| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rong Jie Zhao, Byung Soo Koo, Geun Woo Kim, Eun Young Jang, Jong Rok Lee, Mi Ryeo Kim, Sang Chan Kim, Young Kyu Kwon, Kwang Joong Kim, Tae-lin Huh, Dae-Hyun Kim, Insop Shim, Chae Ha Yan. The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization. Biological & pharmaceutical bulletin. vol 28. issue 12. 2006-03-09. PMID:16327174. |
most importantly, our results showed that inhalation of the essential oils from angelica gigas nakai significantly decreased both dopamine release in the nucleus accumbens and locomotor activity induced by a nicotine challenge. |
2006-03-09 |
2023-08-12 |
rat |
| Rong Jie Zhao, Byung Soo Koo, Geun Woo Kim, Eun Young Jang, Jong Rok Lee, Mi Ryeo Kim, Sang Chan Kim, Young Kyu Kwon, Kwang Joong Kim, Tae-lin Huh, Dae-Hyun Kim, Insop Shim, Chae Ha Yan. The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization. Biological & pharmaceutical bulletin. vol 28. issue 12. 2006-03-09. PMID:16327174. |
these results suggest that the essential oils from angelica gigas nakai inhibit nicotine-induced behavioral and neurochemical sensitization, and imply that the essential oil from angelica gigas nakai may be effective in treating nicotine addiction, possibly by modulating dopamine release in the nucleus accumbens. |
2006-03-09 |
2023-08-12 |
rat |
| Richard De La Garz. Wistar Kyoto rats exhibit reduced sucrose pellet reinforcement behavior and intravenous nicotine self-administration. Pharmacology, biochemistry, and behavior. vol 82. issue 2. 2006-03-02. PMID:16226802. |
on the basis of previously published findings, we hypothesize that altered mesolimbic dopamine responses, as well as heightened hpa axis functioning, may account for reduced nicotine self-administration and sucrose pellet reinforcement responding in wky rats. |
2006-03-02 |
2023-08-12 |
rat |
| Sangeetha P Sumithran, Peter A Crooks, Rui Xu, Jun Zhu, Agripina G Deaciuc, Lincoln H Wilkins, Linda P Dwoski. Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity. The AAPS journal. vol 7. issue 1. 2006-02-23. PMID:16146341. |
n-n-octylnicotinium iodide (noni) and n-n-decylnicotinium iodide (ndni) are selective nicotinic receptor (nachr) antagonists mediating nicotine-evoked striatal dopamine (da) release, and inhibiting [3h]nicotine binding, respectively. |
2006-02-23 |
2023-08-12 |
Not clear |
| Charlotte Warner, Mohammed Shoai. How does bupropion work as a smoking cessation aid? Addiction biology. vol 10. issue 3. 2006-02-08. PMID:16109583. |
this review led to several conclusions: (1) the principal mode of bupropion action is upon the withdrawal symptoms following smoking cessation; (2) during withdrawal, bupropion may attenuate symptoms by mimicking nicotinic effects on dopamine and noradrenaline; (3) its ability to antagonize nicotinic receptors may prevent relapse by attenuating the reinforcing properties of nicotine, but probably cannot acutely reduce smoking; and (4) further exploration of bupropion metabolites and its role in withdrawal and relapse, within more appropriate animal models, could be crucial in the determination of the precise mechanisms by which bupropion exerts its activity in smoking cessation. |
2006-02-08 |
2023-08-12 |
Not clear |
| Lieuwe de Haan, Jan Booij, Jules Lavalaye, Therese van Amelsvoort, Don Linsze. Occupancy of dopamine D2 receptors by antipsychotic drugs is related to nicotine addiction in young patients with schizophrenia. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16292589. |
occupancy of dopamine d2 receptors by antipsychotic drugs is related to nicotine addiction in young patients with schizophrenia. |
2006-01-31 |
2023-08-12 |
Not clear |
| Hideo Tsukada, Katsumasa Miyasato, Shingo Nishiyama, Dai Fukumoto, Takeharu Kakiuchi, Edward F Domin. Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 12. 2006-01-24. PMID:15856080. |
nicotine normalizes increased prefrontal cortical dopamine d1 receptor binding and decreased working memory performance produced by repeated pretreatment with mk-801: a pet study in conscious monkeys. |
2006-01-24 |
2023-08-12 |
monkey |
| Hideo Tsukada, Katsumasa Miyasato, Shingo Nishiyama, Dai Fukumoto, Takeharu Kakiuchi, Edward F Domin. Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 12. 2006-01-24. PMID:15856080. |
the effects of acute nicotine were determined on dopamine (da) d(1) (d(1)r) and d(2) (d(2)r) receptor binding in the neocortex of conscious monkeys under control conditions as well as after chronic pretreatment with mk-801 (dizocilpine), a noncompetitive n-methyl-d-aspartate (nmda) receptor antagonist. |
2006-01-24 |
2023-08-12 |
monkey |
| David G Gilbert, Adam Izetelny, Robert Radtke, Jonathan Hammersley, Norka E Rabinovich, Travis R Jameson, Jodi I Huggenvi. Dopamine receptor (DRD2) genotype-dependent effects of nicotine on attention and distraction during rapid visual information processing. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 7. issue 3. 2006-01-23. PMID:16085504. |
the effects of nicotine, distractor type, and dopamine type-2 receptor (drd2) genotype on rapid visual information processing (rvip) task performance were assessed in habitual smokers. |
2006-01-23 |
2023-08-12 |
human |
| K J Gill, A E Boyl. Genetic basis for the psychostimulant effects of nicotine: a quantitative trait locus analysis in AcB/BcA recombinant congenic mice. Genes, brain, and behavior. vol 4. issue 7. 2006-01-23. PMID:16176386. |
a number of putative candidate genes were in proximity to regions identified with nicotine sensitivity, including the alpha2 subunit of the nicotinic acetylcholine receptor and the dopamine d3 receptor. |
2006-01-23 |
2023-08-12 |
mouse |
| S Mexal, M Frank, R Berger, C E Adams, R G Ross, R Freedman, S Leonar. Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Brain research. Molecular brain research. vol 139. issue 2. 2006-01-17. PMID:16122832. |
nicotine is known to induce the release of multiple neurotransmitters, including glutamate and dopamine, through activation of nicotinic receptors. |
2006-01-17 |
2023-08-12 |
human |
| Miho Hamada, Joseph P Hendrick, Gregory R Ryan, Mahomi Kuroiwa, Hideho Higashi, Masatoshi Tanaka, Angus C Nairn, Paul Greengard, Akinori Nish. Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of pharmacology and experimental therapeutics. vol 315. issue 2. 2006-01-12. PMID:16040813. |
we have recently reported that nicotine stimulates the release of dopamine via alpha4beta2(*) nachrs and/or alpha7 nachrs, leading to the regulation of darpp-32 at thr34, the site involved in regulation of protein phosphatase-1 (pp-1). |
2006-01-12 |
2023-08-12 |
Not clear |
| Miho Hamada, Joseph P Hendrick, Gregory R Ryan, Mahomi Kuroiwa, Hideho Higashi, Masatoshi Tanaka, Angus C Nairn, Paul Greengard, Akinori Nish. Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of pharmacology and experimental therapeutics. vol 315. issue 2. 2006-01-12. PMID:16040813. |
these various actions of nicotine on modulatory sites of phosphorylation would be predicted to result in a synergistic increase in the state of phosphorylation of darpp-32 at thr34 and thus would contribute to increased dopamine d1 receptor/darpp-32 thr34/pp-1 signaling. |
2006-01-12 |
2023-08-12 |
Not clear |
| Vladimir A Kashkin, Philippe De Witt. Nicotine increases microdialysate brain amino acid concentrations and induces conditioned place preference. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 6. 2006-01-05. PMID:15916885. |
the same doses of nicotine were able to elicit a reinforcing effect in a cpp paradigm which was probably associated with the increased brain levels of excitatory acids triggering additional dopamine release in the mesolimbic system. |
2006-01-05 |
2023-08-12 |
rat |
| Robert H Grange. Oxygen as a therapy for reducing nicotine withdrawal symptoms. Medical hypotheses. vol 65. issue 6. 2006-01-05. PMID:16002232. |
the use of nicotine replacement therapies and zyban (sustained release bupropion hydrochloride), both of which are suspected of exploiting dopamine's role in addiction, enhance the likelihood of long-term smoking cessation. |
2006-01-05 |
2023-08-12 |
Not clear |
| Robert H Grange. Oxygen as a therapy for reducing nicotine withdrawal symptoms. Medical hypotheses. vol 65. issue 6. 2006-01-05. PMID:16002232. |
oxygen may have a favorable effect on nicotine withdrawal, as it appears to alter the balance of central neurotransmitters such as dopamine. |
2006-01-05 |
2023-08-12 |
Not clear |
| M Picciolo, D Gigante, A Nunziat. [Nicotine addiction and current therapy of smoking cessation]. La Clinica terapeutica. vol 156. issue 4. 2006-01-04. PMID:16342517. |
nicotine is defined as substance which provokes addiction because it creates both physiological and biochemical modifications in the nervous system stimulating the activity of dopaminergic neurons releasing dopamine in the areas of the brain that control pleasure. |
2006-01-04 |
2023-08-12 |
Not clear |
| Mohammad Tariq, Haseeb Ahmad Khan, Ibrahim Elfaki, Saleh Al Deeb, Khalaf Al Moutaer. Neuroprotective effect of nicotine against 3-nitropropionic acid (3-NP)-induced experimental Huntington's disease in rats. Brain research bulletin. vol 67. issue 1-2. 2005-12-13. PMID:16140176. |
administration of 3-np alone caused significant depletion of striatal dopamine (da) and glutathione (gsh), which was significantly and dose-dependently attenuated by nicotine. |
2005-12-13 |
2023-08-12 |
rat |
| Hao Chen, Steven L Parker, Shannon G Matta, Burt M Shar. Gestational nicotine exposure reduces nicotinic cholinergic receptor (nAChR) expression in dopaminergic brain regions of adolescent rats. The European journal of neuroscience. vol 22. issue 2. 2005-09-23. PMID:16045491. |
we previously reported that gestational nicotine exposure attenuated dopamine release induced by nicotine delivered during adolescence. |
2005-09-23 |
2023-08-12 |
human |
| Fernando Berrendero, Victoria Mendizábal, Patricia Robledo, Lola Galeote, Andras Bilkei-Gorzo, Andreas Zimmer, Rafael Maldonad. Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 5. 2005-09-13. PMID:15689546. |
accordingly, in vivo microdialysis studies revealed that the enhancement in dopamine extracellular levels in the nucleus accumbens induced by nicotine was also reduced in preproenkephalin-deficient mice. |
2005-09-13 |
2023-08-12 |
mouse |