| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Hirohashi, K Takasuna, Y Kasai, C Usui, K Tamura, H Kojim. General pharmacological profile of the new anti-ulcer drug 3-[[[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl]methyl]-amino-N -methylbenzamide. Arzneimittel-Forschung. vol 43. issue 5. 1993-08-11. PMID:8329002. |
dq-2511 reduced contractile responses to nicotine, bacl2, acetylcholine, histamine and serotonin (isolated guinea pig ileum), to acetylcholine and histamine (trachea), and to norepinephrine (vas deferens) at high concentrations. |
1993-08-11 |
2023-08-12 |
mouse |
| J J Buccafusco, X Yan. Mechanism of the hypertensive response to central injection of nicotine in conscious rats. Brain research bulletin. vol 32. issue 1. 1993-08-03. PMID:8319101. |
also, because nicotine has been reported to enhance the release of endogenous brain acetylcholine, we sought to determine the role of this mechanism in mediating the cardiovascular response. |
1993-08-03 |
2023-08-12 |
rat |
| J J Buccafusco, X Yan. Mechanism of the hypertensive response to central injection of nicotine in conscious rats. Brain research bulletin. vol 32. issue 1. 1993-08-03. PMID:8319101. |
in order to examine the dependence of the pressor response to nicotine on brain acetylcholine, rats were pretreated with 20 micrograms (icv) of hemicholinium-3 (hc-3) 1 h prior to nicotine to deplete endogenous acetylcholine. |
1993-08-03 |
2023-08-12 |
rat |
| J J Buccafusco, X Yan. Mechanism of the hypertensive response to central injection of nicotine in conscious rats. Brain research bulletin. vol 32. issue 1. 1993-08-03. PMID:8319101. |
nicotine enhanced the release of [3h]acetylcholine from brain slices in vitro at concentrations likely achieved in the in vivo studies. |
1993-08-03 |
2023-08-12 |
rat |
| R L Siblerud, E Kienholz, J Mot. Evidence that mercury from silver dental fillings may be an etiological factor in smoking. Toxicology letters. vol 68. issue 3. 1993-07-19. PMID:8516784. |
because mercury decreases dopamine, serotonin, norepinephrine, and acetylcholine in the brain, and nicotine has just the opposite effect on these neurotransmitters, this may help explain why persons with dental amalgams smoke more than persons without amalgams. |
1993-07-19 |
2023-08-12 |
human |
| F Leboulenger, M Buda, M Morra, L Vaglini, A Fasolo, H Vaudr. In vitro study of catecholamine release from perifused frog adrenal slices. General and comparative endocrinology. vol 90. issue 1. 1993-07-08. PMID:8504914. |
similarly, the selective cholinergic agonists muscarine and nicotine did not significantly affect catecholamine release, while muscarine mimicked the stimulatory action of acetylcholine on corticosterone secretion. |
1993-07-08 |
2023-08-12 |
Not clear |
| R J Lewis, A W Ho. Comparative action of three major ciguatoxins on guinea-pig atria and ilea. Toxicon : official journal of the International Society on Toxinology. vol 31. issue 4. 1993-06-28. PMID:8503132. |
each ciguatoxin significantly reduced the contractile response of ilea to nicotine, without affecting the contractile response to acetylcholine. |
1993-06-28 |
2023-08-12 |
Not clear |
| B Yazejian, G L Fai. Whole-cell currents activated at nicotinic acetylcholine receptors on ganglion cells isolated from goldfish retina. Visual neuroscience. vol 10. issue 2. 1993-06-07. PMID:8485097. |
we have recorded whole-cell membrane currents in response to exogenously applied acetylcholine (ach), nicotine, and 1,1 dimethyl-4-phenyl piperazinium iodide on retinal ganglion cells enzymatically dissociated from goldfish retina. |
1993-06-07 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Tachykinin receptors of the NK2 type involved in the acetylcholine release by nicotine in guinea-pig bladder. British journal of pharmacology. vol 108. issue 3. 1993-05-13. PMID:8385536. |
tachykinin receptors of the nk2 type involved in the acetylcholine release by nicotine in guinea-pig bladder. |
1993-05-13 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Tachykinin receptors of the NK2 type involved in the acetylcholine release by nicotine in guinea-pig bladder. British journal of pharmacology. vol 108. issue 3. 1993-05-13. PMID:8385536. |
acetylcholine release and the contractile response stimulated by nicotine were partially reduced by a sympathetic nerve blocker, guanethidine. |
1993-05-13 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Tachykinin receptors of the NK2 type involved in the acetylcholine release by nicotine in guinea-pig bladder. British journal of pharmacology. vol 108. issue 3. 1993-05-13. PMID:8385536. |
neurokinin a (but not substance p methyl ester or senktide) enhanced both acetylcholine release and contraction by nicotine in the presence of guanethidine. |
1993-05-13 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Tachykinin receptors of the NK2 type involved in the acetylcholine release by nicotine in guinea-pig bladder. British journal of pharmacology. vol 108. issue 3. 1993-05-13. PMID:8385536. |
we conclude that the ability of nicotine to release acetylcholine is enhanced both by endogenous tachykinins (probably released from sympathetic nerves) and by exogenously applied tachykinins as a result of interaction with nk2 receptors in the urinary bladder. |
1993-05-13 |
2023-08-12 |
Not clear |
| Y Fukunaga, Y Mine, S Yoshikawa, T Takeuchi, F Hata, O Yagasak. Role of prostacyclin in acetylcholine release from myenteric plexus of guinea-pig ileum. European journal of pharmacology. vol 233. issue 2-3. 1993-05-11. PMID:8467869. |
indomethacin significantly decreased both spontaneous acetylcholine release and its release induced by nicotine and substance p. we had found that prostaglandin e2 (pge2) partly reversed this inhibition. |
1993-05-11 |
2023-08-12 |
Not clear |
| Y Fukunaga, Y Mine, S Yoshikawa, T Takeuchi, F Hata, O Yagasak. Role of prostacyclin in acetylcholine release from myenteric plexus of guinea-pig ileum. European journal of pharmacology. vol 233. issue 2-3. 1993-05-11. PMID:8467869. |
op-41483 had no effect on acetylcholine release induced by nicotine or substance p in the absence of indomethacin. |
1993-05-11 |
2023-08-12 |
Not clear |
| F Grassi, A Giovannelli, S Fucile, F Euseb. Activation of the nicotinic acetylcholine receptor mobilizes calcium from caffeine-insensitive stores in C2C12 mouse myotubes. Pflugers Archiv : European journal of physiology. vol 422. issue 6. 1993-05-07. PMID:8469610. |
in cultured mouse c2c12 myotubes, digital ca2+ imaging fluorescence microscopy using the acetoxymethyl ester of fura-2, fura-2-am, showed that, in the absence of extracellular ca2+, acetylcholine (ach) and nicotine, but not muscarine, raised the intracellular concentration of ca2+ ([ca2+]i) by about tenfold. |
1993-05-07 |
2023-08-12 |
mouse |
| J D Minn. The molecular biology of lung cancer pathogenesis. Chest. vol 103. issue 4 Suppl. 1993-05-03. PMID:8462339. |
in addition, they express a negative autocrine loop involving opioids and their receptors which is reversed by nicotine acting through nicotinic acetylcholine receptors. |
1993-05-03 |
2023-08-12 |
Not clear |
| M A Segerberg, A O Stretto. Actions of cholinergic drugs in the nematode Ascaris suum. Complex pharmacology of muscle and motorneurons. The Journal of general physiology. vol 101. issue 2. 1993-04-20. PMID:8455017. |
the cholinergic agonists acetylcholine (ach), nicotine, and pilocarpine produced depolarizations and contractions of muscle of the nematode ascaris suum. |
1993-04-20 |
2023-08-12 |
caenorhabditis_elegans |
| M Hall, L Zerbe, S Leonard, R Freedma. Characterization of [3H]cytisine binding to human brain membrane preparations. Brain research. vol 600. issue 1. 1993-02-25. PMID:8422580. |
nicotine and acetylcholine were also potent displacers with ki values of 1.8 and 8.1 nm, respectively. |
1993-02-25 |
2023-08-12 |
human |
| S Nakamura, Y Goshima, J L Yue, T Miyamae, Y Mis. Transmitter-like 3,4-dihydroxyphenylalanine is tonically released by nicotine in striata of conscious rats. European journal of pharmacology. vol 222. issue 1. 1993-01-22. PMID:1361443. |
nicotine released stereoselectively endogenous dopa via nicotinic acetylcholine receptors from striata of freely moving rats in a manner similar to transmitter da. |
1993-01-22 |
2023-08-11 |
rat |
| J Gould, H L Reeve, P F Vaughan, C Peer. Nicotinic acetylcholine receptors in human neuroblastoma (SH-SY5Y) cells. Neuroscience letters. vol 145. issue 2. 1993-01-19. PMID:1465217. |
acetylcholine, nicotine and the neuronal nachr agonist dimethylphenylpiperazinium iodide (dmpp), but not muscarine, all evoked inward currents in the cells (voltage-clamped at -60 mv). |
1993-01-19 |
2023-08-11 |
human |