| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Björn Schilström, Vladimir B Ivanov, Charlotte Wiker, Torgny H Svensso. Galantamine enhances dopaminergic neurotransmission in vivo via allosteric potentiation of nicotinic acetylcholine receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 1. 2007-02-09. PMID:16641937. |
we have previously shown that nicotine, through stimulation of nachrs in the ventral tegmental area (vta), activates midbrain dopamine neurons and, hence, potentiation of these receptors could be an additional mechanism by which galantamine can activate dopaminergic pathways. |
2007-02-09 |
2023-08-12 |
rat |
| b' Davide Quarta, Francisco Ciruela, Kshitij Patkar, Janusz Borycz, Marcello Solinas, Carme Lluis, Rafael Franco, Roy A Wise, Steven R Goldberg, Bruce T Hope, Amina S Woods, Sergi Ferr\\xc3\\xa. Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 1. 2007-02-09. PMID:16710311.' |
local perfusion of nicotine in the ventral striatum (shell of the nucleus accumbens) produced a marked increase in the extracellular levels of dopamine, which was completely counteracted by co-perfusion with either the non-alpha(7) nach receptor antagonist dihydro-beta-erythroidine or the d(2-3) receptor agonist quinpirole. |
2007-02-09 |
2023-08-12 |
rat |
| Soo Kyung Hong, In Soon Jung, Seong Ae Bang, Sang Eun Ki. Effect of nitric oxide synthase inhibitor and NMDA receptor antagonist on the development of nicotine sensitization of nucleus accumbens dopamine release: an in vivo microdialysis study. Neuroscience letters. vol 409. issue 3. 2007-01-04. PMID:17046158. |
effect of nitric oxide synthase inhibitor and nmda receptor antagonist on the development of nicotine sensitization of nucleus accumbens dopamine release: an in vivo microdialysis study. |
2007-01-04 |
2023-08-12 |
rat |
| Soo Kyung Hong, In Soon Jung, Seong Ae Bang, Sang Eun Ki. Effect of nitric oxide synthase inhibitor and NMDA receptor antagonist on the development of nicotine sensitization of nucleus accumbens dopamine release: an in vivo microdialysis study. Neuroscience letters. vol 409. issue 3. 2007-01-04. PMID:17046158. |
this study aimed to investigate the effect of l-nna and mk-801 on a neurochemical component of nicotine sensitization by evaluating the effect of the drugs on nicotine sensitization of nucleus accumbens dopamine (da) release. |
2007-01-04 |
2023-08-12 |
rat |
| Anna Castañé, Guadalupe Soria, Catherine Ledent, Rafael Maldonado, Olga Valverd. Attenuation of nicotine-induced rewarding effects in A2A knockout mice. Neuropharmacology. vol 51. issue 3. 2006-12-14. PMID:16793068. |
accordingly, in vivo microdialysis studies revealed that the extracellular levels of dopamine in the nucleus accumbens were not increased after nicotine administration in mutant mice. |
2006-12-14 |
2023-08-12 |
mouse |
| Kevin F Casey, Chawki Benkelfat, Simon N Young, Marco Leyto. Lack of effect of acute dopamine precursor depletion in nicotine-dependent smokers. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 16. issue 7. 2006-11-14. PMID:16545549. |
nicotine increases dopamine (da) release but its role in nicotine dependence remains unclear. |
2006-11-14 |
2023-08-12 |
Not clear |
| Anne-Sophie Villégier, Lucas Salomon, Gérard Blanc, Gérard Godeheu, Jacques Glowinski, Jean-Pol Tassi. Irreversible blockade of monoamine oxidases reveals the critical role of 5-HT transmission in locomotor response induced by nicotine in mice. The European journal of neuroscience. vol 24. issue 5. 2006-11-14. PMID:16965547. |
we show here that when mice were pretreated with enhancers of extracellular levels of noradrenaline, dopamine or serotonin (d-amphetamine, gbr12783 or para-chloro-amphetamine, respectively) and injected with nicotine (1 mg/kg), only those animals pretreated with para-chloro-amphetamine exhibited a specific locomotor response to nicotine. |
2006-11-14 |
2023-08-12 |
mouse |
| Maryka Quik, Neeraja Parameswaran, Sarah E McCallum, Tanuja Bordia, Shanshan Bao, Alison McCormack, Amy Kim, Rachel F Tyndale, J William Langston, Donato A Di Mont. Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. Journal of neurochemistry. vol 98. issue 6. 2006-11-07. PMID:16882311. |
the results showed that levels of striatal tyrosine hydroxylase, dopamine transporter, vesicular monoamine transporter, dopamine and nicotinic receptors were greater in nicotine-treated mptp-lesioned primates than in lesioned animals not receiving nicotine. |
2006-11-07 |
2023-08-12 |
monkey |
| Maryka Quik, Neeraja Parameswaran, Sarah E McCallum, Tanuja Bordia, Shanshan Bao, Alison McCormack, Amy Kim, Rachel F Tyndale, J William Langston, Donato A Di Mont. Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. Journal of neurochemistry. vol 98. issue 6. 2006-11-07. PMID:16882311. |
monoamine oxidase activity was similar in unlesioned and lesioned animals treated with or without nicotine, suggesting that nicotine did not exert its effects through changes in mptp or dopamine metabolism. |
2006-11-07 |
2023-08-12 |
monkey |
| Tanja Vihavainen, Jelena Mijatovic, T Petteri Piepponen, Raimo K Tuominen, Liisa Ahte. Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice. Behavioural brain research. vol 173. issue 1. 2006-10-12. PMID:16846651. |
in the present study mice withdrawn from a 7-week oral nicotine treatment were administered morphine, following which their locomotor activities were recorded and the concentrations of dopamine, 5-hydroxytryptamine (5-ht), noradrenaline and their metabolites were measured in the caudate putamen (cpu) and nucleus accumbens (nac). |
2006-10-12 |
2023-08-12 |
mouse |
| Daniele Lecca, Fabio Cacciapaglia, Valentina Valentini, Janne Gronli, Saturnino Spiga, Gaetano Di Chiar. Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration. Psychopharmacology. vol 184. issue 3-4. 2006-10-06. PMID:16397746. |
preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration. |
2006-10-06 |
2023-08-12 |
rat |
| Daniele Lecca, Fabio Cacciapaglia, Valentina Valentini, Janne Gronli, Saturnino Spiga, Gaetano Di Chiar. Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration. Psychopharmacology. vol 184. issue 3-4. 2006-10-06. PMID:16397746. |
it has been reported that passive administration of nicotine increases preferentially extracellular dopamine (da) release in the shell as compared to that in the core of the nucleus accumbens (nac). |
2006-10-06 |
2023-08-12 |
rat |
| Vincent David, Morgane Besson, Jean-Pierre Changeux, Sylvie Granon, Pierre Cazal. Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology. vol 50. issue 8. 2006-09-28. PMID:16580026. |
we then challenged intra-vta nicotine self-administration via systemic or local injections of dopamine (da)-d1 and nicotinic receptor antagonists. |
2006-09-28 |
2023-08-12 |
mouse |
| Katsuya Suemaru, Kayo Yasuda, Ranji Cui, Bingjin Li, Kenta Umeda, Manabu Amano, Hiromi Mitsuhashi, Nobuhito Takeuchi, Tomoyoshi Inoue, Yutaka Gomita, Hiroaki Arak. Antidepressant-like action of nicotine in forced swimming test and brain serotonin in mice. Physiology & behavior. vol 88. issue 4-5. 2006-09-28. PMID:16766001. |
dopamine turnover in mouse whole brain was increased by nicotine (0.01-1 mg/kg, s.c.) in a dose-dependent manner, and nicotine at a dose of 0.05 mg/kg showed a significant increases in 5-ht turnover. |
2006-09-28 |
2023-08-12 |
mouse |
| Sarah E McCallum, Neeraja Parameswaran, Tanuja Bordia, Hong Fan, J Michael McIntosh, Maryka Qui. Differential regulation of mesolimbic alpha 3/alpha 6 beta 2 and alpha 4 beta 2 nicotinic acetylcholine receptor sites and function after long-term oral nicotine to monkeys. The Journal of pharmacology and experimental therapeutics. vol 318. issue 1. 2006-08-14. PMID:16622038. |
because the mesolimbic dopamine system plays a critical role in nicotine addiction/reinforcement and because nicotinic receptors regulate dopamine release, we initiated a study to evaluate the long-term effects of nicotine (>6 months at the final dose) on nicotinic acetylcholine receptor (nachr) sites and function in the nucleus accumbens of nonhuman primates. |
2006-08-14 |
2023-08-12 |
mouse |
| Sarah E McCallum, Neeraja Parameswaran, Tanuja Bordia, Hong Fan, J Michael McIntosh, Maryka Qui. Differential regulation of mesolimbic alpha 3/alpha 6 beta 2 and alpha 4 beta 2 nicotinic acetylcholine receptor sites and function after long-term oral nicotine to monkeys. The Journal of pharmacology and experimental therapeutics. vol 318. issue 1. 2006-08-14. PMID:16622038. |
to evaluate function, we measured nicotine and k+-evoked [3h]dopamine release from nucleus accumbens synaptosomes. |
2006-08-14 |
2023-08-12 |
mouse |
| Qiang Liu, Zhen Li, Jian-Hua Ding, Su-Yi Liu, Jie Wu, Gang H. Iptakalim inhibits nicotine-induced enhancement of extracellular dopamine and glutamate levels in the nucleus accumbens of rats. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16647046. |
the results show that acute nicotine treatment induced an increase of both dopamine and glutamate levels in the rat nac, and that ipt significantly attenuated nicotine's effects in a concentration-dependent manner. |
2006-08-10 |
2023-08-12 |
rat |
| Qiang Liu, Zhen Li, Jian-Hua Ding, Su-Yi Liu, Jie Wu, Gang H. Iptakalim inhibits nicotine-induced enhancement of extracellular dopamine and glutamate levels in the nucleus accumbens of rats. Brain research. vol 1085. issue 1. 2006-08-10. PMID:16647046. |
therefore, ipt may serve as a novel compound to block nicotine-induced dopamine and glutamate release in the brain reward center, in turn decreasing nicotine reinforcement and dependence. |
2006-08-10 |
2023-08-12 |
rat |
| Sietse Jonkman, Athina Marko. Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats. Neuroscience letters. vol 400. issue 1-2. 2006-08-04. PMID:16563623. |
blockade of nicotinic acetylcholine or dopamine d1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats. |
2006-08-04 |
2023-08-12 |
rat |
| Arthur L Brody, Mark A Mandelkern, Richard E Olmstead, David Scheibal, Emily Hahn, Sharon Shiraga, Eleanor Zamora-Paja, Judah Farahi, Sanjaya Saxena, Edythe D London, James T McCracke. Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens. Archives of general psychiatry. vol 63. issue 7. 2006-08-03. PMID:16818870. |
preclinical studies demonstrate that nicotine administration leads to dopamine release in the ventral striatum. |
2006-08-03 |
2023-08-12 |
human |