| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin, hemispheric chemical dominance, and eating behavior. The International journal of neuroscience. vol 113. issue 8. 2003-10-17. PMID:12888426. |
the serum hmg coa reductase activity, rbc membrane na+-k+ atpase activity, serum digoxin, magnesium, tryptophan catabolites (serotonin, quinolinic acid, strychnine, and nicotine), and tyrosine catabolites (morphine, dopamine, and noradrenaline) were measured in anorexia nervosa, bulimia nervosa, right hemispheric dominant, left hemispheric dominant, and bihemispheric dominant individuals. |
2003-10-17 |
2023-08-12 |
Not clear |
| Vladimir P Grinevich, Peter A Crooks, Sangeetha P Sumithran, Aaron J Haubner, Joshua T Ayers, Linda P Dwoski. N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices. The Journal of pharmacology and experimental therapeutics. vol 306. issue 3. 2003-10-03. PMID:12766255. |
n-n-alkylpyridinium analog inhibition of [3h]nicotine and [3h]methyllycaconitine binding to rat brain membranes assessed interaction with alpha4beta2* and alpha7* nachrs, respectively, whereas inhibition of nicotine-evoked 3h overflow from [3h]dopamine ([3h]da)-preloaded rat striatal slices assessed antagonist action at nachr subtypes mediating nicotine-evoked da release. |
2003-10-03 |
2023-08-12 |
rat |
| Kouichi Yoshimasu, Chikako Kiyohar. Genetic influences on smoking behavior and nicotine dependence: a review. Journal of epidemiology. vol 13. issue 4. 2003-10-02. PMID:12934961. |
dopamine receptor genes, transporter genes (serotonin and dopamine), and other genes related to metabolism of nicotine are plausible functional candidate genes. |
2003-10-02 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin--central role in conscious perception, neuroimmunoendocrine integration and coordination of cellular function--relation to hemispheric dominance. Medical hypotheses. vol 60. issue 2. 2003-09-26. PMID:12606243. |
digoxin can also preferentially upregulate tryptophan transport over tyrosine resulting in increased levels of depolarising tryptophan catabolites - serotonin, quinolinic acid, strychnine and nicotine and decreased levels of hyperpolarising tyrosine catabolites dopamine, noradrenaline and morphine contributing to membrane na(+)-k(+) atpase inhibition in all the above disorders and the indexed family. |
2003-09-26 |
2023-08-12 |
Not clear |
| S Rahman, J Zhang, W A Corrigal. Effects of acute and chronic nicotine on somatodendritic dopamine release of the rat ventral tegmental area: in vivo microdialysis study. Neuroscience letters. vol 348. issue 2. 2003-09-26. PMID:12902018. |
effects of acute and chronic nicotine on somatodendritic dopamine release of the rat ventral tegmental area: in vivo microdialysis study. |
2003-09-26 |
2023-08-12 |
rat |
| S Rahman, J Zhang, W A Corrigal. Effects of acute and chronic nicotine on somatodendritic dopamine release of the rat ventral tegmental area: in vivo microdialysis study. Neuroscience letters. vol 348. issue 2. 2003-09-26. PMID:12902018. |
the objectives of the present study were to examine the effects of acute and chronic nicotine on dopamine (da) release in the ventral tegmental area (vta) of long-evans rats using in vivo microdialysis. |
2003-09-26 |
2023-08-12 |
rat |
| Neil E Paterson, Svetlana Semenova, Fabrizio Gasparini, Athina Marko. The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology. vol 167. issue 3. 2003-09-24. PMID:12682710. |
nicotine increases glutamate release in the ventral tegmental area and the nucleus accumbens, and thus enhances dopamine neurotransmission in the mesolimbic system that has been implicated in mediating the rewarding effects of drugs. |
2003-09-24 |
2023-08-12 |
mouse |
| B Le Foll, J-C Schwartz, P Sokolof. Disruption of nicotine conditioning by dopamine D(3) receptor ligands. Molecular psychiatry. vol 8. issue 2. 2003-09-23. PMID:12610655. |
disruption of nicotine conditioning by dopamine d(3) receptor ligands. |
2003-09-23 |
2023-08-12 |
rat |
| B Le Foll, J-C Schwartz, P Sokolof. Disruption of nicotine conditioning by dopamine D(3) receptor ligands. Molecular psychiatry. vol 8. issue 2. 2003-09-23. PMID:12610655. |
nicotine, like other drugs of abuse, activates the dopamine mesolimbic system, which originates in the ventral tegmental area and projects notably to the nucleus accumbens. |
2003-09-23 |
2023-08-12 |
rat |
| Robyn Richmond, Nicholas Zwa. Review of bupropion for smoking cessation. Drug and alcohol review. vol 22. issue 2. 2003-09-17. PMID:12850907. |
bupropion is a selective re-uptake inhibitor of dopamine and noradrenalin which prevents or reduces cravings and other features of nicotine withdrawal. |
2003-09-17 |
2023-08-12 |
human |
| Paul Cumming, Pedro Rosa-Neto, Hideaki Watanabe, Donald Smith, Dirk Bender, Paul B S Clarke, Albert Gjedd. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. NeuroImage. vol 19. issue 3. 2003-09-09. PMID:12880838. |
effects of acute nicotine on hemodynamics and binding of [11c]raclopride to dopamine d2,3 receptors in pig brain. |
2003-09-09 |
2023-08-12 |
Not clear |
| Paul Cumming, Pedro Rosa-Neto, Hideaki Watanabe, Donald Smith, Dirk Bender, Paul B S Clarke, Albert Gjedd. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. NeuroImage. vol 19. issue 3. 2003-09-09. PMID:12880838. |
positive reinforcing properties of nicotine and the psychostimulants have been attributed to elevated dopamine release in the basal ganglia. |
2003-09-09 |
2023-08-12 |
Not clear |
| Paul Cumming, Pedro Rosa-Neto, Hideaki Watanabe, Donald Smith, Dirk Bender, Paul B S Clarke, Albert Gjedd. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. NeuroImage. vol 19. issue 3. 2003-09-09. PMID:12880838. |
evidently, nicotine challenge enhances the competition between endogenous dopamine for [(11)c]raclopride binding sites with a complex temporal and spacial pattern in pig brain, initially presenting in the left ventral striatum. |
2003-09-09 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Endogenous digoxin, hemispheric dominance and family bonding behavior. Neurological research. vol 25. issue 4. 2003-09-04. PMID:12870268. |
digoxin synthesis was increased with upregulated tryptophan catabolism (increased levels of serotonin, strychnine and nicotine) and down regulated tyrosine catabolism (decreased levels of dopamine, noradrenaline and morphine) in those with reduced family bonding and right hemispheric chemical dominance. |
2003-09-04 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Endogenous digoxin, hemispheric dominance and family bonding behavior. Neurological research. vol 25. issue 4. 2003-09-04. PMID:12870268. |
digoxin synthesis was reduced with down regulated tryptophan catabolism (decreased levels of serotonin, strychnine and nicotine) and upregulated tyrosine catabolism (increased levels of dopamine, noradrenaline and morphine) in those with increased family bonding and left hemispheric chemical dominance. |
2003-09-04 |
2023-08-12 |
Not clear |
| Michela Andreoli, Michela Tessari, Maria Pilla, Enzo Valerio, Jim J Hagan, Christian A Heidbrede. Selective antagonism at dopamine D3 receptors prevents nicotine-triggered relapse to nicotine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12700694. |
drugs of abuse, including, nicotine have been shown to enhance brain reward functions in the mesocortico-limbic dopamine (da) system in general, and the nucleus accumbens in particular. |
2003-09-02 |
2023-08-12 |
rat |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin-mediated model for Parkinson's disease. The International journal of neuroscience. vol 113. issue 4. 2003-08-29. PMID:12856480. |
serum tryptophan, serotonin, strychnine, nicotine, and quinolinic acid were elevated, while tyrosine, morphine, dopamine, and noradrenaline were decreased. |
2003-08-29 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin, hemispheric chemical dominance, and sleep. The International journal of neuroscience. vol 113. issue 4. 2003-08-29. PMID:12856481. |
digoxin synthesis was increased with upregulated tryptophan catabolism (increased levels of serotonin, strychnine, and nicotine), and downregulated tyrosine catabolism (decreased levels of dopamine, noradrenaline, and morphine) in those with chronic insomnia and right hemispheric chemical dominance. |
2003-08-29 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin, hemispheric chemical dominance, and sleep. The International journal of neuroscience. vol 113. issue 4. 2003-08-29. PMID:12856481. |
digoxin synthesis was reduced with downregulated tryptophan catabolism (decreased levels of serotonin, strychnine, and nicotine) and upregulated tyrosine catabolism (increased levels of dopamine, noradrenaline, and morphine) in those with normal sleep patterns and left hemispheric chemical dominance. |
2003-08-29 |
2023-08-12 |
Not clear |
| Ravi Kumar Kurup, Parameswara Achutha Kuru. Hypothalamic digoxin, hemispheric chemical dominance, and creativity. The International journal of neuroscience. vol 113. issue 4. 2003-08-29. PMID:12856483. |
in creative individuals there was increased digoxin synthesis, decreased membrane na(+)-k+ atpase activity, increased tryptophan catabolites (serotonin, quinolinic acid, and nicotine), and decreased tyrosine catabolites (dopamine, noradrenaline, and morphine). |
2003-08-29 |
2023-08-12 |
human |