| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M F G Murphy, K Hey, E Johnstone, M Munafo, R Walton, B Willis, P J Harriso. Bromocriptine use is associated with decreased smoking rates. Addiction biology. vol 7. issue 3. 2002-12-19. PMID:12126493. |
this observation supports the role of dopamine in nicotine addiction, and suggests that bromocriptine-like drugs could be used effectively by pregnant women to aid cessation. |
2002-12-19 |
2023-08-12 |
Not clear |
| Maria A Sullivan, Lirio S Cove. Nicotine dependence: the role for antidepressants and anxiolytics. Current opinion in investigational drugs (London, England : 2000). vol 3. issue 2. 2002-12-17. PMID:12020058. |
nicotine stimulates the release of several neurotransmitters including dopamine, norepinephrine, acetylcholine, 5-hydroxytryptamine, gamma-aminobutyric acid (gaba) and endorphins [3]. |
2002-12-17 |
2023-08-12 |
Not clear |
| Helena Gäddnäs, T Petteri Piepponen, Liisa Ahte. Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine. Neuroscience letters. vol 330. issue 3. 2002-12-13. PMID:12270632. |
mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine. |
2002-12-13 |
2023-08-12 |
mouse |
| Helena Gäddnäs, T Petteri Piepponen, Liisa Ahte. Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine. Neuroscience letters. vol 330. issue 3. 2002-12-13. PMID:12270632. |
the role of nicotinic acetylcholine receptor (nachr) activation in accumbal dopamine (da) release during chronic continuous nicotine treatment was studied by in vivo microdialysis in freely-moving mice. |
2002-12-13 |
2023-08-12 |
mouse |
| Nicholas H Caskey, Murray E Jarvik, William C Wirshing, Damian C Madsen, Paula N Iwamoto-Schaap, Naomi I Eisenberger, Lorena Huerta, Scott M Terrace, Richard E Olmstea. Modulating tobacco smoking rates by dopaminergic stimulation and blockade. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 4. issue 3. 2002-11-07. PMID:12215234. |
in prior human studies, a dopaminergic antagonist, haloperidol, increased smoking and/or nicotine intake, and a dopamine agonist, bromocriptine, decreased smoking. |
2002-11-07 |
2023-08-12 |
human |
| Nicholas H Caskey, Murray E Jarvik, William C Wirshing, Damian C Madsen, Paula N Iwamoto-Schaap, Naomi I Eisenberger, Lorena Huerta, Scott M Terrace, Richard E Olmstea. Modulating tobacco smoking rates by dopaminergic stimulation and blockade. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 4. issue 3. 2002-11-07. PMID:12215234. |
these data support the hypothesis that nicotine mediates reinforcement from smoking via dopamine, and that smoking behavior can be manipulated within the same subjects in opposite directions by alternately stimulating and blocking dopamine. |
2002-11-07 |
2023-08-12 |
human |
| Wim Vleeming, Bisoen Rambali, Antoon Opperhuize. The role of nitric oxide in cigarette smoking and nicotine addiction. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 4. issue 3. 2002-11-07. PMID:12215243. |
this second form of exposure to no also inhibits the re-uptake of dopamine, which may contribute to dopaminergic receptor stimulation and thus to the acute rewarding effects of nicotine. |
2002-11-07 |
2023-08-12 |
Not clear |
| Wim Vleeming, Bisoen Rambali, Antoon Opperhuize. The role of nitric oxide in cigarette smoking and nicotine addiction. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 4. issue 3. 2002-11-07. PMID:12215243. |
no may contribute to the development of cigarette smoking and nicotine addiction since: (1) inhaled no from smoke may be able to increase nicotine absorption, (2) no released through nicotine reduces symptoms of stress, (3) no endogenously released by nicotine increases post-synaptic dopamine levels, and (4) nos inhibitors attenuate symptoms of the nicotine abstinence syndrome. |
2002-11-07 |
2023-08-12 |
Not clear |
| Peter G Shield. Molecular epidemiology of smoking and lung cancer. Oncogene. vol 21. issue 45. 2002-11-05. PMID:12362269. |
they govern smoking behavior (affecting dopamine reward mechanisms due to nicotine and nicotine metabolism), carcinogen metabolism and detoxification, dna repair, cell cycle control and other cellular responses. |
2002-11-05 |
2023-08-12 |
Not clear |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
nicotine or cocaine, when administered intravenously, induces an increase of extracellular dopamine in the nucleus accumbens. |
2002-10-04 |
2023-08-12 |
Not clear |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
we assayed inhibition of the increase of dopamine in the nucleus accumbens induced by intravenous nicotine or cocaine administration by antagonists administered into the ventral tegmental area. |
2002-10-04 |
2023-08-12 |
Not clear |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
the findings indicate that a number of receptors in the ventral tegmental area mediate nicotine-induced dopamine changes in the nucleus accumbens, a major component of the nicotine reward mechanism. |
2002-10-04 |
2023-08-12 |
Not clear |
| Istvan Sziráki, Henry Sershen, Audrey Hashim, Abel Lajth. Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 27. issue 3. 2002-10-04. PMID:11958525. |
the importance of local receptors in the ventral tegmental area was further indicated by the increase in accumbal dopamine levels after intrategmental administration of nicotine or also cocaine. |
2002-10-04 |
2023-08-12 |
Not clear |
| Hideo Tsukada, Katsumasa Miyasato, Takeharu Kakiuchi, Shingo Nishiyama, Norihiro Harada, Edward F Domin. Comparative effects of methamphetamine and nicotine on the striatal [(11)C]raclopride binding in unanesthetized monkeys. Synapse (New York, N.Y.). vol 45. issue 4. 2002-09-13. PMID:12125041. |
although a very large literature exists on the in vitro, ex vivo, and in vivo effects of nicotine on dopamine release in rodents, similar data in primates are scant. |
2002-09-13 |
2023-08-12 |
monkey |
| Hideo Tsukada, Katsumasa Miyasato, Takeharu Kakiuchi, Shingo Nishiyama, Norihiro Harada, Edward F Domin. Comparative effects of methamphetamine and nicotine on the striatal [(11)C]raclopride binding in unanesthetized monkeys. Synapse (New York, N.Y.). vol 45. issue 4. 2002-09-13. PMID:12125041. |
these results indicate that nicotine, in high tobacco-smoking-related doses, does not release sufficient brain dopamine to displace [(11)c]raclopride in the striatum in the awake and fully conscious state, in contrast to small doses of methamphetamine. |
2002-09-13 |
2023-08-12 |
monkey |
| R K Kurup, R Nair, P A Kuru. Hypothalamic digoxin mediated model for oncogenesis. Journal of experimental & clinical cancer research : CR. vol 20. issue 4. 2002-09-06. PMID:11876554. |
serum tryptophan, serotonin, nicotine and quinolinic acid were elevated while tyrosine, dopamine, noradrenaline and morphine were decreased. |
2002-09-06 |
2023-08-12 |
Not clear |
| R K Kurup, R Nair, P A Kuru. Hypothalamic digoxin mediated model for oncogenesis. Journal of experimental & clinical cancer research : CR. vol 20. issue 4. 2002-09-06. PMID:11876554. |
digoxin induced tryptophan/tyrosine transport defect can alter neurotransmitter patterns with increased serotonin, quinolinic acid, nicotine & glutamatergic transmission and reduced dopamine, morphine and noradrenaline levels leading to oncogenesis. |
2002-09-06 |
2023-08-12 |
Not clear |
| R Ferrari, N Le Novère, M R Picciotto, J P Changeux, M Zol. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European journal of neuroscience. vol 15. issue 11. 2002-09-04. PMID:12081661. |
we have examined several neurochemical and behavioural parameters related to the function of the mesolimbic dopamine (da) pathway in animals treated with nicotine following three modes of drug administration, i.e. |
2002-09-04 |
2023-08-12 |
Not clear |
| R Ferrari, N Le Novère, M R Picciotto, J P Changeux, M Zol. Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections. The European journal of neuroscience. vol 15. issue 11. 2002-09-04. PMID:12081661. |
in addition, significant increases in tyrosine hydroxylase (th) and glur1 (but not dopamine transporter or nr1) mrna levels in the vta were detected 24 h after intra-vta nicotine administration. |
2002-09-04 |
2023-08-12 |
Not clear |
| Sean P David, Elaine Johnstone, Siân-Elin Griffiths, Michael Murphy, Patricia Yudkin, David Mant, Robert Walto. No association between functional catechol O-methyl transferase 1947A>G polymorphism and smoking initiation, persistent smoking or smoking cessation. Pharmacogenetics. vol 12. issue 3. 2002-09-03. PMID:11927842. |
nicotine stimulates dopamine release and activates dopaminergic reward neurones in central pathways giving rise to dependence. |
2002-09-03 |
2023-08-12 |
Not clear |