| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Alkondon, E X Albuquerqu. Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons. Journal of receptor research. vol 11. issue 6. 1992-01-28. PMID:1753378. |
the nicotinic agonists acetylcholine, (+)anatoxin-a, and (-) and (+)nicotine all evoked inward whole-cell currents in hippocampal neurons that were voltage clamped near their resting potentials. |
1992-01-28 |
2023-08-11 |
rat |
| B V Sastr. Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function. Reproduction, fertility, and development. vol 3. issue 4. 1992-01-02. PMID:1957023. |
nicotine blocks the cholinergic receptor and thus blocks acetylcholine (ach)-facilitated amino-acid transport. |
1992-01-02 |
2023-08-11 |
human |
| E G Delicado, R P Sen, M T Miras-Portuga. Effects of phorbol esters and secretagogues on nitrobenzylthioinosine binding to nucleoside transporters and nucleoside uptake in cultured chromaffin cells. The Biochemical journal. vol 279 ( Pt 3). 1991-12-16. PMID:1953658. |
the inhibition caused by carbachol, nicotine and acetylcholine reached 50%. |
1991-12-16 |
2023-08-11 |
cattle |
| E Aizenman, L H Tang, I J Reynold. Effects of nicotinic agonists on the NMDA receptor. Brain research. vol 551. issue 1-2. 1991-11-01. PMID:1833030. |
in addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, were able to displace [3h]dizocilpine ([3h]mk 801) binding in well-washed membranes obtained from rat brain. |
1991-11-01 |
2023-08-11 |
rat |
| K Saegusa, Y Furukawa, K Akahane, M Haniuda, S Chib. Anti-nicotinic and anti-muscarinic actions of eperisone in the isolated canine atrium. Japanese journal of pharmacology. vol 56. issue 2. 1991-10-03. PMID:1880997. |
the effects of eperisone, an antispastic agent, on the chronotropic and inotropic responses to acetylcholine, nicotine or stimulation of intracardiac autonomic nerves were evaluated in isolated, blood-perfused canine atrium. |
1991-10-03 |
2023-08-11 |
dog |
| K Saegusa, Y Furukawa, K Akahane, M Haniuda, S Chib. Anti-nicotinic and anti-muscarinic actions of eperisone in the isolated canine atrium. Japanese journal of pharmacology. vol 56. issue 2. 1991-10-03. PMID:1880997. |
the inhibitory effect persisted much longer for the responses to nicotine or parasympathetic stimulation than for those to acetylcholine. |
1991-10-03 |
2023-08-11 |
dog |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. |
1991-09-27 |
2023-08-11 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
contractile responses and acetylcholine release evoked by nicotine in guinea-pig detrusor strips were determined by isotonic transducer and radioimmunoassay, respectively. |
1991-09-27 |
2023-08-11 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
nicotine stimulated acetylcholine release and a contractile response in guinea-pig detrusor strips treated with the cholinesterase inhibitor, methanesulphonyl fluoride (msf). |
1991-09-27 |
2023-08-11 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
a sympathetic nerve blocker, guanethidine and a tachykinin antagonist, [d-arg1, d-pro2, d-trp7,9, leu11]-substance p (rpwwl-sp) partially inhibited the acetylcholine release evoked by nicotine to much the same degree. |
1991-09-27 |
2023-08-11 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
the inhibitory effects of guanethidine and rpwwl-sp on acetylcholine release were significantly greater than corresponding effects on the contraction evoked by nicotine. |
1991-09-27 |
2023-08-11 |
Not clear |
| M Shinkai, I Takayanagi, T Kat. Contrasting effects of tachykinins and guanethidine on the acetylcholine output stimulated by nicotine from guinea-pig bladder [corrected]. British journal of pharmacology. vol 103. issue 1. 1991-09-27. PMID:1715227. |
our findings give further support to our previous results: nicotine stimulates acetylcholine release in a tetrodotoxin-resistant manner in guinea-pig bladder and acetylcholine release evoked by nicotine is increased by the coordinated action of sympathetic nerves and tachykinin(s). |
1991-09-27 |
2023-08-11 |
Not clear |
| O Kadlec, I Seferna, J Sevcí. An attempt to localize the site of action of different agents within cholinergic motor neurones of the myenteric plexus-longitudinal muscle preparation of the guinea pig ileum by the triple bath method. Neuropharmacology. vol 30. issue 5. 1991-09-11. PMID:1714055. |
noradrenaline and ethylketocyclazocine were more effective at the site of varicose nerve terminals, whereas substance p, acetylcholine and oxotremorine were more effective at the proximal parts; pilocarpine and nicotine were effective at both sites. |
1991-09-11 |
2023-08-11 |
Not clear |
| R E Middleton, J B Cohe. Mapping of the acetylcholine binding site of the nicotinic acetylcholine receptor: [3H]nicotine as an agonist photoaffinity label. Biochemistry. vol 30. issue 28. 1991-08-22. PMID:2069955. |
mapping of the acetylcholine binding site of the nicotinic acetylcholine receptor: [3h]nicotine as an agonist photoaffinity label. |
1991-08-22 |
2023-08-11 |
Not clear |
| R E Middleton, J B Cohe. Mapping of the acetylcholine binding site of the nicotinic acetylcholine receptor: [3H]nicotine as an agonist photoaffinity label. Biochemistry. vol 30. issue 28. 1991-08-22. PMID:2069955. |
the agonist [3h]nicotine was used as a photoaffinity label for the acetylcholine binding sites on the torpedo nicotinic acetylcholine receptor (achr). |
1991-08-22 |
2023-08-11 |
Not clear |
| C H Cho, G W Te. The inhibitory action of zinc sulphate on the contractile activity of guinea-pig ileum. The Journal of pharmacy and pharmacology. vol 43. issue 4. 1991-08-15. PMID:1676749. |
preincubation of ileum with znso4 1 x 10(-3) or 3 x 10(-3) m for 10 min dose-dependently and significantly prevented the contraction induced by acetylcholine (1.7 x 10(-8) m), 5-ht (2.4 x 10(-6) m), histamine (5.4 x 10(-7) m) and nicotine (1.7 x 10(-6) m) but not by prostaglandin e2 (pge2, 8.5 x 10(-9) m). |
1991-08-15 |
2023-08-11 |
Not clear |
| L A Wong, J P Gallaghe. Pharmacology of nicotinic receptor-mediated inhibition in rat dorsolateral septal neurones. The Journal of physiology. vol 436. 1991-08-08. PMID:2061835. |
acetylcholine (in the presence of the muscarinic antagonist, atropine), nicotine or dimethylphenylpiperazinium (dmpp), applied either by pressure ejection or superfusion, produced predominantly a membrane potential hyperpolarization. |
1991-08-08 |
2023-08-11 |
rat |
| L M Rosario, A Stutzin, E J Cragoe, H B Pollar. Modulation of intracellular pH by secretagogues and the Na+/H+ antiporter in cultured bovine chromaffin cells. Neuroscience. vol 41. issue 1. 1991-07-29. PMID:1647503. |
stimulation with both cholinergic agonists (acetylcholine, nicotine) and a depolarizing agent (high k+) transiently acidified the cytosol of the chromaffin cell. |
1991-07-29 |
2023-08-11 |
cattle |
| M Hirohashi, K Takasuna, Y Kasai, C Usui, H Kojim. Pharmacological studies with the alpha 2-adrenoceptor antagonist midaglizole. Part III: Smooth muscle, gastrointestinal and miscellaneous systems. Arzneimittel-Forschung. vol 41. issue 1. 1991-07-15. PMID:1675570. |
isolated smooth muscle: midaglizole inhibited the contractile responses of the ileum to nicotine, acetylcholine, serotonin and bacl2, and especially the response to histamine (guinea pig). |
1991-07-15 |
2023-08-11 |
mouse |
| R Anand, W G Conroy, R Schoepfer, P Whiting, J Lindstro. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. The Journal of biological chemistry. vol 266. issue 17. 1991-07-10. PMID:2040627. |
we also show that these expressed receptors bind l-[3h]nicotine with high affinity, are transported to the surface of the oocyte outer membrane, and cosediment on sucrose gradients with acetylcholine receptors isolated from chicken brain. |
1991-07-10 |
2023-08-11 |
human |