| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Falugi, G Prestipin. Localization of putative nicotinic cholinoreceptors in the early development of Paracentrotus lividus. Cellular and molecular biology. vol 35. issue 2. 1989-07-17. PMID:2731192. |
1 mm acetylcholine (ach), 100 microm nicotine, 100 nm alpha-bungarotoxin (alpha-butx) and 100 microm curare inhibit sperm motility and fertilization, while they have no effect on unfertilized eggs. |
1989-07-17 |
2023-08-11 |
Not clear |
| D C Smith, D V Priol. Enhanced acetylcholine release from denervated atria: intrinsic neural supersensitivity. European journal of pharmacology. vol 161. issue 2-3. 1989-07-07. PMID:2721557. |
when compared with controls, nicotine released more acetylcholine (ach) from denervated atria at 10(-5) and 2 x 10(-5) m, but not at 5 x 10(-5) m. in parallel contractility studies using tissue from these same atria, the negative inotropic response to nicotine was enhanced at 5 x 10(-6) and 10(-5) m, but not at 2 x 10(-5) or 5 x 10(-5) m nicotine. |
1989-07-07 |
2023-08-11 |
dog |
| C Vidal, J P Changeu. Pharmacological profile of nicotinic acetylcholine receptors in the rat prefrontal cortex: an electrophysiological study in a slice preparation. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2725858. |
the specificity of nicotinic receptors in the neocortex has been questioned previously because: (i) electrophysiological responses to nicotine could not be blocked by nicotinic antagonists, and (ii) the effect of nicotine was not mimicked by acetylcholine. |
1989-07-07 |
2023-08-11 |
rat |
| R Quirion, D Araujo, W Regenold, P Boks. Characterization and quantitative autoradiographic distribution of [3H]acetylcholine muscarinic receptors in mammalian brain. Apparent labelling of an M2-like receptor sub-type. Neuroscience. vol 29. issue 2. 1989-07-07. PMID:2725859. |
the ligand selectivity pattern reveals that the potency of (-)quinuclidinyl benzylate is greater than (greater than) atropine greater than scopolamine greater than oxotremorine greater than carbamylcholine greater than pirenzepine greater than methylcarbamyl-choline = nicotine in competing for [3h]acetylcholine binding sites, indicating that [3h]acetylcholine selectively binds to muscarinic sites under these incubation conditions. |
1989-07-07 |
2023-08-11 |
rat |
| M Yamaya, K Zayasu, K Sekizawa, K Yamauchi, S Shimura, H Sasaki, T Takishim. Acute effect of cigarette smoke on cytoplasmic motility of alveolar macrophages in dogs. Journal of applied physiology (Bethesda, Md. : 1985). vol 66. issue 3. 1989-06-02. PMID:2468640. |
nicotine injection and acetylcholine inhalation increased respiratory resistance to a degree similar to that observed with cigarette smoke but did not change lambda 0. |
1989-06-02 |
2023-08-11 |
Not clear |
| Y Yamada, Y Nakazato, A Ohg. Ouabain distinguishes between nicotinic and muscarinic receptor-mediated catecholamine secretions in perfused adrenal glands of cat. British journal of pharmacology. vol 96. issue 2. 1989-05-05. PMID:2924087. |
acetylcholine (ach) (5 x 10(-7) to 10(-3) m), pilocarpine (10(-5) to 10(-3) m) and nicotine (10(-6) to 5 x 10(-5) m) caused dose-dependent increases in catecholamine secretion. |
1989-05-05 |
2023-08-11 |
cat |
| b' A Simoni\\xc4\\x87, J Roganovi\\xc4\\x87-Dordevi\\xc4\\x87, V Golubovi\\xc4\\x8. Influence of various cholinergic and anticholinergic drugs on rectal temperature in rats. Archives internationales de pharmacodynamie et de therapie. vol 294. 1989-04-14. PMID:3233052.' |
three hours later acetylcholine, methacholine, arecoline, nicotine, neostigmine, atropine, methylatropine, mecamylamine or hemicholinium were injected intrahypothalamically (i.h. |
1989-04-14 |
2023-08-11 |
rat |
| T D Hexum, L R Russet. Stimulation of cholinergic receptor mediated secretion from the bovine adrenal medulla by neuropeptide Y. Neuropeptides. vol 13. issue 1. 1989-04-11. PMID:2922105. |
the stimulatory action of other cholinergic agonists (nicotine and acetylcholine) was likewise potentiated by the addition of the neuropeptide. |
1989-04-11 |
2023-08-11 |
cattle |
| D Parkinson, K E Kratz, N W Da. Evidence for a nicotinic component to the actions of acetylcholine in cat visual cortex. Experimental brain research. vol 73. issue 3. 1989-03-29. PMID:3224664. |
iontophoresis of mecamylamine, a nicotinic antagonist, decreased evoked responses in visual cortex, providing evidence that the [3h]nicotine binding sites are functional receptors and suggesting that the release of acetylcholine onto these receptors on the lgn terminals facilitates the input of visual information into visual cortex. |
1989-03-29 |
2023-08-11 |
cat |
| A Härfstrand, A Adem, K Fuxe, L Agnati, K Andersson, A Nordber. Distribution of nicotinic cholinergic receptors in the rat tel- and diencephalon: a quantitative receptor autoradiographical study using [3H]-acetylcholine, [alpha-125I]bungarotoxin and [3H]nicotine. Acta physiologica Scandinavica. vol 132. issue 1. 1989-03-21. PMID:3223299. |
the topographical distribution of [alpha-125i]bungarotoxin [125i]btx, [3h]nicotine ([3h]nic), [3h]acetylcholine ([3h]ach) (in the presence of atropine) binding in rat tel- and diencephalon was investigated using a quantitative receptor autoradiographical technique. |
1989-03-21 |
2023-08-11 |
rat |
| M Bommer, A Her. Neurotensin affects metabolism of opioid peptides, catecholamines and inositol phospholipids in bovine chromaffin cells. Life sciences. vol 44. issue 5. 1989-03-17. PMID:2915604. |
dose-response curves for neurotensin-induced secretion revealed an ec50 of 1x10(-6)m, thereby being in the range of that for acetylcholine or nicotine. |
1989-03-17 |
2023-08-11 |
cattle |
| J A Benso. Bicuculline blocks the response to acetylcholine and nicotine but not to muscarine or GABA in isolated insect neuronal somata. Brain research. vol 458. issue 1. 1989-02-22. PMID:3208101. |
bicuculline blocks the response to acetylcholine and nicotine but not to muscarine or gaba in isolated insect neuronal somata. |
1989-02-22 |
2023-08-11 |
Not clear |
| M Jung, A Perio, P Worms, P Soubri. Pharmacological characterization of the physostigmine stimulus in rats. Psychopharmacology. vol 95. issue 4. 1989-02-21. PMID:3145526. |
there was generalization to the acetylcholine esterase inhibitor tha as well as to the muscarinic receptor agonists arecoline, oxotremorine and rs 86, but not to neostigmine or nicotine. |
1989-02-21 |
2023-08-11 |
rat |
| L Hösli, E Hösli, G Della Briotta, L Quadri, L Heus. Action of acetylcholine, muscarine, nicotine and antagonists on the membrane potential of astrocytes in cultured rat brainstem and spinal cord. Neuroscience letters. vol 92. issue 2. 1988-12-21. PMID:3185987. |
action of acetylcholine, muscarine, nicotine and antagonists on the membrane potential of astrocytes in cultured rat brainstem and spinal cord. |
1988-12-21 |
2023-08-11 |
rat |
| L Hösli, E Hösli, G Della Briotta, L Quadri, L Heus. Action of acetylcholine, muscarine, nicotine and antagonists on the membrane potential of astrocytes in cultured rat brainstem and spinal cord. Neuroscience letters. vol 92. issue 2. 1988-12-21. PMID:3185987. |
the actions of acetylcholine, muscarine and nicotine on the membrane potential of astrocytes of cultured rat brainstem and spinal cord were examined. |
1988-12-21 |
2023-08-11 |
rat |
| P J Whiting, J M Lindstro. Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 9. 1988-11-18. PMID:3171681. |
neuronal acetylcholine receptors (achrs), which bind nicotine with high affinity but do not bind alpha-bungarotoxin (alpha bgt), have recently been immunoaffinity-purified from chicken (whiting and lindstrom, 1986a) and rat (whiting and lindstrom, 1987a) brain using monoclonal antibodies (mabs). |
1988-11-18 |
2023-08-11 |
human |
| J R Hammond, W F MacDonald, T D Whit. Evoked secretion of [3H]noradrenaline and ATP from nerve varicosities isolated from the myenteric plexus of the guinea pig ileum. Canadian journal of physiology and pharmacology. vol 66. issue 4. 1988-11-01. PMID:3167671. |
exposure of these varicosities to kcl, nicotine, or acetylcholine resulted in the ca2+ -dependent release of [3h]noradrenaline. |
1988-11-01 |
2023-08-11 |
Not clear |
| J R Hammond, W F MacDonald, T D Whit. Evoked secretion of [3H]noradrenaline and ATP from nerve varicosities isolated from the myenteric plexus of the guinea pig ileum. Canadian journal of physiology and pharmacology. vol 66. issue 4. 1988-11-01. PMID:3167671. |
nicotine, acetylcholine, kcl, and veratridine also released atp from these guinea pig ileal myenteric varicosities. |
1988-11-01 |
2023-08-11 |
Not clear |
| Y Nakazato, M A Oleshansky, P K Chian. Effects of muscarinic pharmacophores on the cholinergic regulation of catecholamine secretion from perfused adrenal glands. Archives internationales de pharmacodynamie et de therapie. vol 293. 1988-10-25. PMID:3421778. |
the effects of the muscarinic antagonists, atropine, aprophen, azaprophen and pirenzepine, on catecholamine secretion stimulated by acetylcholine (ach) and nicotine were studied using perfused and isolated guinea-pig adrenal glands. |
1988-10-25 |
2023-08-11 |
Not clear |
| V K Gribkoff, E P Christian, J H Robinson, S A Deadwyler, F E Dude. Cholinergic excitation of supraoptic neurons in hypothalamic slices of rat. Neuropharmacology. vol 27. issue 7. 1988-10-24. PMID:3419551. |
the actions of the cholinergic agonists acetylcholine (ach), nicotine (nic) and carbamylcholine (carb) were studied in the supraoptic nucleus with extracellular recordings from coronal slices of the hypothalamus of the rat. |
1988-10-24 |
2023-08-11 |
rat |