| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wade H Berrettini, Caryn E Lerma. Pharmacotherapy and pharmacogenetics of nicotine dependence. The American journal of psychiatry. vol 162. issue 8. 2005-09-09. PMID:16055765. |
the initial pharmacogenetic studies of pharmacotherapies approved by the united states food and drug administration for treatment of nicotine dependence-nicotine replacement (nicotine gum, nicotine nasal spray, and transdermal nicotine) and bupropion-have identified candidate alleles at the dopamine d2 receptor gene and mu opioid receptor gene that may predict therapeutic response. |
2005-09-09 |
2023-08-12 |
Not clear |
| Caroline Cohen, Ercem Kodas, Guy Griebe. CB1 receptor antagonists for the treatment of nicotine addiction. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15935455. |
the addictive effect of nicotine is mediated by activation of the mesolimbic system and the release of dopamine in the nucleus accumbens. |
2005-09-08 |
2023-08-12 |
mouse |
| Hideo Tsukada, Katsumasa Miyasato, Norihiro Harada, Shingo Nishiyama, Dai Fukumoto, Takeharu Kakiuch. Nicotine modulates dopamine synthesis rate as determined by L-[beta-11C]DOPA: PET studies compared with [11C]raclopride binding in the conscious monkey brain. Synapse (New York, N.Y.). vol 57. issue 2. 2005-08-30. PMID:15906385. |
nicotine modulates dopamine synthesis rate as determined by l-[beta-11c]dopa: pet studies compared with [11c]raclopride binding in the conscious monkey brain. |
2005-08-30 |
2023-08-12 |
monkey |
| Anne Borgne, Henri-Jean Aubin, Ivan Berli. [Current therapeutic strategies in smoking cessation]. La Revue du praticien. vol 54. issue 17. 2005-08-26. PMID:15655912. |
these are: brief advice, assessing the smoking status of each patient and encouraging cessation; nicotine replacement therapies (nrt) [transdermal patch, gum, sublingual tablet or inhalator to be used at sufficiently individualised doses combining, if necessary, two or more nrt products]; bupropion, a more recent treatment: psychotropic drug, a noradrenaline and dopamine re-uptake inhibitor more recently approved for marketing; behavioural and cognitive therapies on their own or combined with pharmacotherapy. |
2005-08-26 |
2023-08-12 |
Not clear |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
nicotine alone induced an increase of dopamine and its metabolites in all areas, an increase of norepinephrine in the cortex, and an increase of the norepinephrine metabolite 4-hydroxy-3-methoxy-phenylglycol in all areas. |
2005-08-24 |
2023-08-12 |
rat |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. The effects of cholinergic and dopaminergic antagonists on nicotine-induced cerebral neurotransmitter changes. Neurochemical research. vol 30. issue 4. 2005-08-24. PMID:16076024. |
in the hippocampal and cortical areas, the mechanisms of nicotine-induced dopamine increase seem to be similar, but the mechanisms seem to be different for noradrenergic and serotonergic systems, as shown by the fact that nicotine induces no change in norepinephrine and a decrease in serotonin in the hippocampus, while it induces an increase in both in the cortex. |
2005-08-24 |
2023-08-12 |
rat |
| Jukka S Pakkanen, Eija Jokitalo, Raimo K Tuomine. Up-regulation of beta2 and alpha7 subunit containing nicotinic acetylcholine receptors in mouse striatum at cellular level. The European journal of neuroscience. vol 21. issue 10. 2005-08-17. PMID:15926916. |
nicotine releases dopamine in the brain by activating neuronal nicotinic acetylcholine receptors (nachrs). |
2005-08-17 |
2023-08-12 |
mouse |
| S Fenu, E Rivas, G Di Chiar. Differential role of dopamine in drug- and lithium-conditioned saccharin avoidance. Physiology & behavior. vol 85. issue 1. 2005-07-29. PMID:15924904. |
in the present study the involvement of dopamine (da) transmission in the acquisition of morphine, nicotine and lithium-conditioned csa was investigated in a two-bottle choice paradigm. |
2005-07-29 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. |
2005-07-26 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
we studied the effects of nicotine and epibatidine given in combination with dopamine uptake inhibitor, nomifensine, on striatal extracellular dopamine and its metabolites by using brain microdialysis in freely moving rats. |
2005-07-26 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
in the caudate-putamen, nicotine (0.5 mg/kg) and epibatidine (0.6 microg/kg but not 3.0 microg/kg) enhanced nomifensine's effect on dopamine. |
2005-07-26 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
the effect of nomifensine on accumbal dopamine was enhanced by nicotine, but inhibited by epibatidine at 0.6 microg/kg. |
2005-07-26 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
thus, the effects of the smaller epibatidine dose (0.6 microg/kg) on the dopamine output in the caudate-putamen but not in the accumbens resemble those of nicotine 0.5 mg/kg. |
2005-07-26 |
2023-08-12 |
rat |
| Sanna Janhunen, Raimo K Tuominen, T Petteri Piepponen, Liisa Ahte. Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. European journal of pharmacology. vol 511. issue 2-3. 2005-07-26. PMID:15792782. |
discrepancies in the effects of epibatidine and nicotine are most probably due to differences in their affinities to nicotinic receptor subtypes regulating dopamine release. |
2005-07-26 |
2023-08-12 |
rat |
| Timothy J Turne. Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 50. 2005-07-21. PMID:15601939. |
nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. |
2005-07-21 |
2023-08-12 |
Not clear |
| Timothy J Turne. Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 50. 2005-07-21. PMID:15601939. |
prolonged application of 10(-7) to 10(-5) m nicotine to striatal synaptosomes promoted a sustained efflux of [3h]dopamine. |
2005-07-21 |
2023-08-12 |
Not clear |
| Timothy J Turne. Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 50. 2005-07-21. PMID:15601939. |
thus, nicotine enhances dopamine release by two complementary actions mediated by discrete nachr subtypes and suggest that the alpha7 nachr-mediated pathway is tightly and specifically coupled to refilling of the rrp of vesicles in dopamine terminals. |
2005-07-21 |
2023-08-12 |
Not clear |
| U Maskos, B E Molles, S Pons, M Besson, B P Guiard, J-P Guilloux, A Evrard, P Cazala, A Cormier, M Mameli-Engvall, N Dufour, I Cloëz-Tayarani, A-P Bemelmans, J Mallet, A M Gardier, V David, P Faure, S Granon, J-P Changeu. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. vol 436. issue 7047. 2005-07-19. PMID:16001069. |
we demonstrate the efficient re-expression of electrophysiologically responsive, ligand-binding nicotinic acetylcholine receptors in dopamine-containing neurons of the vta, together with the recovery of nicotine-elicited dopamine release and nicotine self-administration. |
2005-07-19 |
2023-08-12 |
mouse |
| J Erblich, C Lerman, D W Self, G A Diaz, D H Bovbjer. Effects of dopamine D2 receptor (DRD2) and transporter (SLC6A3) polymorphisms on smoking cue-induced cigarette craving among African-American smokers. Molecular psychiatry. vol 10. issue 4. 2005-07-12. PMID:15381926. |
research in animals over the past decade has solidly established the central role of dopamine in cue-induced craving for addictive substances, including nicotine. |
2005-07-12 |
2023-08-12 |
Not clear |
| Takahiro Takimoto, Hayato Terayama, Chikako Waga, Takashi Okayama, Kazutaka Ikeda, Isao Fukunishi, Kazuhiko Iwahash. Cholecystokinin (CCK) and the CCKA receptor gene polymorphism, and smoking behavior. Psychiatry research. vol 133. issue 2-3. 2005-06-30. PMID:15740988. |
we analyzed genetic variants of the promoter region of the cholecystokinin (cck; which modulates the release of dopamine) gene, and intron 1 and exon 5 of the ccka receptor gene, and performed association analyses of nicotine dependence using an allele-specific amplification (asa) method and pcr-rflp methods. |
2005-06-30 |
2023-08-12 |
Not clear |