an increase in dopamine release; however, the positive reinforcement produced by the systemic injection of nicotine is primarily due to stimulation of nicotinic acetylcholine receptors (nachrs) in the vta. |
2004-07-06 |
2023-08-12 |
rat |
| Shupeng Li, Kun Yang Kim, Jong Hun Kim, Jin Hoi Kim, Moon Seok Park, Jong Yoon Bahk, Myeong Ok Ki. Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain. Neuroscience letters. vol 363. issue 1. 2004-07-06. PMID:15157990. |
chronic nicotine and smoking treatment increases dopamine transporter mrna expression in the rat midbrain. |
2004-07-06 |
2023-08-12 |
rat |
| Shupeng Li, Kun Yang Kim, Jong Hun Kim, Jin Hoi Kim, Moon Seok Park, Jong Yoon Bahk, Myeong Ok Ki. Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain. Neuroscience letters. vol 363. issue 1. 2004-07-06. PMID:15157990. |
previous pharmacokinetics and electrophysiological results indicated an important role of nicotine in the modulation of dopamine transporter (dat). |
2004-07-06 |
2023-08-12 |
rat |
| Douglas P Dohrman And, Cindy K Reite. Chronic ethanol reduces nicotine-induced dopamine release in PC12 cells. Alcoholism, clinical and experimental research. vol 27. issue 11. 2004-06-29. PMID:14634503. |
the release of dopamine from these neurons is thought to mediate, at least in part, the reward of nicotine consumption. |
2004-06-29 |
2023-08-12 |
Not clear |
| Douglas P Dohrman And, Cindy K Reite. Chronic ethanol reduces nicotine-induced dopamine release in PC12 cells. Alcoholism, clinical and experimental research. vol 27. issue 11. 2004-06-29. PMID:14634503. |
if chronic alcohol consumption affects the amount of dopamine released in response to nicotine, it could contribute to the high level of smoking seen in alcoholics. |
2004-06-29 |
2023-08-12 |
Not clear |
| Hiroaki Matsubayashi, Taku Amano, Takahiro Seki, Masashi Sasa, Norio Saka. Electrophysiological characterization of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578581. |
nicotine directly acts on postsynaptic alpha4beta2 type nicotinic receptors and induces inward currents, resulting in excitation of dopaminergic neurons in the substantia nigra and subsequent enhancement of dopamine release in the corpus striatum. |
2004-06-18 |
2023-08-12 |
rat |
| Anne-Sophie Villégier, Gérard Blanc, Jacques Glowinski, Jean-Pol Tassi. Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors. Pharmacology, biochemistry, and behavior. vol 76. issue 2. 2004-06-18. PMID:14592678. |
drugs of abuse, such as d-amphetamine or nicotine, are generally considered as acting through an increased release of dopamine in a subcortical structure, the nucleus accumbens, thus inducing locomotor hyperactivity in rats. |
2004-06-18 |
2023-08-12 |
rat |
| Rafael J Salín-Pascual, Natasha V Alcocer-Castillejos, Gabriel Alejo-Galarz. Nicotine dependence and psychiatric disorders. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. vol 55. issue 6. 2004-06-01. PMID:15011738. |
nicotine receptors in cns are located mainly in presynaptic membrane and in that way they regulated the release of several neurotransmitters, among them acetylcholine, dopamine, serotonin, and norepinephrine. |
2004-06-01 |
2023-08-12 |
rat |
| Michael C Lewis, Thomas J Goul. Nicotine and ethanol enhancements of acoustic startle reflex are mediated in part by dopamine in C57BL/6J mice. Pharmacology, biochemistry, and behavior. vol 76. issue 1. 2004-05-10. PMID:13679231. |
nicotine and ethanol enhancements of acoustic startle reflex are mediated in part by dopamine in c57bl/6j mice. |
2004-05-10 |
2023-08-12 |
mouse |
| Michael C Lewis, Thomas J Goul. Nicotine and ethanol enhancements of acoustic startle reflex are mediated in part by dopamine in C57BL/6J mice. Pharmacology, biochemistry, and behavior. vol 76. issue 1. 2004-05-10. PMID:13679231. |
haloperidol (1 mg/kg) was administered in combination with nicotine or ethanol to investigate if dopamine modulated nicotine or ethanol enhancement of acoustic startle. |
2004-05-10 |
2023-08-12 |
mouse |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin-mediated model for trisomy 21. Pediatric pathology & molecular medicine. vol 22. issue 5. 2004-05-06. PMID:14692193. |
there were increased levels of tryptophan catabolites--nicotine, strychnine, quinolinic acid, and serotonin--and decreased levels of tyrosine catabolites--dopamine, noradrenaline, and morphine in trisomy 21. |
2004-05-06 |
2023-08-12 |
Not clear |
| Massimo Pierucci, Vincenzo Di Matteo, Ennio Esposit. Stimulation of serotonin2C receptors blocks the hyperactivation of midbrain dopamine neurons induced by nicotine administration. The Journal of pharmacology and experimental therapeutics. vol 309. issue 1. 2004-05-04. PMID:14722316. |
stimulation of serotonin2c receptors blocks the hyperactivation of midbrain dopamine neurons induced by nicotine administration. |
2004-05-04 |
2023-08-12 |
rat |
| Massimo Pierucci, Vincenzo Di Matteo, Ennio Esposit. Stimulation of serotonin2C receptors blocks the hyperactivation of midbrain dopamine neurons induced by nicotine administration. The Journal of pharmacology and experimental therapeutics. vol 309. issue 1. 2004-05-04. PMID:14722316. |
in vivo electrophysiological techniques were used to study the effect of nicotine on the basal activity of dopamine (da)-containing neurons in the substantia nigra pars compacta (snc) and the ventral tegmental area (vta) of chloral hydrate-anesthetized rats. |
2004-05-04 |
2023-08-12 |
rat |
| Vincenzo Di Matteo, Massimo Pierucci, Ennio Esposit. Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration. Journal of neurochemistry. vol 89. issue 2. 2004-05-04. PMID:15056285. |
selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration. |
2004-05-04 |
2023-08-12 |
rat |
| Vincenzo Di Matteo, Massimo Pierucci, Ennio Esposit. Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration. Journal of neurochemistry. vol 89. issue 2. 2004-05-04. PMID:15056285. |
the effects of acute and repeated nicotine administration on the extracellular levels of dopamine (da) in the corpus striatum and the nucleus accumbens were studied in conscious, freely moving rats by in vivo microdialysis. |
2004-05-04 |
2023-08-12 |
rat |
| Volodymyr I Pidoplichko, Jun Noguchi, Oluwasanmi O Areola, Yong Liang, Jayms Peterson, Tianxiang Zhang, John A Dan. Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 1. 2004-04-30. PMID:14747518. |
here we show that nicotine, in the same concentration and time ranges as obtained from tobacco, has three main actions that regulate the activity of midbrain dopamine (da) neurons. |
2004-04-30 |
2023-08-12 |
Not clear |