| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vasile Hefco, Kiyofumi Yamada, Andreea Hefco, Lucian Hritcu, Adrian Tiron, Ana Olariu, Toshitaka Nabeshim. Effects of nicotine on memory impairment induced by blockade of muscarinic, nicotinic and dopamine D2 receptors in rats. European journal of pharmacology. vol 474. issue 2-3. 2004-04-23. PMID:12921867. |
effects of nicotine on memory impairment induced by blockade of muscarinic, nicotinic and dopamine d2 receptors in rats. |
2004-04-23 |
2023-08-12 |
rat |
| Vasile Hefco, Kiyofumi Yamada, Andreea Hefco, Lucian Hritcu, Adrian Tiron, Ana Olariu, Toshitaka Nabeshim. Effects of nicotine on memory impairment induced by blockade of muscarinic, nicotinic and dopamine D2 receptors in rats. European journal of pharmacology. vol 474. issue 2-3. 2004-04-23. PMID:12921867. |
nicotine, by activating the nicotinic acetylcholine receptors, attenuated the impairment of short-term memory induced by muscarinic or dopamine d2 receptor blockade. |
2004-04-23 |
2023-08-12 |
rat |
| Sean P David, Raymond Niaura, George D Papandonatos, William G Shadel, Gary J Burkholder, Dana M Britt, Amy Day, Jeffrey Stumpff, Kent Hutchison, Michael Murphy, Elaine Johnstone, Siân-Elin Griffiths, Robert T Walto. Does the DRD2-Taq1 A polymorphism influence treatment response to bupropion hydrochloride for reduction of the nicotine withdrawal syndrome? Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 5. issue 6. 2004-04-22. PMID:14668077. |
bupropion is a weak dopamine reuptake inhibitor, and individual genetic variation in the dopamine d2 receptor has been associated with nicotine dependence in case-control studies. |
2004-04-22 |
2023-08-12 |
human |
| Sean P David, Raymond Niaura, George D Papandonatos, William G Shadel, Gary J Burkholder, Dana M Britt, Amy Day, Jeffrey Stumpff, Kent Hutchison, Michael Murphy, Elaine Johnstone, Siân-Elin Griffiths, Robert T Walto. Does the DRD2-Taq1 A polymorphism influence treatment response to bupropion hydrochloride for reduction of the nicotine withdrawal syndrome? Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 5. issue 6. 2004-04-22. PMID:14668077. |
these data suggest that bupropion attenuates specific symptoms of the nicotine withdrawal syndrome and that this effect may be modified by genotype for the dopamine d2 receptor. |
2004-04-22 |
2023-08-12 |
human |
| Christina Gianoulaki. Endogenous opioids and addiction to alcohol and other drugs of abuse. Current topics in medicinal chemistry. vol 4. issue 1. 2004-04-21. PMID:14754375. |
it has also been shown that regardless of their initial site of action many drugs of abuse, such as morphine, nicotine, cocaine, alcohol and amphetamines, induce an increase in the extracellular concentration of dopamine in the nucleus accumbens. |
2004-04-21 |
2023-08-12 |
Not clear |
| Allison E Drew, Linda L Werlin. Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine. Schizophrenia research. vol 65. issue 1. 2004-04-06. PMID:14623374. |
nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine. |
2004-04-06 |
2023-08-12 |
rat |
| Ravi kumar Kurup, Rekha A Nair, Parameswara Achutha Kuru. Isoprenoid pathway related cascade in multiple myeloma. Pathology oncology research : POR. vol 9. issue 2. 2004-04-01. PMID:12858216. |
serum tryptophan, serotonin, nicotine, strychnine and quinolinic acid were elevated while tyrosine, dopamine, noradrenaline and morphine were decreased. |
2004-04-01 |
2023-08-12 |
Not clear |
| Daijun Ling, Tianhua Niu, Yan Feng, Houxun Xing, Xiping X. Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence. Journal of human genetics. vol 49. issue 1. 2004-03-24. PMID:14685824. |
association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence. |
2004-03-24 |
2023-08-12 |
Not clear |
| Daijun Ling, Tianhua Niu, Yan Feng, Houxun Xing, Xiping X. Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence. Journal of human genetics. vol 49. issue 1. 2004-03-24. PMID:14685824. |
previous studies suggested that a polymorphism in the dopamine transporter gene (slc6a3) is associated with nicotine dependence and age of smoking onset, but the conclusion was controversial. |
2004-03-24 |
2023-08-12 |
Not clear |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent lewis rats. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
the effects of chronic gestational exposure to nicotine on the nucleus accumbens dopamine response to acute nicotine were determined during adolescence (postnatal day 29-36) in cross-fostered and noncross-fostered lewis rats. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
in both males and females, gestational nicotine exposure diminished the adolescent nucleus accumbens dopamine response to 0.07 mg/kg nicotine i.v. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
however, dopamine responses to 0.105 mg/kg nicotine were unaffected by gestational nicotine treatment and were similar in both genders. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
furthermore, in both female and male gestational nicotine and control groups, the dopamine response to nicotine (0.105) was the same as that observed to the lower dose of nicotine in gestational controls. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
thus, in adolescent male and female lewis rats, gestational nicotine exposure attenuated nucleus accumbens dopamine release to a maximally stimulative dose of nicotine. |
2004-03-11 |
2023-08-12 |
rat |
| Victoria B Kane, Yitong Fu, Shannon G Matta, Burt M Shar. Gestational nicotine exposure attenuates nicotine-stimulated dopamine release in the nucleus accumbens shell of adolescent Lewis rats. The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610222. |
unexpectedly, in female gestational controls cross-fostering per se reduced nucleus accumbens dopamine secretion to 0.07 mg/kg nicotine (p < 0.05). |
2004-03-11 |
2023-08-12 |
rat |
| Tony P George, Stephanie S O'Malle. Current pharmacological treatments for nicotine dependence. Trends in pharmacological sciences. vol 25. issue 1. 2004-02-17. PMID:14723978. |
recent developments in our understanding of the neurobiology of nicotine dependence have identified several neurotransmitter systems that might contribute to the process of smoking maintenance and relapse, including dopamine, noradrenaline, 5-hydroxytryptamine, acetylcholine, endogenous opioids, gaba, glutamate and endocannabinoids. |
2004-02-17 |
2023-08-12 |
Not clear |
| Lisa S Middleton, Wayne A Cass, Linda P Dwoski. Nicotinic receptor modulation of dopamine transporter function in rat striatum and medial prefrontal cortex. The Journal of pharmacology and experimental therapeutics. vol 308. issue 1. 2004-02-11. PMID:14563785. |
nicotine activates nicotinic acetylcholine receptors (nachrs) on dopamine (da) terminals to evoke da release, which subsequently is taken back up into the terminal via the da transporter (dat). |
2004-02-11 |
2023-08-12 |
rat |
| Caryn Lerman, Peter G Shields, E Paul Wileyto, Janet Audrain, Larry H Hawk, Angela Pinto, Susan Kucharski, Shiva Krishnan, Ray Niaura, Leonard H Epstei. Effects of dopamine transporter and receptor polymorphisms on smoking cessation in a bupropion clinical trial. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 22. issue 5. 2004-02-09. PMID:14570538. |
assessments included the dopamine d2 receptor (drd2) genotype, dopamine transporter (slc6a3) genotype, demographic factors, and nicotine dependence. |
2004-02-09 |
2023-08-12 |
Not clear |
| Francesca Risso, Monica Parodi, Massimo Grilli, Francesca Molfino, Maurizio Raiteri, Mario March. Chronic nicotine causes functional upregulation of ionotropic glutamate receptors mediating hippocampal noradrenaline and striatal dopamine release. Neurochemistry international. vol 44. issue 5. 2004-02-02. PMID:14643746. |
chronic nicotine causes functional upregulation of ionotropic glutamate receptors mediating hippocampal noradrenaline and striatal dopamine release. |
2004-02-02 |
2023-08-12 |
rat |