| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Massimo Grilli, Monica Parodi, Maurizio Raiteri, Mario March. Chronic nicotine differentially affects the function of nicotinic receptor subtypes regulating neurotransmitter release. Journal of neurochemistry. vol 93. issue 5. 2005-06-24. PMID:15934954. |
in striatal synaptosomes, prelabelled with [3h]dopamine (da), chronic nicotine did not modify the releasing effect of nicotine. |
2005-06-24 |
2023-08-12 |
rat |
| R Moaddel, R Yamaguchi, P C Ho, S Patel, C-P Hsu, V Subrahmanyam, I W Waine. Development and characterization of an immobilized human organic cation transporter based liquid chromatographic stationary phase. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 818. issue 2. 2005-06-23. PMID:15734168. |
columns were created using both stationary phases, and frontal displacement chromatography experiments were conducted using [(3)h]-methyl phenyl pyridinium ([(3)h]-mpp(+)) as the marker ligand and mpp(+), verapamil, quinidine, quinine, nicotine, dopamine and vinblastin as the displacers. |
2005-06-23 |
2023-08-12 |
human |
| Albert Lai, Neeraja Parameswaran, Mirium Khwaja, Paul Whiteaker, Jon M Lindstrom, Hong Fan, J Michael McIntosh, Sharon R Grady, Maryka Qui. Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice. Molecular pharmacology. vol 67. issue 5. 2005-06-15. PMID:15681595. |
a decline was obtained with nicotine treatment that was caused by a selective decrease in alpha-conotoxin mii-sensitive but not alpha-conotoxin mii-resistant dopamine release. |
2005-06-15 |
2023-08-12 |
mouse |
| Albert Lai, Neeraja Parameswaran, Mirium Khwaja, Paul Whiteaker, Jon M Lindstrom, Hong Fan, J Michael McIntosh, Sharon R Grady, Maryka Qui. Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice. Molecular pharmacology. vol 67. issue 5. 2005-06-15. PMID:15681595. |
these results may explain previous findings that nicotine treatment decreased striatal nachr-mediated dopamine function, despite an increase in [3h]nicotine (alpha4*) sites. |
2005-06-15 |
2023-08-12 |
mouse |
| Albert Lai, Neeraja Parameswaran, Mirium Khwaja, Paul Whiteaker, Jon M Lindstrom, Hong Fan, J Michael McIntosh, Sharon R Grady, Maryka Qui. Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice. Molecular pharmacology. vol 67. issue 5. 2005-06-15. PMID:15681595. |
the present data suggest that the alpha6* nachr subtype represents a key factor in the control of dopamine release from striatum, which adapts to long-term nicotine treatment by down-regulation of alpha6* receptor sites and function. |
2005-06-15 |
2023-08-12 |
mouse |
| E Sylvester Vizi, Balázs Rózsa, Aliz Mayer, János P Kiss, Tibor Zelles, Balázs Lendva. Further evidence for the functional role of nonsynaptic nicotinic acetylcholine receptors. European journal of pharmacology. vol 500. issue 1-3. 2005-06-14. PMID:15464055. |
we also investigated the role of nicotinic receptors in the nucleus accumbens where nicotine stimulated vesicular dopamine release via activation of receptors located on varicosities. |
2005-06-14 |
2023-08-12 |
Not clear |
| E Sylvester Vizi, Balázs Rózsa, Aliz Mayer, János P Kiss, Tibor Zelles, Balázs Lendva. Further evidence for the functional role of nonsynaptic nicotinic acetylcholine receptors. European journal of pharmacology. vol 500. issue 1-3. 2005-06-14. PMID:15464055. |
nicotine produced comparable effects with 3,4-methylenedioxymethamphetamine (mdma, ecstasy) on dopamine release. |
2005-06-14 |
2023-08-12 |
Not clear |
| Brian A McMillen, Barbara J Davis, Helen L Williams, Ken Soderstro. Periadolescent nicotine exposure causes heterologous sensitization to cocaine reinforcement. European journal of pharmacology. vol 509. issue 2-3. 2005-06-14. PMID:15733551. |
thus, periadolescent nicotine exposure produced long-term sensitization to an indirect-acting dopamine agonist. |
2005-06-14 |
2023-08-12 |
rat |
| David J K Balfou. The neurobiology of tobacco dependence: a preclinical perspective on the role of the dopamine projections to the nucleus accumbens [corrected]. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 6. issue 6. 2005-05-10. PMID:15801566. |
it focuses on the hypothesis that stimulation of the dopamine (da) projections to the medial shell and the core of the nucleus accumbens play complementary roles in the development of nicotine dependence. |
2005-05-10 |
2023-08-12 |
Not clear |
| Susan Wonnacott, Nimish Sidhpura, David J K Balfou. Nicotine: from molecular mechanisms to behaviour. Current opinion in pharmacology. vol 5. issue 1. 2005-05-04. PMID:15661626. |
nicotine, like other addictive drugs including psychomotor stimulants, promotes dopamine release in the nucleus accumbens. |
2005-05-04 |
2023-08-12 |
Not clear |
| Karin Schwartz, Abraham Weizman, Moshe Rehav. Decreased platelet vesicular monoamine transporter density in habitual smokers. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 2. 2005-05-03. PMID:15695071. |
nicotine induced increase of dopamine and serotonin neurotransmission in limbic structures may alter the expression of vmat2 in brains of smokers. |
2005-05-03 |
2023-08-12 |
Not clear |
| P Rada, D F Johnson, M J Lewis, B G Hoebe. In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal. Pharmacology, biochemistry, and behavior. vol 79. issue 4. 2005-04-29. PMID:15582668. |
as with the withdrawal from morphine, nicotine, diazepam and sugar, the ethanol withdrawal state may involve an increase in nucleus accumbens (nac) acetylcholine (ach) causing an alteration of the dopamine (da)-ach balance in favor of ach. |
2005-04-29 |
2023-08-12 |
rat |
| Ying-Jun Cao, Carol S Surowy, Pamela S Puttfarcke. Different nicotinic acetylcholine receptor subtypes mediating striatal and prefrontal cortical [3H]dopamine release. Neuropharmacology. vol 48. issue 1. 2005-04-28. PMID:15617729. |
compared to nicotine, (+/-)-ub-165 showed less efficacy with respect to dopamine release from striatum, and had no effect on cortical dopamine release. |
2005-04-28 |
2023-08-12 |
Not clear |
| Stephanie L Collins, Dean Wade, Jennifer Ledon, Sari Izenwasse. Neurochemical alterations produced by daily nicotine exposure in periadolescent vs. adult male rats. European journal of pharmacology. vol 502. issue 1-2. 2005-04-08. PMID:15464092. |
nicotine treatment increased dopamine transporter densities and decreased serotonin transporter densities in periadolescent rats. |
2005-04-08 |
2023-08-12 |
rat |
| Stephanie L Collins, Dean Wade, Jennifer Ledon, Sari Izenwasse. Neurochemical alterations produced by daily nicotine exposure in periadolescent vs. adult male rats. European journal of pharmacology. vol 502. issue 1-2. 2005-04-08. PMID:15464092. |
in adult rats pretreated with nicotine, there was an increase in nicotinic acetylcholine densities, but no change in dopamine transporter, dopamine d1 or d2 receptor, or serotonin transporter densities. |
2005-04-08 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. Regional heterogeneity of nicotine effects on neurotransmitters in rat brains in vivo at low doses. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756937. |
in our recent studies on nicotine-induced changes in neurotransmitters in brain areas associated with cognitive function using a nicotine dose of 0.5 mg/kg administered subcutaneously to conscious freely moving rats, we found changes in dopamine, norepinephrine, and serotonin, and their metabolites, in the areas examined. |
2005-04-08 |
2023-08-12 |
rat |
| Sabina H L de Villiers, Nina Lindblom, Genadiy Kalayanov, Sandra Gordon, Anette M Johansson, Torgny H Svensso. Active immunization against nicotine alters the distribution of nicotine but not the metabolism to cotinine in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 370. issue 4. 2005-03-23. PMID:15375641. |
we have previously shown that active immunization with the nicotine immunoconjugate ip18-klh attenuates the reinforcing effects of nicotine, i.e., suppresses the nicotine-induced brain dopamine release and prevents reinstatement of the nicotine-seeking behavior in rats. |
2005-03-23 |
2023-08-12 |
rat |
| Vladimir P Grinevich, Sharon R Letchworth, Kari A Lindenberger, Jean Menager, Veronique Mary, Khalima A Sadieva, Lori M Buhlman, Georg Andrees Bohme, Laurent Pradier, Jesus Benavides, Ronald J Lukas, Merouane Bencheri. Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit. The Journal of pharmacology and experimental therapeutics. vol 312. issue 2. 2005-03-18. PMID:15356217. |
the rank order of binding competition potency (k(i)) for prototypical nicotinic compounds was alpha-conotoxin mii (6 nm) > nicotine (156 nm) approximately methyllycaconitine (200 nm) > alpha-bungarotoxin (>10 microm), similar to that for nachr in dopamine neurons displaying a distinctive pharmacology. |
2005-03-18 |
2023-08-12 |
human |
| Shu-Peng Li, Moon Seok Park, Jong Hun Kim, Myeong Ok Ki. Chronic nicotine and smoke treatment modulate dopaminergic activities in ventral tegmental area and nucleus accumbens and the gamma-aminobutyric acid type B receptor expression of the rat prefrontal cortex. Journal of neuroscience research. vol 78. issue 6. 2005-03-07. PMID:15521060. |
to explore further the relationship between the mesencephalic dopaminergic neurons and pfc gabaergic neurons, we investigated the effects of nicotine and passive exposure to cigarette smoke on the regulation of tyrosine hydroxylase (th) in vta and substantia nigra (snc) and dopamine (da) d1 receptor levels in nucleus accumbens (nac) and caudate-putamen (cpu). |
2005-03-07 |
2023-08-12 |
rat |
| Sanna Janhunen, Liisa Ahte. Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. European journal of pharmacology. vol 494. issue 2-3. 2005-02-14. PMID:15212971. |
comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. |
2005-02-14 |
2023-08-12 |
rat |