| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhong-Hua Liu, Wen-Qiao Ji. Decrease of ventral tegmental area dopamine neuronal activity in nicotine withdrawal rats. Neuroreport. vol 15. issue 9. 2004-09-16. PMID:15194878. |
the results indicate that the vta dopamine neuronal activity is reduced during the first day of nicotine withdrawal. |
2004-09-16 |
2023-08-12 |
rat |
| Kimberly A Badanich, Cheryl L Kirstein. Nicotine administration significantly alters accumbal dopamine in the adult but not in the adolescent rat. Annals of the New York Academy of Sciences. vol 1021. 2004-08-23. PMID:15251919. |
nicotine administration significantly alters accumbal dopamine in the adult but not in the adolescent rat. |
2004-08-23 |
2023-08-12 |
rat |
| Mohammed Shoaib, Andrew S Lowe, Steve C R William. Imaging localised dynamic changes in the nucleus accumbens following nicotine withdrawal in rats. NeuroImage. vol 22. issue 2. 2004-08-19. PMID:15193614. |
these findings are consistent with previous neurochemical reports on decreases in dopamine in the nac during nicotine withdrawal. |
2004-08-19 |
2023-08-12 |
rat |
| Arthur L Brody, Richard E Olmstead, Edythe D London, Judah Farahi, Jeffrey H Meyer, Paul Grossman, Grace S Lee, Joe Huang, Emily L Hahn, Mark A Mandelker. Smoking-induced ventral striatum dopamine release. The American journal of psychiatry. vol 161. issue 7. 2004-08-19. PMID:15229053. |
substantial evidence from animal models demonstrates that dopamine release in the ventral striatum underlies the reinforcing properties of nicotine. |
2004-08-19 |
2023-08-12 |
Not clear |
| David Gilbert, Joseph McClernon, Norka Rabinovich, Chihiro Sugai, Louisette Plath, Greg Asgaard, Yantao Zuo, Jodi Huggenvik, Nazeih Botro. Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 6. issue 2. 2004-08-18. PMID:15203798. |
individuals high in trait depression or nicotine dependence or with at least one dopamine d(2) receptor a1 allele experienced greater eeg deactivation following abstinence, especially in the right hemisphere during the stressful task. |
2004-08-18 |
2023-08-12 |
Not clear |
| Anna Molander, Bo Söderpal. Pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. European journal of pharmacology. vol 481. issue 1. 2004-08-12. PMID:14637174. |
pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. |
2004-08-12 |
2023-08-12 |
rat |
| Anna Molander, Bo Söderpal. Pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. European journal of pharmacology. vol 481. issue 1. 2004-08-12. PMID:14637174. |
the reinforcing properties of nicotine may be related to its ability to release dopamine in the nucleus accumbens and to increase locomotor activity in experimental animals. |
2004-08-12 |
2023-08-12 |
rat |
| Anna Molander, Bo Söderpal. Pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. European journal of pharmacology. vol 481. issue 1. 2004-08-12. PMID:14637174. |
adrenalectomy or sham-operated rats received daily nicotine (0.4 mg/kg s.c.) or vehicle for 15 days, after which the locomotor responses to nicotine (0.2 mg/kg s.c.) and the dopamine d1/d2 receptor agonist apomorphine (1.0 mg/kg s.c. or 100 microm in the nucleus accumbens by reversed microdialysis) were recorded. |
2004-08-12 |
2023-08-12 |
rat |
| Anna Molander, Bo Söderpal. Pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. European journal of pharmacology. vol 481. issue 1. 2004-08-12. PMID:14637174. |
in addition, accumbal dopamine output was monitored by in vivo microdialysis after nicotine challenge. |
2004-08-12 |
2023-08-12 |
rat |
| Anna Molander, Bo Söderpal. Pre- and postsynaptic dopamine mechanisms after repeated nicotine: effects of adrenalectomy. European journal of pharmacology. vol 481. issue 1. 2004-08-12. PMID:14637174. |
nicotine increased accumbal dopamine output in all animals. |
2004-08-12 |
2023-08-12 |
rat |
| B Schilström, M Mameli-Engvall, N Rawal, P Grillner, K Jardemark, T H Svensso. Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons. Neuroscience. vol 125. issue 4. 2004-08-02. PMID:15120855. |
in the present study, using single cell recordings in vivo and intracellular recordings in vitro from midbrain slices, the role of n-methyl-d-aspartate (nmda) receptor signaling on firing activity in ventral tegmental area dopamine neurons elicited by nicotine was investigated in the rat. |
2004-08-02 |
2023-08-12 |
rat |
| B Schilström, M Mameli-Engvall, N Rawal, P Grillner, K Jardemark, T H Svensso. Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons. Neuroscience. vol 125. issue 4. 2004-08-02. PMID:15120855. |
in accordance with previous studies, systemic nicotine (0.5 mg/kg s.c.) increased both firing rate and burst firing of dopamine neurons in vivo, and bath-applied nicotine (10 microm) increased firing rate in vitro. |
2004-08-02 |
2023-08-12 |
rat |
| B Schilström, M Mameli-Engvall, N Rawal, P Grillner, K Jardemark, T H Svensso. Nitric oxide is involved in nicotine-induced burst firing of rat ventral tegmental area dopamine neurons. Neuroscience. vol 125. issue 4. 2004-08-02. PMID:15120855. |
in contrast, l-name (100 microm) did not influence nicotine's effect on dopamine cell firing in vitro, suggesting that the effect of l-name seen in vivo is dependent on presynaptic afferent input. |
2004-08-02 |
2023-08-12 |
rat |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
upstream of the dopaminergic neurons nicotine induces long-term potentiation of the excitatory input to dopamine cells in the ventral tegmental area, and depresses inhibitory inputs. |
2004-07-22 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
however, downstream of dopamine, effects of nicotine are also likely to occur. |
2004-07-22 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, Mischa De Rover, Daniel S McGehee, Arjen B Brussaar. Cholinergic modulation of dopaminergic reward areas: upstream and downstream targets of nicotine addiction. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623355. |
thus, synaptic mechanisms both upstream and downstream of dopamine release are potentially important factors contributing to the etiology of nicotine addiction. |
2004-07-22 |
2023-08-12 |
Not clear |
| S Silvestri, J C Negrete, M V Seeman, C M Shammi, P Seema. Does nicotine affect D2 receptor upregulation? A case-control study. Acta psychiatrica Scandinavica. vol 109. issue 4. 2004-07-22. PMID:15008806. |
nicotine has a powerful preventive effect on neuroleptic-induced dopamine d2 receptor upregulation in the rat. |
2004-07-22 |
2023-08-12 |
human |
| Hui Zhang, David Sulze. Frequency-dependent modulation of dopamine release by nicotine. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146187. |
frequency-dependent modulation of dopamine release by nicotine. |
2004-07-20 |
2023-08-12 |
Not clear |
| Hui Zhang, David Sulze. Frequency-dependent modulation of dopamine release by nicotine. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146187. |
although nicotine activation of dopamine release is implicated in addiction, it also desensitizes nicotinic acetylcholine receptors (nachrs), leading to a prolonged depression of evoked dopamine release. |
2004-07-20 |
2023-08-12 |
Not clear |
| Hui Zhang, David Sulze. Frequency-dependent modulation of dopamine release by nicotine. Nature neuroscience. vol 7. issue 6. 2004-07-20. PMID:15146187. |
here we show that nicotine's effects depend on the firing pattern of dopamine neurons, so that while desensitization of nachrs indeed curbs dopamine released by stimuli emulating tonic firing, it allows a rapid rise in dopamine from stimuli emulating phasic firing patterns associated with incentive/salience paradigms. |
2004-07-20 |
2023-08-12 |
Not clear |