| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R E Loiacono, F J Mitchelso. Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 1. 1990-10-23. PMID:2402302. |
in the presence of idazoxan (0.3 microm) plus atropine (0.1 microm), nicotine (3 microm) continued to enhance evoked [3h]acetylcholine release while the inhibitory effect of tacrine (1 microm) on evoked [3h]acetylcholine release was reversed to an enhancement. |
1990-10-23 |
2023-08-11 |
rat |
| R E Loiacono, F J Mitchelso. Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 1. 1990-10-23. PMID:2402302. |
under conditions where both presynaptic inhibitory muscarine and alpha 2-adrenoceptors are blocked, the elevated levels of acetylcholine produced by tacrine will lead to the activation of facilitatory presynaptic nicotine cholinoceptors on cholinergic nerves and an enhancement of evoked [3h]acetylcholine release. |
1990-10-23 |
2023-08-11 |
rat |
| H M Schüller, E Nylen, P Park, K L Becke. Nicotine, acetylcholine and bombesin are trophic growth factors in neuroendocrine cell lines derived from experimental hamster lung tumors. Life sciences. vol 47. issue 6. 1990-10-22. PMID:1698239. |
nicotine, acetylcholine and bombesin are trophic growth factors in neuroendocrine cell lines derived from experimental hamster lung tumors. |
1990-10-22 |
2023-08-11 |
human |
| H M Schüller, E Nylen, P Park, K L Becke. Nicotine, acetylcholine and bombesin are trophic growth factors in neuroendocrine cell lines derived from experimental hamster lung tumors. Life sciences. vol 47. issue 6. 1990-10-22. PMID:1698239. |
in keeping with data previously reported for a human neuroendocrine lung tumor cell line, nicotine, acetylcholine, and mammalian bombesin (mb) acted as strong growth factors in these neuroendocrine hamster tumor lines. |
1990-10-22 |
2023-08-11 |
human |
| H M Schüller, E Nylen, P Park, K L Becke. Nicotine, acetylcholine and bombesin are trophic growth factors in neuroendocrine cell lines derived from experimental hamster lung tumors. Life sciences. vol 47. issue 6. 1990-10-22. PMID:1698239. |
the mitogenic effect of nicotine and acetylcholine was abolished by nicotinic receptor inhibition while the effects of mammalian bombesin were inhibited by an antagonist of mb receptors. |
1990-10-22 |
2023-08-11 |
human |
| C W Luetje, J Patrick, P Séguél. Nicotine receptors in the mammalian brain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 4. issue 10. 1990-08-30. PMID:2197155. |
in this review we focus on the neuronal nicotinic acetylcholine receptors, their diversity, distribution, and functions as nicotine receptors or as mediators of synaptic transmission in the mammalian brain. |
1990-08-30 |
2023-08-11 |
Not clear |
| V Barrios, M N Rodriguez-Sanchez, B Colas, E Arill. Effects of acute nicotine and mecamylamine administration on somatostatin concentration and binding in the rat brain. European journal of pharmacology. vol 179. issue 3. 1990-08-13. PMID:1973104. |
to determine if the above mentioned changes are related to the nicotine activation of central nicotine-like acetylcholine receptors, a cholinergic nicotinic blocking agent, mecamylamine, was administered before the nicotine injection. |
1990-08-13 |
2023-08-11 |
rat |
| V Barrios, M N Rodriguez-Sanchez, B Colas, E Arill. Effects of acute nicotine and mecamylamine administration on somatostatin concentration and binding in the rat brain. European journal of pharmacology. vol 179. issue 3. 1990-08-13. PMID:1973104. |
these results suggest that the somatostatinergic system can be regulated by nicotine-like acetylcholine receptors and may be involved in some of the behavioral central effects of nicotine. |
1990-08-13 |
2023-08-11 |
rat |
| A R Tabassian, E S Nylen, L Lukacs, M M Cassidy, K L Becke. Cholinergic regulation of hamster pulmonary neuroendocrine cell calcitonin. Experimental lung research. vol 16. issue 3. 1990-08-02. PMID:2357949. |
furthermore, the subcutaneous injection of acetylcholine was found to mimic the effect noted for nicotine; this was also abolished by prior administration of a nicotinic antagonist, but not by a muscarinic antagonist. |
1990-08-02 |
2023-08-11 |
Not clear |
| Y Fraenkel, G Navon, A Aronheim, J M Gershon. Direct measurement of agonist binding to genetically engineered peptides of the acetylcholine receptor by selective T1 NMR relaxation. Biochemistry. vol 29. issue 10. 1990-06-14. PMID:2334686. |
the kd values for the binding of acetylcholine, nicotine, d-tubocurarine, and gallamine to the affinity-purified construct were 1.4, 1.4, 0.20, and 0.21 mm, respectively, while kd's with the nontoxin binding protein were all above 10 mm. |
1990-06-14 |
2023-08-11 |
Not clear |
| M K Stachowiak, J S Hong, O H Vivero. Coordinate and differential regulation of phenylethanolamine N-methyltransferase, tyrosine hydroxylase and proenkephalin mRNAs by neural and hormonal mechanisms in cultured bovine adrenal medullary cells. Brain research. vol 510. issue 2. 1990-06-04. PMID:1970506. |
acetylcholine or nicotine reduced cellular content of catecholamines by 30% and increased the relative abundance of pek, th, and pnmt mrnas. |
1990-06-04 |
2023-08-11 |
cattle |
| Y Kizawa, M Shinkai, I Takayanag. Effects of chronic nicotine treatment on nicotinic receptors in the rabbit urinary bladder. Canadian journal of physiology and pharmacology. vol 68. issue 1. 1990-05-29. PMID:2328448. |
these findings suggest that the response to nicotine is due to acetylcholine, tachykinins, and unknown mediator release. |
1990-05-29 |
2023-08-11 |
rabbit |
| D C Thompson, R J Altiere, L Diamon. Nicotinic agonist modulation of feline bronchomotor tone. Clinical and experimental pharmacology & physiology. vol 17. issue 2. 1990-05-29. PMID:2328544. |
dmpp-induced bronchodilator responses were adrenergic in nature, whereas those induced by either nicotine or acetylcholine resulted from a combination of adrenergic and non-adrenergic influences. |
1990-05-29 |
2023-08-11 |
Not clear |
| G Oettling, G Bruchelt, F Lohmann, M Teufel, D Niethammer, J Treuner, U Drew. Vasoactive intestinal polypeptide (VIP) induces calcium mobilization in the human neuroblastoma cell line SK-N-SH. Cancer letters. vol 50. issue 3. 1990-05-11. PMID:2322933. |
we found that vasoactive intestinal polypeptide (vip), in addition to acetylcholine and muscarine (but not nicotine), causes elevation of the cytoplasmic ca2(+)-concentration in the highly differentiated human neuroblastoma cell line sk-n-sh, with or without the presence of extracellular ca2+. |
1990-05-11 |
2023-08-11 |
human |
| K Yokoyama, O Yagasak. Effects of Ca2+ blockers on the various types of stimuli-induced acetylcholine release from guinea pig ileum myenteric plexus. Japanese journal of pharmacology. vol 52. issue 1. 1990-04-02. PMID:2308231. |
in the present study, we investigated the effects of various ca2+ blockers on the release of acetylcholine (ach) induced by nicotine, electrical field stimulation (efs) and high-k+. |
1990-04-02 |
2023-08-11 |
Not clear |
| T Hisayama, M Shinkai, I Takayanagi, T Toyod. Mechanism of action of nicotine in isolated urinary bladder of guinea-pig: involvement of tachykinin(s) released by nicotine in the drug's sympathomimetic effect. Archives internationales de pharmacodynamie et de therapie. vol 301. 1990-03-19. PMID:2483045. |
we previously suggested that nicotine may release acetylcholine and atp to contract the detrusor strips, and that acetylcholine output may be increased by an unknown substance released from the sympathetic nerve by nicotine. |
1990-03-19 |
2023-08-11 |
Not clear |
| T Hisayama, M Shinkai, I Takayanagi, T Toyod. Mechanism of action of nicotine in isolated urinary bladder of guinea-pig: involvement of tachykinin(s) released by nicotine in the drug's sympathomimetic effect. Archives internationales de pharmacodynamie et de therapie. vol 301. 1990-03-19. PMID:2483045. |
it is suggested that in guinea-pig detrusor, tachykinin(s) from capsaicin-insensitive sites is (are) involved in the excitatory sympathomimetic effect of nicotine, and that the tachykinin(s) behave(s) as a modulator finally to increase the acetylcholine output from the parasympathetic cholinergic nerve. |
1990-03-19 |
2023-08-11 |
Not clear |
| M Sorimachi, K Yamagami, T Yada, S Nishimur. Spontaneous and secretagogue-induced changes in cytosolic free Ca concentration measured by microfluorimetry with fura-2 on single bovine adrenal chromaffin cells. The Japanese journal of physiology. vol 39. issue 5. 1990-03-14. PMID:2482378. |
low concentrations of nicotine (1 microm), acetylcholine (ach; 1-2 microm), or kcl (12.5 mm) often induced oscillations riding on a steady rise in [ca]in. |
1990-03-14 |
2023-08-11 |
cattle |
| B A Hulihan-Giblin, M D Lumpkin, K J Kella. Effects of chronic administration of nicotine on prolactin release in the rat: inactivation of prolactin response by repeated injections of nicotine. The Journal of pharmacology and experimental therapeutics. vol 252. issue 1. 1990-03-12. PMID:2299591. |
the effects of chronic injections of nicotine on nicotine-induced prolactin release in the rat were measured and compared to the effects of this treatment on [3h]acetylcholine binding to nicotinic cholinergic sites in the hypothalamus. |
1990-03-12 |
2023-08-11 |
rat |
| B A Hulihan-Giblin, M D Lumpkin, K J Kella. Effects of chronic administration of nicotine on prolactin release in the rat: inactivation of prolactin response by repeated injections of nicotine. The Journal of pharmacology and experimental therapeutics. vol 252. issue 1. 1990-03-12. PMID:2299591. |
at each of these time points, the binding of [3h]acetylcholine in the hypothalamus from rats treated chronically with nicotine was significantly higher than in the hypothalamus from control rats. |
1990-03-12 |
2023-08-11 |
rat |