| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D B McKa. [3H]noradrenaline accumulation in cultured bovine adrenal medullary cells: modulation of accumulation by nicotine. Naunyn-Schmiedeberg's archives of pharmacology. vol 340. issue 6. 1990-03-12. PMID:2615853. |
nicotine and other stimulants of catecholamine release (acetylcholine and depolarizing k+ concentrations) were found to inhibit [3h]noradrenaline accumulation. |
1990-03-12 |
2023-08-11 |
cattle |
| A P Chandran, R K Marya, L K Sharm. Effect of ganglionic stimulating and blocking agents on the fast components of colonic myoelectrical activity in the rat. Canadian journal of physiology and pharmacology. vol 67. issue 10. 1990-03-09. PMID:2575446. |
it was observed that ganglionic stimulants, such as balloon inflation, and intra-arterial injections of acetylcholine and small amounts of nicotine, increased the spike activity and the frequency of medium fast activity without affecting fast activity. |
1990-03-09 |
2023-08-11 |
rat |
| D McNamara, D M Larson, S I Rapoport, T T Soncran. Preferential metabolic activation of subcortical brain areas by acute administration of nicotine to rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 1. 1990-03-01. PMID:2298836. |
effects of nicotine in the hindbrain were related anatomically to reported distributions of [3h]nicotine and [3h]acetylcholine but not [125i]alpha-bungarotoxin binding sites, implying that the former ligands label functional nicotine receptors. |
1990-03-01 |
2023-08-11 |
rat |
| K R Rogers, J J Valdes, M E Eldefraw. Acetylcholine receptor fiber-optic evanescent fluorosensor. Analytical biochemistry. vol 182. issue 2. 1990-02-22. PMID:2514612. |
specific fitc-alpha-bgt binding to the nachr protein on the optic fibers was inhibited by agonists (e.g., acetylcholine, nicotine, and carbamylcholine) and antagonists (e.g., pancuronium and d-tubocurarine) of the nachr and was insensitive to high salt concentrations (e.g., 154 mm nacl). |
1990-02-22 |
2023-08-11 |
cattle |
| B Sahakian, G Jones, R Levy, J Gray, D Warburto. The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type. The British journal of psychiatry : the journal of mental science. vol 154. 1990-02-01. PMID:2597885. |
these results suggest that nicotine may be acting on cortical mechanisms involved in visual perception and attention, and support the hypothesis that acetylcholine transmission modulates vigilance and discrimination. |
1990-02-01 |
2023-08-11 |
Not clear |
| I Takayanagi, K Koike, M Tagawa, E Mitsuhash. Some pharmacological properties of a new antitumor drug, CPT-11, in isolated muscle preparations. General pharmacology. vol 20. issue 6. 1990-01-25. PMID:2591705. |
cpt-11 potentiated the contractile responses of guinea-pig ileum to acetylcholine, nicotine, serotonin and bacl2. |
1990-01-25 |
2023-08-11 |
Not clear |
| L Beani, C Bianchi, L Ferraro, L Nilsson, A Nordberg, L Romanelli, P Spalluto, A Sundwall, S Tanganell. Effect of nicotine on the release of acetylcholine and amino acids in the brain. Progress in brain research. vol 79. 1990-01-10. PMID:2587741. |
effect of nicotine on the release of acetylcholine and amino acids in the brain. |
1990-01-10 |
2023-08-11 |
Not clear |
| J A Rosecrans, C A Stimler, J S Hendry, L T Meltze. Nicotine-induced tolerance and dependence in rats and mice: studies involving schedule-controlled behavior. Progress in brain research. vol 79. 1990-01-10. PMID:2587745. |
these data support the view that nicotine may be inducing its effects via at least two separate nicotinic receptors, one of which may be acetylcholine sensitive. |
1990-01-10 |
2023-08-11 |
mouse |
| T Kita, T Nakashim. [Tolerance and reverse tolerance of nicotine on spontaneous motor activity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 94. issue 2. 1989-12-21. PMID:2680832. |
although nicotinic acetylcholine receptors in the brain participate in the effects of nicotine, the development of tolerance and reverse tolerance is not sufficiently explained by changes in the receptor sites. |
1989-12-21 |
2023-08-11 |
rat |
| T Kita, T Nakashim. [Tolerance and reverse tolerance of nicotine on spontaneous motor activity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 94. issue 2. 1989-12-21. PMID:2680832. |
recently, neurochemical and behavioral studies have shown the possibility that reverse tolerance of nicotine on the spontaneous motor activity is probably concerned with the dopaminergic system through nicotinic acetylcholine receptors in the striatum or mesolimbic dopaminergic system of the rat brain. |
1989-12-21 |
2023-08-11 |
rat |
| E T Iwamot. Antinociception after nicotine administration into the mesopontine tegmentum of rats: evidence for muscarinic actions. The Journal of pharmacology and experimental therapeutics. vol 251. issue 2. 1989-12-21. PMID:2810106. |
one hour preinjection into the mesopontine tegmentum with 13.5 nmol of (-)-vesamicol, an agent which interferes with acetylcholine storage and/or release, markedly inhibited nicotine antinociception; only a 24% antinociceptive response could be elicited by nicotine in the hot-plate test whereas the nicotine a5o was increased 3-fold in the tail-flick test. |
1989-12-21 |
2023-08-11 |
rat |
| L A Chah. The effects of ruthenium red on the response of guinea-pig ileum to capsaicin. European journal of pharmacology. vol 169. issue 2-3. 1989-12-20. PMID:2478375. |
thus the effects of ruthenium red on the responses of the guinea-pig isolated ileum to capsaicin, acetylcholine (ach), substance p (sp) and nicotine were investigated. |
1989-12-20 |
2023-08-11 |
Not clear |
| P Calabresi, M G Lacey, R A Nort. Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording. British journal of pharmacology. vol 98. issue 1. 1989-12-19. PMID:2804543. |
nicotine (10-100 microm) and acetylcholine (ach) depolarized the neurones. |
1989-12-19 |
2023-08-11 |
rat |
| A Nordberg, L Romanelli, A Sundwall, C Bianchi, L Bean. Effect of acute and subchronic nicotine treatment on cortical acetylcholine release and on nicotinic receptors in rats and guinea-pigs. British journal of pharmacology. vol 98. issue 1. 1989-12-19. PMID:2804554. |
effect of acute and subchronic nicotine treatment on cortical acetylcholine release and on nicotinic receptors in rats and guinea-pigs. |
1989-12-19 |
2023-08-11 |
rat |
| A Nordberg, L Romanelli, A Sundwall, C Bianchi, L Bean. Effect of acute and subchronic nicotine treatment on cortical acetylcholine release and on nicotinic receptors in rats and guinea-pigs. British journal of pharmacology. vol 98. issue 1. 1989-12-19. PMID:2804554. |
the effect of acute and chronic (16 days) administration of nicotine on cortical acetylcholine (ach) release, gross behaviour and brain nicotinic binding sites was investigated in rats and guinea-pigs. |
1989-12-19 |
2023-08-11 |
rat |
| E D London, M J Ball, S B Walle. Nicotinic binding sites in cerebral cortex and hippocampus in Alzheimer's dementia. Neurochemical research. vol 14. issue 8. 1989-12-18. PMID:2812250. |
nicotinic binding was assayed with 20 nm [3h]acetylcholine [( 3h]ach) in the presence of atropine, or with 4 nm (-)-[3h]nicotine ((-)-[3h]nic). |
1989-12-18 |
2023-08-11 |
human |
| K Ballanyi, W R Schlu. Electrophysiological characterization of a nicotinic acetylcholine receptor on leech neuropile glial cells. Glia. vol 2. issue 5. 1989-12-01. PMID:2530172. |
as measured with conventional single-barrelled microelectrodes, acetylcholine (ach), nicotine, carbachol, tetramethylammonium (tma), and choline elicited concentration-dependent (10(-6)-5 x 10(-3) m) transient membrane depolarizations of up to 60 mv amplitude whereas muscarine (10(-6)-10(-3) m) did not affect em. |
1989-12-01 |
2023-08-11 |
Not clear |
| A S Pivovarov, G N Saganelidz. [Ionic mechanisms evoked by acetylcholine-, nicotine-, and muscarine-induced depolarization of Helix lucorum RPa4 neurons]. Neirofiziologiia = Neurophysiology. vol 21. issue 3. 1989-09-25. PMID:2475791. |
three cholinomimetics: acetylcholine, nicotine and muscarine were applied locally on soma of helix lucorum rpa4 neuron to study ionic nature of its depolarization. |
1989-09-25 |
2023-08-11 |
Not clear |
| M Bommer, A Her. Neuropeptides and other secretagogues in bovine chromaffin cells: their effect on opioid peptide metabolism. Neuropeptides. vol 13. issue 4. 1989-08-22. PMID:2747855. |
dose-response curves for angiotensin ii and bradykinin were shown to be double-sigmoidal, with the first ec50 in the nm range; much lower than that for acetylcholine, nicotine or histamine. |
1989-08-22 |
2023-08-11 |
cattle |
| R M Santos, E Roja. Muscarinic receptor modulation of glucose-induced electrical activity in mouse pancreatic B-cells. FEBS letters. vol 249. issue 2. 1989-07-28. PMID:2567680. |
the acetylcholine effects were mimicked by muscarine while nicotine had no effect on membrane potential. |
1989-07-28 |
2023-08-11 |
mouse |